Effects of mobile buffers on facilitation: experimental and computational studies.

PubWeight™: 1.33‹?› | Rank: Top 10%

🔗 View Article (PMC 1300864)

Published in Biophys J on June 01, 2000

Authors

Y Tang1, T Schlumpberger, T Kim, M Lueker, R S Zucker

Author Affiliations

1: Molecular and Cell Biology Department, Neurobiology Division, University of California, Berkeley 94720, USA.

Articles citing this

Transmitter release modulation by intracellular Ca2+ buffers in facilitating and depressing nerve terminals of pyramidal cells in layer 2/3 of the rat neocortex indicates a target cell-specific difference in presynaptic calcium dynamics. J Physiol (2001) 2.63

Short-term forms of presynaptic plasticity. Curr Opin Neurobiol (2011) 1.90

Ca(2+)-dependent enhancement of release by subthreshold somatic depolarization. Nat Neurosci (2010) 1.49

Spatiotemporal features of Ca2+ buffering and diffusion in atrial cardiac myocytes with inhibited sarcoplasmic reticulum. Biophys J (2002) 1.47

Facilitation through buffer saturation: constraints on endogenous buffering properties. Biophys J (2004) 1.39

A general model of synaptic transmission and short-term plasticity. Neuron (2009) 1.37

Heterogeneous presynaptic release probabilities: functional relevance for short-term plasticity. Biophys J (2003) 1.25

Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum. PLoS Comput Biol (2010) 1.23

Diffusional mobility of parvalbumin in spiny dendrites of cerebellar Purkinje neurons quantified by fluorescence recovery after photobleaching. Biophys J (2003) 1.17

A limited contribution of Ca2+ current facilitation to paired-pulse facilitation of transmitter release at the rat calyx of Held. J Physiol (2008) 1.09

Consequences of molecular-level Ca2+ channel and synaptic vesicle colocalization for the Ca2+ microdomain and neurotransmitter exocytosis: a monte carlo study. Biophys J (2004) 1.06

Developmental decrease in synaptic facilitation at the mouse hippocampal mossy fibre synapse. J Physiol (2003) 1.04

Paired pulse facilitation of corticogeniculate EPSCs in the dorsal lateral geniculate nucleus of the rat investigated in vitro. J Physiol (2002) 1.00

Presynaptic frequency- and pattern-dependent filtering. J Comput Neurosci (2003) 0.94

Local signaling with molecular diffusion as a decoder of Ca2+ signals in synaptic plasticity. Mol Syst Biol (2005) 0.93

Neurosteroid-induced enhancement of short-term facilitation involves a component downstream from presynaptic calcium in hippocampal slices. J Physiol (2006) 0.91

Mechanisms underlying short-term modulation of transmitter release by presynaptic depolarization. J Physiol (2009) 0.91

Increased Ca2+ influx through Na+/Ca2+ exchanger during long-term facilitation at crayfish neuromuscular junctions. J Physiol (2007) 0.90

The diverse functions of short-term plasticity components in synaptic computations. Commun Integr Biol (2011) 0.89

Short-term facilitation modulates size and timing of the synaptic response at the inner hair cell ribbon synapse. J Neurosci (2011) 0.89

Photolysis-induced suppression of inhibition in rat hippocampal CA1 pyramidal neurons. J Physiol (2001) 0.86

Protein kinase C acts as a molecular detector of firing patterns to mediate sensory gating in Aplysia. Nat Neurosci (2012) 0.83

Increased Ca2+ buffering enhances Ca2+-dependent process. J Physiol (2001) 0.81

Modeling of quantal neurotransmitter release kinetics in the presence of fixed and mobile calcium buffers. J Comput Neurosci (2008) 0.81

New insights into short-term synaptic facilitation at the frog neuromuscular junction. J Neurophysiol (2014) 0.78

Hyperosmolarity reduces facilitation by a Ca(2+)-independent mechanism at the lobster neuromuscular junction: possible depletion of the releasable pool. J Physiol (2001) 0.78

The facilitated probability of quantal secretion within an array of calcium channels of an active zone at the amphibian neuromuscular junction. Biophys J (2004) 0.76

Effects of increasing Ca2+ channel-vesicle separation on facilitation at the crayfish inhibitory neuromuscular junction. Neuroscience (2008) 0.75

Regulation of exocytic mode in hippocampal neurons by intra-bouton calcium concentration. J Physiol (2010) 0.75

Articles cited by this

A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem (1985) 90.20

A further study of the statistical composition on the end-plate potential. J Physiol (1955) 19.64

The role of calcium in neuromuscular facilitation. J Physiol (1968) 9.35

Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science (1992) 6.72

Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse. Biophys J (1981) 5.19

Anomalous diffusion due to obstacles: a Monte Carlo study. Biophys J (1994) 5.10

Microdomains of high calcium concentration in a presynaptic terminal. Science (1992) 5.09

Calcium dependence of the rate of exocytosis in a synaptic terminal. Nature (1994) 4.77

Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse. J Neurosci (1991) 4.08

Effects of rapid buffers on Ca2+ diffusion and Ca2+ oscillations. Biophys J (1994) 4.07

Linearized buffered Ca2+ diffusion in microdomains and its implications for calculation of [Ca2+] at the mouth of a calcium channel. J Neurosci (1997) 3.28

Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release. Neuron (1993) 3.07

Localization of calcium signals by a mobile calcium buffer in frog saccular hair cells. J Neurosci (1994) 2.96

Usefulness and limitations of linear approximations to the understanding of Ca++ signals. Cell Calcium (1999) 2.84

Calcium- and activity-dependent synaptic plasticity. Curr Opin Neurobiol (1999) 2.59

Determinants of the time course of facilitation at the granule cell to Purkinje cell synapse. J Neurosci (1996) 2.54

Mitochondrial involvement in post-tetanic potentiation of synaptic transmission. Neuron (1997) 2.35

Time courses of calcium and calcium-bound buffers following calcium influx in a model cell. Biophys J (1993) 2.35

Ca2+ binding kinetics of fura-2 and azo-1 from temperature-jump relaxation measurements. Biophys J (1988) 2.24

Time course of transmitter release calculated from simulations of a calcium diffusion model. Biophys J (1992) 2.16

Monte Carlo analysis of obstructed diffusion in three dimensions: application to molecular diffusion in organelles. Biophys J (1998) 2.00

Kinetic studies of Ca2+ binding and Ca2+ clearance in the cytosol of adrenal chromaffin cells. Biophys J (1997) 1.99

Residual Ca2+ and short-term synaptic plasticity. Nature (1994) 1.95

Delayed release of neurotransmitter from cerebellar granule cells. J Neurosci (1998) 1.93

T-jump study of calcium binding kinetics of calcium chelators. Cell Calcium (1997) 1.92

Ca2+ currents in cerebral artery smooth muscle cells of rat at physiological Ca2+ concentrations. J Gen Physiol (1996) 1.90

A two-step model of secretion control in neuroendocrine cells. Pflugers Arch (1993) 1.64

Characteristics of crayfish neuromuscular facilitation and their calcium dependence. J Physiol (1974) 1.61

Low mobility of the Ca2+ buffers in axons of cultured Aplysia neurons. Neuron (1997) 1.57

The effect of reduced calcium on quantal unit current and release at the crayfish neuromuscular junction. Pflugers Arch (1981) 1.55

A quantitative analysis of presynaptic calcium dynamics that contribute to short-term enhancement. J Neurosci (1995) 1.55

Single-domain/bound calcium hypothesis of transmitter release and facilitation. J Neurophysiol (1996) 1.55

Calcium in motor nerve terminals associated with posttetanic potentiation. J Neurosci (1989) 1.47

A quantitative measurement of the dependence of short-term synaptic enhancement on presynaptic residual calcium. J Neurosci (1994) 1.44

Ca2+ cooperativity in neurosecretion measured using photolabile Ca2+ chelators. J Neurophysiol (1994) 1.31

Effects of membrane potential and temperature on the excitatory post-synaptic current in the crayfish muscle. J Physiol (1978) 1.28

Simultaneous measurement of intracellular Ca2+ and asynchronous transmitter release from the same crayfish bouton. J Physiol (1997) 1.25

Identification of a calcium-binding, brain specific protein in the axoplasm of squid giant axons. J Neurochem (1973) 1.24

Organization and synaptic physiology of crustacean neuromuscular systems. Prog Neurobiol (1976) 1.24

Effects of intra-axonal injection of Ca2+ buffers on evoked release and on facilitation in the crayfish neuromuscular junction. Neurosci Lett (1991) 1.23

Homosynaptic facilitation of transmitter release in crayfish is not affected by mobile calcium chelators: implications for the residual ionized calcium hypothesis from electrophysiological and computational analyses. J Neurophysiol (1994) 1.13

Diffusion barriers limit the effect of mobile calcium buffers on exocytosis of large dense cored vesicles. Biophys J (1999) 1.12

Synaptic structural complexity as a factor enhancing probability of calcium-mediated transmitter release. J Neurophysiol (1996) 1.11

Synaptic differentiation of a single motor neuron: conjoint definition of transmitter release, presynaptic calcium signals, and ultrastructure. J Neurosci (1995) 1.08

Presynaptic calcium and serotonin-mediated enhancement of transmitter release at crayfish neuromuscular junction. J Neurosci (1991) 1.06

Modeling study of the effects of overlapping Ca2+ microdomains on neurotransmitter release. Biophys J (1999) 1.03

Ca2+ and the regulation of neurotransmitter secretion. Curr Opin Neurobiol (1997) 1.02

Comparison of the enhanced steady-state diffusion of calcium by calbindin-D9K and calmodulin: possible importance in intestinal calcium absorption. Cell Calcium (1989) 0.96

Residual free calcium is not responsible for facilitation of neurotransmitter release. Proc Natl Acad Sci U S A (1993) 0.94

Calcium dependence of quantal release triggered by graded depolarization pulses to nerve terminals on crayfish and frog muscle. Pflugers Arch (1989) 0.93

Posttetanic potentiation at the crayfish neuromuscular junction is dependent on both intracellular calcium and sodium ion accumulation. J Neurosci (1992) 0.91

Recombinant scinderin enhances exocytosis, an effect blocked by two scinderin-derived actin-binding peptides and PIP2. Neuron (1996) 0.90

Both augmentation and potentiation occur independently of internal Ca2+ at the frog neuromuscular junction. Neurosci Lett (1989) 0.89

Calcium and depolarization dependence of twin-pulse facilitation of synaptic release at nerve terminals of crayfish and frog muscle. Pflugers Arch (1989) 0.85

Study of the inhibitor of the crayfish neuromuscular junction by presynaptic voltage control. J Neurophysiol (1997) 0.83

Activation and detection of facilitation as studied by presynaptic voltage control at the inhibitor of the crayfish opener muscle. J Neurophysiol (1997) 0.83

Neurotransmitter release: facilitation and three-dimensional diffusion of intracellular calcium. Bull Math Biol (1992) 0.79

Activity-dependent potentiation of synaptic transmission from L30 inhibitory interneurons of aplysia depends on residual presynaptic Ca2+ but not on postsynaptic Ca2+. J Neurophysiol (1997) 0.78

Articles by these authors

(truncated to the top 100)

Comparison between single-dose and divided-dose administration of dactinomycin and doxorubicin for patients with Wilms' tumor: a report from the National Wilms' Tumor Study Group. J Clin Oncol (1998) 3.53

Multiple calcium-dependent processes related to secretion in bovine chromaffin cells. Neuron (1993) 3.52

Kinetics of the secretory response in bovine chromaffin cells following flash photolysis of caged Ca2+. Biophys J (1994) 3.14

Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission. Science (1988) 3.00

Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels. Nat Neurosci (2000) 2.77

Selective induction of LTP and LTD by postsynaptic [Ca2+]i elevation. J Neurophysiol (1999) 2.76

Role of presynaptic calcium ions and channels in synaptic facilitation and depression at the squid giant synapse. J Physiol (1982) 2.73

Aequorin response facilitation and intracellular calcium accumulation in molluscan neurones. J Physiol (1980) 2.58

A comparison of outcomes in men 11 years after heart-valve replacement with a mechanical valve or bioprosthesis. Veterans Affairs Cooperative Study on Valvular Heart Disease. N Engl J Med (1993) 2.50

Changes in the statistics of transmitter release during facilitation. J Physiol (1973) 2.47

Mitochondrial involvement in post-tetanic potentiation of synaptic transmission. Neuron (1997) 2.35

Dusty starburst galaxies in the early Universe as revealed by gravitational lensing. Nature (2013) 2.35

Presynaptic calcium diffusion from various arrays of single channels. Implications for transmitter release and synaptic facilitation. Biophys J (1985) 2.33

Acid-fast bacilli in sputum smears of patients with pulmonary tuberculosis. Prevalence and significance of negative smears pretreatment and positive smears post-treatment. Am Rev Respir Dis (1984) 2.19

Time course of transmitter release calculated from simulations of a calcium diffusion model. Biophys J (1992) 2.16

Increased incidence of herpes zoster in the setting of cytomegalovirus preemptive therapy after kidney transplantation. Transpl Infect Dis (2013) 2.09

Residual Ca2+ and short-term synaptic plasticity. Nature (1994) 1.95

Relationship between transmitter release and presynaptic calcium influx when calcium enters through discrete channels. Proc Natl Acad Sci U S A (1986) 1.86

Fiberoptic endoscopic evaluation of swallowing with sensory testing (FEESST) in healthy controls. Dysphagia (1998) 1.71

Ultrasonographic measurement of induced myopia associated with capsular bag distention syndrome. Ophthalmology (2000) 1.70

Presynaptic calcium diffusion and the time courses of transmitter release and synaptic facilitation at the squid giant synapse. J Neurosci (1983) 1.69

Crayfish escape behavior and central synapses. II. Physiological mechanisms underlying behavioral habituation. J Neurophysiol (1972) 1.66

Mechanisms determining the time course of secretion in neuroendocrine cells. Neuron (1996) 1.62

Characteristics of crayfish neuromuscular facilitation and their calcium dependence. J Physiol (1974) 1.61

Clinical implications of detection of Ureaplasma urealyticum in the amniotic cavity with the polymerase chain reaction. Am J Obstet Gynecol (2000) 1.57

Effect of duration of treatment on treatment outcome and cost of treatment for Wilms' tumor: a report from the National Wilms' Tumor Study Group. J Clin Oncol (1998) 1.56

Anesthesia for intraocular surgery. Surv Ophthalmol (2001) 1.49

Production of the RANTES chemokine in delayed-type hypersensitivity reactions: involvement of macrophages and endothelial cells. J Exp Med (1994) 1.49

Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder. J Am Acad Child Adolesc Psychiatry (2000) 1.48

Calcium in motor nerve terminals associated with posttetanic potentiation. J Neurosci (1989) 1.47

Fractionated total lymphoid irradiation as preparative immunosuppression in high risk renal transplantation: clinical and immunological studies. Ann Surg (1982) 1.44

Generation of multiple electrosprays using microfabricated emitter arrays for improved mass spectrometric sensitivity. Anal Chem (2001) 1.44

Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation. Neuron (1992) 1.42

Crayfish neuromuscular facilitation activated by constant presynaptic action potentials and depolarizing pulses. J Physiol (1974) 1.42

Tetraethylammonium contains an impurity which alkalizes cytoplasm and reduce calcium buffering in neurons. Brain Res (1981) 1.42

Secondary hemorrhage in traumatic hyphema. Am J Ophthalmol (1991) 1.40

Induction of filopodia by direct local elevation of intracellular calcium ion concentration. J Cell Biol (1999) 1.38

A massive, cooling-flow-induced starburst in the core of a luminous cluster of galaxies. Nature (2012) 1.36

Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm. J Biol Chem (2001) 1.34

Glutamine-dependent antiapoptotic interaction of human glutaminyl-tRNA synthetase with apoptosis signal-regulating kinase 1. J Biol Chem (2000) 1.34

Control of cytoplasmic calcium with photolabile tetracarboxylate 2-nitrobenzhydrol chelators. Biophys J (1986) 1.33

Imaging properties of scanning holographic microscopy. J Opt Soc Am A Opt Image Sci Vis (2000) 1.33

A cofactor of tRNA synthetase, p43, is secreted to up-regulate proinflammatory genes. J Biol Chem (2001) 1.32

Evaluation of the AMPLICOR CMV test for direct detection of cytomegalovirus in plasma specimens. J Clin Microbiol (1997) 1.32

Calcium released by photolysis of DM-nitrophen stimulates transmitter release at squid giant synapse. J Physiol (1990) 1.31

Ca2+ cooperativity in neurosecretion measured using photolabile Ca2+ chelators. J Neurophysiol (1994) 1.31

Calcium-induced inactivation of calcium current causes the inter-burst hyperpolarization of Aplysia bursting neurones. J Physiol (1985) 1.29

Postsynaptic levels of [Ca2+]i needed to trigger LTD and LTP. Neuron (1996) 1.25

Neuronal circuit mediating escape responses in crayfish. Science (1971) 1.24

Regulation of macrophage migration inhibitory factor and thiol-specific antioxidant protein PAG by direct interaction. J Biol Chem (2001) 1.24

Photolytic manipulation of Ca2+ and the time course of slow, Ca(2+)-activated K+ current in rat hippocampal neurones. J Physiol (1994) 1.23

Release of LHRH is linearly related to the time integral of presynaptic Ca2+ elevation above a threshold level in bullfrog sympathetic ganglia. Neuron (1993) 1.21

Action potentials must admit calcium to evoke transmitter release. Nature (1991) 1.19

Excitability changes in crayfish motor neurone terminals. J Physiol (1974) 1.18

Modulation of M-current by intracellular Ca2+. Neuron (1991) 1.17

The antiretrovirus drug 3'-azido-3'-deoxythymidine increases the retrovirus mutation rate. J Virol (1997) 1.16

Helical CT during arterial portography and hepatic arteriography for detecting hypervascular hepatocellular carcinoma. AJR Am J Roentgenol (1997) 1.15

Calcium-dependent inward current in Aplysia bursting pace-maker neurones. J Physiol (1985) 1.15

Phosphorylation of Ser-42 and Ser-59 in the N-terminal region of the tyrosine kinase p56lck. Proc Natl Acad Sci U S A (1993) 1.14

Angiomyolipoma of the liver with least amount of fat component: imaging features of CT, MR, and angiography. Abdom Imaging (2002) 1.12

Thyroid nodules: re-evaluation with ultrasound. J Clin Ultrasound (1995) 1.11

Particle-yield modification in jetlike azimuthal dihadron correlations in Pb-Pb collisions at √s(NN)=2.76 TeV. Phys Rev Lett (2012) 1.11

Treatment of children with stages II to IV anaplastic Wilms' tumor: a report from the National Wilms' Tumor Study Group. J Clin Oncol (1994) 1.11

The role of cotranscriptional histone methylations. Cold Spring Harb Symp Quant Biol (2011) 1.11

Tissue ingrowth and bowel adhesion formation in an animal comparative study: polypropylene versus Proceed versus Parietex Composite. Surg Endosc (2007) 1.11

Hypervascular hepatocellular carcinoma: detection with double arterial phase multi-detector row helical CT. Radiology (2001) 1.10

F-actin disruption attenuates agonist-induced [Ca2+], myosin phosphorylation, and force in smooth muscle. Am J Physiol (1997) 1.09

Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation. Neuron (2001) 1.08

Post-tetanic decay of evoked and spontaneous transmitter release and a residual-calcium model of synaptic facilitation at crayfish neuromuscular junctions. J Gen Physiol (1983) 1.08

Transverse momentum distribution and nuclear modification factor of charged particles in p+Pb collisions at sqrt[s(NN)] = 5.02 TeV. Phys Rev Lett (2013) 1.08

Newly secreted adenylate cyclase toxin is responsible for intoxication of target cells by Bordetella pertussis. Mol Microbiol (2004) 1.07

Antibody cross-linking of myelin oligodendrocyte glycoprotein leads to its rapid repartitioning into detergent-insoluble fractions, and altered protein phosphorylation and cell morphology. J Neurosci (2003) 1.07

Roles for mitochondrial and reverse mode Na+/Ca2+ exchange and the plasmalemma Ca2+ ATPase in post-tetanic potentiation at crayfish neuromuscular junctions. J Neurosci (2001) 1.07

Adjustment problems of Korean American elderly. Gerontologist (1985) 1.07

Laryngopharyngeal sensory discrimination testing and the laryngeal adductor reflex. Ann Otol Rhinol Laryngol (1999) 1.06

Presynaptic calcium and serotonin-mediated enhancement of transmitter release at crayfish neuromuscular junction. J Neurosci (1991) 1.06

Prevention of the cortical reaction in fertilized sea urchin eggs by injection of calcium-chelating ligands. Biochim Biophys Acta (1978) 1.06

Lack of correlation between gallbladder opacification in delayed CT and contrast-associated nephropathy. Eur Radiol (1997) 1.05

FEESST: a new bedside endoscopic test of the motor and sensory components of swallowing. Ann Otol Rhinol Laryngol (1998) 1.05

CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons. Int J Cancer (1999) 1.04

Mechanism of transmitter release: voltage hypothesis and calcium hypothesis. Science (1986) 1.04

Mechanism of efavirenz influence on methadone pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther (2012) 1.04

MR imaging of mesenteric hemangioma: a case report. Radiat Med (2000) 1.02

Intracellular calcium release and the mechanisms of parthenogenetic activation of the sea urchin egg. Dev Biol (1978) 1.02

Presynaptic effectors contributing to cAMP-induced synaptic potentiation in Drosophila. J Neurobiol (2006) 1.01

Comparison of autologous and allogeneic bone marrow transplantation for treatment of high-risk refractory acute lymphoblastic leukemia. N Engl J Med (1987) 1.01

Indications for and outcomes of repeat penetrating keratoplasty, 1989-1995. Ophthalmology (2000) 1.00

FADD self-association is required for stable interaction with an activated death receptor. Cell Death Differ (2006) 1.00

Thyroid dysfunction following bone marrow transplantation: long-term follow-up of 80 pediatric patients. Bone Marrow Transplant (1990) 0.99

Production of muons from heavy flavor decays at forward rapidity in pp and Pb-Pb collisions at sqrt[s(NN)]=2.76  TeV. Phys Rev Lett (2012) 0.98

Regulation of synaptic vesicle recycling by calcium and serotonin. Neuron (1998) 0.98

Treatment of newly diagnosed children and adolescents with acute myeloid leukemia: a Childrens Cancer Group study. J Clin Oncol (1994) 0.97

Modification of Ser59 in the unique N-terminal region of tyrosine kinase p56lck regulates specificity of its Src homology 2 domain. Proc Natl Acad Sci U S A (1995) 0.97

Autologous bone marrow transplantation for patients with acute lymphoblastic leukemia in second or subsequent remission: results of bone marrow treated with monoclonal antibodies BA-1, BA-2, and BA-3 plus complement. Blood (1985) 0.97

Sensitivity in detection of hypervascular hepatocellular carcinoma by helical CT with intra-arterial injection of contrast medium, and by helical CT and MR imaging with intravenous injection of contrast medium. Acta Radiol (1998) 0.96

Fulminant leptospirosis in a patient with human immunodeficiency virus infection: case report and review of the literature. Clin Infect Dis (2001) 0.95

The bladder and bladder tumors: imaging with three-dimensional display of helical CT data. AJR Am J Roentgenol (1996) 0.95

Chemotherapeutic DNA-damaging drugs activate interferon regulatory factor-7 by the mitogen-activated protein kinase kinase-4-cJun NH2-terminal kinase pathway. Cancer Res (2000) 0.94

Impact of a galanin antagonist on exogenous galanin and natural patterns of fat ingestion. Brain Res (1992) 0.94

Desensitization protocol in highly HLA-sensitized and ABO-incompatible high titer kidney transplantation. Transplant Proc (2010) 0.93