PubRank

D Broek

Author PubWeight™ 82.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol Cell Biol 1988 13.78
2 In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell 1985 11.63
3 DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase. Cell 1985 4.80
4 The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell 1987 4.74
5 Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav. Science 1998 4.41
6 Differential activation of yeast adenylate cyclase by wild-type and mutant RAS proteins. Cell 1985 4.23
7 RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor. Cell 1986 3.57
8 ras proteins can induce meiosis in Xenopus oocytes. Cell 1985 3.23
9 Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Mol Cell Biol 1987 2.45
10 Lck regulates Vav activation of members of the Rho family of GTPases. Mol Cell Biol 1997 1.96
11 Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol Cell Biol 1993 1.78
12 The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A 1989 1.73
13 Functional cloning of BUD5, a CDC25-related gene from S. cerevisiae that can suppress a dominant-negative RAS2 mutant. Cell 1991 1.56
14 Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding. J Biol Chem 2000 1.51
15 Studies of RAS function in the yeast Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol 1988 1.48
16 Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity. Proc Natl Acad Sci U S A 1994 1.44
17 EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival. Oncogene 2006 1.39
18 Two types of RAS mutants that dominantly interfere with activators of RAS. Mol Cell Biol 1994 1.36
19 Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 1992 1.23
20 Identification of residues of the H-ras protein critical for functional interaction with guanine nucleotide exchange factors. Mol Cell Biol 1994 1.09
21 Yeast cells can enter a quiescent state through G1, S, G2, or M phase of the cell cycle. Cancer Res 1993 1.02
22 Amino acid residues in the CDC25 guanine nucleotide exchange factor critical for interaction with Ras. Mol Cell Biol 1994 0.96
23 Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors. J Biol Chem 1996 0.94
24 Localization of the cellular expression pattern of cdc25NEF and ras in the juvenile rat brain. Brain Res Mol Brain Res 1993 0.93
25 The catalytic domain of the mouse sos1 gene product activates Ras proteins in vivo and in vitro. Oncogene 1993 0.91
26 Distinct subclasses of small GTPases interact with guanine nucleotide exchange factors in a similar manner. Mol Cell Biol 1998 0.88
27 Cloning and analysis of human cDNAs encoding a 140-kDa brain guanine nucleotide-exchange factor, Cdc25GEF, which regulates the function of Ras. Gene 1994 0.83
28 Biochemical analysis of regulation of Vav, a guanine-nucleotide exchange factor for Rho family of GTPases. Methods Enzymol 2000 0.81
29 Conservation and divergence of RAS protein function during evolution. Cold Spring Harb Symp Quant Biol 1985 0.80
30 Eukaryotic RAS proteins and yeast proteins with which they interact. Curr Top Microbiol Immunol 1989 0.78
31 Exploring the function of RAS oncogenes by studying the yeast Saccharomyces cerevisiae. Princess Takamatsu Symp 1986 0.77
32 A novel isoform of cytoplasmic actin that binds poly-L-proline. Biochem J 1986 0.77
33 Analysis of interaction between Ras and CDC25 guanine nucleotide exchange factor using yeast GAL4 two-hybrid system. Methods Enzymol 1995 0.77
34 Identification of a dominant-negative mutation in the yeast CDC25 guanine nucleotide exchange factor for Ras. Oncogene 1997 0.76
35 Identification and analysis of a DNA fragment from Saccharomyces kluyveri that can complement the loss of CDC25 function in Saccharomyces cerevisiae. Gene 1992 0.75
36 The adenylyl cyclase-encoding gene from Saccharomyces kluyveri. Gene 1991 0.75
37 Large scale in vivo risk assessment of bovine viral diarrhea virus (BVDV) transmission through transfer of bovine embryos produced via somatic cell nuclear transfer (SCNT). Theriogenology 2010 0.75