PubRank

B W Bycroft

Author PubWeight™ 95.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology 1997 7.83
2 The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa. EMBO J 1993 5.35
3 Multiple homologues of LuxR and LuxI control expression of virulence determinants and secondary metabolites through quorum sensing in Pseudomonas aeruginosa PAO1. Mol Microbiol 1995 5.12
4 Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A 1995 4.77
5 The bacterial 'enigma': cracking the code of cell-cell communication. Mol Microbiol 1995 4.66
6 A general role for the lux autoinducer in bacterial cell signalling: control of antibiotic biosynthesis in Erwinia. Gene 1992 4.56
7 Construction and analysis of luxCDABE-based plasmid sensors for investigating N-acyl homoserine lactone-mediated quorum sensing. FEMS Microbiol Lett 1998 4.36
8 N-(3-oxohexanoyl)-L-homoserine lactone regulates carbapenem antibiotic production in Erwinia carotovora. Biochem J 1992 3.40
9 The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect Immun 1998 3.16
10 Engineering the luxCDABE genes from Photorhabdus luminescens to provide a bioluminescent reporter for constitutive and promoter probe plasmids and mini-Tn5 constructs. FEMS Microbiol Lett 1998 2.65
11 Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria. Mol Microbiol 1999 2.59
12 Autoregulation of carbapenem biosynthesis in Erwinia carotovora by analogues of N-(3-oxohexanoyl)-L-homoserine lactone. J Antibiot (Tokyo) 1993 2.53
13 Quorum sensing and the population-dependent control of virulence. Philos Trans R Soc Lond B Biol Sci 2000 2.17
14 Characterisation of the yenI/yenR locus from Yersinia enterocolitica mediating the synthesis of two N-acylhomoserine lactone signal molecules. Mol Microbiol 1995 2.15
15 N-acyl homoserine lactone binding to the CarR receptor determines quorum-sensing specificity in Erwinia. EMBO J 2000 1.92
16 Quorum sensing in Vibrio anguillarum: characterization of the vanI/vanR locus and identification of the autoinducer N-(3-oxodecanoyl)-L-homoserine lactone. J Bacteriol 1997 1.87
17 Small molecule-mediated density-dependent control of gene expression in prokaryotes: bioluminescence and the biosynthesis of carbapenem antibiotics. FEMS Microbiol Lett 1992 1.76
18 Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus. Mol Microbiol 2001 1.65
19 Chitinolytic activity in Chromobacterium violaceum: substrate analysis and regulation by quorum sensing. J Bacteriol 1998 1.43
20 Quorum sensing: a novel target for anti-infective therapy. J Antimicrob Chemother 1998 1.41
21 The rap and hor proteins of Erwinia, Serratia and Yersinia: a novel subgroup in a growing superfamily of proteins regulating diverse physiological processes in bacterial pathogens. Mol Microbiol 1997 1.38
22 Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway. Mol Microbiol 1996 1.33
23 In vitro biosynthesis of the Pseudomonas aeruginosa quorum-sensing signal molecule N-butanoyl-L-homoserine lactone. Mol Microbiol 1998 1.30
24 Cryptic carbapenem antibiotic production genes are widespread in Erwinia carotovora: facile trans activation by the carR transcriptional regulator. Microbiology 1998 1.18
25 Solution structures of nisin A and its two major degradation products determined by n.m.r. Biochem J 1992 1.16
26 Analysis of the carbapenem gene cluster of Erwinia carotovora: definition of the antibiotic biosynthetic genes and evidence for a novel beta-lactam resistance mechanism. Mol Microbiol 1997 1.12
27 Role of transmembrane pH gradient and membrane binding in nisin pore formation. J Bacteriol 1997 1.11
28 Molecular analysis of the regulation of nisin immunity. Microbiology 1996 1.10
29 Structure-activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin. FEBS Lett 1996 1.08
30 Haemodynamic effects of the bacterial quorum sensing signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone, in conscious, normal and endotoxaemic rats. Br J Pharmacol 2001 1.07
31 Structural relationships in microbial peptides. Nature 1969 1.05
32 Structure-activity relationships in the peptide antibiotic nisin: role of dehydroalanine 5. Appl Environ Microbiol 1996 1.04
33 Interaction of the lantibiotic nisin with mixed lipid bilayers: a 31P and 2H NMR study. Biochemistry 2000 0.97
34 Sequence-specific resonance assignment and conformational analysis of subtilin by 2D NMR. FEBS Lett 1992 0.93
35 The action of natural and synthetic isomers of quisqualic acid at a well-defined glutamatergic synapse. Brain Res 1986 0.92
36 Studies on the metabolism of deoxynivalenol in the rat. Food Chem Toxicol 1987 0.90
37 A novel post-translational modification of the peptide antibiotic subtilin: isolation and characterization of a natural variant from Bacillus subtilis A.T.C.C. 6633. Biochem J 1993 0.90
38 Studies on the biosynthesis of clavulanic acid. III. Incorporation of DL-[3,4-13C2]glutamic acid. J Antibiot (Tokyo) 1982 0.87
39 Bacterial N-acyl-homoserine-lactone-dependent signalling and its potential biotechnological applications. Trends Biotechnol 1997 0.87
40 Confirmation of the structure of nisin and its major degradation product by FAB-MS and FAB-MS/MS. Experientia 1988 0.84
41 Metabolic conversions of trichothecene mycotoxins: biotransformation of 3-acetyldeoxynivalenol into fusarenon-X. Z Naturforsch C 1987 0.84
42 Alleviation of insulitis and moderation of diabetes in NOD mice following treatment with a synthetic Pseudomonas aeruginosa signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone. Acta Diabetol 2005 0.83
43 Molecular genetics of carbapenem antibiotic biosynthesis. Antonie Van Leeuwenhoek 1999 0.82
44 Biosynthesis of trichothecene mycotoxins: cell-free epoxidation of a trichodiene derivative. FEMS Microbiol Lett 1991 0.81
45 Bacterial production of carbapenems and clavams: evolution of beta-lactam antibiotic pathways. Trends Microbiol 1998 0.79
46 Total structure of capreomycin IB, a tuberculostatic peptide antibiotic. Nature 1971 0.78
47 Irreversible inactivation of beta-lactamase I from Bacillus cereus by chlorinated 6-spiroepoxypenicillins. Biochem J 1991 0.78
48 Dissection of the promoter/operator region and evaluation of N-acylhomoserine lactone mediated transcriptional regulation of elastase expression in Pseudomonas aeruginosa. FEMS Microbiol Lett 1997 0.78
49 Kynurenine aminotransferase activity in human liver: identity with human hepatic C-S lyase activity and a physiological role for this enzyme. Toxicol Lett 1992 0.78
50 Arthropod toxins as leads for novel insecticides: an assessment of polyamine amides as glutamate antagonists. Toxicon 1992 0.77
51 Fast atom bombardment mass spectrometry of bleomycin A2 and B2 and their metal complexes. Biochem Biophys Res Commun 1981 0.77
52 Human renal C-S lyases: two cytosolic isoenzymes. Toxicol Lett 1990 0.76
53 Biosynthesis of trichothecene mycotoxins in Fusarium culmorum cultures. Z Naturforsch C 1985 0.76
54 Human renal C-S lyase: structure-activity relationships of cytosolic and mitochondrial enzymes. Toxicol Lett 1990 0.76
55 Inhibition of rat renal C-S lyase: assessment using kidney slice methodology. Drug Metabol Drug Interact 1988 0.75
56 Studies in mycological chemistry. XXV. Experiments directed towards a synthesis of aflatoxin-G2: synthesis of the coumarino-lactone system. J Chem Soc Perkin 1 1970 0.75
57 Study of an actinomycin complex by mass spectrometry-mass spectrometry. Talanta 1988 0.75
58 Viomycin. II. The structure of the chromophore. J Chem Soc Perkin 1 1972 0.75
59 Synthesis of 2'-deoxyuridine and 5-fluoro-2'-deoxyuridine derivatives and evaluation in antibody targeting studies. J Med Chem 1993 0.75
60 Crystallographic studies and semi-empirical MNDO calculations on quisqualic acid and its analogues: systems containing unusual pyramidal heterocyclic ring nitrogens. J Comput Aided Mol Des 1989 0.75
61 Viomycin. I. The structure of the guanidine-containing unit. J Chem Soc Perkin 1 1972 0.75
62 Viomycin. Further degradative studies. Tetrahedron Lett 1968 0.75
63 [Determination of the absolute configuration of alkaloids of the aspidospermine group by means of optical comparison with alkaloids of the strychnine group]. Experientia 1964 0.75
64 The total structure of viomycin, a tuberculostatic peptide antibiotic. Experientia 1971 0.75
65 Revised constitution, absolute configuration, and conformation of griseoviridin, a modified cyclic peptide antibiotic. J Chem Soc Perkin 1 1976 0.75
66 Trichothecene mycotoxins from Fusarium culmorum cultures. Z Naturforsch C 1988 0.75
67 Highly conformationally constrained halogenated 6-spiroepoxypenicillins as probes for the bioactive side-chain conformation of benzylpenicillin. J Comput Aided Mol Des 1989 0.75
68 The chromophore and partial structure of viomycin. Tetrahedron Lett 1968 0.75
69 Synthesis of a model relating to the chromophores of capreomycin and viomycin. Tetrahedron Lett 1969 0.75
70 Small molecule mediated autoinduction of antibiotic biosynthesis in the plant pathogen Erwinia carotovora. Biochem Soc Trans 1995 0.75