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S A Spector

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. J Virol 1994 5.36
2 Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group. Ann Neurol 1997 4.17
3 Oral ganciclovir as maintenance treatment for cytomegalovirus retinitis in patients with AIDS. Syntex Cooperative Oral Ganciclovir Study Group. N Engl J Med 1995 3.28
4 Detection of human cytomegalovirus in clinical specimens by DNA-DNA hybridization. J Infect Dis 1984 3.10
5 Human immunodeficiency virus infection of human-PBL-SCID mice. Science 1991 2.77
6 Combination therapy with efavirenz, nelfinavir, and nucleoside reverse-transcriptase inhibitors in children infected with human immunodeficiency virus type 1. Pediatric AIDS Clinical Trials Group 382 Team. N Engl J Med 1999 2.67
7 Human immunodeficiency virus pseudotypes with expanded cellular and species tropism. J Virol 1990 2.66
8 A pilot study of low-dose zidovudine in human immunodeficiency virus infection. N Engl J Med 1990 2.48
9 Evidence for early central nervous system involvement in the acquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infections. Studies with neuropsychologic testing and magnetic resonance imaging. Ann Intern Med 1987 2.46
10 Prevalence of psychiatric disorders among men infected with human immunodeficiency virus. A controlled study. Arch Gen Psychiatry 1988 2.36
11 Utility of urine and leukocyte cultures and plasma DNA polymerase chain reaction for identification of AIDS patients at risk for developing human cytomegalovirus disease. J Infect Dis 1997 2.31
12 A health status questionnaire using 30 items from the Medical Outcomes Study. Preliminary validation in persons with early HIV infection. Med Care 1991 2.30
13 Combination therapy with zidovudine and dideoxycytidine in patients with advanced human immunodeficiency virus infection. A phase I/II study. Ann Intern Med 1992 2.19
14 High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes. J Infect Dis 1997 2.14
15 Localization of human cytomegalovirus in peripheral blood leukocytes by in situ hybridization. J Infect Dis 1990 2.08
16 Pharmacokinetics of nevirapine in human immunodeficiency virus type 1-infected pregnant women and their neonates. Pediatric AIDS Clinical Trials Group Protocol 250 Team. J Infect Dis 1998 2.08
17 Unrestricted replication of human cytomegalovirus in hydrocortisone-treated macrophages. J Virol 1991 2.07
18 Monitoring plasma HIV-1 RNA levels in addition to CD4+ lymphocyte count improves assessment of antiretroviral therapeutic response. ACTG 241 Protocol Virology Substudy Team. Ann Intern Med 1997 2.06
19 Early diagnosis of human cytomegalovirus disease in transplant recipients by DNA amplification in plasma. Transplantation 1993 2.02
20 Predictive value of quantitative plasma HIV RNA and CD4+ lymphocyte count in HIV-infected infants and children. JAMA 1998 2.00
21 High-dose nevirapine: safety, pharmacokinetics, and antiviral effect in patients with human immunodeficiency virus infection. J Infect Dis 1995 1.97
22 A cross-sectional comparison of persons with syncytium- and non-syncytium-inducing human immunodeficiency virus. J Infect Dis 1993 1.93
23 A randomized trial of three antipneumocystis agents in patients with advanced human immunodeficiency virus infection. NIAID AIDS Clinical Trials Group. N Engl J Med 1995 1.89
24 Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology 2000 1.88
25 Enzymatic amplification of human cytomegalovirus sequences by polymerase chain reaction. J Clin Microbiol 1989 1.81
26 Virologic characterization of primary human immunodeficiency virus type 1 infection in a health care worker following needlestick injury. J Infect Dis 1995 1.79
27 Phase I/II evaluation of nevirapine alone and in combination with zidovudine for infection with human immunodeficiency virus. J Acquir Immune Defic Syndr Hum Retrovirol 1995 1.55
28 Antibody to a synthetic oligopeptide in subjects at risk for human immunodeficiency virus infection. J Clin Microbiol 1987 1.49
29 Mutations in human cytomegalovirus UL97 gene confer clinical resistance to ganciclovir and can be detected directly in patient plasma. J Clin Invest 1995 1.47
30 Comparison of quantitative and qualitative PCR assays for cytomegalovirus DNA in plasma. J Clin Microbiol 2001 1.45
31 Multicenter trial of Towne strain attenuated virus vaccine in seronegative renal transplant recipients. Transplantation 1994 1.37
32 Rapid antiviral DNA-DNA hybridization assay for human cytomegalovirus. J Virol Methods 1990 1.36
33 Muscle architecture and force-velocity characteristics of cat soleus and medial gastrocnemius: implications for motor control. J Neurophysiol 1980 1.36
34 Diagnosis of human cytomegalovirus central nervous system disease in AIDS patients by DNA amplification from cerebrospinal fluid. J Infect Dis 1992 1.31
35 Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance. Arch Ophthalmol 1998 1.29
36 Adenovirus type 7b in a children's hospital. J Infect Dis 1983 1.26
37 Malassezia fungemia in neonates and adults: complication of hyperalimentation. Rev Infect Dis 1988 1.25
38 Ganciclovir treatment of symptomatic congenital cytomegalovirus infection: results of a phase II study. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. J Infect Dis 1997 1.24
39 Single-dose pharmacokinetics of acyclovir. Antimicrob Agents Chemother 1981 1.23
40 Identification of multiple cytomegalovirus strains in homosexual men with acquired immunodeficiency syndrome. J Infect Dis 1984 1.22
41 Ganciclovir for the treatment and suppression of serious infections caused by cytomegalovirus. Am J Med 1987 1.22
42 Summary of the II International Symposium on Cytomegalovirus. Antiviral Res 1998 1.21
43 Longitudinal study of cytomegalovirus retinitis in acquired immune deficiency syndrome. Ophthalmology 1990 1.21
44 Detecting human immunodeficiency virus RNA in peripheral blood mononuclear cells by nucleic acid hybridization. J Infect Dis 1987 1.20
45 Use of changes in plasma levels of human immunodeficiency virus type 1 RNA to assess the clinical benefit of antiretroviral therapy. J Infect Dis 1998 1.20
46 A randomized study of combined zidovudine-lamivudine versus didanosine monotherapy in children with symptomatic therapy-naive HIV-1 infection. The Pediatric AIDS Clinical Trials Group Protocol 300 Study Team. J Pediatr 1998 1.18
47 Predictors of virologic and clinical outcomes in HIV-1-infected patients receiving concurrent treatment with indinavir, zidovudine, and lamivudine. AIDS Clinical Trials Group Protocol 320. Ann Intern Med 2001 1.18
48 Randomized trials of dichlorphenamide in the periodic paralyses. Working Group on Periodic Paralysis. Ann Neurol 2000 1.17
49 Architectural alterations of rat hind-limb skeletal muscles immobilized at different lengths. Exp Neurol 1982 1.15
50 Lack of autologous neutralizing antibody to human immunodeficiency virus type 1 (HIV-1) and macrophage tropism are associated with mother-to-infant transmission. J Infect Dis 1999 1.13
51 Alternating and intermittent regimens of zidovudine and dideoxycytidine in patients with AIDS or AIDS-related complex. Ann Intern Med 1993 1.11
52 Treatment of human immunodeficiency virus 1-infected infants and children with the protease inhibitor nelfinavir mesylate. Clin Infect Dis 1999 1.10
53 Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. Arch Intern Med 1998 1.09
54 Human immunodeficiency virus DNA is present in a high percentage of CD4+ lymphocytes of seropositive individuals. J Infect Dis 1991 1.09
55 Transmission of cytomegalovirus among infants in hospital documented by restriction-endonuclease-digestion analyses. Lancet 1983 1.08
56 The effects of cytomegalovirus on human immunodeficiency virus replication in brain-derived cells correlate with permissiveness of the cells for each virus. J Virol 1994 1.08
57 Cytomegaloviruria in older infants in intensive care nurseries. J Pediatr 1979 1.06
58 Poor outcome is associated with delayed tuberculosis diagnosis in HIV-infected children in Baja California, Mexico. Int J Tuberc Lung Dis 2008 1.06
59 Human cytomegalovirus-mediated enhancement of human immunodeficiency virus type-1 production in monocyte-derived macrophages. Virology 1994 1.05
60 Effects of acyclovir combined with other antiviral agents on human cytomegalovirus. Am J Med 1982 1.05
61 The use of DNA probes in studies of human cytomegalovirus. Clin Chem 1985 1.04
62 Numerous length polymorphisms at short tandem repeats in human cytomegalovirus. J Virol 1999 1.03
63 Toxicity of combined ganciclovir and zidovudine for cytomegalovirus disease associated with AIDS. An AIDS Clinical Trials Group Study. Ann Intern Med 1990 1.03
64 Clinical significance of human immunodeficiency virus type 1 phenotypes in infected children. J Infect Dis 1994 1.01
65 The oncogenic potential of human cytomegalovirus. Prog Med Virol 1984 1.01
66 Appearance of autologous neutralizing antibody correlates with reduction in virus load and phenotype switch during primary infection with human immunodeficiency virus type 1. J Infect Dis 1997 1.01
67 Lymphoproliferative responses to recombinant HIV-1 envelope antigens in neonates and infants receiving gp120 vaccines. AIDS Clinical Trial Group 230 Collaborators. J Infect Dis 2000 1.01
68 Human immunodeficiency virus type 1 (HIV-1) gp120-specific antibodies in neonates receiving an HIV-1 recombinant gp120 vaccine. J Infect Dis 2001 1.01
69 Chronic administration of nevirapine during pregnancy: impact of pregnancy on pharmacokinetics. HIV Med 2008 0.99
70 Incidence of AIDS dementia in a two-year follow-up of AIDS and ARC patients on an initial phase II AZT placebo-controlled study: San Diego cohort. J Neuropsychiatry Clin Neurosci 1992 0.99
71 Trophic effects on the contractile and histochemical properties of rat soleus muscle. J Neurosci 1985 0.98
72 Quality of life in a placebo-controlled trial of zidovudine in patients with AIDS and AIDS-related complex. J Acquir Immune Defic Syndr 1990 0.98
73 Cytomegalovirus (CMV) retinitis activity is accurately reflected by the presence and level of CMV DNA in aqueous humor and vitreous. J Infect Dis 1999 0.97
74 HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand. AIDS 1997 0.97
75 Transmission of herpes simplex virus type 1 to a newborn infant during endotracheal suctioning for meconium aspiration. Pediatr Infect Dis 1984 0.97
76 Quantitation of human cytomegalovirus (HCMV) DNA in cerebrospinal fluid by competitive PCR in AIDS patients with different HCMV central nervous system diseases. Scand J Infect Dis 1995 0.97
77 Human immunodeficiency virus type 1 infection of human placenta: potential route for fetal infection. J Virol 1991 0.96
78 Summary of the International Consensus Symposium on Advances in the Diagnosis, Treatment and Prophylaxis and Cytomegalovirus Infection. Antiviral Res 1996 0.96
79 Study of the usefulness of clinical and hematologic findings in the diagnosis of neonatal bacterial infections. Clin Pediatr (Phila) 1981 0.95
80 Impairment in T-lymphocyte responses during early infection with the human immunodeficiency virus. J Clin Immunol 1989 0.95
81 Pharmacokinetics and pharmacodynamics of efavirenz and nelfinavir in HIV-infected children participating in an area-under-the-curve controlled trial. Clin Pharmacol Ther 2007 0.95
82 Neonatal acyclovir pharmacokinetics in patients with herpes virus infections. Am J Med 1982 0.95
83 Resistance to AZT and ddC during long-term combination therapy in patients with advanced infection with human immunodeficiency virus. J Acquir Immune Defic Syndr 1994 0.94
84 Human cord blood mononuclear cells are preferentially infected by non-syncytium-inducing, macrophage-tropic human immunodeficiency virus type 1 isolates. J Clin Microbiol 1995 0.94
85 Human immunodeficiency virus type 1 induction mediated by genistein is linked to cell cycle arrest in G2. J Virol 1998 0.94
86 A randomized trial of the activity and safety of Ro 24-7429 (Tat antagonist) versus nucleoside for human immunodeficiency virus infection. The AIDS Clinical Trials Group 213 Team. J Infect Dis 1995 0.94
87 Rapid determination of molecular relatedness of isolates of human cytomegalovirus. J Infect Dis 1985 0.93
88 Human cytomegalovirus inhibits human immunodeficiency virus replication in cells productively infected by both viruses. J Virol 1991 0.93
89 Low rate of CMV end-organ disease in HIV-infected patients despite low CD4+ cell counts and CMV viremia: results of ACTG protocol A5030. HIV Clin Trials 2009 0.93
90 The safety of discontinuation of maintenance therapy for cytomegalovirus (CMV) retinitis and incidence of immune recovery uveitis following potent antiretroviral therapy. HIV Clin Trials 2005 0.92
91 Plesiomonas shigelloides septicemia and meningitis in a newborn. Pediatr Infect Dis J 1988 0.91
92 Cotransduction of nondividing cells using lentiviral vectors. Gene Ther 2000 0.91
93 Development and significance of zidovudine resistance in children infected with human immunodeficiency virus. J Pediatr 1993 0.91
94 Detection of human cytomegalovirus mutations associated with ganciclovir resistance in cerebrospinal fluid of AIDS patients with central nervous system disease. Antimicrob Agents Chemother 1995 0.91
95 Resolution of HIV-associated nephrotic syndrome with highly active antiretroviral therapy delivered by gastrostomy tube. Pediatrics 1999 0.91
96 Histochemical and physiological properties of cat motor units after self-and cross-reinnervation. J Physiol 1982 0.90
97 Impact of Pneumocystis carinii and cytomegalovirus on the course and outcome of atypical pneumonia in advanced human immunodeficiency virus disease. J Infect Dis 1992 0.90
98 Length of incubation time for human immunodeficiency virus cultures. J Clin Microbiol 1995 0.89
99 Polyradiculopathy associated with ganciclovir-resistant cytomegalovirus in an AIDS patient: phenotypic and genotypic characterization of sequential virus isolates. J Infect Dis 1996 0.89
100 Effects of elimination of activity on contractile and histochemical properties of rat soleus muscle. J Neurosci 1985 0.88
101 Contractile properties of rat hind limb muscles immobilized at different lengths. Exp Neurol 1982 0.87
102 Replication of macrophage-tropic and T-cell-tropic strains of human immunodeficiency virus type 1 is augmented by macrophage-endothelial cell contact. J Virol 1995 0.87
103 Molecular epidemiology of cytomegalovirus infections in premature twin infants and their mother. Pediatr Infect Dis 1983 0.87
104 Associations of CCR5, CCR2, and stromal cell-derived factor 1 genotypes with human immunodeficiency virus disease progression in patients receiving nucleoside therapy. J Infect Dis 2001 0.87
105 Prevalence of tremor and Parkinson's disease. Parkinsonism Relat Disord 1996 0.87
106 Cytomegalovirus infection and bronchopulmonary dysplasia in premature infants. Am J Dis Child 1987 0.86
107 Human cytomegalovirus-associated immunosuppression is mediated through interferon-alpha. Blood 1997 0.86
108 Malasezzia furfur sepsis in neonates. J Pediatr 1985 0.85
109 Differential effects of human cytomegalovirus on integrated and unintegrated human immunodeficiency virus sequences. J Virol 1995 0.85
110 Deterioration of detectable human immunodeficiency virus serum p24 antigen in samples stored for batch testing. J Clin Microbiol 1997 0.85
111 Lactoferrin inhibits HIV-1 replication in vitro and exhibits synergy when combined with zidovudine. AIDS 1999 0.84
112 Is resistance of a muscle to fatigue controlled by its motoneurones? Nature 1980 0.84
113 Virologic and immunologic response to nucleoside reverse-transcriptase inhibitor therapy among human immunodeficiency virus-infected infants and children. J Infect Dis 1999 0.84
114 Functional status and well-being in a placebo-controlled trial of zidovudine in early symptomatic HIV infection. J Acquir Immune Defic Syndr 1993 0.84
115 The CCR5Delta32 allele slows disease progression of human immunodeficiency virus-1-infected children receiving antiretroviral treatment. J Infect Dis 2000 0.83
116 Performance of rapid HIV testing using Determine HIV-1/2 for the diagnosis of HIV infection during pregnancy in Tijuana, Baja California, Mexico. Int J STD AIDS 2007 0.83
117 Fidelity of whole-genome amplification of blood spot DNA for HLA typing and SNP analyses. Clin Genet 2007 0.83
118 The effect of zidovudine treatment on serum neopterin and beta 2-microglobulin levels in mildly symptomatic, HIV type 1 seropositive individuals. J Acquir Immune Defic Syndr 1992 0.83
119 Population pharmacokinetics of dapsone in children with human immunodeficiency virus infection. Clin Pharmacol Ther 2001 0.83
120 Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid of infected children. J Infect Dis 1996 0.82
121 Gastrostomy tube insertion for improvement of adherence to highly active antiretroviral therapy in pediatric patients with human immunodeficiency virus. Pediatrics 2000 0.82
122 Impaired hepatocyte glucose transport protein (GLUT2) internalization in chronic pancreatitis. Pancreas 2001 0.82
123 Treatment of herpes virus infections in immunocompromised patients with acyclovir by continuous intravenous infusion. Am J Med 1982 0.81
124 Generation of human cytomegalovirus-specific cytotoxic T-lymphocytes in a short-term culture. J Immunol Methods 1988 0.81
125 The evolution of lymphadenopathy and hypergammaglobulinemia are evidence for early and sustained polyclonal B lymphocyte activation during human immunodeficiency virus infection. J Infect Dis 1991 0.81
126 Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: preclinical studies. Gene Ther 1998 0.81
127 Effect of HIV genotypic drug resistance testing on the management and clinical course of HIV-infected children and adolescents. Int J STD AIDS 2013 0.80
128 Inhibition of human cytomegalovirus by trifluorothymidine. Antimicrob Agents Chemother 1983 0.80
129 Treatment of bacterial meningitis with once daily ceftriaxone therapy. J Antimicrob Chemother 1988 0.79
130 Zidovudine pharmacokinetics in premature infants exposed to human immunodeficiency virus. Antimicrob Agents Chemother 1998 0.79
131 Applications of immunogold-silver enhancement: testing of monoclonal antibodies and detection of human cytomegalovirus in histologic specimens. Am J Anat 1989 0.79
132 Overexpression of hepatic pancreatic polypeptide receptors in chronic pancreatitis. J Surg Res 1998 0.79
133 Human immunodeficiency virus-associated neurobehavioural disorder. J R Coll Physicians Lond 1988 0.79
134 Fatal echovirus type 11 infections. Am J Dis Child 1981 0.79
135 Human immunodeficiency virus type 1 infection of neonatal severe combined immunodeficient mice xenografted with human cord blood cells. AIDS Res Hum Retroviruses 1994 0.79
136 Optimization of quantitative culture assay for human immunodeficiency virus from plasma. Plasma Viremia Group Laboratories of the AIDS Clinical Trials Group (National Institute of Allergy and Infectious Diseases). J Clin Microbiol 1994 0.79
137 Nosocomial cytomegalovirus infections within two hospitals caring for infants and children. J Infect Dis 1987 0.78
138 Assays for antiviral drug resistance. Antiviral Res 1995 0.78
139 Peripheral nerve function in persons with asymptomatic or minimally symptomatic HIV disease: absence of zidovudine neurotoxicity. J Acquir Immune Defic Syndr 1991 0.78
140 Dysregulation of cytokine expression in monocytes from HIV-positive individuals. J Leukoc Biol 1994 0.78
141 Disease patterns and survival after acquired immunodeficiency syndrome diagnosis in human immunodeficiency virus-infected children. Pediatr Infect Dis J 1996 0.78
142 Molecular analysis of the differential restriction of human immunodeficiency virus type 1 replication in neuronal cell lines. J Gen Virol 1997 0.78
143 Electrophysiologic and histologic studies in clinically unaffected muscles of patients with prior paralytic poliomyelitis. Muscle Nerve 1996 0.77
144 Model for microneurovascular muscle transplantation in the dog. Plast Reconstr Surg 1986 0.77
145 Combination therapy with recombinant human soluble CD4-immunoglobulin G and zidovudine in patients with HIV infection: a phase I study. J Acquir Immune Defic Syndr Hum Retrovirol 1995 0.77
146 Toxicity and efficacy of daily vs. weekly dapsone for prevention of Pneumocystis carinii pneumonia in children infected with human immunodeficiency virus. ACTG 179 Study Team. AIDS Clinical Trials Group. Pediatr Infect Dis J 1999 0.77
147 A model system for human cytomegalovirus-mediated modulation of human immunodeficiency virus type 1 long terminal repeat activity in brain cells. J Virol 1997 0.77
148 Recurrent herpes simplex in a neonate. Pediatr Infect Dis 1986 0.77
149 Oral ganciclovir in children: pharmacokinetics, safety, tolerance, and antiviral effects. The Pediatric AIDS Clinical Trials Group. J Infect Dis 2000 0.77
150 Inhibition of human cytomegalovirus by combined acyclovir and vidarabine. Antimicrob Agents Chemother 1985 0.77
151 Search for cytomegalovirus in the postmortem brains of schizophrenic patients using the polymerase chain reaction. Arch Gen Psychiatry 1992 0.76
152 Low prevalence of HIV-1 proviral DNA in peripheral blood monocytes and dendritic cells from HIV-1-infected individuals. AIDS 1995 0.76
153 Prevalence of primary HIV-1 drug resistance in pregnant women and in newly diagnosed adults at Tijuana General Hospital, Baja California, Mexico. Int J STD AIDS 2007 0.76
154 Pediatrics: Hemophilus influenzae Type b Immunization. West J Med 1986 0.75
155 Chronic cough in infants younger than three months. West J Med 1982 0.75
156 Transmission of cytomegalovirus from husband to wife. J Infect Dis 1986 0.75
157 Protean manifestations of perinatal enterovirus infections. West J Med 1983 0.75
158 Detection and quantification of human cytomegalovirus (CMV) as a marker for development of CMV disease and survival in patients with AIDS. Antivir Ther 1997 0.75
159 Pediatrics-epitomes of progress: treatment of disseminated herpes infections in newborns and infants. West J Med 1982 0.75
160 Fever and leukopenia in a 2-year-old. West J Med 1983 0.75
161 Absence of infectious retinitis after injection of human cytomegalovirus into rabbit eyes. J Infect Dis 1995 0.75
162 Anosmia and mouse killing by rats: a nonolfactory role for the olfactory bulbs. J Comp Physiol Psychol 1972 0.75
163 Pediatric human immunodeficiency virus infection in a low seroprevalence area. Pediatr Infect Dis J 1993 0.75
164 HIV-1 neurocognitive disorders and chemokine receptors. AIDS 1997 0.75
165 Mission to Brazil: a surgical perspective. Bull Am Coll Surg 1998 0.75
166 The impact of concomitant viral pathogens on the course of Pneumocystis carinii pneumonia. J Protozool 1992 0.75
167 Reinnervation in clinically unaffected muscles of patients with prior paralytic poliomyelitis. Correlation between macroelectromyography and histology. Ann N Y Acad Sci 1995 0.75
168 Human immunodeficiency virus type 1 phenotypes in children with advanced disease treated with long-term zalcitabine. J Infect Dis 1998 0.75