PubRank

G K Whitfield

Author PubWeight™ 28.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The nuclear vitamin D receptor: biological and molecular regulatory properties revealed. J Bone Miner Res 1998 4.27
2 The polymorphic N terminus in human vitamin D receptor isoforms influences transcriptional activity by modulating interaction with transcription factor IIB. Mol Endocrinol 2000 1.58
3 Molecular nature of the vitamin D receptor and its role in regulation of gene expression. Rev Endocr Metab Disord 2001 1.55
4 The vitamin D hormone and its nuclear receptor: molecular actions and disease states. J Endocrinol 1997 1.53
5 Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor. J Biol Chem 1991 1.14
6 Phosphorylation of the human vitamin D receptor by protein kinase C. Biochemical and functional evaluation of the serine 51 recognition site. J Biol Chem 1993 1.14
7 Heterodimeric DNA binding by the vitamin D receptor and retinoid X receptors is enhanced by 1,25-dihydroxyvitamin D3 and inhibited by 9-cis-retinoic acid. Evidence for allosteric receptor interactions. J Biol Chem 1998 1.05
8 Phosphorylation of serine 208 in the human vitamin D receptor. The predominant amino acid phosphorylated by casein kinase II, in vitro, and identification as a significant phosphorylation site in intact cells. J Biol Chem 1993 1.03
9 Mutations in the 1,25-dihydroxyvitamin D3 receptor identifying C-terminal amino acids required for transcriptional activation that are functionally dissociated from hormone binding, heterodimeric DNA binding, and interaction with basal transcription factor IIB, in vitro. J Biol Chem 1997 0.99
10 The C-terminal region of the vitamin D receptor is essential to form a complex with a receptor auxiliary factor required for high affinity binding to the vitamin D-responsive element. Mol Endocrinol 1994 0.98
11 Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation. Proc Natl Acad Sci U S A 1996 0.98
12 Assignment of the gene for the beta subunit of thyroid-stimulating hormone to the short arm of human chromosome 1. Proc Natl Acad Sci U S A 1986 0.96
13 The T-box near the zinc fingers of the human vitamin D receptor is required for heterodimeric DNA binding and transactivation. Biochem Biophys Res Commun 1995 0.93
14 Characterization of unique DNA-binding and transcriptional-activation functions in the carboxyl-terminal extension of the zinc finger region in the human vitamin D receptor. Biochemistry 1999 0.91
15 Suppression of ANP gene transcription by liganded vitamin D receptor: involvement of specific receptor domains. Hypertension 1998 0.90
16 The glycoprotein alpha-subunit is critical for secretion and stability of the human thyrotropin beta-subunit. Mol Endocrinol 1988 0.89
17 Distinct retinoid X receptor activation function-2 residues mediate transactivation in homodimeric and vitamin D receptor heterodimeric contexts. J Mol Endocrinol 2001 0.88
18 New understanding of the molecular mechanism of receptor-mediated genomic actions of the vitamin D hormone. Bone 1995 0.88
19 Vitamin D receptor phosphorylation in transfected ROS 17/2.8 cells is localized to the N-terminal region of the hormone-binding domain. Mol Endocrinol 1991 0.86
20 The human thyrotropin beta-subunit gene differs in 5' structure from murine TSH-beta genes. DNA 1988 0.85
21 Two thyroid hormone regulated genes, the beta-subunits of nerve growth factor (NGFB) and thyroid stimulating hormone (TSHB), are located less than 310 kb apart in both human and mouse genomes. Genomics 1988 0.82
22 Receptor mediated genomic action of the 1,25(OH)2D3 hormone: expression of the human vitamin D receptor in E. coli. J Steroid Biochem Mol Biol 1995 0.79
23 Examination of the potential functional role of conserved cysteine residues in the hormone binding domain of the human 1,25-dihydroxyvitamin D3 receptor. J Biol Chem 1996 0.79
24 Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor. J Cell Biochem 1999 0.79
25 Expression of chorionic gonadotropin alpha- and beta-genes in normal and neoplastic human tissues: relationship to deoxyribonucleic acid structure. Endocrinology 1985 0.78
26 Evaluation of a putative vitamin D response element in the avian calcium binding protein gene. DNA Cell Biol 1992 0.76
27 Biochemical evidence for a 170-kilodalton, AF-2-dependent vitamin D receptor/retinoid X receptor coactivator that is highly expressed in osteoblasts. Biochem Biophys Res Commun 2000 0.75
28 Biosynthesis and secretion of follicle-stimulating hormone beta-subunit from ovine pituitary cultures: effect of 17 beta-estradiol treatment. Endocrinology 1984 0.75
29 Regulation of beta-chain mRNA of ovine follicle-stimulating hormone by 17 beta-estradiol. Mol Cell Biochem 1983 0.75