Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions.
|
Am J Surg Pathol
|
2001
|
6.30
|
2
|
Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis.
|
N Engl J Med
|
1993
|
6.13
|
3
|
Increased risk of cancer in the Peutz-Jeghers syndrome.
|
N Engl J Med
|
1987
|
4.55
|
4
|
Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins.
|
Lancet
|
1994
|
3.69
|
5
|
K-ras oncogene activation in adenocarcinoma of the human pancreas. A study of 82 carcinomas using a combination of mutant-enriched polymerase chain reaction analysis and allele-specific oligonucleotide hybridization.
|
Am J Pathol
|
1993
|
3.56
|
6
|
The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma.
|
Clin Cancer Res
|
2001
|
3.02
|
7
|
An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms.
|
J Pathol
|
1994
|
2.67
|
8
|
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression.
|
Cancer Res
|
1993
|
2.39
|
9
|
Impact of endoscopic biopsy surveillance of Barrett's oesophagus on pathological stage and clinical outcome of Barrett's carcinoma.
|
Gut
|
1998
|
2.38
|
10
|
K-ras oncogene activation in atypical alveolar hyperplasias of the human lung.
|
Cancer Res
|
1996
|
2.29
|
11
|
Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression.
|
Cancer Res
|
1998
|
2.23
|
12
|
Desmoid tumours in familial adenomatous polyposis.
|
Gut
|
1994
|
2.08
|
13
|
Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer.
|
Clin Cancer Res
|
2001
|
1.98
|
14
|
Detection of p53 overexpression in routinely paraffin-embedded tissue of human carcinomas using a novel target unmasking fluid.
|
Am J Pathol
|
1993
|
1.91
|
15
|
Incidence and clinical findings of benign, inflammatory disease in patients resected for presumed pancreatic head cancer.
|
Gastrointest Endosc
|
1997
|
1.88
|
16
|
Increased risk of thyroid and pancreatic carcinoma in familial adenomatous polyposis.
|
Gut
|
1993
|
1.85
|
17
|
Colorectal neoplasia in juvenile polyposis or juvenile polyps.
|
Arch Dis Child
|
1991
|
1.81
|
18
|
Overexpression of p53 protein in adenocarcinoma of the pancreas.
|
Am J Clin Pathol
|
1994
|
1.79
|
19
|
Prevalence and importance of pigmented ocular fundus lesions in Gardner's syndrome.
|
N Engl J Med
|
1987
|
1.76
|
20
|
Value of serology (ELISA and immunoblotting) for the diagnosis of Campylobacter pylori infection.
|
Digestion
|
1989
|
1.73
|
21
|
Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome.
|
Cancer Res
|
1998
|
1.73
|
22
|
Leptin is a growth factor for colonic epithelial cells.
|
Gastroenterology
|
2001
|
1.71
|
23
|
Genetic, immunohistochemical, and clinical features of medullary carcinoma of the pancreas: A newly described and characterized entity.
|
Am J Pathol
|
2000
|
1.69
|
24
|
Relationship between K-ras oncogene activation and smoking in adenocarcinoma of the human lung.
|
J Natl Cancer Inst
|
1991
|
1.64
|
25
|
Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis.
|
Endoscopy
|
2007
|
1.60
|
26
|
Rectal epithelial apoptosis in familial adenomatous polyposis patients treated with sulindac.
|
Gut
|
1999
|
1.59
|
27
|
Detection of K-ras mutations in mucinous pancreatic duct hyperplasia from a patient with a family history of pancreatic carcinoma.
|
Am J Pathol
|
1994
|
1.59
|
28
|
K-ras oncogene activation in lung adenocarcinomas from former smokers. Evidence that K-ras mutations are an early and irreversible event in the development of adenocarcinoma of the lung.
|
Cancer
|
1993
|
1.57
|
29
|
The potential diagnostic use of K-ras codon 12 and p53 alterations in brush cytology from the pancreatic head region.
|
J Pathol
|
1998
|
1.56
|
30
|
Value of brush cytology for dominant strictures in primary sclerosing cholangitis.
|
Endoscopy
|
1999
|
1.51
|
31
|
Rapid quantitative assessment of gastric corpus atrophy in tissue sections.
|
J Clin Pathol
|
2001
|
1.50
|
32
|
Classification of gastric carcinoma using the Goseki system provides prognostic information additional to TNM staging.
|
Cancer
|
1999
|
1.50
|
33
|
Peutz-Jeghers syndrome: 78-year follow-up of the original family.
|
Lancet
|
1999
|
1.46
|
34
|
A patient with seven primary tumors of the upper aerodigestive tract: the process of field cancerization versus distant monoclonal expansion.
|
Dis Esophagus
|
1997
|
1.43
|
35
|
Pancreatic adenocarcinomas with DNA replication errors (RER+) are associated with wild-type K-ras and characteristic histopathology. Poor differentiation, a syncytial growth pattern, and pushing borders suggest RER+.
|
Am J Pathol
|
1998
|
1.42
|
36
|
Geographical variance in the risk of gastric stump cancer: no increased risk in Japan?
|
Jpn J Cancer Res
|
1991
|
1.39
|
37
|
[Barrett esophagus and Barrett carcinoma].
|
Ned Tijdschr Geneeskd
|
1997
|
1.39
|
38
|
Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families.
|
Hum Mutat
|
1999
|
1.39
|
39
|
Familial pancreatic cancer.
|
Ann Oncol
|
1999
|
1.33
|
40
|
The role of nonsteroidal anti-inflammatory drugs in colorectal cancer prevention.
|
Eur J Cancer
|
1995
|
1.32
|
41
|
Small cell carcinoma of the gallbladder: a clinicopathologic, immunohistochemical, and molecular pathology study of 12 cases.
|
Am J Surg Pathol
|
2001
|
1.30
|
42
|
NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps.
|
Oncogene
|
2001
|
1.28
|
43
|
Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis.
|
Gut
|
1995
|
1.26
|
44
|
The value of screening and central registration of families with familial adenomatous polyposis. A study of 82 families in The Netherlands.
|
Dis Colon Rectum
|
1990
|
1.25
|
45
|
The tumour spectrum in hereditary non-polyposis colorectal cancer: a study of 24 kindreds in the Netherlands.
|
Int J Cancer
|
1990
|
1.24
|
46
|
Risk of hepatoblastoma in familial adenomatous polyposis.
|
J Pediatr
|
1991
|
1.20
|
47
|
Pancreatic mucinous cystic neoplasms with sarcomatous stroma: molecular evidence for monoclonal origin with subsequent divergence of the epithelial and sarcomatous components.
|
Mod Pathol
|
2000
|
1.18
|
48
|
Tumor-suppressor genes in pancreatic cancer.
|
J Hepatobiliary Pancreat Surg
|
1998
|
1.17
|
49
|
Adenocarcinoma arising within a tailgut cyst: clinicopathological description and follow up of an unusual case.
|
J Clin Pathol
|
1999
|
1.17
|
50
|
Survival after pancreaticoduodenectomy for periampullary adenocarcinoma: an update.
|
Eur J Surg Oncol
|
2001
|
1.16
|
51
|
Neoadjuvant chemoradiation followed by surgery versus surgery alone for patients with adenocarcinoma or squamous cell carcinoma of the esophagus (CROSS).
|
BMC Surg
|
2008
|
1.15
|
52
|
Meta-analysis of the risk of gastric stump cancer: detection of high risk patient subsets for stomach cancer after remote partial gastrectomy for benign conditions.
|
Cancer Res
|
1990
|
1.14
|
53
|
Prognostic value of Laurén classification and c-erbB-2 oncogene overexpression in adenocarcinoma of the esophagus and gastroesophageal junction.
|
Ann Surg Oncol
|
1999
|
1.13
|
54
|
Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.
|
Gastroenterology
|
1996
|
1.13
|
55
|
K-ras oncogene mutations in osteoclast-like giant cell tumors of the pancreas and liver: genetic evidence to support origin from the duct epithelium.
|
Am J Surg Pathol
|
1998
|
1.12
|
56
|
Microsatellite instability and expression of hMLH-1 and hMSH-2 in sebaceous gland carcinomas as markers for Muir-Torre syndrome.
|
Clin Cancer Res
|
2000
|
1.12
|
57
|
The value of p53 and Ki67 as markers for tumour progression in the Barrett's dysplasia-carcinoma sequence.
|
Surg Oncol
|
1995
|
1.11
|
58
|
Local resection or pancreaticoduodenectomy for villous adenoma of the ampulla of Vater diagnosed before operation.
|
Br J Surg
|
1997
|
1.11
|
59
|
Pathology of incipient pancreatic cancer.
|
Ann Oncol
|
1999
|
1.10
|
60
|
Clinical decision making in Barrett's oesophagus can be supported by computerized immunoquantitation and morphometry of features associated with proliferation and differentiation.
|
J Pathol
|
1998
|
1.09
|
61
|
Clinical heterogeneity of familial colorectal cancer and its influence on screening protocols.
|
Gut
|
1994
|
1.09
|
62
|
Pathology of early invasive adenocarcinoma of the esophagus or esophagogastric junction: implications for therapeutic decision making.
|
Cancer
|
2000
|
1.08
|
63
|
Value of combined phenotypic markers in identifying inheritance of familial adenomatous polyposis.
|
Gut
|
1991
|
1.07
|
64
|
Endoscopic screening for malignancy in the gastric remnant: the clinical significance of dysplasia in gastric mucosa.
|
J Clin Pathol
|
1984
|
1.07
|
65
|
Multivariate analysis of the risk of stomach cancer after ulcer surgery in an Amsterdam cohort of postgastrectomy patients.
|
Am J Epidemiol
|
1991
|
1.06
|
66
|
Multiple hyperplastic polyps in the stomach: evidence for clonality and neoplastic potential.
|
Gastroenterology
|
1997
|
1.05
|
67
|
Cancer risk in collagenous colitis.
|
Inflamm Bowel Dis
|
1999
|
1.05
|
68
|
Hereditary nonpolyposis colorectal cancer: results of long-term surveillance in 50 families.
|
Eur J Cancer
|
1995
|
1.04
|
69
|
Overexpression of the p53 tumor suppressor gene product in primary lung adenocarcinomas is associated with cigarette smoking.
|
Am J Surg Pathol
|
1993
|
1.04
|
70
|
Influence of oral 15(R)-15-methyl prostaglandin E2 on human gastric mucosa. A light microscopic, cell kinetic, and ultrastructural study.
|
Gastroenterology
|
1986
|
1.04
|
71
|
Computerized quantitative pathology for the grading of dysplasia in surveillance biopsies of Barrett's oesophagus.
|
J Pathol
|
2000
|
1.01
|
72
|
CD44 splice variants as prognostic markers in colorectal cancer.
|
Scand J Gastroenterol
|
1998
|
0.99
|
73
|
Potential false-positive results with antigen enhancement for immunohistochemistry of the p53 gene product in colorectal neoplasms.
|
J Pathol
|
1996
|
0.98
|
74
|
Immunostaining of chain-specific keratins on formalin-fixed, paraffin-embedded tissues: a comparison of various antigen retrieval systems using microwave heating and proteolytic pre-treatments.
|
J Histochem Cytochem
|
1995
|
0.98
|
75
|
Clinical and pathological associations with p53 tumour-suppressor gene mutations and expression of p21WAF1/Cip1 in colorectal carcinoma.
|
Br J Cancer
|
1996
|
0.97
|
76
|
Occurrence of non-gastric cancer in the digestive tract after remote partial gastrectomy: analysis of an Amsterdam cohort.
|
Int J Cancer
|
1990
|
0.96
|
77
|
CD44 glycoproteins in colorectal cancer: expression, function, and prognostic value.
|
Adv Cancer Res
|
2000
|
0.96
|
78
|
APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis.
|
Gut
|
1997
|
0.95
|
79
|
Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.
|
J Clin Pathol
|
2001
|
0.95
|
80
|
Gangliocytic paraganglioma of the appendix.
|
Histopathology
|
2000
|
0.95
|
81
|
Chronology of p53 protein accumulation in gastric carcinogenesis.
|
Gut
|
1995
|
0.95
|
82
|
p53 alterations in atypical alveolar hyperplasia of the human lung.
|
Hum Pathol
|
1998
|
0.95
|
83
|
K-ras mutations in the duodenal fluid of patients with pancreatic carcinoma.
|
Cancer
|
1998
|
0.95
|
84
|
Carcinogenesis after remote peptic ulcer surgery: the long-term prognosis of partial gastrectomy.
|
Scand J Gastroenterol Suppl
|
1995
|
0.95
|
85
|
Clinical value of K-ras codon 12 analysis and endobiliary brush cytology for the diagnosis of malignant extrahepatic bile duct stenosis.
|
Clin Cancer Res
|
1999
|
0.94
|
86
|
Carcinoid tumors of the extrahepatic bile ducts: a study of seven cases.
|
Am J Surg Pathol
|
2000
|
0.94
|
87
|
Reproducibility of p53 and Ki-67 immunoquantitation in Barrett's esophagus.
|
Anal Quant Cytol Histol
|
1997
|
0.94
|
88
|
The relationship of quantitative nuclear morphology to molecular genetic alterations in the adenoma-carcinoma sequence of the large bowel.
|
Am J Pathol
|
1992
|
0.94
|
89
|
Helicobacter pylori and Epstein-Barr virus infection and the p53 tumour suppressor pathway in gastric stump cancer compared with carcinoma in the non-operated stomach.
|
J Clin Pathol
|
1998
|
0.93
|
90
|
Pyloric gland adenoma of the main pancreatic duct.
|
Am J Surg Pathol
|
1999
|
0.91
|
91
|
Atypical melanocytic proliferation associated with squamous cell carcinoma in situ of the esophagus.
|
Virchows Arch
|
2000
|
0.91
|
92
|
The operated stomach: a premalignant condition? A prospective endoscopic follow-up study.
|
Scand J Gastroenterol
|
1984
|
0.90
|
93
|
Evaluation of p53 protein expression as a marker for long-term prognosis in colorectal carcinoma.
|
Br J Cancer
|
1995
|
0.90
|
94
|
Partial gastrectomy: a risk factor for carcinoma of the pancreas?
|
Hum Pathol
|
1987
|
0.90
|
95
|
Immunohistochemical labeling for the Dpc4 gene product is a specific marker for adenocarcinoma in biopsy specimens of the pancreas and bile duct.
|
Am J Clin Pathol
|
2001
|
0.89
|
96
|
Clinical significance of K-ras oncogene activation in ampullary neoplasms.
|
J Clin Pathol
|
1996
|
0.88
|
97
|
Molecular markers for diagnostic cytology of neoplasms in the head region of the pancreas: mutation of K-ras and overexpression of the p53 protein product.
|
J Clin Pathol
|
1995
|
0.88
|
98
|
Prognostic value of cell proliferation (Ki-67 antigen) and nuclear DNA content in clinically resectable, distal bile duct carcinoma.
|
Ann Surg Oncol
|
1998
|
0.87
|
99
|
Molecular analysis of sulindac-resistant adenomas in familial adenomatous polyposis.
|
Clin Cancer Res
|
2001
|
0.87
|
100
|
Can K-ras codon 12 mutations be used to distinguish benign bile duct proliferations from metastases in the liver? A molecular analysis of 101 liver lesions from 93 patients.
|
Am J Pathol
|
1997
|
0.87
|
101
|
Molecular evidence of field cancerization in a patient with 7 tumors of the aerodigestive tract.
|
Hum Pathol
|
2000
|
0.87
|
102
|
Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.
|
J Pathol
|
2001
|
0.87
|
103
|
Heterotopic gastric mucosa of the cervical esophagus: a case of high-grade dysplasia treated with argon plasma coagulation and a case of adenocarcinoma.
|
Gastrointest Endosc
|
2001
|
0.86
|
104
|
Local excision and mucosal advancement for anorectal ulceration in patients infected with human immunodeficiency virus.
|
Br J Surg
|
1995
|
0.86
|
105
|
Recent developments in hereditary nonpolyposis colorectal cancer.
|
Scand J Gastroenterol Suppl
|
1996
|
0.85
|
106
|
Intrauterine fetal death due to Farber disease: case report.
|
Pediatr Dev Pathol
|
2000
|
0.84
|
107
|
Jan Peutz, Harold Jeghers and a remarkable combination of polyposis and pigmentation of the skin and mucous membranes.
|
Fam Cancer
|
2001
|
0.83
|
108
|
Occult radiopaque jaw lesions in familial adenomatous polyposis coli and hereditary nonpolyposis colorectal cancer.
|
Gastroenterology
|
1987
|
0.83
|
109
|
Difference in expression of CD44 splice variants between proximal and distal adenocarcinoma of the large bowel.
|
Br J Surg
|
1995
|
0.83
|
110
|
Intestinal and pancreatic metaplasia at the esophagogastric junction in patients without Barrett's esophagus.
|
Am J Gastroenterol
|
2000
|
0.82
|
111
|
Treatment of Helicobacter pylori infection favourably affects gastric mucosal superoxide dismutases.
|
Gut
|
1997
|
0.82
|
112
|
K-ras mutations in gastric stump carcinomas and in carcinomas from the non-operated stomach.
|
Hepatogastroenterology
|
1999
|
0.82
|
113
|
Clinical applications of detecting dysfunctional p53 tumor suppressor protein.
|
Histol Histopathol
|
1999
|
0.81
|
114
|
Prospective analysis of the diagnostic yield of extended en bloc resection for adenocarcinoma of the oesophagus or gastric cardia.
|
Br J Surg
|
2001
|
0.81
|
115
|
Gastric carcinoma: clinical, pathogenic, and molecular aspects.
|
QJM
|
1997
|
0.81
|
116
|
p53 and CD44 as clinical markers of tumour progression in colorectal carcinogenesis.
|
Histochem J
|
1997
|
0.80
|
117
|
Molecular alterations in early gastric carcinomas. No apparent correlation with Helicobacter pylori status.
|
Am J Clin Pathol
|
1999
|
0.80
|
118
|
Squamous cell carcinoma in Barrett's esophagus: field effect versus metastasis.
|
Dis Esophagus
|
2012
|
0.80
|
119
|
Barrett oesophagus and adenocarcinoma: an overview of epidemiologic, conceptual and clinical issues.
|
Scand J Gastroenterol Suppl
|
2001
|
0.80
|
120
|
Laparoscopic ultrasonography of abdominal lymph nodes: correlation with pathologic findings.
|
J Ultrasound Med
|
1998
|
0.80
|
121
|
Mutational analysis of the P16-binding domain of cyclin-dependent kinase 4 in tumors in the head region of the pancreas.
|
Pancreas
|
1998
|
0.79
|
122
|
Absence of ras gene mutations in early gastric carcinomas.
|
Gut
|
1995
|
0.79
|
123
|
Long-term prognosis after partial gastrectomy for benign conditions. Survival and smoking-related death of 2633 Amsterdam postgastrectomy patients followed up since surgery between 1931 and 1960.
|
Gastroenterology
|
1991
|
0.78
|
124
|
Micrometastases in bone marrow of patients with suspected pancreatic and ampullary cancer.
|
Eur J Surg Oncol
|
2001
|
0.78
|
125
|
Molecular diagnosis of cancer and micrometastases.
|
Adv Anat Pathol
|
1998
|
0.78
|
126
|
Diagnostic p53 immunostaining of endobiliary brush cytology: preoperative cytology compared with the surgical specimen.
|
Cancer
|
1999
|
0.78
|
127
|
Expression of HLA-DQ antigens in the small-intestinal mucosa of patients with coeliac disease.
|
Scand J Gastroenterol
|
1991
|
0.78
|
128
|
DNA quantitation of distal bile duct carcinoma measured by image and flow cytometry.
|
Anal Quant Cytol Histol
|
1999
|
0.77
|
129
|
Comprehensive Cancer Centre Amsterdam Barrett Advisory Committee: first results.
|
Neth J Med
|
2001
|
0.77
|
130
|
Expression of receptors for gut peptides in human pancreatic adenocarcinoma and tumour-free pancreas.
|
Br J Cancer
|
1997
|
0.77
|
131
|
p21(Waf1/Cip1) expression and the p53/MDM2 feedback loop in gastric carcinogenesis.
|
J Pathol
|
1999
|
0.77
|
132
|
Peutz-Jeghers polyps, dysplasia, and K-ras codon 12 mutations.
|
Gut
|
1997
|
0.77
|
133
|
Cell proliferation kinetics in the gastric remnant.
|
Eur J Cancer Clin Oncol
|
1985
|
0.77
|
134
|
Remote partial gastrectomy as a risk factor for pancreatic cancer: potential for preventive strategies.
|
Ann Oncol
|
1999
|
0.77
|
135
|
Short-term results of gastrectomy with Roux-en-Y or Billroth II anastomosis for peptic ulcer. A prospective comparative study.
|
Hepatogastroenterology
|
1992
|
0.76
|
136
|
p53 expression as a prognostic determinant in resected distal bile duct carcinoma.
|
Eur J Surg Oncol
|
1999
|
0.76
|
137
|
Diagnostic and prognostic value of incidence of K-ras codon 12 mutations in resected distal bile duct carcinoma.
|
J Surg Oncol
|
1998
|
0.76
|
138
|
No evidence for c-erbB-2 overexpression in gastric carcinogenesis.
|
Histopathology
|
1998
|
0.75
|
139
|
Expression of somatostatin receptors in human pancreatic tumor.
|
Pancreas
|
1998
|
0.75
|
140
|
Consequences of gastric surgery for benign conditions: an overview.
|
Hepatogastroenterology
|
1988
|
0.75
|
141
|
[Cystadenomas with ovarian stroma in liver and pancreas: indications of embryonic migration of the gonadal epithelium].
|
Ned Tijdschr Geneeskd
|
2004
|
0.75
|
142
|
Partial gastrectomy: a risk factor for pancreatic cancer?
|
J Natl Cancer Inst
|
1986
|
0.75
|
143
|
[Is the operated stomach a precancerous condition?].
|
ZFA (Stuttgart)
|
1983
|
0.75
|
144
|
[The importance of clinical characteristics in familial adenomatous polyposis].
|
Ned Tijdschr Geneeskd
|
1988
|
0.75
|
145
|
[Carcinoma with premalignant changes in stomach biopsies of patients having undergone a stomach operation more than 15 years ago].
|
Ned Tijdschr Geneeskd
|
1984
|
0.75
|
146
|
Contributions of the molecular biologist in gastrointestinal cancer and precancer screening: current possibilities and future prospects.
|
Gastrointest Endosc Clin N Am
|
1997
|
0.75
|
147
|
Pancreatic cancer--more familial than you thought.
|
Anal Cell Pathol
|
1999
|
0.75
|
148
|
Role of tumor markers and mutations in cells and pancreatic juice in the diagnosis of pancreatic cancer.
|
Ann Oncol
|
1999
|
0.75
|
149
|
[Carcinoma of the gastric stump].
|
Ned Tijdschr Geneeskd
|
1983
|
0.75
|
150
|
Molecular and phenotypic markers of hamartomatous polyposis syndromes in the gastrointestinal tract.
|
Hepatogastroenterology
|
1999
|
0.75
|
151
|
[Mortality from stomach carcinoma following stomach surgery for benign disorders; analysis of an Amsterdam cohort].
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