A L Cheng

Author PubWeight™ 68.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stability of curcumin in buffer solutions and characterization of its degradation products. J Pharm Biomed Anal 1997 2.77
2 Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice. Hum Mol Genet 1999 1.86
3 Hepatitis B virus X protein inhibits transforming growth factor-beta -induced apoptosis through the activation of phosphatidylinositol 3-kinase pathway. J Biol Chem 2000 1.40
4 Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis. Carcinogenesis 2000 1.34
5 Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: a clinicopathologic and molecular analysis. Blood 1991 1.32
6 Phase II study of weekly oxaliplatin and 24-h infusion of high-dose 5-fluorouracil and folinic acid in the treatment of advanced gastric cancer. Br J Cancer 2004 1.27
7 High-dose 5-fluorouracil infusional therapy is associated with hyperammonaemia, lactic acidosis and encephalopathy. Br J Cancer 1997 1.24
8 Clinicopathological and molecular biological features of colorectal cancer in patients less than 40 years of age. Br J Surg 2003 1.19
9 Cellular defects and altered gene expression in PC12 cells stably expressing mutant huntingtin. J Neurosci 1999 1.13
10 Clinicopathological spectrum of haemophagocytic syndrome in Epstein-Barr virus-associated peripheral T-cell lymphoma. Br J Haematol 1994 1.11
11 Prospective study of Helicobacter pylori eradication therapy in stage I(E) high-grade mucosa-associated lymphoid tissue lymphoma of the stomach. J Clin Oncol 2001 1.10
12 Hemophagocytic syndrome in Epstein-Barr virus-associated T-lymphoproliferative disorders: disease spectrum, pathogenesis, and management. Leuk Lymphoma 1995 1.10
13 Hypermethylation of the p16 gene in sporadic T3N0M0 stage colorectal cancers: association with DNA replication error and shorter survival. Oncology 1999 1.09
14 Metaplastic carcinoma of the breast: analysis of eight Asian patients with special emphasis on two unusual cases presenting with inflammatory-type breast cancer. Anticancer Res 2000 1.08
15 Weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin in the treatment of advanced gastric cancers. An effective and low-toxic regimen for patients with poor general condition. Oncology 1997 1.07
16 High expression of thymidylate synthase is associated with the drug resistance of gastric carcinoma to high dose 5-fluorouracil-based systemic chemotherapy. Cancer 1998 1.06
17 Cutaneous manifestations of postthymic T cell malignancies: description of five clinicopathologic subtypes. J Am Acad Dermatol 1990 1.04
18 Inhibition by curcumin of diethylnitrosamine-induced hepatic hyperplasia, inflammation, cellular gene products and cell-cycle-related proteins in rats. Food Chem Toxicol 2000 0.99
19 Expression of P-glycoprotein and p53 in advanced hepatocellular carcinoma treated by single agent chemotherapy: clinical correlation. J Gastroenterol Hepatol 1997 0.97
20 Chemotherapy alone versus surgery followed by chemotherapy for stage I/IIE large-cell lymphoma of the stomach. Am J Hematol 2000 0.97
21 Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis. Hum Mol Genet 2000 0.96
22 Phase I study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients. Cancer Chemother Pharmacol 2015 0.96
23 Detection of circulating cancer cells by nested reverse transcription-polymerase chain reaction of cytokeratin-19 (K19)--possible clinical significance in advanced gastric cancer. Anticancer Res 1998 0.96
24 Lack of efficacy to systemic chemotherapy for treatment of metaplastic carcinoma of the breast in the modern era. Breast Cancer Res Treat 2011 0.93
25 Quiescent nasal T/NK cell lymphoma manifested as primary central nervous system lymphoma. Am J Hematol 1999 0.93
26 A phase II study of weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin (HDFL) in the treatment of recurrent or metastatic colorectal cancers. Anticancer Res 1998 0.92
27 Menadione-induced DNA damage in a human tumor cell line. Biochem Pharmacol 1991 0.91
28 Gastric cancer associated with acute disseminated intravascular coagulation: successful initial treatment with weekly 24-hour infusion of high-dose 5-fluorouracil and leucovorin. Br J Haematol 1998 0.91
29 Menadione: spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines. Biochem Pharmacol 1991 0.91
30 Steroid-free chemotherapy decreases the risk of hepatitis flare-up in hepatitis B virus carriers with non-Hodgkin's lymphoma. Blood 1996 0.89
31 Epstein-Barr virus-containing T-cell lymphoma presents with hemophagocytic syndrome mimicking malignant histiocytosis. Cancer 1993 0.89
32 Prolonged and enhanced suppression of thymidylate synthase by weekly 24-h infusion of high-dose 5-fluorouracil. Br J Cancer 2000 0.89
33 Acute confusion induced by a high-dose infusion of 5-fluorouracil and folinic acid. J Formos Med Assoc 1994 0.87
34 Retinoic acid-induced apoptotic pathway in T-cell lymphoma: Identification of four groups of genes with differential biological functions. Exp Hematol 2000 0.87
35 Angioimmunoblastic lymphadenopathy with dysproteinemia--lack of a prognostic value of clear cell morphology. Oncology 1997 0.86
36 Characterization of the spectrum of postthymic T-cell malignancies in Taiwan. A clinicopathologic study of HTLV-1-positive and HTLV-1-negative cases. Cancer 1988 0.86
37 Single-step direct cloning of PCR products. Trends Genet 1995 0.86
38 Clinicopathologic characteristics of Helicobacter pyloric seropositive gastric adenocarcinomas. J Clin Gastroenterol 1995 0.86
39 An alternative method to overcome central venous portable external infusion pump blockage in patients receiving weekly 24-hour high-dose fluorouracil and leucovorin. J Clin Oncol 1994 0.86
40 An open, multi-centre, phase II clinical trial to evaluate the efficacy and safety of paclitaxel, UFT, and leucovorin in patients with advanced gastric cancer. Br J Cancer 2006 0.85
41 Analysis of the cellular basis of keratinocyte growth factor overexpression in inflammatory bowel disease. Gut 1999 0.84
42 Clinicopathologic, cytogenetic, and molecular studies of 13 Chinese Patients with Ki-1 anaplastic large cell lymphoma. Special emphasis on the tumor response to 13-cis retinoic acid. Cancer 1996 0.84
43 Minimal toxicity to myeloid progenitor cells of weekly 24-hr infusion of high-dose 5-fluorouracil: direct evidence from colony forming unit-granulocyte and monocyte (CFU-GM) clonogenic assay. Pharmacol Toxicol 2000 0.82
44 Transactivation of the human MDR1 gene by hepatitis B virus X gene product. J Hepatol 1998 0.82
45 Infrequent hMSH2 mutations in sporadic gastric adenocarcinoma with microsatellite instability. Cancer Lett 1997 0.81
46 Combined cytotoxic effects of tamoxifen and chemotherapeutic agents on bladder cancer cells: a potential use in intravesical chemotherapy. Br J Urol 1996 0.80
47 Overexpression of p53 is not associated with drug resistance of gastric cancers to 5-fluorouracil-based systemic chemotherapy. Hepatogastroenterology 1999 0.80
48 Cutaneous manifestations of Epstein-Barr virus-associated T-cell lymphoma. J Am Acad Dermatol 1993 0.80
49 Retinoic acid-induced apoptosis and regression of a refractory Epstein-Barr virus-containing T cell lymphoma expressing multidrug-resistance phenotypes. Br J Haematol 1993 0.80
50 Expression of MDR-1 gene in transitional cell carcinoma and its correlation with chemotherapy response. J Urol 1996 0.80
51 Concurrent chemoradiotherapy for locally advanced esophageal cancer--a pilot study by using daily low-dose cisplatin and continuous infusion of 5-fluorouracil. Anticancer Res 2000 0.80
52 Disruption of cellular energy balance by suramin in intact human prostatic carcinoma cells, a likely antiproliferative mechanism. Cancer Res 1991 0.79
53 The significance of body weight change in non-Hodgkins lymphoma. Anticancer Res 2000 0.79
54 Keratinocyte growth factor down-regulates expression of the sucrase-isomaltase gene in Caco-2 intestinal epithelial cells. J Biol Chem 1998 0.79
55 High dose tamoxifen plus cisplatin and etoposide in the treatment of patients with advanced, inoperable nonsmall cell lung carcinoma. Cancer 1999 0.79
56 Tamoxifen enhances the chemosensitivity of bladder carcinoma cells. J Urol 1995 0.79
57 Bone marrow involvement in non-Hodgkin's lymphoma. Taiwan Yi Xue Hui Za Zhi 1989 0.79
58 Primary T cell leptomeningeal lymphoma--successful treatment with systemic chemotherapy. Oncology 1995 0.79
59 Bcl-2 prevents topoisomerase II inhibitor GL331-induced apoptosis is mediated by down-regulation of poly(ADP-ribose)polymerase activity. Oncogene 1998 0.78
60 Thymic carcinoma with autoimmune syndrome: successful treatment with weekly infusional high-dose 5-fluorouracil and leucovorin. Anticancer Res 1997 0.78
61 Gemcitabine and cisplatin in a multimodality treatment for locally advanced non-small cell lung cancer. Br J Cancer 2002 0.78
62 Comparison of MALT and non-MALT primary large cell lymphoma of the stomach: does histologic evidence of MALT affect chemotherapy response? Cancer 2001 0.78
63 Nuclear extracellular signal-regulated kinase 2 phosphorylates p53 at Thr55 in response to doxorubicin. Biochem Biophys Res Commun 2001 0.78
64 Adult non-Hodgkin's lymphoma in Taiwan area: a clinicopathologic study of 123 cases based on working formulation classification. Taiwan Yi Xue Hui Za Zhi 1989 0.77
65 Renal clearance, tissue distribution, and CA-125 responses in a phase I trial of suramin. Clin Cancer Res 1998 0.77
66 Cutaneous angiocentric T-cell lymphoma associated with Epstein-Barr virus. J Am Acad Dermatol 1992 0.77
67 Relatively low expression of multidrug resistance-1 (MDR-1) and its possible clinical implication in gastric cancers. J Clin Gastroenterol 1998 0.77
68 Transforming growth factor beta1 attenuates ceramide-induced CPP32/Yama activation and apoptosis in human leukaemic HL-60 cells. Biochem J 1997 0.77
69 Tax of the human T-lymphotropic virus type I transactivates promoter of the MDR-1 gene. Biochem Biophys Res Commun 1997 0.76
70 Combination chemotherapy of cisplatin, methotrexate, vinblastine, and high-dose tamoxifen for transitional cell carcinoma. Anticancer Res 2001 0.76
71 13-cis-retinoic acid induces cellular differentiation and durable remission in refractory cutaneous Ki-1 lymphoma. Cancer 1991 0.76
72 Polyprenoic acid in hepatocellular carcinoma. N Engl J Med 1996 0.75
73 Phase II study of weekly vinorelbine and 24-h infusion of high-dose 5-fluorouracil plus leucovorin as first-line treatment of advanced breast cancer. Br J Cancer 2005 0.75
74 Five-drug combination chemotherapy (FAPEL) for advanced gastric cancer: a pilot study. J Formos Med Assoc 1994 0.75
75 High-dose tamoxifen reverses drug resistance to cisplatin and etoposide in a patient with advanced large cell carcinoma of lung. Anticancer Res 1997 0.75
76 Weekly CAF chemotherapy for advanced breast cancer patients. Oncology 1997 0.75
77 High-dose therapy with peripheral blood stem cell (PBSC) support using an innovative mobilization regimen in patients with high-risk primary or chemoresponsive metastatic breast cancers. Breast Cancer Res Treat 1998 0.75
78 A pilot study of AFL-T (doxorubicin, 5-fluorouracil, leucovorin, and tamoxifen) combination chemotherapy for hormone-refractory prostate cancer. Anticancer Res 2001 0.75
79 Treatment of recurrent Kaposi's sarcoma of an AIDS patient with weekly paclitaxel. Anticancer Res 2000 0.75
80 Present status of cancer treatment in Taiwan. Gan To Kagaku Ryoho 1992 0.75
81 Adult acute lymphoblastic leukemia--lineage specific classification of 30 cases. Taiwan Yi Xue Hui Za Zhi 1986 0.75
82 Low-grade gastric B-cell lymphoma of mucosa-associated lymphoid tissue: clinicopathologic analysis of 19 cases. J Formos Med Assoc 1996 0.75
83 Megestrol acetate antagonizes cisplatin cytotoxicity. Anticancer Drugs 1998 0.75
84 Prognostic significance of immunophenotypes in adult lymphoblastic lymphomas. Anticancer Res 1997 0.75
85 MVP (mitomycin-C, vinblastine, cisplatin) salvage chemotherapy for relapsed and refractory metastatic breast cancer. J Formos Med Assoc 1997 0.75
86 Expression of growth-related genes and drug-resistance genes in HTLV-I-positive and HTLV-I-negative post-thymic T-cell malignancies. Ann Oncol 1991 0.75
87 [Allogeneic bone marrow transplantation in the treatment of leukemia--a preliminary report]. Taiwan Yi Xue Hui Za Zhi 1987 0.75