Published in Nat Cell Biol on January 01, 2000
Single-molecule analysis of dynein processivity and stepping behavior. Cell (2006) 5.63
Differential regulation of dynein and kinesin motor proteins by tau. Science (2008) 4.29
Regulators of the cytoplasmic dynein motor. Nat Rev Mol Cell Biol (2009) 4.05
High accuracy 3D quantum dot tracking with multifocal plane microscopy for the study of fast intracellular dynamics in live cells. Biophys J (2008) 3.90
Force-induced bidirectional stepping of cytoplasmic dynein. Cell (2007) 3.31
Dynactin is required for bidirectional organelle transport. J Cell Biol (2003) 3.04
Coordination of opposite-polarity microtubule motors. J Cell Biol (2002) 3.04
Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradient. Cell (2008) 2.97
Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function. J Cell Biol (2002) 2.89
LIS1 and NudE induce a persistent dynein force-producing state. Cell (2010) 2.88
Overlapping hand-over-hand mechanism of single molecular motility of cytoplasmic dynein. Proc Natl Acad Sci U S A (2006) 2.87
Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors. Proc Natl Acad Sci U S A (2008) 2.79
Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol Biol Cell (1999) 2.72
Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes. Proc Natl Acad Sci U S A (2009) 2.69
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci (2012) 2.68
A role for regulated binding of p150(Glued) to microtubule plus ends in organelle transport. J Cell Biol (2002) 2.68
The role of the lissencephaly protein Pac1 during nuclear migration in budding yeast. J Cell Biol (2003) 2.65
Function of dynein and dynactin in herpes simplex virus capsid transport. Mol Biol Cell (2002) 2.61
Efficient active transport of gene nanocarriers to the cell nucleus. Proc Natl Acad Sci U S A (2003) 2.52
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin. J Cell Biol (2007) 2.52
Dynein-mediated cargo transport in vivo. A switch controls travel distance. J Cell Biol (2000) 2.51
Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Science (2014) 2.35
Genetic analysis of the cytoplasmic dynein subunit families. PLoS Genet (2006) 2.35
Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J (2001) 2.34
A role for cytoplasmic dynein and LIS1 in directed cell movement. J Cell Biol (2003) 2.23
A cytoplasmic dynein tail mutation impairs motor processivity. Nat Cell Biol (2010) 2.20
Microtubule binding by dynactin is required for microtubule organization but not cargo transport. J Cell Biol (2007) 2.17
A primary role for Golgi positioning in directed secretion, cell polarity, and wound healing. Mol Biol Cell (2009) 2.05
Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol Biol Cell (2003) 2.04
Regulation of the processivity and intracellular localization of Saccharomyces cerevisiae dynein by dynactin. Proc Natl Acad Sci U S A (2009) 1.99
Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control. Mol Biol Cell (2005) 1.98
Dynein achieves processive motion using both stochastic and coordinated stepping. Nat Struct Mol Biol (2012) 1.98
A dynein loading zone for retrograde endosome motility at microtubule plus-ends. EMBO J (2006) 1.96
Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B. J Cell Biol (2010) 1.94
Walking the walk: how kinesin and dynein coordinate their steps. Curr Opin Cell Biol (2009) 1.94
Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependent. Mol Biol Cell (2003) 1.85
The yeast class V myosins, Myo2p and Myo4p, are nonprocessive actin-based motors. J Cell Biol (2001) 1.72
A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. J Cell Biol (2002) 1.72
Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol (2002) 1.70
Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function. Biophys J (2008) 1.70
Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment. Mol Biol Cell (2007) 1.67
Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc Natl Acad Sci U S A (2008) 1.65
Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J (2003) 1.65
Detection of fractional steps in cargo movement by the collective operation of kinesin-1 motors. Proc Natl Acad Sci U S A (2007) 1.64
Multiple modes of cytoplasmic dynein regulation. Nat Cell Biol (2012) 1.59
Dynactin is required for transport initiation from the distal axon. Neuron (2012) 1.59
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet (2010) 1.59
Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly. Mol Biol Cell (2005) 1.58
Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport. J Neurosci (2009) 1.57
Axonal transport: cargo-specific mechanisms of motility and regulation. Neuron (2014) 1.55
Regulation of dynactin through the differential expression of p150Glued isoforms. J Biol Chem (2008) 1.54
The genetics of axonal transport and axonal transport disorders. PLoS Genet (2006) 1.49
Human cytomegalovirus labeled with green fluorescent protein for live analysis of intracellular particle movements. J Virol (2005) 1.49
Poleward transport of Eg5 by dynein-dynactin in Xenopus laevis egg extract spindles. J Cell Biol (2008) 1.49
Two kinesins transport cargo primarily via the action of one motor: implications for intracellular transport. Biophys J (2010) 1.49
Transient binding of dynein controls bidirectional long-range motility of early endosomes. Proc Natl Acad Sci U S A (2011) 1.46
Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment. Mol Biol Cell (2010) 1.46
In vitro reconstitution of a highly processive recombinant human dynein complex. EMBO J (2014) 1.45
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures. Mol Biol Cell (2012) 1.44
Mitochondrial transport and docking in axons. Exp Neurol (2009) 1.41
The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Dev Cell (2005) 1.39
Dynactin is required to maintain nuclear position within postmitotic Drosophila photoreceptor neurons. Development (2004) 1.38
Autophagy in neurodegeneration and development. Biochim Biophys Acta (2008) 1.38
The G59S mutation in p150(glued) causes dysfunction of dynactin in mice. J Neurosci (2007) 1.36
Multiple ATP-hydrolyzing sites that potentially function in cytoplasmic dynein. Proc Natl Acad Sci U S A (2004) 1.32
Asymmetry of early endosome distribution in C. elegans embryos. PLoS One (2007) 1.32
Exploitation of microtubule cytoskeleton and dynein during parvoviral traffic toward the nucleus. J Virol (2003) 1.31
Adenovirus transport via direct interaction of cytoplasmic dynein with the viral capsid hexon subunit. Cell Host Microbe (2009) 1.30
Motor number controls cargo switching at actin-microtubule intersections in vitro. Curr Biol (2010) 1.30
Nudel modulates kinetochore association and function of cytoplasmic dynein in M phase. Mol Biol Cell (2007) 1.30
Tuning microtubule-based transport through filamentous MAPs: the problem of dynein. Traffic (2008) 1.29
Transcription factor NF-kappaB is transported to the nucleus via cytoplasmic dynein/dynactin motor complex in hippocampal neurons. PLoS One (2007) 1.26
Mutually exclusive cytoplasmic dynein regulation by NudE-Lis1 and dynactin. J Biol Chem (2011) 1.26
Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells. J Cell Biol (2008) 1.25
Ordered recruitment of dynactin to the microtubule plus-end is required for efficient initiation of retrograde axonal transport. J Neurosci (2013) 1.25
Subunit organization in cytoplasmic dynein subcomplexes. Protein Sci (2002) 1.24
Retracted Dynein, dynactin, and kinesin II's interaction with microtubules is regulated during bidirectional organelle transport. J Cell Biol (2000) 1.24
A mechanistic model for the organization of microtubule asters by motor and non-motor proteins in a mammalian mitotic extract. Mol Biol Cell (2004) 1.23
Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration. Proc Natl Acad Sci U S A (2009) 1.23
Dynactin function in mitotic spindle positioning. Traffic (2008) 1.22
Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol (2006) 1.22
A nonprocessive class V myosin drives cargo processively when a kinesin- related protein is a passenger. Curr Biol (2009) 1.21
Dynactin's pointed-end complex is a cargo-targeting module. Mol Biol Cell (2012) 1.20
High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport. J Cell Biol (2011) 1.19
Function of dynein in budding yeast: mitotic spindle positioning in a polarized cell. Cell Motil Cytoskeleton (2009) 1.19
Golgi positioning. Cold Spring Harb Perspect Biol (2011) 1.17
The p25 subunit of the dynactin complex is required for dynein-early endosome interaction. J Cell Biol (2011) 1.17
Golgin160 recruits the dynein motor to position the Golgi apparatus. Dev Cell (2012) 1.16
The herpesvirus VP1/2 protein is an effector of dynein-mediated capsid transport and neuroinvasion. Cell Host Microbe (2013) 1.15
Systematic dissection of dynein regulators in mitosis. J Cell Biol (2013) 1.15
Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor. PLoS Biol (2013) 1.15
Cell polarity as a regulator of cancer cell behavior plasticity. Annu Rev Cell Dev Biol (2012) 1.15
Reconstitution of the human cytoplasmic dynein complex. Proc Natl Acad Sci U S A (2012) 1.13
Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array. Mol Biol Cell (2011) 1.13
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
The gene for the intermediate chain subunit of cytoplasmic dynein is essential in Drosophila. Genetics (2002) 1.11
Cytoplasmic dynein nucleates microtubules to organize them into radial arrays in vivo. Mol Biol Cell (2004) 1.11
A Cdk5-dependent switch regulates Lis1/Ndel1/dynein-driven organelle transport in adult axons. J Neurosci (2011) 1.10
Recruitment of dynein to late endosomes and lysosomes through light intermediate chains. Mol Biol Cell (2010) 1.10
Carboxypeptidase E cytoplasmic tail-driven vesicle transport is key for activity-dependent secretion of peptide hormones. Mol Endocrinol (2008) 1.10
ER-to-Golgi transport visualized in living cells. Nature (1997) 10.24
Localization of cytoplasmic dynein to mitotic spindles and kinetochores. Nature (1990) 7.33
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol (1991) 5.02
Dynactin is required for microtubule anchoring at centrosomes. J Cell Biol (1999) 4.19
Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin. J Cell Biol (1994) 3.74
Opposing motor activities are required for the organization of the mammalian mitotic spindle pole. J Cell Biol (1996) 3.15
Microtubule- and motor-dependent fusion in vitro between apical and basolateral endocytic vesicles from MDCK cells. Cell (1990) 3.07
A vertebrate actin-related protein is a component of a multisubunit complex involved in microtubule-based vesicle motility. Nature (1992) 2.81
Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol Biol Cell (1999) 2.72
Evidence for a role of CLIP-170 in the establishment of metaphase chromosome alignment. J Cell Biol (1998) 2.16
Molecular requirements for bi-directional movement of phagosomes along microtubules. J Cell Biol (1997) 2.13
Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. J Cell Biol (1999) 2.06
WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol (1993) 2.04
Differential localization and sequence analysis of capping protein beta-subunit isoforms of vertebrates. J Cell Biol (1994) 2.00
Polarity and nucleation of microtubules in polarized epithelial cells. Cell Motil Cytoskeleton (1995) 1.87
Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting. Cell (1980) 1.83
Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. J Biol Chem (1998) 1.81
Apical plasma membrane proteins and endolyn-78 travel through a subapical compartment in polarized WIF-B hepatocytes. J Cell Biol (1998) 1.54
Purification of dynactin and dynein from brain tissue. Methods Enzymol (1998) 1.46
Membrane motors. Curr Opin Cell Biol (1999) 1.43
Immunolocalization of cytoplasmic dynein and dynactin subunits in cultured macrophages: enrichment on early endocytic organelles. J Cell Sci (2001) 1.37
Characterization of DLC-A and DLC-B, two families of cytoplasmic dynein light chain subunits. Mol Biol Cell (1994) 1.33
Actin-related proteins. Annu Rev Cell Dev Biol (1999) 1.29
Role for microtubules in centrosome doubling in Chinese hamster ovary cells. Cell Motil Cytoskeleton (1999) 1.23
Self-regulated polymerization of the actin-related protein Arp1. Curr Biol (1999) 1.16
In vitro translocation of organelles along microtubules. Cell (1985) 1.12
Real time imaging reveals a peroxisomal reticulum in living cells. J Cell Sci (2000) 1.10
Membrane traffic in neurons and peptide-secreting cells. Cold Spring Harb Symp Quant Biol (1983) 1.06
The mechanism and regulation of fast axonal transport. Trends Neurosci (1989) 1.04
Dynein and dynactin colocalize with AQP2 water channels in intracellular vesicles from kidney collecting duct. Am J Physiol (1998) 0.99
Fast axonal transport of foreign synaptic vesicles in squid axoplasm. J Cell Biol (1985) 0.98