H Käyhty

Author PubWeight™ 158.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Efficacy of a pneumococcal conjugate vaccine against acute otitis media. N Engl J Med 2001 10.56
2 Haemophilus influenzae type b capsular polysaccharide vaccine in children: a double-blind field study of 100,000 vaccinees 3 months to 5 years of age in Finland. Pediatrics 1977 4.64
3 The protective level of serum antibodies to the capsular polysaccharide of Haemophilus influenzae type b. J Infect Dis 1983 4.05
4 Prevention of Hemophilus influenzae type b bacteremic infections with the capsular polysaccharide vaccine. N Engl J Med 1984 3.37
5 Clinical efficacy of meningococcus group A capsular polysaccharide vaccine in children three months to five years of age. N Engl J Med 1977 3.32
6 A randomized, prospective field trial of a conjugate vaccine in the protection of infants and young children against invasive Haemophilus influenzae type b disease. N Engl J Med 1990 2.90
7 Reduction of oropharyngeal carriage of Haemophilus influenzae type b (Hib) in children immunized with an Hib conjugate vaccine. J Infect Dis 1991 2.83
8 Polysaccharide vaccines of group A Neisseria meningtitidis and Haemophilus influenzae type b: a field trial in Finland. J Infect Dis 1977 2.79
9 Multicenter comparison of Neisseria meningitidis serogroup C anti-capsular polysaccharide antibody levels measured by a standardized enzyme-linked immunosorbent assay. J Clin Microbiol 1994 2.63
10 Efficacy of Haemophilus influenzae type b polysaccharide-diphtheria toxoid conjugate vaccine in infancy. N Engl J Med 1987 2.47
11 Natural development of antibodies to pneumococcal surface protein A, pneumococcal surface adhesin A, and pneumolysin in relation to pneumococcal carriage and acute otitis media. J Infect Dis 2000 2.11
12 An analytical model applied to a multicenter pneumococcal enzyme-linked immunosorbent assay study. J Clin Microbiol 2000 1.97
13 Effect of group-A meningococcal vaccine in army recruits in Finland. Lancet 1975 1.97
14 Avidity of IgG for Streptococcus pneumoniae type 6B and 23F polysaccharides in infants primed with pneumococcal conjugates and boosted with polysaccharide or conjugate vaccines. J Infect Dis 1998 1.76
15 Interlaboratory study evaluating quantitation of antibodies to Haemophilus influenzae type b polysaccharide by enzyme-linked immunosorbent assay. Clin Diagn Lab Immunol 1996 1.71
16 Antibody response to capsular polysaccharides of groups A and C neisseria meningitidis and Haemophilus influenzae type b during bacteremic disease. J Infect Dis 1981 1.65
17 Serum antibodies after vaccination with Haemophilus influenzae type b capsular polysaccharide and responses to reimmunization: no evidence of immunologic tolerance or memory. Pediatrics 1984 1.65
18 Randomised trial of the effect of co-administration with acellular pertussis DTP vaccine on immunogenicity of Haemophilus influenzae type b conjugate vaccine. Lancet 1997 1.62
19 Contribution of serotype-specific IgG concentration, IgG subclasses and relative antibody avidity to opsonophagocytic activity against Streptococcus pneumoniae. Clin Exp Immunol 1999 1.56
20 Cross-reactivity of antibodies to type 6B and 6A polysaccharides of Streptococcus pneumoniae, evoked by pneumococcal conjugate vaccines, in infants. J Infect Dis 2001 1.55
21 Serum antibodies to capsular polysaccharide vaccine of group A Neissera meningitidis followed for three years in infants and children. J Infect Dis 1980 1.53
22 Are the enzyme immunoassays for antibodies to pneumococcal capsular polysaccharides serotype specific? Clin Diagn Lab Immunol 2000 1.52
23 Antibody levels achieved in infants by course of Haemophilus influenzae type B polysaccharide/diphtheria toxoid conjugate vaccine. Lancet 1985 1.52
24 Natural development of antibodies to pneumococcal capsular polysaccharides depends on the serotype: association with pneumococcal carriage and acute otitis media in young children. J Infect Dis 2001 1.51
25 Increase in titers of antibodies to Mycoplasma pneumoniae in patients with purulent meningitis. J Infect Dis 1982 1.45
26 Differences in the avidity of antibodies evoked by four different pneumococcal conjugate vaccines in early childhood. Vaccine 1999 1.43
27 Isotype concentrations of human antibodies to Haemophilus influenzae type b polysaccharide (Hib) in young adults immunized with the polysaccharide as such or conjugated to a protein (diphtheria toxoid). J Immunol 1987 1.38
28 Concurrent administration of rhesus rotavirus tetravalent (RRV-TV) vaccine with pentavalent diphtheria-pertussis-tetanus-Haemophilus influenzae beta-inactivated polio and hepatitis B vaccines. Acta Paediatr 1999 1.38
29 Streptococcus pneumoniae capsular polysaccharide-diphtheria toxoid conjugate vaccine is immunogenic in early infancy and able to induce immunologic memory. Pediatr Infect Dis J 1998 1.37
30 Evaluation of two tetravalent (ACYW135) meningococcal vaccines in infants and small children: a clinical study comparing immunogenicity of O-acetyl-negative and O-acetyl-positive group C polysaccharides. Pediatrics 1985 1.34
31 Vaccination and the role of capsular polysaccharide antibody in prevention of recurrent meningococcal disease in late complement component-deficient individuals. J Infect Dis 1993 1.27
32 Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal surface adhesin a, pneumolysin, and pneumococcal surface protein a in children. J Infect Dis 2001 1.25
33 IgG subclass distribution of antibodies after vaccination of adults with pneumococcal conjugate vaccines. Vaccine 1999 1.24
34 Current state of pneumococcal vaccines. Scand J Immunol 2002 1.19
35 Comparison of counter-current immunoelectrophoresis, latex agglutination, and radioimmunoassay in detection of soluble capsular polysaccharide antigens of Haemophilus influenzae type b and Neisseria meningitidis of groups A or C. J Clin Pathol 1978 1.19
36 Anti-capsular polysaccharide antibodies reduce nasopharyngeal colonization by Haemophilus influenzae type b in infant rats. J Infect Dis 1993 1.16
37 Avidity and subclasses of IgG after immunization of infants with an 11-valent pneumococcal conjugate vaccine with or without aluminum adjuvant. J Infect Dis 2001 1.16
38 Anti-capsular polysaccharide antibody concentrations in saliva after immunization with Haemophilus influenzae type b conjugate vaccines. Pediatr Infect Dis J 1995 1.15
39 Isotype concentrations of human antibodies to group A meningococcal polysaccharide. J Immunol 1986 1.12
40 Human antibody responses to two conjugate vaccines of Haemophilus influenzae type B saccharides and diphtheria toxin. Scand J Immunol 1988 1.11
41 Genes involved in Haemophilus influenzae type b capsule expression are frequently amplified. J Infect Dis 1993 1.10
42 Pneumococcal conjugate vaccination in adults: circulating antibody secreting cell response and humoral antibody responses in saliva and in serum. Vaccine 1998 1.10
43 Pentavalent pneumococcal oligosaccharide conjugate vaccine PncCRM is well-tolerated and able to induce an antibody response in infants. Pediatr Infect Dis J 1996 1.10
44 Serum and salivary anti-capsular antibodies in infants and children immunized with the heptavalent pneumococcal conjugate vaccine. Pediatr Infect Dis J 2001 1.09
45 Vaccination with Haemophilus influenzae type b meningococcal protein conjugate vaccine reduces oropharyngeal carriage of Haemophilus influenzae type b among American Indian children. Pediatr Infect Dis J 1993 1.08
46 Assignment of immunoglobulin G1 and G2 concentrations to pneumococcal capsular polysaccharides 3, 6B, 14, 19F, and 23F in pneumococcal reference serum 89-SF. Clin Diagn Lab Immunol 1998 1.07
47 Radioimmunoassay of capsular polysaccharide antigens of groups A and C meningococci and Haemophilus influenzae type b in cerebrospinal fluid. J Clin Pathol 1977 1.07
48 Immune response to tetravalent meningococcal vaccine: opsonic and bactericidal functions of normal and properdin deficient sera. Eur J Clin Microbiol Infect Dis 1989 1.06
49 Immunogenicity in infants of a vaccine composed of Haemophilus influenzae type b capsular polysaccharide mixed with DPT or conjugated to diphtheria toxoid. J Infect Dis 1987 1.06
50 Distinct geographic distribution of subtypes of Haemophilus influenzae type b in Western Europe. J Infect Dis 1987 1.06
51 Are the opsonophagocytic activities of antibodies in infant sera measured by different pneumococcal phagocytosis assays comparable? Clin Diagn Lab Immunol 2001 1.05
52 Meningococcus group A vaccine in children three months to five years of age. Adverse reactions and immunogenicity related to endotoxin content and molecular weight of the polysaccharide. J Pediatr 1978 1.04
53 Antibody response to the pneumococcal proteins pneumococcal surface adhesin A and pneumolysin in children with acute otitis media. Pediatr Infect Dis J 2001 1.04
54 The infant rat model adapted to evaluate human sera for protective immunity to group B meningococci. Vaccine 1999 1.04
55 Synthetic trimer and tetramer of 3-beta-D-ribose-(1-1)-D-ribitol-5-phosphate conjugated to protein induce antibody responses to Haemophilus influenzae type b capsular polysaccharide in mice and monkeys. Infect Immun 1992 1.00
56 Monoclonal antibodies to the rough lipopolysaccharide of Neisseria meningitidis protect infant rats from meningococcal infection. J Infect Dis 1988 0.98
57 Vaccination of patients deficient in a late complement component with tetravalent meningococcal capsular polysaccharide vaccine. Clin Exp Immunol 1995 0.97
58 Neonatal immunization: response to Haemophilus influenzae type b-tetanus toxoid conjugate vaccine. Pediatrics 1995 0.97
59 Salivary anti-capsular antibodies in infants and children immunised with Streptococcus pneumoniae capsular polysaccharides conjugated to diphtheria or tetanus toxoid. Vaccine 2000 0.96
60 Tolerability and immunogenicity of an 11-valent pneumococcal conjugate vaccine in adults. Vaccine 2001 0.95
61 Clinical comparison of the Haemophilus influenzae type B polysaccharide-diphtheria toxoid and the oligosaccharide-CRM197 protein vaccines in infancy. Arch Pediatr Adolesc Med 1994 0.95
62 Comparison of passive hemagglutination, bactericidal activity, and radioimmunological methods in measuring antibody responses to Neisseria meningitidis group A capsular polysaccharide vaccine. J Clin Microbiol 1980 0.95
63 Immunological properties of recombinant porin of Haemophilus influenzae type b expressed in Bacillus subtilis. Infect Immun 1993 0.94
64 Salivary antibody response to vaccination with meningococcal A/C polysaccharide vaccine in previously vaccinated and unvaccinated Gambian children. Vaccine 2000 0.94
65 Circulating antibody secreting cell response to parenteral pneumococcal vaccines as an indicator of a salivary IgA antibody response. Vaccine 1998 0.94
66 Response to vaccination against different types of antigens in patients with chronic lymphocytic leukaemia. Br J Haematol 2001 0.94
67 Monoclonal antibodies specific to porin of Haemophilus influenzae type b: localization of their cognate epitopes and tests of their biological activities. Mol Microbiol 1992 0.94
68 Immunization with a pneumococcal capsular polysaccharide vaccine during pregnancy. Vaccine 1996 0.93
69 Comparison of a classical phagocytosis assay and a flow cytometry assay for assessment of the phagocytic capacity of sera from adults vaccinated with a pneumococcal conjugate vaccine. Clin Diagn Lab Immunol 2001 0.93
70 Pneumococcal conjugate vaccination in toddlers: mucosal antibody response measured as circulating antibody-secreting cells and as salivary antibodies. Pediatr Infect Dis J 1999 0.93
71 Dose dependency of antibody response in infants and children to pneumococcal polysaccharides conjugated to tetanus toxoid. Vaccine 1999 0.92
72 Murine monoclonal antibodies to PorA of Neisseria meningitidis show reduced protective activity in vivo against B:15:P1.7,16 subtype variants in an infant rat infection model. Microb Pathog 2001 0.92
73 Susceptibility of gram-negative bacteria to the synergistic bactericidal action of serum and polymyxin B nonapeptide. Can J Microbiol 1986 0.91
74 Activation of cell-mediated immunity following immunization with pneumococcal conjugate or polysaccharide vaccine. Scand J Immunol 2001 0.90
75 Tolerability and immunogenicity of an eleven-valent pneumococcal conjugate vaccine in healthy toddlers. Pediatr Infect Dis J 2001 0.90
76 Serum and salivary anti-capsular antibodies in infants and children vaccinated with octavalent pneumococcal conjugate vaccines, PncD and PncT. Vaccine 2001 0.90
77 Dynamics of natural immunity caused by subclinical infections, case study on Haemophilus influenzae type b (Hib). Epidemiol Infect 2000 0.89
78 Clinical evaluation of new pneumococcal vaccines: the Finnish approach. Dev Biol Stand 1998 0.89
79 Maternal immunization with pneumococcal polysaccharide vaccine in the Philippines. Vaccine 2003 0.89
80 Specific antibody deficiency in children with recurrent respiratory infections: a controlled study with follow-up. Clin Exp Immunol 2013 0.87
81 Human antibodies to pneumococcal surface protein A in health and disease. Pediatr Infect Dis J 2000 0.87
82 Antibodies to Haemophilus influenzae type b polysaccharide affect bacterial adherence and multiplication. Infect Immun 1996 0.87
83 Simultaneous administration of Haemophilus influenzae type b capsular polysaccharide-diphtheria toxoid conjugate vaccine with routine diphtheria-tetanus-pertussis and inactivated poliovirus vaccinations of childhood. Pediatr Infect Dis J 1988 0.87
84 Comparison of five different vaccination schedules with Haemophilus influenzae type b-tetanus toxoid conjugate vaccine. J Pediatr 1996 0.87
85 Mechanism of antibody-mediated reduction of nasopharyngeal colonization by Haemophilus influenzae type b studied in an infant rat model. J Infect Dis 1996 0.86
86 A comparison of early and late vaccination with Haemophilus influenzae type b conjugate and pneumococcal polysaccharide vaccines after allogeneic BMT. Bone Marrow Transplant 1996 0.85
87 Clinical experience with Haemophilus influenzae type b conjugate vaccines. Pediatrics 1990 0.85
88 Class-specific antibody response to Haemophilus influenzae type b capsular polysaccharide vaccine. J Infect Dis 1983 0.85
89 Booster response to the tetanus and diphtheria toxoid carriers of 11-valent pneumococcal conjugate vaccine in adults and toddlers. Vaccine 2001 0.85
90 Opsonophagocytic activity against Streptococcus pneumoniae type 19F in allogeneic BMT recipients before and after vaccination with pneumococcal polysaccharide vaccine. Bone Marrow Transplant 2001 0.85
91 Loss of protective immunity to polio, diphtheria and Haemophilus influenzae type b after allogeneic bone marrow transplantation. APMIS 1996 0.85
92 Do antibodies to pneumococcal surface adhesin a prevent pneumococcal involvement in acute otitis media? J Infect Dis 2001 0.84
93 Effect of Gm allotypes on IgG2 antibody responses and IgG2 concentrations in children and adults. Int Immunol 1990 0.83
94 A randomized study on donor immunization with tetanus-diphtheria, Haemophilus influenzae type b and inactivated poliovirus vaccines to improve the recipient responses to the same vaccines after allogeneic bone marrow transplantation. Bone Marrow Transplant 2007 0.83
95 IgG subclasses and avidity of antibodies to polysaccharide antigens in allogeneic BMT recipients after vaccination with pneumococcal polysaccharide and Haemophilus influenzae type b conjugate vaccines. Bone Marrow Transplant 1999 0.83
96 Tetravalent meningococcal polysaccharide vaccine is immunogenic in adult allogeneic BMT recipients. Bone Marrow Transplant 2001 0.83
97 Haemophilus influenzae type b and cross-reactive antigens in natural Hib infection dynamics; modelling in two populations. Epidemiol Infect 2002 0.82
98 Immunologic priming by one dose of Haemophilus influenzae type b conjugate vaccine in infancy. J Infect Dis 1995 0.82
99 The unspecific antibody response to N. meningitidis group A capsular polysaccharide often seen in bacteraemic diseases. Parasite Immunol 1982 0.82
100 Immunization with meningococcal class 1 outer membrane protein produced in Bacillus subtilis and reconstituted in the presence of Zwittergent or Triton X-100. Vaccine 1996 0.82
101 Secondary cases of invasive disease caused by spread of Haemophilus influenzae type b. J Infect 1987 0.82
102 Interactions of Haemophilus influenzae with human endothelial cells in vitro. J Infect Dis 1992 0.82
103 Subclass distribution of natural salivary IgA antibodies against pneumococcal capsular polysaccharide of type 14 and pneumococcal surface adhesin A (PsaA) in children. Clin Exp Immunol 2006 0.81
104 Antibodies to pneumolysin and pneumococcal capsular polysaccharides in middle ear fluid of children with acute otitis media. Acta Otolaryngol 1995 0.81
105 Determination of antibody responses to meningococcal antigens by ELISA. Methods Mol Med 2001 0.81
106 Nasopharyngeal antibodies to pneumococcal pneumolysin in children with acute otitis media. Clin Diagn Lab Immunol 1995 0.81
107 Passively acquired anti-tetanus and anti-Haemophilus antibodies and the response to Haemophilus influenzae type b-tetanus toxoid conjugate vaccine in infancy. Pediatr Infect Dis J 1996 0.81
108 Experience in Finland with Haemophilus influenzae type b vaccines. Vaccine 1991 0.80
109 Effect of transplacentally acquired tetanus antibodies on the antibody responses to Haemophilus influenzae type b-tetanus toxoid conjugate and tetanus toxoid vaccines in Filipino infants. Pediatr Infect Dis J 1999 0.80
110 Subclass distribution of IgA antibodies in saliva and serum after immunization with Haemophilus influenzae type b conjugate vaccines. Clin Exp Immunol 1998 0.80
111 Effects of sample collection and storage methods on antipneumococcal immunoglobulin A in saliva. Clin Diagn Lab Immunol 2003 0.79
112 B and T cell immunity in patients with lysinuric protein intolerance. Clin Exp Immunol 1999 0.79
113 A hierarchical Bayesian model to predict the duration of immunity to Haemophilus influenzae type b. Biometrics 1999 0.79
114 Nasopharyngeal antibodies to pneumococcal capsular polysaccharides in children with acute otitis media. J Infect Dis 1995 0.79
115 [Were the meningococcal vaccination campaigns in 1974-76 of benefit?]. Duodecim 1983 0.78
116 Antibody-secreting cells and their relation to humoral antibodies in serum and in nasopharyngeal aspirates in children with pneumococcal acute otitis media. J Infect Dis 1996 0.78
117 Vaccination responses to capsular polysaccharides of Neisseria meningitidis and Haemophilus influenzae type b in two C2-deficient sisters: alternative pathway-mediated bacterial killing and evidence for a novel type of blocking IgG. J Clin Immunol 2000 0.78
118 New vaccines for prevention of pneumococcal infections. Ann Med 1995 0.78
119 Haemophilus influenzae type b polysaccharide-protein conjugate vaccines in children. Curr Opin Pediatr 1993 0.77
120 Immunogenicity and reactogenicity of diphtheria, tetanus and pertussis toxoids combined with inactivated polio vaccine, when administered concomitantly with or as a diluent for a Hib conjugate vaccine. Vaccine 2001 0.77
121 Antibody response to Haemophilus influenzae type-b conjugate vaccine in children and young adults with congenital asplenia or after undergoing splenectomy. Eur J Clin Microbiol Infect Dis 2011 0.77
122 Concentrations of serum immunoglobulins and antibodies to pneumococcal capsular polysaccharides in patients with recurrent or chronic sinusitis. Ann Otol Rhinol Laryngol 2001 0.77
123 Latex agglutination test for screening of Haemophilus influenzae type b carriers. J Clin Microbiol 1987 0.77
124 Finnish efficacy trials with Haemophilus influenzae type b vaccines. J Infect Dis 1992 0.76
125 Early immunization with conjugate vaccines. Vaccine 1998 0.76
126 Vaccination of children during treatment for leukemia. Acta Paediatr Scand 1986 0.75
127 Serum antibodies against haemophilus influenzae type b and tetanus at 2.5 years of age: a follow-up of 2 different regimens of infant vaccination. Scand J Infect Dis 1996 0.75
128 [Severe Haemophilus influenzae infections in children are contagious]. Duodecim 1986 0.75
129 Vaccines for Haemophilus influenzae type b as models for an otitis vaccine. Pediatr Infect Dis J 1989 0.75
130 Reactogenicity and immunogenicity of combined vaccines for bacteraemic diseases caused by Haemophilus influenzae type b, meningococci and pneumococci in 24-month-old children. Vaccine 1990 0.75
131 [New specific bacterial vaccines]. Duodecim 1976 0.75
132 Antibodies against Haemophilus influenzae type b and tetanus in infants after subcutaneous vaccination with PRP-T/diphtheria, or PRP-OMP/diphtheria-tetanus vaccines. Pediatr Infect Dis J 1994 0.75
133 Antibody responses of three Haemophilus influenzae type b conjugate vaccines after one, two and three doses in Filipino children. Vaccine 1998 0.75
134 [Why is the genome sequencing of meningococcus useful for us?]. Duodecim 2000 0.75
135 [Vaccine against Haemophilus influenzae type b--antibody response and adverse effects]. Tidsskr Nor Laegeforen 1995 0.75
136 [The bactericidal action of human neutrophils on meningococci in vitro]. Zh Mikrobiol Epidemiol Immunobiol 2000 0.75
137 Studies on a Hib-tetanus toxoid conjugate vaccine: effects of co-administered tetanus toxoid vaccine, of administration route and of combined administration with an inactivated polio vaccine. Vaccine 1999 0.75
138 Detection of antibody responses against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis proteins in children with community-acquired pneumonia: effects of combining pneumococcal antigens, pre-existing antibody levels, sampling interval, age, and duration of illness. Eur J Clin Microbiol Infect Dis 2015 0.75
139 Recurrent meningococcal meningitis due to partial complement defects and poor anti-meningococcal antibody response. J Infect 1983 0.75