Published in Mech Dev on March 15, 2000
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet (2004) 3.21
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest (2004) 2.72
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
Evolutionary modification of development in mammalian teeth: quantifying gene expression patterns and topography. Proc Natl Acad Sci U S A (2000) 2.09
FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice. Genes Dev (2002) 1.88
Linking development with generation of novelty in mammalian teeth. Proc Natl Acad Sci U S A (2000) 1.87
Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Dev Biol (2009) 1.73
Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development (2004) 1.67
Development of the upper lip: morphogenetic and molecular mechanisms. Dev Dyn (2006) 1.61
A gene network model accounting for development and evolution of mammalian teeth. Proc Natl Acad Sci U S A (2002) 1.58
Pattern and regulation of cell proliferation during murine ureteric bud development. J Anat (2004) 1.49
A periodic pattern generator for dental diversity. BMC Biol (2008) 1.47
Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity. Evol Dev (2005) 1.38
Dental anomalies in the primary dentition of Turkish children. Eur J Dent (2012) 1.26
Unusual occurrence of accessory central cusp in the maxillary second primary molar. Contemp Clin Dent (2011) 1.25
Conserved deployment of genes during odontogenesis across osteichthyans. Proc Biol Sci (2004) 1.22
Wnt/beta-catenin signaling in oral tissue development and disease. J Dent Res (2010) 1.20
A curriculum vitae of teeth: evolution, generation, regeneration. Int J Biol Sci (2009) 1.19
Regeneration of dental-pulp-like tissue by chemotaxis-induced cell homing. Tissue Eng Part A (2010) 1.18
Smad4 is required to regulate the fate of cranial neural crest cells. Dev Biol (2007) 1.18
Stem cell-based biological tooth repair and regeneration. Trends Cell Biol (2010) 1.17
Functional tooth regeneration using a bioengineered tooth unit as a mature organ replacement regenerative therapy. PLoS One (2011) 1.17
Engineering stem cells into organs: topobiological transformations demonstrated by beak, feather, and other ectodermal organ morphogenesis. Curr Top Dev Biol (2006) 1.17
Multilevel complex interactions between genetic, epigenetic and environmental factors in the aetiology of anomalies of dental development. Arch Oral Biol (2009) 1.15
Adult human gingival epithelial cells as a source for whole-tooth bioengineering. J Dent Res (2013) 1.15
Epithelial stratification and placode invagination are separable functions in early morphogenesis of the molar tooth. Development (2016) 1.14
Constitutively active Akt induces ectodermal defects and impaired bone morphogenetic protein signaling. Mol Biol Cell (2007) 1.14
The genetic basis of modularity in the development and evolution of the vertebrate dentition. Philos Trans R Soc Lond B Biol Sci (2001) 1.10
Patterning by heritage in mouse molar row development. Proc Natl Acad Sci U S A (2010) 1.09
Expression of odontogenic ameloblast-associated protein (ODAM) in dental and other epithelial neoplasms. Mol Med (2008) 1.09
Conditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality. J Invest Dermatol (2010) 1.09
Essential role of osterix for tooth root but not crown dentin formation. J Bone Miner Res (2015) 1.07
Molecular patterning of the mammalian dentition. Semin Cell Dev Biol (2013) 1.05
Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (2013) 1.04
Regulation of facial morphogenesis by endothelin signaling: insights from mice and fish. Am J Med Genet A (2010) 1.04
The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol (2009) 1.03
Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis. J Exp Zool B Mol Dev Evol (2009) 1.02
Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice. Mol Cell Biol (2009) 1.02
SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development (2011) 1.00
Development of three-dimensional biomimetic scaffold to study epithelial-mesenchymal interactions. Tissue Eng Part A (2010) 0.98
Molecular regulatory mechanism of tooth root development. Int J Oral Sci (2012) 0.97
Phenogenetic drift in evolution: the changing genetic basis of vertebrate teeth. Proc Natl Acad Sci U S A (2005) 0.97
Development and evolution occlude: evolution of development in mammalian teeth. Proc Natl Acad Sci U S A (2000) 0.97
Dental abnormalities in Schimke immuno-osseous dysplasia. J Dent Res (2012) 0.95
Expression and regulation of the Msx1 natural antisense transcript during development. Nucleic Acids Res (2005) 0.95
The presence of accessory cusps in chimpanzee lower molars is consistent with a patterning cascade model of development. J Anat (2010) 0.95
Intra-epithelial requirement of canonical Wnt signaling for tooth morphogenesis. J Biol Chem (2013) 0.94
Modeling the dental development of fossil hominins through the inhibitory cascade. J Anat (2014) 0.93
Unique and shared gene expression patterns in Atlantic salmon (Salmo salar) tooth development. Dev Genes Evol (2008) 0.92
A talon cusp on fused teeth associated with hypodontia: report of a unique case. Eur J Dent (2010) 0.92
Post-natal effect of overexpressed DKK1 on mandibular molar formation. J Dent Res (2011) 0.90
Phosphate: known and potential roles during development and regeneration of teeth and supporting structures. Birth Defects Res C Embryo Today (2008) 0.90
Adipose tissue-derived stem cell in vitro differentiation in a three-dimensional dental bud structure. Am J Pathol (2011) 0.90
Morphogenetic fields within the human dentition: a new, clinically relevant synthesis of an old concept. Arch Oral Biol (2008) 0.89
Ameloblast differentiation in the human developing tooth: effects of extracellular matrices. Matrix Biol (2010) 0.89
Three dimensional dental epithelial-mesenchymal constructs of predetermined size and shape for tooth regeneration. Biomaterials (2010) 0.89
FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling. Development (2013) 0.89
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis. Biomaterials (2013) 0.89
Three-dimensional analysis of the early development of the dentition. Aust Dent J (2014) 0.88
Development of craniofacial structures in transgenic mice with constitutively active PTH/PTHrP receptor. Bone (2007) 0.88
Genetic, environmental and epigenetic influences on variation in human tooth number, size and shape. Odontology (2011) 0.88
Fibroblast growth factor signaling in mammalian tooth development. Odontology (2013) 0.88
Identification of the functional activity of the [A-4] amelogenin gene splice product in newborn mouse ameloblasts. Bone (2008) 0.88
Prevalence of aberrant dental morphological details in 6-10 year old school children in an Indian population. Contemp Clin Dent (2015) 0.88
Novel mutations in GJA1 cause oculodentodigital syndrome. J Dent Res (2008) 0.87
Molars and incisors: show your microarray IDs. BMC Res Notes (2013) 0.87
Developmentally-inspired shrink-wrap polymers for mechanical induction of tissue differentiation. Adv Mater (2014) 0.87
The canonical BMP signaling pathway plays a crucial part in stimulation of dentin sialophosphoprotein expression by BMP-2. J Biol Chem (2010) 0.87
The Amelogenin Proteins and Enamel Development in Humans and Mice. J Oral Biosci (2011) 0.87
Appositional enamel growth in molars of South African fossil hominids. J Anat (2006) 0.86
Molecular and circadian controls of ameloblasts. Eur J Oral Sci (2011) 0.86
Tooth-forming potential in embryonic and postnatal tooth bud cells. Med Mol Morphol (2008) 0.85
Possible involvement of melatonin in tooth development: expression of melatonin 1a receptor in human and mouse tooth germs. Histochem Cell Biol (2010) 0.85
Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One (2012) 0.84
Immunolocalization of fibroblast growth factor-2 (FGF-2) in the developing root and supporting structures of the murine tooth. J Mol Histol (2005) 0.84
An ideal society? Neighbors of diverse origins interact to create and maintain complex mini-organs in the skin. PLoS Biol (2005) 0.84
A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition. Proc Natl Acad Sci U S A (2009) 0.84
The expression pattern of FHL2 during mouse molar development. J Mol Histol (2012) 0.84
Protostylid: A case series. Contemp Clin Dent (2013) 0.83
Distinct developmental genetic mechanisms underlie convergently evolved tooth gain in sticklebacks. Development (2015) 0.83
The Prx1 homeobox gene is critical for molar tooth morphogenesis. J Dent Res (2006) 0.83
The similarity between human embryonic stem cell-derived epithelial cells and ameloblast-lineage cells. Int J Oral Sci (2013) 0.83
Leptin and vascular endothelial growth factor regulate angiogenesis in tooth germs. Histochem Cell Biol (2011) 0.83
Protogenin, a new member of the immunoglobulin superfamily, is implicated in the development of the mouse lower first molar. BMC Dev Biol (2010) 0.83
Towards unraveling the human tooth transcriptome: the dentome. PLoS One (2015) 0.82
A comparative examination of odontogenic gene expression in both toothed and toothless amniotes. J Exp Zool B Mol Dev Evol (2015) 0.82
Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development. J Mol Histol (2010) 0.81
BMP4 signaling mediates Zeb family in developing mouse tooth. Histochem Cell Biol (2012) 0.81
Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation. Hum Mol Genet (2013) 0.81
Manipulation of Fgf and Bmp signaling in teleost fishes suggests potential pathways for the evolutionary origin of multicuspid teeth. Evol Dev (2014) 0.81
An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis. J Biol Chem (2014) 0.81
An amelogenin mutation leads to disruption of the odontogenic apparatus and aberrant expression of Notch1. J Oral Pathol Med (2010) 0.81
The role of APCDD1 in epithelial rearrangement in tooth morphogenesis. Histochem Cell Biol (2015) 0.81
The role of preameloblast-conditioned medium in dental pulp regeneration. J Mol Histol (2013) 0.80
Cellular and molecular mechanisms of tooth root development. Development (2017) 0.80
Immunohistochemical localization of Pax6 in the developing tooth germ of mice. J Mol Histol (2014) 0.80
To What Extent is Primate Second Molar Enamel Occlusal Morphology Shaped by the Enamel-Dentine Junction? PLoS One (2015) 0.80
Expression of β-catenin and AXIN2 in ameloblastomas. Contemp Oncol (Pozn) (2013) 0.80
Prospective in (Primate) dental analysis through tooth 3D topographical quantification. PLoS One (2013) 0.80
Quantitative Genetics, Pleiotropy, and Morphological Integration in the Dentition of Papio hamadryas. Evol Biol (2009) 0.80
Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell (1993) 3.00
Localization of putative stem cells in dental epithelium and their association with Notch and FGF signaling. J Cell Biol (1999) 2.39
Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages. Cell (1995) 2.34
Integration of FGF and TWIST in calvarial bone and suture development. Development (2000) 2.15
Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene. Int J Dev Biol (1994) 2.12
Evolutionary modification of development in mammalian teeth: quantifying gene expression patterns and topography. Proc Natl Acad Sci U S A (2000) 2.09
FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development. Development (1998) 2.03
Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. Development (1999) 2.03
High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development. J Cell Biol (1994) 1.96
Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn (2000) 1.93
Tenascin is associated with chondrogenic and osteogenic differentiation in vivo and promotes chondrogenesis in vitro. J Cell Biol (1987) 1.80
The Tabby phenotype is caused by mutation in a mouse homologue of the EDA gene that reveals novel mouse and human exons and encodes a protein (ectodysplasin-A) with collagenous domains. Proc Natl Acad Sci U S A (1997) 1.77
The life history of an embryonic signaling center: BMP-4 induces p21 and is associated with apoptosis in the mouse tooth enamel knot. Development (1998) 1.77
Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn (1997) 1.76
The enamel knot as a signaling center in the developing mouse tooth. Mech Dev (1996) 1.71
Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev Dyn (1998) 1.68
Induced expression of syndecan in healing wounds. J Cell Biol (1991) 1.67
Gene defect in hypodontia: exclusion of EGF, EGFR, and FGF-3 as candidate genes. J Dent Res (1996) 1.66
FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci (2000) 1.64
Dependence of kidney morphogenesis on the expression of nerve growth factor receptor. Science (1991) 1.54
Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol (1998) 1.41
Tissue interactions in tooth development. Differentiation (1981) 1.39
Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development. J Biol Chem (1992) 1.39
Syndecan from embryonic tooth mesenchyme binds tenascin. J Biol Chem (1991) 1.37
Transferrin as a fetal growth factor: acquisition of responsiveness related to embryonic induction. Proc Natl Acad Sci U S A (1983) 1.35
Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development (1993) 1.35
Changes in the distribution of type IV collagen, laminin, proteoglycan, and fibronectin during mouse tooth development. Dev Biol (1981) 1.30
Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development (1995) 1.30
Apoptosis in the developing tooth: association with an embryonic signaling center and suppression by EGF and FGF-4. Development (1996) 1.25
TNF signaling via the ligand-receptor pair ectodysplasin and edar controls the function of epithelial signaling centers and is regulated by Wnt and activin during tooth organogenesis. Dev Biol (2001) 1.24
Expression of bone morphogenetic proteins and Msx genes during root formation. J Dent Res (2003) 1.22
Syndecan and tenascin expression is induced by epithelial-mesenchymal interactions in embryonic tooth mesenchyme. J Cell Biol (1989) 1.19
Characteristics of incisor-premolar hypodontia in families. J Dent Res (2001) 1.18
The anhidrotic ectodermal dysplasia gene (EDA) undergoes alternative splicing and encodes ectodysplasin-A with deletion mutations in collagenous repeats. Hum Mol Genet (1998) 1.18
Shh, Bmp-2, Bmp-4 and Fgf-8 are associated with initiation and patterning of mouse tongue papillae. Mech Dev (1999) 1.15
Identification of a nonsense mutation in the PAX9 gene in molar oligodontia. Eur J Hum Genet (2001) 1.14
Cusp patterning defect in Tabby mouse teeth and its partial rescue by FGF. Dev Biol (1999) 1.14
Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J Cell Biol (1995) 1.14
Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res (2005) 1.09
Primary structure, developmental expression, and immunolocalization of the murine laminin alpha4 chain. J Biol Chem (1997) 1.09
MSX1 gene is deleted in Wolf-Hirschhorn syndrome patients with oligodontia. J Dent Res (2003) 1.08
Fgfr mRNA isoforms in craniofacial bone development. Bone (2003) 1.08
The relationship between the keratocyst antigen (KCA) and keratin. J Oral Pathol (1986) 1.06
Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. J Cell Biol (1995) 1.06
Apoptosis in murine calvarial bone and suture development. Eur J Oral Sci (1999) 1.06
Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4. Development (1997) 1.04
Associations between transforming growth factor beta 1 RNA expression and epithelial-mesenchymal interactions during tooth morphogenesis. Development (1991) 1.02
Distribution of the transferrin receptor in normal human fibroblasts and fibrosarcoma cells. Int J Cancer (1983) 1.02
Signaling and subcellular localization of the TNF receptor Edar. Exp Cell Res (2001) 1.01
Ectodysplasin, a protein required for epithelial morphogenesis, is a novel TNF homologue and promotes cell-matrix adhesion. Mech Dev (1999) 1.00
Gene expression patterns associated with suppression of odontogenesis in mouse and vole diastema regions. Dev Genes Evol (1999) 1.00
Gene defect in hypodontia: exclusion of MSX1 and MSX2 as candidate genes. Hum Genet (1995) 0.99
Histological observations of teeth and peridental tissues in cleidocranial dysplasia imply increased activity of odontogenic epithelium and abnormal bone remodeling. J Craniofac Genet Dev Biol (1996) 0.98
Effect of surface processing on the attachment, orientation, and proliferation of human gingival fibroblasts on titanium. J Biomed Mater Res (1992) 0.98
Expression of syndecan gene is induced early, is transient, and correlates with changes in mesenchymal cell proliferation during tooth organogenesis. Dev Biol (1991) 0.98
92-kDa type IV collagenase and TIMP-3, but not 72-kDa type IV collagenase or TIMP-1 or TIMP-2, are highly expressed during mouse embryo implantation. Dev Dyn (1995) 0.96
Organogenesis in a defined medium supplemented with transferrin. Cell Differ (1981) 0.96
The epithelium-tooth interface--a basal lamina rich in laminin-5 and lacking other known laminin isoforms. J Dent Res (1998) 0.94
Activation of the Notch signaling pathway in response to pulp capping of rat molars. Eur J Oral Sci (2005) 0.93
Changes in the matrix proteins, fibronectin and collagen, during differentiation of mouse tooth germ. Dev Biol (1979) 0.92
Initiation of secondary cartilage in the mandible of the Syrian hamster in the absence of muscle function. Arch Oral Biol (1993) 0.91
Immunohistochemical localization of the matrix glycoproteins--tenascin and the ED-sequence-containing form of cellular fibronectin--in human permanent teeth and periodontal ligament. J Dent Res (1991) 0.90
Localization and quantitation of 125I-epidermal growth factor binding in mouse embryonic tooth and other embryonic tissues at different developmental stages. Dev Biol (1987) 0.90
Interference of tooth differentiation with interposed filters. Dev Biol (1977) 0.89
Basement membrane formation in transfilter tooth culture and its relation to odontoblast differentiation. Differentiation (1978) 0.89
Modulation of epithelial cell fate of the root in vitro. J Dent Res (2007) 0.87
Recessively inherited lower incisor hypodontia. J Med Genet (2001) 0.87
Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ (2010) 0.86
Role of transferrin in branching morphogenesis, growth and differentiation of the embryonic kidney. J Embryol Exp Morphol (1984) 0.86
Transferrin is required for early tooth morphogenesis. Differentiation (1984) 0.86
Comparison of expression of the msx-1, msx-2, BMP-2 and BMP-4 genes in the mouse upper diastemal and molar tooth primordia. Int J Dev Biol (1995) 0.85
Differentiation of odontogenic tissues in organ culture. Scand J Dent Res (1976) 0.83
High expression of 92-kDa type IV collagenase (gelatinase) in the osteoclast lineage during mouse development. Ann N Y Acad Sci (1994) 0.83
EGF receptor expression in mineralized tissues: an in situ hybridization and immunocytochemical investigation in rat and human mandibles. Connect Tissue Res (1995) 0.83
A graphical WWW-database on gene expression in tooth. Eur J Oral Sci (1998) 0.83
The gene defective in anhidrotic ectodermal dysplasia is expressed in the developing epithelium, neuroectoderm, thymus, and bone. J Histochem Cytochem (1998) 0.83
Expression of aquaporin isoforms during human and mouse tooth development. Arch Oral Biol (2004) 0.83
Immunohistochemical localization of epidermal growth factor receptors in human gingival epithelia. J Periodontal Res (1991) 0.83
Neurotrophin mRNA expression in the developing tooth suggests multiple roles in innervation and organogenesis. Dev Dyn (1997) 0.83
Exogenous fibronectin is not required for organogenesis in vitro. In Vitro (1983) 0.82
Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts. J Dent Res (1998) 0.82
In vitro inhibition of mouse odontoblast differentiation by vitamin A. Arch Oral Biol (1980) 0.82
Association between the expression of murine 72 kDa type IV collagenase by odontoblasts and basement membrane degradation during mouse tooth development. Arch Oral Biol (1992) 0.82
Sequential induction of syndecan, tenascin and cell proliferation associated with mesenchymal cell condensation during early tooth development. Differentiation (1992) 0.82
Comparison of the distribution patterns of tenascin and alkaline phosphatase in developing teeth, cartilage, and bone of rats and mice. Anat Rec (1990) 0.82
Novel Golgi protein, GoPro49, is a specific dental follicle marker. J Dent Res (2009) 0.82
Epithelial-mesenchymal interactions in murine organogenesis. Ciba Found Symp (1992) 0.81
Epidermal growth factor receptor as a mediator of developmental toxicity of dioxin in mouse embryonic teeth. Lab Invest (1998) 0.81
A lipophilic iron chelator can replace transferrin as a stimulator of cell proliferation and differentiation. J Cell Biol (1984) 0.81
Growth factors and tooth development. Int J Dev Biol (1989) 0.81
Detection of gelatinase B expression reveals osteoclastic bone resorption as a feature of early calvarial bone development. Bone (1997) 0.81
Inhibition of tooth germ differentiation in vitro by diazo-oxo-norleucine (DON). J Embryol Exp Morphol (1979) 0.81
Coordinated induction of cell proliferation and syndecan expression in dental mesenchyme by epithelium: evidence for diffusible signals. Dev Dyn (1992) 0.81
Two genes for missing teeth. Nat Genet (1996) 0.80
Tenascin-C in developing mouse teeth: expression of splice variants and stimulation by TGFbeta and FGF. Eur J Oral Sci (2001) 0.80
Role of the basement membrane in odontoblast differentiation. J Biol Buccale (1978) 0.80
Differential expression of the full-length and secreted truncated forms of EGF receptor during formation of dental tissues. Int J Dev Biol (1995) 0.80