Published in Biochemistry (Mosc) on January 01, 2000
Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression. Nat Med (2014) 2.47
Subversion of cell signaling pathways by hepatitis C virus nonstructural 5A protein via interaction with Grb2 and P85 phosphatidylinositol 3-kinase. J Virol (2002) 1.44
The enigmatic effects of caffeine in cell cycle and cancer. Cancer Lett (2006) 1.43
Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol Biol Cell (2001) 1.36
Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cancer. Oncologist (2011) 1.32
Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease. Curr Alzheimer Res (2010) 1.18
Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice. Int J Cancer (2012) 1.15
Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses. PLoS One (2011) 1.10
K-ras gene mutation enhances motility of immortalized airway cells and lung adenocarcinoma cells via Akt activation: possible contribution to non-invasive expansion of lung adenocarcinoma. Am J Pathol (2004) 1.10
The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis. Arthritis Res Ther (2006) 1.09
Tissue inhibitor of metalloproteinases-1 signalling pathway leading to erythroid cell survival. Biochem J (2003) 1.07
Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins. Eur J Pharmacol (2008) 1.03
Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism. Biochim Biophys Acta (2011) 1.01
PAK1 kinase is required for CXCL1-induced chemotaxis. Biochemistry (2002) 0.99
The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck. PLoS One (2009) 0.98
Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation. PLoS One (2012) 0.96
p27 Kip1 nuclear localization and cyclin-dependent kinase inhibitory activity are regulated by glycogen synthase kinase-3 in human colon cancer cells. Cell Death Differ (2008) 0.94
Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity. Proc Natl Acad Sci U S A (2004) 0.94
The basal level of intracellular calcium gates the activation of phosphoinositide 3-kinase-Akt signaling by brain-derived neurotrophic factor in cortical neurons. J Neurochem (2008) 0.88
Inhibitory effect of capsaicin on B16-F10 melanoma cell migration via the phosphatidylinositol 3-kinase/Akt/Rac1 signal pathway. Exp Mol Med (2008) 0.87
One year of complete clinical response in a metastatic breast cancer patient treated with a combination of lapatinib and gemcitabine. Curr Oncol (2010) 0.87
Cell migration and activated PI3K/AKT-directed elongation in the developing rat Müllerian duct. Dev Biol (2008) 0.87
Tumor necrosis factor-alpha promotes survival of opossum kidney cells via Cdc42-induced phospholipase C-gamma1 activation and actin filament redistribution. Mol Biol Cell (2003) 0.87
Cardioprotective Effects of Quercetin in Cardiomyocyte under Ischemia/Reperfusion Injury. Evid Based Complement Alternat Med (2013) 0.86
Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro. Breast Cancer Res (2005) 0.85
Phospholipid transfer protein reduces phosphorylation of tau in human neuronal cells. J Neurosci Res (2009) 0.85
Microarray analysis of gene expression in vestibular schwannomas reveals SPP1/MET signaling pathway and androgen receptor deregulation. Int J Oncol (2013) 0.84
Galectin-3 enhances angiogenic and migratory potential of microglial cells via modulation of integrin linked kinase signaling. Brain Res (2012) 0.84
Cell surface heparan sulfate participates in CXCL1-induced signaling. Biochemistry (2003) 0.83
Laminin-3B11, a novel vascular-type laminin capable of inducing prominent lamellipodial protrusions in microvascular endothelial cells. J Biol Chem (2010) 0.83
The p85 regulatory subunit of PI3K mediates cAMP-PKA and insulin biological effects on MCF-7 cell growth and motility. ScientificWorldJournal (2014) 0.83
A peptide from Porphyra yezoensis stimulates the proliferation of IEC-6 cells by activating the insulin-like growth factor I receptor signaling pathway. Int J Mol Med (2014) 0.82
CF101, an agonist to the A3 adenosine receptor, enhances the chemotherapeutic effect of 5-fluorouracil in a colon carcinoma murine model. Neoplasia (2005) 0.82
Modulation of integrin-linked kinase (ILK) expression in human oesophageal squamous cell carcinoma cell lines by the EGF and TGFbeta1 growth factors. Cancer Cell Int (2006) 0.81
The Biological Role of PI3K Pathway in Lung Cancer. Pharmaceuticals (Basel) (2012) 0.81
Fractalkine functions as a chemoattractant for osteoarthritis synovial fibroblasts and stimulates phosphorylation of mitogen-activated protein kinases and Akt. Clin Exp Immunol (2009) 0.81
Kaempferol Downregulates Insulin-like Growth Factor-I Receptor and ErbB3 Signaling in HT-29 Human Colon Cancer Cells. J Cancer Prev (2014) 0.80
Correlation between metastatic potential and variants from colorectal tumor cell line HT-29. World J Gastroenterol (2003) 0.79
Downregulation of β-actin and its regulatory gene HuR affect cell migration of human corneal fibroblasts. Mol Vis (2014) 0.78
Characterization of Golgi scaffold proteins and their roles in compartmentalizing cell signaling. J Mol Histol (2013) 0.78
Different expression of miRNAs targeting helicases in rice in response to low and high dose rate γ-ray treatments. Plant Signal Behav (2013) 0.77
miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer. Sci Rep (2016) 0.75
Influence of Pi3-K and PKC activity on 99mTc-(V)-DMSA uptake: correlation with tumour aggressiveness in an in vitro malignant glioblastoma cell line model. Eur J Nucl Med Mol Imaging (2006) 0.75