Published in Am J Pathol on May 01, 2000
Human hepatic stem cells from fetal and postnatal donors. J Exp Med (2007) 4.15
Liver stem cells and hepatocellular carcinoma. Hepatology (2009) 2.27
Insulin resistance and necroinflammation drives ductular reaction and epithelial-mesenchymal transition in chronic hepatitis C. Gut (2010) 1.59
Development of the bile ducts: essentials for the clinical hepatologist. J Hepatol (2012) 1.55
The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol (2007) 1.29
Analysis of liver repair mechanisms in Alagille syndrome and biliary atresia reveals a role for notch signaling. Am J Pathol (2007) 1.26
The immunobiology of cholangiocytes. Immunol Cell Biol (2008) 1.18
Epithelial-mesenchymal interactions in biliary diseases. Semin Liver Dis (2011) 1.11
Ductal plates in hepatic ductular reactions. Hypothesis and implications. III. Implications for liver pathology. Virchows Arch (2011) 0.99
Polycystic liver diseases. Dig Liver Dis (2010) 0.93
Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes. J Hepatol (2007) 0.92
Vascular biology of the biliary epithelium. J Gastroenterol Hepatol (2013) 0.91
Cysts of PRKCSH mutated polycystic liver disease patients lack hepatocystin but express Sec63p. Histochem Cell Biol (2008) 0.88
Fibrosis in autoimmune and cholestatic liver disease. Best Pract Res Clin Gastroenterol (2011) 0.87
Stem-like cells in human hepatoblastoma. J Histochem Cytochem (2004) 0.85
E-cadherin as a reliable cell surface marker for the identification of liver specific stem cells. J Mol Histol (2007) 0.82
Cirrhosis and autoimmune liver disease: Current understanding. World J Hepatol (2016) 0.81
Neural cell adhesion molecule and polysialic acid in ductular reaction: the puzzle is far from completed, but the picture is becoming more clear. Hepatology (2014) 0.79
Long-term culture of cholangiocytes from liver fibro-granulomatous lesions. BMC Gastroenterol (2006) 0.79
Revisiting Epithelial-to-Mesenchymal Transition in Liver Fibrosis: Clues for a Better Understanding of the "Reactive" Biliary Epithelial Phenotype. Stem Cells Int (2016) 0.78
Adult Hepatic Progenitor Cell Niche: How it affects the Progenitor Cell Fate. Middle East J Dig Dis (2014) 0.77
CD56 expression aids in the differential diagnosis of cholangiocarcinomas and benign cholangiocellular lesions. Virchows Arch (2006) 0.77
Autocrine and Paracrine Mechanisms Promoting Chemoresistance in Cholangiocarcinoma. Int J Mol Sci (2017) 0.75
Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment. Exp Biol Med (Maywood) (2016) 0.75
Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell (1996) 14.75
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (1990) 14.46
Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule. Proc Natl Acad Sci U S A (1983) 4.64
Cell adhesion molecules: implications for a molecular histology. Annu Rev Biochem (1991) 2.86
Origin, pattern, and mechanism of bile duct proliferation following biliary obstruction in the rat. Gastroenterology (1990) 2.79
Congenital diseases of intrahepatic bile ducts: variations on the theme "ductal plate malformation". Hepatology (1992) 2.59
Antibodies to a neural cell adhesion molecule disrupt histogenesis in cultured chick retinae. Nature (1980) 2.54
Review: assessment of cell proliferation in histological material. J Clin Pathol (1990) 2.41
Immunohistochemical study of the expression of a Mr 34,000 human epithelium-specific surface glycoprotein in normal and malignant tissues. Cancer Res (1987) 2.22
Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule. J Exp Med (1989) 2.17
Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am J Pathol (1993) 2.16
Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annu Rev Cell Dev Biol (1997) 2.01
Chronic active hepatitis associated with antiliver/kidney microsome antibody type 1: a second type of "autoimmune" hepatitis. Hepatology (1988) 1.79
Bcl-2 expression in adult and embryonic non-haematopoietic tissues. J Pathol (1993) 1.78
A neural cell adhesion molecule from human brain. Proc Natl Acad Sci U S A (1982) 1.77
Epithelial glycoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein. Proc Natl Acad Sci U S A (1990) 1.72
Ductular cell reaction in the liver in hepatic injury. J Mt Sinai Hosp N Y (1958) 1.69
The development of the intrahepatic bile ducts in man: a keratin-immunohistochemical study. Hepatology (1988) 1.59
Transforming growth factors beta 1 and beta 2 are differentially expressed in fibrotic liver disease. Am J Pathol (1991) 1.55
Alteration of the retinotectal map in Xenopus by antibodies to neural cell adhesion molecules. Proc Natl Acad Sci U S A (1984) 1.51
Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro. Hepatology (1994) 1.49
Differential contributions of Ng-CAM and N-CAM to cell adhesion in different neural regions. J Cell Biol (1986) 1.48
Ductular reaction in the liver. Pathol Res Pract (1995) 1.39
Immuno-isolation and culture of biliary epithelial cells from normal human liver. In Vitro Cell Dev Biol (1989) 1.37
Increased expression of intercellular adhesion molecule 1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology (1991) 1.35
LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase. J Clin Invest (1991) 1.34
Differential effects of nitric oxide synthase inhibitors on endotoxin-induced liver damage in rats. Gastroenterology (1997) 1.33
Immunohistochemical detection of bcl-2 protein in normal and pathological human liver. Am J Pathol (1994) 1.32
Neuroendocrine features of reactive bile ductules in cholestatic liver disease. Am J Pathol (1990) 1.28
The Walter Herbert Lecture. Control of cell motility and tumour invasion by extracellular matrix interactions. Br J Cancer (1992) 1.27
Detection of apoptosis and expression of apoptosis-related proteins during human intrahepatic bile duct development. Am J Pathol (1995) 1.21
Comparison of liver progenitor cells in human atypical ductular reactions with those seen in experimental models of liver injury. Hepatology (1998) 1.21
Basement membrane production by hepatocytes in chronic liver disease. Hepatology (1985) 1.21
Increased expression of interleukin-6 and tumor necrosis factor-alpha in pathologic biliary epithelial cells: in situ and culture study. Lab Invest (1998) 1.16
Phenotypic characterization of hepatic proliferation. Antigenic expression by proliferating epithelial cells in fetal liver, massive hepatic necrosis, and nodular transformation of the liver. Am J Pathol (1983) 1.12
Immunolocalization of OV-6, a putative progenitor cell marker in human fetal and diseased pediatric liver. Hepatology (1998) 1.12
PROLIFERATION OF BILE DUCTS IN CIRRHOSIS. Arch Pathol (1964) 1.05
Apoptosis is inhibited early in the dysplasia-carcinoma sequence of Barrett esophagus. Arch Surg (1997) 1.02
Metaplasia. An overview. Arch Pathol Lab Med (1984) 1.01
New concepts in biliary cirrhosis. Semin Liver Dis (1987) 1.01
Expression of blood group-related antigens in the intrahepatic biliary tree and hepatocytes in normal livers and various hepatobiliary diseases. Hepatology (1989) 1.00
Biliary epithelial cells from the liver of patients with primary biliary cirrhosis: isolation, characterization, and short-term culture. J Pathol (1990) 1.00
Development of intrahepatic bile ducts in humans. Possible role of laminin. Arch Pathol Lab Med (1990) 0.99
Immunohistochemical study on bile ductular proliferation in various hepatobiliary diseases. Liver (1986) 0.98
Hematopoietic stem cell markers are expressed by ductal plate and bile duct cells in developing human liver. Hepatology (1995) 0.96
HBsAg-induced hypertrophic smooth endoplasmic reticulum as a target for liver-kidney microsomal (LKM) antibodies. Clin Exp Immunol (1981) 0.94
Bcl-2 expression and its association with cell kinetics in human gastric carcinomas and intestinal metaplasia. J Cancer Res Clin Oncol (1995) 0.94
Increased expression of intercellular adhesion molecules in biliary atresia. Am J Pathol (1994) 0.94
Epithelial metaplasia and the second anatomy. Lancet (1986) 0.93
Cytokines in primary biliary cirrhosis. Semin Liver Dis (1997) 0.93
Ductular hepatocytes. Histol Histopathol (1995) 0.93
p53 but not bcl-2 is expressed by most cholangiocarcinomas: a study of 28 cases. Histopathology (1999) 0.92
Topographical immunohistochemical expression of bcl-2 protein in human liver lesions. Anticancer Res (1996) 0.90
Expression of blood group antigens including HLA markers in human adult liver. Tissue Antigens (1986) 0.89
Heparan sulfate proteoglycan expression in chronic cholestatic human liver diseases. Hepatology (1996) 0.87
Adhesion of neural cells to extracellular matrix constituents. Involvement of glycosaminoglycans and cell adhesion molecules. Brain Res (1988) 0.87
Immunohistochemical evaluation of Bcl-2 gene family expression in liver of hepatitis C and cirrhotic patients: a novel mechanism to explain the high incidence of hepatocarcinoma in cirrhotics. Am J Gastroenterol (1999) 0.87
Reactive human bile ductules express parathyroid hormone-related peptide. Histopathology (1993) 0.86
Expression and potential role of the extracellular matrix in hepatic ontogenesis: a review. Microsc Res Tech (1997) 0.86
Bile ductule formation in fetal, neonatal, and infant livers compared with extrahepatic biliary atresia. Hepatology (1996) 0.83
The apoptosis protector, bcl-2 protein, is downregulated in bile duct epithelial cells of human liver allografts. J Hepatol (1997) 0.81
Three-dimensional reconstruction of biliary pathways in primary biliary cirrhosis: a computer-assisted study. J Pathol (1987) 0.80
Reversed sequential double immunostaining. An indirect (antiglobulin) method for identifying cellular subsets using monoclonal antibodies of the same isotype. J Immunol Methods (1986) 0.80
Ductular structures in acute hepatitis with panacinar necrosis. J Pathol (1995) 0.79
Biliary epithelial cells: innocent victims or active participants in immune-mediated liver disease? J Lab Clin Med (1996) 0.77
A stereological study of intrahepatic bile ducts. 2. Bile duct proliferation in some pathological conditions. Acta Pathol Microbiol Scand A (1973) 0.77
The frequency and outcome of biliary atresia in the UK and Ireland. Lancet (2000) 2.78
Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver. J Immunol (1999) 2.61
Aberrant expression of HLA-DR antigens on bileduct epithelium in primary biliary cirrhosis: relevance to pathogenesis. Lancet (1984) 2.38
Selective decontamination of the digestive tract reduces gram-negative pulmonary colonization but not systemic endotoxemia in patients undergoing elective liver transplantation. Crit Care Med (1994) 2.21
Patterns of graft rejection following liver transplantation. J Hepatol (1990) 2.11
DNA synthesis in primary cultures of adult rat hepatocytes in a defined medium: effects of epidermal growth factor, insulin, glucagon, and cyclic-AMP. J Cell Physiol (1981) 1.87
Human hepatic stem-like cells isolated using c-kit or CD34 can differentiate into biliary epithelium. Gastroenterology (2001) 1.83
Acute polymyositis in an adult associated with Mycoplasma pneumoniae infection. Postgrad Med J (1990) 1.80
Wilson's disease with superimposed autoimmune features: report of two cases and review. J Gastroenterol Hepatol (2000) 1.70
Paracetamol induced hepatotoxicity. Arch Dis Child (2006) 1.67
Diversity of autoantibodies in primary biliary cirrhosis and chronic active hepatitis. Clin Exp Immunol (1984) 1.67
Effect of liver transplantation on QT interval prolongation and autonomic dysfunction in end-stage liver disease. Hepatology (1996) 1.59
ECG and echocardiographic diagnosis of pulmonary thromboembolism associated with central venous lines. Arch Dis Child (1995) 1.58
Anticentromere antibody in primary biliary cirrhosis. Ann Rheum Dis (1982) 1.53
Chronic renal failure following liver transplantation: a retrospective analysis. Transplantation (1998) 1.49
Hepatitis C in asymptomatic British blood donors with indeterminate seropositivity. BMJ (1994) 1.48
Prevalence of silent coeliac disease in atopics. Dig Liver Dis (2000) 1.48
Combined liver-kidney transplantation for primary hyperoxaluria type 1 in young children. Nephrol Dial Transplant (2001) 1.47
Thyroid hormone receptor expression in the "sick euthyroid" syndrome. Lancet (1990) 1.46
Developmental regulation of insulin-like growth factor II mRNA in different rat tissues. J Biol Chem (1986) 1.44
Intercellular adhesion molecule 1 on liver allografts during rejection. Lancet (1989) 1.44
Isolated liver transplant in infants with short bowel syndrome: insights into outcomes and prognostic factors. J Pediatr Gastroenterol Nutr (2009) 1.42
CD40 activation induces apoptosis in cultured human hepatocytes via induction of cell surface fas ligand expression and amplifies fas-mediated hepatocyte death during allograft rejection. J Exp Med (1999) 1.39
Antibodies to hepatitis C virus in autoimmune liver disease: evidence for geographical heterogeneity. Lancet (1991) 1.38
Immuno-isolation and culture of biliary epithelial cells from normal human liver. In Vitro Cell Dev Biol (1989) 1.37
Increased expression of intercellular adhesion molecule 1 on bile ducts in primary biliary cirrhosis and primary sclerosing cholangitis. Hepatology (1991) 1.35
Primary hepatic malignancy: the role of liver transplantation. Br J Surg (1990) 1.34
Immunolocalization of putative human liver progenitor cells in livers from patients with end-stage primary biliary cirrhosis and sclerosing cholangitis using the monoclonal antibody OV-6. Am J Pathol (1998) 1.33
Fulminant hepatitis B in infants born to anti-HBe hepatitis B carrier mothers. BMJ (1992) 1.32
Type 2 autoimmune hepatitis and hepatitis C virus infection. Lancet (1990) 1.30
Notch receptor expression in adult human liver: a possible role in bile duct formation and hepatic neovascularization. Hepatology (2001) 1.30
Increased severity and morbidity of acute hepatitis in drug abusers with simultaneously acquired hepatitis B and hepatitis D virus infections. Br Med J (Clin Res Ed) (1985) 1.29
Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J Pathol (1998) 1.29
Expression of the stem cell factor receptor c-kit in normal and diseased pediatric liver: identification of a human hepatic progenitor cell? Hepatology (1999) 1.28
Hepatocyte growth factor and macrophage inflammatory protein 1 beta: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells. Proc Natl Acad Sci U S A (1994) 1.25
Fas/Fas ligand interaction in human colorectal hepatic metastases: A mechanism of hepatocyte destruction to facilitate local tumor invasion. Am J Pathol (1999) 1.25
Biopsy findings in cases of rejection of liver allograft. J Clin Pathol (1985) 1.24
Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants. Transplantation (2001) 1.24
Stress fracture of the first rib. Am J Orthop (1966) 1.22
Bi-functional action of transforming growth factor-beta on DNA synthesis in early passage human fetal fibroblasts. J Cell Physiol (1986) 1.21
Basement membrane production by hepatocytes in chronic liver disease. Hepatology (1985) 1.21
Seamless management of biliary atresia in England and Wales (1999-2002). Lancet (2004) 1.19
Fluorescence immunohistochemical detection of hypoxic cells in spheroids and tumours. Br J Cancer (1987) 1.18
Quantitative assessment of canalicular bile formation in isolated hepatocyte couplets using microscopic optical planimetry. J Clin Invest (1989) 1.18
Sclerosing cholangitis associated with multifocal fibrosis: a case report. Gut (1992) 1.17
Recurrence of autoimmune hepatitis after liver transplantation. Transplantation (1999) 1.16
Transforming growth factor-beta induces human T lymphocyte migration in vitro. J Immunol (1991) 1.15
Proinflammatory cytokines inhibit secretion in rat bile duct epithelium. Gastroenterology (2001) 1.15
Expression and function of CXC and CC chemokines in human malignant liver tumors: a role for human monokine induced by gamma-interferon in lymphocyte recruitment to hepatocellular carcinoma. Hepatology (1999) 1.14
Successful liver transplantation in babies under 1 year. BMJ (1993) 1.14
The challenges and opportunities for transitional care research. Pediatr Transplant (2010) 1.14
Sex mismatch as a risk factor for chronic rejection of liver allografts. Lancet (1995) 1.13
Accuracy of staging in primary biliary cirrhosis. J Clin Pathol (1996) 1.13
Strategy for hepatoblastoma management: Transplant versus nontransplant surgery. J Pediatr Surg (2002) 1.12
Human intrahepatic biliary epithelial cells proliferate in vitro in response to human hepatocyte growth factor. J Clin Invest (1992) 1.12
Immunolocalization of OV-6, a putative progenitor cell marker in human fetal and diseased pediatric liver. Hepatology (1998) 1.12
Detection of circulating intercellular adhesion molecule-1 in chronic liver diseases. Hepatology (1992) 1.12
En block combined reduced-liver and small bowel transplants: from large donors to small children. Transplantation (2000) 1.10
Correlation between conventional disease activity measures in juvenile chronic arthritis. Ann Rheum Dis (1997) 1.10
Serious paracetamol poisoning and the results of liver transplantation. Gut (1994) 1.10
HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis. Gastroenterology (1994) 1.10
Timing, significance, and prognosis of late acute liver allograft rejection. Transplantation (1995) 1.09
Expression of co-stimulatory molecules by Kupffer cells in chronic hepatitis of hepatitis C virus etiology. Hepatology (1998) 1.09
A locus for asphyxiating thoracic dystrophy, ATD, maps to chromosome 15q13. J Med Genet (2003) 1.08
Is this really the current status of small bowel transplantation in the UK? Gut (2006) 1.08
Identification of somatomedin/insulin-like growth factor immunoreactive cells in the human fetus. Pediatr Res (1987) 1.07
CD40 activation-induced, Fas-dependent apoptosis and NF-kappaB/AP-1 signaling in human intrahepatic biliary epithelial cells. FASEB J (2001) 1.07
Dimethylnitrosamine-induced cirrhosis. Evidence for an immunological mechanism. J Hepatol (1989) 1.06
Liver and biliary problems in cystic fibrosis. Semin Liver Dis (1998) 1.06
Progress in treatment and outcome for children with neonatal haemochromatosis. Arch Dis Child Fetal Neonatal Ed (2003) 1.06
Endothelial activation and circulating vascular adhesion molecules in alcoholic liver disease. Hepatology (1994) 1.05
Liver transplantation for alcoholic liver disease: evaluation of a selection protocol. Hepatology (1997) 1.05
Stimulation of DNA synthesis in primary cultures of adult rat hepatocytes by rat platelet-associated substance(s). In Vitro (1982) 1.05
Is histological diagnosis of primary liver carcinomas with fibrous stroma reproducible among experts? J Clin Pathol (2009) 1.05
Transforming growth factor beta inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver. Biochem Biophys Res Commun (1987) 1.05
Novel application of a point mutation assay: evidence for transmission of hepatitis B viruses with precore mutations and their detection in infants with fulminant hepatitis B. J Med Virol (1994) 1.05
Risk of desmoid tumours after open and laparoscopic colectomy in patients with familial adenomatous polyposis. Br J Surg (2014) 1.04
Hepatitis C virus infection in the asymptomatic British blood donor. J Viral Hepat (1995) 1.04
Granulomatous mastitis--a rare cause of erythema nodosum. Postgrad Med J (1987) 1.04
Are parenchymal changes in early post-transplant biopsies related to preservation-reperfusion injury or rejection? Transplantation (2001) 1.04
Anti-nuclear antibodies of primary biliary cirrhosis recognize 78-92-kD and 96-100-kD proteins of nuclear bodies. Clin Exp Immunol (1991) 1.04
Early indicators of prognosis in fulminant hepatic failure: an assessment of the King's criteria. J Hepatol (1997) 1.04
Inhibition of interleukin 4-promoted CD23 production in human B lymphocytes by transforming growth factor-beta, interferons or anti-CD19 antibody is overriden on engaging CD40. Eur J Immunol (1991) 1.02
Effect of preoperative chemotherapy on liver resection for colorectal liver metastases. Eur J Surg Oncol (2007) 1.02