Published in Clin Cancer Res on December 01, 1999
Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward? Cancer Biol Ther (2008) 1.74
Anti-oxidative stress response genes: bioinformatic analysis of their expression and relevance in multiple cancers. Oncotarget (2013) 0.94
NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols. J Transl Med (2008) 0.85
Novel biomarker panel predicts prognosis in human papillomavirus-negative oropharyngeal cancer: an analysis of the TAX 324 trial. Cancer (2011) 0.82
Glutathione S-transferase M1 and T1 polymorphism and response to neoadjuvant chemotherapy (CAF) in breast cancer patients. Surg Today (2011) 0.81
Anomalous altered expressions of downstream gene-targets in TP53-miRNA pathways in head and neck cancer. Sci Rep (2014) 0.80
Markers of chemoradiation resistance in patients with locally advanced head and neck squamous cell carcinoma, treated by intra-arterial carboplatin and concurrent radiation. Acta Otorhinolaryngol Ital (2007) 0.80
p53 expression and resistance against paclitaxel in patients with metastatic breast cancer. J Cancer Res Clin Oncol (2003) 0.80
Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy. PLoS One (2013) 0.76
Predictive value of thymidylate synthase for the prognosis and survival of lung adenocarcinoma patients. Oncol Lett (2014) 0.75
GTSP1 expression in non-smoker and non-drinker patients with squamous cell carcinoma of the head and neck. PLoS One (2017) 0.75
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature (1999) 12.95
Nested retrotransposons in the intergenic regions of the maize genome. Science (1996) 12.95
Comparison of vignettes, standardized patients, and chart abstraction: a prospective validation study of 3 methods for measuring quality. JAMA (2000) 10.91
Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models. Acc Chem Res (2000) 10.78
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med (2000) 8.89
Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer: phase III randomized Intergroup study 0099. J Clin Oncol (1998) 7.26
Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids. Nature (1992) 7.02
BRCA1 testing in families with hereditary breast-ovarian cancer. A prospective study of patient decision making and outcomes. JAMA (1996) 5.95
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother (2001) 5.23
Comparative genome mapping of Sorghum and maize. Genetics (1992) 5.14
Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease. Proc Natl Acad Sci U S A (1997) 4.92
Antibody response in individuals infected with avian influenza A (H5N1) viruses and detection of anti-H5 antibody among household and social contacts. J Infect Dis (1999) 4.67
Molecular mechanisms of drug resistance. J Pathol (2005) 4.60
Case-control study of risk factors for avian influenza A (H5N1) disease, Hong Kong, 1997. J Infect Dis (1999) 4.59
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. J Neurochem (2001) 4.45
Single vs weekly courses of antenatal corticosteroids for women at risk of preterm delivery: A randomized controlled trial. JAMA (2001) 4.30
Assessing the use of medications in the elderly: methods and initial experience in the Cardiovascular Health Study. The Cardiovascular Health Study Collaborative Research Group. J Clin Epidemiol (1992) 4.11
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med (1997) 4.10
Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families. Proc Natl Acad Sci U S A (1988) 4.02
Appropriateness of the decision to transfer nursing facility residents to the hospital. J Am Geriatr Soc (2000) 3.99
How valid are mammography self-reports? Am J Public Health (1990) 3.86
How well does chart abstraction measure quality? A prospective comparison of standardized patients with the medical record. Am J Med (2000) 3.70
Psychological and behavioral implications of abnormal mammograms. Ann Intern Med (1991) 3.40
Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med (1995) 3.31
Psychological side effects of breast cancer screening. Health Psychol (1991) 3.30
Phospholipid:diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants. Proc Natl Acad Sci U S A (2000) 3.22
Factors associated with repeat adherence to breast cancer screening. Prev Med (1990) 3.01
Influence of PAX6 gene dosage on development: overexpression causes severe eye abnormalities. Cell (1996) 3.01
Somnolence after prophylactic cranial irradiation in children with acute lymphoblastic leukaemia. Br Med J (1973) 2.94
BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics. Hum Mol Genet (2001) 2.76
Methanogenesis in a Thermophilic (58 degrees C) Anaerobic Digestor: Methanothrix sp. as an Important Aceticlastic Methanogen. Appl Environ Microbiol (1984) 2.69
Modern management of spinal tuberculosis. Neurosurgery (1995) 2.55
The logistic modeling of sensitivity, specificity, and predictive value of a diagnostic test. J Clin Epidemiol (1992) 2.52
Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N Engl J Med (1996) 2.49
Survival and human papillomavirus in oropharynx cancer in TAX 324: a subset analysis from an international phase III trial. Ann Oncol (2011) 2.47
Are nonspecific practice guidelines potentially harmful? A randomized comparison of the effect of nonspecific versus specific guidelines on physician decision making. Health Serv Res (2000) 2.45
Markers of circulating tumour cells in the peripheral blood of patients with melanoma correlate with disease recurrence and progression. Br J Dermatol (2012) 2.31
High resolution microendoscopy for classification of colorectal polyps. Endoscopy (2013) 2.29
Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding. EMBO J (1999) 2.28
Measuring compliance with preventive care guidelines: standardized patients, clinical vignettes, and the medical record. J Gen Intern Med (2000) 2.21
Three-dimensional visualization of tegument/capsid interactions in the intact human cytomegalovirus. Virology (1999) 2.20
Inferences on the genome structure of progenitor maize through comparative analysis of rice, maize and the domesticated panicoids. Genetics (1999) 2.19
Which clinical anesthesia outcomes are both common and important to avoid? The perspective of a panel of expert anesthesiologists. Anesth Analg (1999) 2.12
Transverse carpal ligament: its effect on flexor tendon excursion, morphologic changes of the carpal canal, and on pinch and grip strengths after open carpal tunnel release. Plast Reconstr Surg (1997) 2.11
Mode of action of pectic enzymes. I. Purification and certain properties of tomato pectinesterase. Biochemistry (1968) 2.07
Psychological effects of ketamine in healthy volunteers. Phenomenological study. Br J Psychiatry (2006) 2.06
Genome-wide association scan for childhood caries implicates novel genes. J Dent Res (2011) 2.05
HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells. Oncogene (2007) 2.00
Chronic respiratory disease in a rural community. Lancet (1968) 2.00
Construction of an RFLP map in sorghum and comparative mapping in maize. Genome (1994) 1.97
Development and validation of a geriatrics attitudes scale for primary care residents. J Am Geriatr Soc (1998) 1.96
When is Helicobacter pylori infection acquired? Gut (1993) 1.94
Diet, physical activity, and colorectal cancer among Chinese in North America and China. J Natl Cancer Inst (1990) 1.92
Structure of the Drosophila DNA topoisomerase II gene. Nucleotide sequence and homology among topoisomerases II. J Mol Biol (1989) 1.89
Teaching social language to moderately handicapped students. J Appl Behav Anal (1986) 1.85
Pulmonary Kaposi's sarcoma in the acquired immune deficiency syndrome. Clinical, radiographic, and pathologic manifestations. Am J Med (1986) 1.85
An alpha-particle emitting antibody ([213Bi]J591) for radioimmunotherapy of prostate cancer. Cancer Res (2000) 1.85
Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis. Gastroenterology (1992) 1.79
Why do some women get regular mammograms? Am J Prev Med (1991) 1.78
A selective stain to detect the vagus nerve in the operation of vagotomy. Br J Surg (1969) 1.78
Cell cycle control genes in fission yeast and mammalian cells. Trends Genet (1988) 1.77
Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr Biol (1999) 1.75
The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine. J Biol Chem (1996) 1.72
Cannabinoid receptors CB1 and CB2: a characterization of expression and adenylate cyclase modulation within the immune system. Toxicol Appl Pharmacol (1997) 1.71
The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle. J Cell Sci (1999) 1.71
Assessing the clinical impact of prognostic factors: when is "statistically significant" clinically useful? Breast Cancer Res Treat (1998) 1.70
Analysis of metronidazole, clarithromycin and tetracycline resistance of Helicobacter pylori isolates from Korea. J Antimicrob Chemother (2001) 1.68
Familial uveal melanoma. Clinical observations on 56 patients. Arch Ophthalmol (1996) 1.67
Direct and indirect costs associated with the onset of seropositive rheumatoid arthritis. Western Consortium of Practicing Rheumatologists. J Rheumatol (2000) 1.67
Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics. Chem Res Toxicol (1993) 1.67
Proteomic patterns of nipple aspirate fluids obtained by SELDI-TOF: potential for new biomarkers to aid in the diagnosis of breast cancer. Dis Markers (2001) 1.67
Chemotherapy and radiation therapy before transhiatal esophagectomy for esophageal carcinoma. Ann Thorac Surg (1990) 1.66
c-FLIP inhibits chemotherapy-induced colorectal cancer cell death. Oncogene (2006) 1.66
Analysis of insulin-like growth factor I gene expression in malignancy: evidence for a paracrine role in human breast cancer. Mol Endocrinol (1989) 1.65
A call for participation in intergroup trials. Head Neck (1995) 1.65
Screening for lung cancer using low dose CT scanning. Thorax (2004) 1.64
Intestinal Obstruction by Gall-stones. Br Med J (1945) 1.64
Pediatricians' attitudes, beliefs, and practices regarding clinical practice guidelines: a national survey. Pediatrics (2000) 1.64
Familial and personal medical history of cancer and nervous system conditions among adults with glioma and controls. Am J Epidemiol (1997) 1.63
Cigarette smoking and cancer of bladder and lung. Br Med J (1976) 1.63
Keratocyte loss after corneal deepithelialization in primates and rabbits. Arch Ophthalmol (1994) 1.63
Improvement of thrombocytopenia due to hypersplenism after transjugular intrahepatic portosystemic shunt placement in cirrhotic patients. Am J Gastroenterol (1996) 1.61
Atrial fibrillation and mortality in an elderly population. Aust N Z J Med (1989) 1.61
Coronary angioscopy in patients with unstable angina pectoris. N Engl J Med (1986) 1.57
Cortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells. Oncogene (2006) 1.56
Ultrasonic spectral parameter characterization of apoptosis. Ultrasound Med Biol (2002) 1.55
Minimal cardiac effects in asymptomatic athyreotic patients chronically treated with thyrotropin-suppressive doses of L-thyroxine. J Clin Endocrinol Metab (1997) 1.54
Chest teleradiology in a teaching hospital emergency practice. AJR Am J Roentgenol (1997) 1.51
Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. Proc Natl Acad Sci U S A (1995) 1.51
Control of clonorchiasis by repeated praziquantel treatment and low diagnostic efficacy of sonography. Korean J Parasitol (1998) 1.51
Preliminary results of Radiation Therapy Oncology Group 97-03: a randomized phase ii trial of concurrent radiation and chemotherapy for advanced squamous cell carcinomas of the head and neck. J Clin Oncol (2004) 1.51
Breast screening practices among primary physicians: reality and potential. J Am Board Fam Pract (1990) 1.50
Sequences of taxol and cisplatin: a phase I and pharmacologic study. J Clin Oncol (1991) 1.49
The role of laparoscopy in preoperative staging of esophageal cancer. Surg Endosc (2000) 1.49
Spontaneous pneumothoraces in AIDS patients receiving aerosolized pentamidine. Chest (1988) 1.48
Uterine artery embolization for the treatment of uterine leiomyomata midterm results. J Vasc Interv Radiol (1999) 1.48
Cell cycle regulation of the G0/G1 transition in 5-fluorouracil-sensitive and -resistant human colon cancer cell lines. Cancer J (2001) 1.47