Published in Biophys J on February 01, 2000
Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster. Nat Struct Biol (2003) 1.71
Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, II: Fluorescence and vibrational spectroscopy using a cyanophenylalanine probe. Biophys J (2009) 1.16
Four-alpha-helix bundle with designed anesthetic binding pockets. Part II: halothane effects on structure and dynamics. Biophys J (2008) 1.03
Structure-based engineering of internal cavities in coiled-coil peptides. Biochemistry (2005) 0.97
Four-alpha-helix bundle with designed anesthetic binding pockets. Part I: structural and dynamical analyses. Biophys J (2008) 0.95
Mechanism of interaction between the general anesthetic halothane and a model ion channel protein, I: Structural investigations via X-ray reflectivity from Langmuir monolayers. Biophys J (2009) 0.94
Connexin channels and phospholipids: association and modulation. BMC Biol (2009) 0.94
A model membrane protein for binding volatile anesthetics. Biophys J (2004) 0.93
Monolayers of a model anesthetic-binding membrane protein: formation, characterization, and halothane-binding affinity. Biophys J (2006) 0.91
An isothermal titration calorimetry study on the binding of four volatile general anesthetics to the hydrophobic core of a four-alpha-helix bundle protein. Biophys J (2003) 0.90
Anesthesia, surgery, illness and Alzheimer's disease. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.90
Kinetics of anesthetic-induced conformational transitions in a four-alpha-helix bundle protein. Biochemistry (2006) 0.83
Shedding Light on Anesthetic Mechanisms: Application of Photoaffinity Ligands. Anesth Analg (2016) 0.76
The Molecular Mechanisms of Anesthetic Action: Updates and Cutting Edge Developments from the Field of Molecular Modeling. Pharmaceuticals (Basel) (2010) 0.75
The effect of the cosolvent trifluoroethanol on a tryptophan side chain orientation in the hydrophobic core of troponin C. Protein Sci (2009) 0.75
The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science (1998) 39.86
Spectroscopic determination of tryptophan and tyrosine in proteins. Biochemistry (1967) 21.79
Experimentally determined hydrophobicity scale for proteins at membrane interfaces. Nat Struct Biol (1996) 8.57
Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science (1996) 8.34
The solubility of amino acids and two glycine peptides in aqueous ethanol and dioxane solutions. Establishment of a hydrophobicity scale. J Biol Chem (1971) 8.06
Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature (1997) 7.49
Molecular and cellular mechanisms of general anaesthesia. Nature (1994) 6.94
A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids. Science (1990) 6.60
The interpretation of protein structures: total volume, group volume distributions and packing density. J Mol Biol (1974) 5.39
Conformation of amino acid side-chains in proteins. J Mol Biol (1978) 4.36
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle. Nature (1989) 4.25
How calmodulin binds its targets: sequence independent recognition of amphiphilic alpha-helices. Trends Biochem Sci (1990) 4.04
Analysis of the relationship between side-chain conformation and secondary structure in globular proteins. J Mol Biol (1987) 3.63
Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils. J Biol Chem (1984) 3.45
The lateral pressure profile in membranes: a physical mechanism of general anesthesia. Biochemistry (1997) 2.87
Membrane proteins: from sequence to structure. Annu Rev Biophys Biomol Struct (1994) 2.75
Protein design: a hierarchic approach. Science (1995) 2.73
Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin. Nat Med (1998) 2.71
Design and synthesis of multi-haem proteins. Nature (1994) 2.59
Direct observation of fast protein folding: the initial collapse of apomyoglobin. Proc Natl Acad Sci U S A (1996) 2.50
Molecular interactions between inhaled anesthetics and proteins. Pharmacol Rev (1997) 2.31
Binding of halothane to serum albumin demonstrated using tryptophan fluorescence. Anesthesiology (1995) 1.76
Quantitative determination of helical propensities from trifluoroethanol titration curves. Biochemistry (1994) 1.75
Synthetic model proteins. Positional effects of interchain hydrophobic interactions on stability of two-stranded alpha-helical coiled-coils. J Biol Chem (1992) 1.73
Bound volatile general anesthetics alter both local protein dynamics and global protein stability. Anesthesiology (1999) 1.63
On the role of methionine residues in the sequence-independent recognition of nonpolar protein surfaces. Biochemistry (1991) 1.52
The bacterial photosynthetic reaction center as a model for membrane proteins. Annu Rev Biochem (1989) 1.51
Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition. FASEB J (1995) 1.41
Tryptophan fluorescence quenching by methionine and selenomethionine residues of calmodulin: orientation of peptide and protein binding. Biochemistry (1998) 1.27
Development of monoclonal antibodies for measurement of immunoglobulin G antibody responses in blue and gold macaws (Ara ararauna). Am J Vet Res (1996) 1.24
An inhalational anesthetic binding domain in the nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A (1996) 1.24
Ferredoxin and ferredoxin-heme maquettes. Proc Natl Acad Sci U S A (1996) 1.22
Cysteinyl-tRNA synthetase from Escherichia coli does not need an editing mechanism to reject serine and alanine. High binding energy of small groups in specific molecular interactions. Biochemistry (1979) 1.21
A designed cavity in the hydrophobic core of a four-alpha-helix bundle improves volatile anesthetic binding affinity. Biochemistry (1998) 1.20
Halothane binding to soluble proteins determined by photoaffinity labeling. Anesthesiology (1993) 1.19
19F-NMR spin-spin relaxation (T2) method for characterizing volatile anesthetic binding to proteins. Analysis of isoflurane binding to serum albumin. Biochemistry (1992) 1.18
Hydrophobicity scale for proteins based on inverse temperature transitions. Biopolymers (1992) 1.15
Effects of anesthetics on the structure of a phospholipid bilayer: molecular dynamics investigation of halothane in the hydrated liquid crystal phase of dipalmitoylphosphatidylcholine. Biophys J (1998) 1.08
Volatile anesthetics compete for common binding sites on bovine serum albumin: a 19F-NMR study. Proc Natl Acad Sci U S A (1993) 1.08
Equilibrium dissociation and unfolding of the dimeric human papillomavirus strain-16 E2 DNA-binding domain. Protein Sci (1996) 1.06
Halothane blocks low-voltage-activated calcium current in rat sensory neurons. J Neurosci (1991) 1.01
Global topology & stability and local structure & dynamics in a synthetic spin-labeled four-helix bundle protein. Biochemistry (1997) 0.99
Amino acid resolution of halothane binding sites in serum albumin. J Biol Chem (1996) 0.99
De novo design of native proteins: characterization of proteins intended to fold into antiparallel, rop-like, four-helix bundles. Biochemistry (1997) 0.95
Do specific or nonspecific interactions with proteins underlie inhalational anesthetic action? Mol Pharmacol (1998) 0.92
Binding of the volatile anesthetic chloroform to albumin demonstrated using tryptophan fluorescence quenching. J Biol Chem (1997) 0.87
Molecular dynamics simulation of a synthetic four-alpha-helix bundle that binds the anesthetic halothane. FEBS Lett (1999) 0.82
Partitioning of four modern volatile general anesthetics into solvents that model buried amino acid side-chains. Biophys Chem (1999) 0.82
Binding of the volatile anesthetic halothane to the hydrophobic core of a tetra-alpha-helix-bundle protein. J Pharmacol Exp Ther (1996) 0.80
Triplet state properties of tryptophan residues in complexes of mutated Escherichia coli single-stranded DNA binding proteins with single-stranded polynucleotides. Biophys J (1989) 0.79
Fluorescence quenching in a strongly helical peptide series: the role of noncovalent pathways in modulating electronic interactions. Biochemistry (1993) 0.77
Probing the structural features of volatile anesthetic binding sites with synthetic peptides. Toxicol Lett (1998) 0.76
Anesthetic-protein interaction: effects of volatile anesthetics on the secondary structure of poly(L-lysine). J Pharm Sci (1991) 0.76
Epidemiology and causation of coronary heart disease and stroke in India. Heart (2008) 3.60
Country profile: India. Lancet (1998) 2.40
Violence in America. Effective solutions. J Med Assoc Ga (1995) 2.38
Predicting adult metabolic syndrome from childhood body mass index: follow-up of the New Delhi birth cohort. Arch Dis Child (2008) 1.98
Indian medical journals. Lancet (1992) 1.86
The World Heart Federation's white book: impending global pandemic of cardiovascular diseases: challenges and opportunities for the prevention and control of cardiovascular diseases in developing countries and economies in transition. Can J Cardiol (2000) 1.77
Binding of halothane to serum albumin demonstrated using tryptophan fluorescence. Anesthesiology (1995) 1.76
Public health law in India: a framework for its application as a tool for social change. Natl Med J India (2010) 1.61
Retardation of coronary atherosclerosis with yoga lifestyle intervention. J Assoc Physicians India (2000) 1.57
Impact of alcohol on coronary heart disease in Indian men. Atherosclerosis (2010) 1.55
Impact of migration on coronary heart disease risk factors: comparison of Gujaratis in Britain and their contemporaries in villages of origin in India. Atherosclerosis (2005) 1.55
Measuring obesity among school-aged youth in India: a comparison of three growth references. Indian Pediatr (2010) 1.51
Inhibition of dopamine transport in rat brain synaptosomes by volatile anesthetics. Anesthesiology (1993) 1.47
External beam radiotherapy and intraluminal brachytherapy in advanced inoperable esophageal cancer: JIPMER experience. Am J Clin Oncol (2001) 1.43
Why are urban Indian 6th graders using more tobacco than 8th graders? Findings from Project MYTRI. Tob Control (2006) 1.42
Assessment of antianginal efficacy of long-acting sustained release isosorbide dinitrate in comparison with short-acting isosorbide dinitrate. Indian Heart J (1992) 1.37
Distribution of halothane in a dipalmitoylphosphatidylcholine bilayer from molecular dynamics calculations. Biophys J (2000) 1.34
Surveillance for risk factors of cardiovascular disease among an industrial population in southern India. Natl Med J India (2008) 1.33
In vitro anthelmintic activity of root-tuber extract of Flemingia vestita, an indigenous plant in Shillong, India. Parasitol Res (1997) 1.32
Measurement of cholesterol and triglycerides in dried serum and the effect of storage. Clin Chem (2001) 1.29
Social determinants of cardiovascular disease outcomes in Indians. Indian J Med Res (2010) 1.25
Adverse drug reaction profile of cisplatin-based chemotherapy regimen in a tertiary care hospital in India: An evaluative study. Indian J Pharmacol (2010) 1.21
A designed cavity in the hydrophobic core of a four-alpha-helix bundle improves volatile anesthetic binding affinity. Biochemistry (1998) 1.20
Prevalence and determinants of diabetes mellitus in the Indian industrial population. Diabet Med (2008) 1.18
Urologic complications after renal transplantation: a prospective randomized trial comparing different techniques of ureteric anastomosis and the use of prophylactic ureteric stents. Transplant Proc (1995) 1.17
A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in India. Nutr J (2011) 1.13
Lipid profile of coronary risk subjects following yogic lifestyle intervention. Indian Heart J (1999) 1.13
Kinetic, structural, and spectroscopic identification of geminate states of myoglobin: a ligand binding site on the reaction pathway. Biochemistry (1987) 1.13
Modelling the implications for hospital services of cervical cytology screening: a case history. J Oper Res Soc (1989) 1.11
Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung. Gene Ther (2011) 1.10
Management of hepatic venous outflow obstruction. Lancet (1993) 1.09
Opsoclonus-myoclonus following the intranasal usage of cocaine. J Neurol Neurosurg Psychiatry (1989) 1.09
Effects of anesthetics on the structure of a phospholipid bilayer: molecular dynamics investigation of halothane in the hydrated liquid crystal phase of dipalmitoylphosphatidylcholine. Biophys J (1998) 1.08
Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis? Circulation (1993) 1.08
Oxygen-dependent lipid peroxidation during lung ischemia. J Clin Invest (1991) 1.07
Xanthogranulomatous cholecystitis. Report of two cases. J S C Med Assoc (1976) 1.07
Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients. Am J Transplant (2010) 1.07
Double burden of underweight and overweight among children (10-19 years of age) of employees working in Indian industrial units. Natl Med J India (2010) 1.07
Barriers to ART adherence & follow ups among patients attending ART centres in Maharashtra, India. Indian J Med Res (2011) 1.06
Thymosin-beta(4) changes the conformation and dynamics of actin monomers. Biophys J (2000) 1.05
Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier. J Obes (2011) 1.02
The scientific basis of tobacco product regulation. World Health Organ Tech Rep Ser (2008) 1.02
Quantitative autoradiography of halothane binding in rat brain. J Pharmacol Exp Ther (1998) 1.02
Self-assembly of heme A and heme B in a designed four-helix bundle: implications for a cytochrome c oxidase maquette. Biochemistry (2000) 1.01
Management of acute coronary syndromes in secondary care settings in Kerala: impact of a quality improvement programme. Natl Med J India (2008) 1.01
Subtle overlapping deletions in the terminal region of chromosome 6q24.2-q26: three cases studied using FISH. Am J Med Genet (1999) 0.98
Assessing the value of different sources of information on meningococcal disease. Community Med (1989) 0.97
Formalin dab, the effective way of treating haemorrhagic radiation proctitis: a randomized trial from a tertiary care hospital in South India. Colorectal Dis (2012) 0.97
Evaluation of zinc against salinomycin toxicity in broilers. Indian J Physiol Pharmacol (2004) 0.96
Intrachromosomal triplication of 2q11.2-q21 in a severely malformed infant: case report and review of triplications and their possible mechanism. Am J Med Genet (1999) 0.96
General anesthetic binding to gramicidin A: the structural requirements. Biophys J (2000) 0.96
Incidence of rheumatic fever and prevalence of rheumatic heart disease in India. Int J Cardiol (1994) 0.96
Genetic differences in Native Americans and tacrolimus dosing after kidney transplantation. Transplant Proc (2013) 0.94
Impact of comprehensive cardiovascular risk reduction programme on risk factor clustering associated with elevated blood pressure in an Indian industrial population. Indian J Med Res (2012) 0.94
Westernization and tobacco use among young people in Delhi, India. Soc Sci Med (2010) 0.94
HLA, blood groups and secretor status in patients with established rheumatic fever and rheumatic heart disease. Tissue Antigens (1986) 0.93
Optimising non-viral gene delivery in a tumour spheroid model. J Gene Med (2006) 0.93
Long-term persistence of gene expression from adeno-associated virus serotype 5 in the mouse airways. Gene Ther (2006) 0.93
Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs. Diabetologia (2011) 0.93
Membrane structural perturbations caused by anesthetics and nonimmobilizers: a molecular dynamics investigation. Biophys J (2001) 0.92
Inhaled anesthetic modulation of amyloid beta(1-40) assembly and growth. Curr Alzheimer Res (2007) 0.92
Spinal cord decompression sickness after standard U.S. Navy air decompression. Mil Med (1986) 0.91
Effect of four helix bundle topology on heme binding and redox properties. Biochemistry (1998) 0.91
Genetic polymorphisms of glutathione-S-transferase genes (GSTM1, GSTT1 and GSTP1) and upper aerodigestive tract cancer risk among smokers, tobacco chewers and alcoholics in an Indian population. Eur J Cancer (2007) 0.91
CYP2E1 polymorphisms and gene-environment interactions in the risk of upper aerodigestive tract cancers among Indians. Pharmacogenomics (2008) 0.91
The burden of disease among the global poor. Lancet (1999) 0.91
Plasma homocysteine levels and cardiovascular risk in Indians. J Assoc Physicians India (2002) 0.90
Growth from birth to adulthood and peak bone mass and density data from the New Delhi Birth Cohort. Osteoporos Int (2012) 0.90
Nonoperative management of bile leaks following liver transplantation. Clin Transplant (2000) 0.89
A role for the metal binding domain in determining the DNA sequence selectivity of Fe-bleomycin. J Biol Chem (1990) 0.89
Molecular dynamics simulation of four-alpha-helix bundles that bind the anesthetic halothane. FEBS Lett (2000) 0.88
Lymphocyte subsets in acute rheumatic fever and rheumatic heart disease. Clin Cardiol (1989) 0.87
Minimum structural requirement for an inhalational anesthetic binding site on a protein target. Biochim Biophys Acta (1996) 0.87
Clustering of impaired glucose tolerance, hyperinsulinemia and dyslipidemia in young north Indian patients with coronary heart disease: a preliminary case-control study. Indian Heart J (2000) 0.86
Alcohol therapy for hypertrophic cardiomyopathy: is it time to toast? Circulation (1998) 0.86
Air and nitrox saturation decompression: a report of 4 schedules and 77 subjects. Undersea Biomed Res (1985) 0.85
Triglycerides and small dense low density lipoprotein in the discrimination of coronary heart disease risk in South Asian populations. Atherosclerosis (2009) 0.85
Interstitial deletion of chromosome 4, del(4)(q12q21.1), in a mentally retarded boy with a piebald trait, due to maternal insertion, ins(8;4). Am J Med Genet (1998) 0.84
Evolution in pancreas transplantation techniques: simultaneous kidney-pancreas transplantation using portal-enteric drainage without antilymphocyte induction. Ann Surg (1999) 0.84
Congenital solitary nonparasitic cyst of the liver in an infant. Indian J Gastroenterol (1985) 0.84
Effect of testosterone replacement on whole body glucose utilisation and other cardiovascular risk factors in males with idiopathic hypogonadotrophic hypogonadism. Horm Metab Res (1998) 0.84
Validation of self-reported smoking status by measuring serum cotinine levels: an Indian perspective. Natl Med J India (2010) 0.84
Mechanisms underlying the inotropic action of halothane on intact rat ventricular myocytes. Br J Anaesth (1999) 0.83
Eliciting a policy response for the rising epidemic of overweight-obesity in India. Obes Rev (2013) 0.83
Saturable binding of halothane to rat brain synaptosomes. Proc Natl Acad Sci U S A (1992) 0.83
Malignant pilomatrixoma. Report of a case. Acta Radiol Oncol (1984) 0.83
Pilot study: association of traditional and genetic risk factors and new-onset diabetes mellitus following kidney transplantation. Transplant Proc (2009) 0.82
Acute rejection risk in kidney transplant recipients on steroid-avoidance immunosuppression receiving induction with either antithymocyte globulin or basiliximab. Transplant Proc (2006) 0.82
Molecular dynamics simulation of a synthetic four-alpha-helix bundle that binds the anesthetic halothane. FEBS Lett (1999) 0.82
On the gains of seeding tobacco research in developing countries. Tob Control (2006) 0.82
Outcomes after simultaneous pancreas and kidney transplantation and the discriminative ability of the C-peptide measurement pretransplant among type 1 and type 2 diabetes mellitus. Transplant Proc (2010) 0.82
Congestive heart failure in acromegaly: A review of 6 cases. Indian J Endocrinol Metab (2012) 0.82
Progression of and recovery from pulmonary oxygen toxicity in humans exposed to 5 ATA air. Aviat Space Environ Med (1987) 0.82
The development of gene therapy for diseases of the lung. Cell Mol Life Sci (2004) 0.81
Hepatic venous outflow obstruction. Trop Gastroenterol (1998) 0.81
Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling. Biochemistry (2000) 0.81
Cyclosporine directly causes oxidative stress and promotes Epstein-Barr virus transformation of human B cells. J Surg Res (2001) 0.81
Anaphylactoid reaction to angiographic contrast media: recurrence despite pretreatment with corticosteroids. Cathet Cardiovasc Diagn (1984) 0.81
Human granulocytic ehrlichiosis in pancreas transplant recipients. Transpl Infect Dis (2001) 0.81
Direct ascent from shallow air saturation exposures. Undersea Biomed Res (1986) 0.81