Transcriptional regulation of adipogenesis.

PubWeight™: 8.52‹?› | Rank: Top 0.1%

🔗 View Article (PMID 10837022)

Published in Genes Dev on June 01, 2000

Authors

E D Rosen1, C J Walkey, P Puigserver, B M Spiegelman

Author Affiliations

1: Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115 USA. edrosen@massmed.org

Articles citing this

(truncated to the top 100)

CCAAT/enhancer-binding proteins: structure, function and regulation. Biochem J (2002) 6.83

C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev (2002) 6.46

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev (2003) 5.91

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. J Clin Invest (2004) 5.29

Regulation of osteoblastogenesis and bone mass by Wnt10b. Proc Natl Acad Sci U S A (2005) 4.48

Mammalian Krüppel-like factors in health and diseases. Physiol Rev (2010) 4.09

Mitotic clonal expansion: a synchronous process required for adipogenesis. Proc Natl Acad Sci U S A (2002) 3.67

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice. Cell Metab (2008) 3.45

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation. Proc Natl Acad Sci U S A (2004) 3.45

MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation. Stem Cells (2010) 3.16

Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell (2013) 3.00

Elevated sensitivity to diet-induced obesity and insulin resistance in mice lacking 4E-BP1 and 4E-BP2. J Clin Invest (2007) 2.86

Cidea is associated with lipid droplets and insulin sensitivity in humans. Proc Natl Acad Sci U S A (2008) 2.71

CCAAT/enhancer-binding protein beta is required for mitotic clonal expansion during adipogenesis. Proc Natl Acad Sci U S A (2003) 2.65

C elegans: a model for exploring the genetics of fat storage. Dev Cell (2003) 2.56

RIP140-targeted repression of gene expression in adipocytes. Mol Cell Biol (2005) 2.52

Peroxisome proliferator-activated receptor gamma is required in mature white and brown adipocytes for their survival in the mouse. Proc Natl Acad Sci U S A (2004) 2.46

Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol (2002) 2.44

What can we learn from rodents about prolactin in humans? Endocr Rev (2007) 2.38

Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis. Cell (2007) 2.35

A role of miR-27 in the regulation of adipogenesis. FEBS J (2009) 2.27

Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis. Biochem J (2003) 2.26

Regulatory circuits controlling white versus brown adipocyte differentiation. Biochem J (2006) 2.23

Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity. Proc Natl Acad Sci U S A (2004) 2.21

Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metab (2011) 2.21

Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots. Mol Cell Biol (2005) 2.18

Multiple organ system defects and transcriptional dysregulation in the Nipbl(+/-) mouse, a model of Cornelia de Lange Syndrome. PLoS Genet (2009) 2.14

Differential roles of insulin receptor substrates in brown adipocyte differentiation. Mol Cell Biol (2004) 2.14

Loss of wnt/β-catenin signaling causes cell fate shift of preosteoblasts from osteoblasts to adipocytes. J Bone Miner Res (2012) 2.01

Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation. Mol Cell Biol (2005) 1.92

Long noncoding RNAs regulate adipogenesis. Proc Natl Acad Sci U S A (2013) 1.90

NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis. Mol Cell Biol (2007) 1.86

Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade. Mol Cell Biol (2006) 1.86

Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J Biol Chem (2009) 1.86

Differentiation of embryonic mesenchymal cells to odontoblast-like cells by overexpression of dentin matrix protein 1. Proc Natl Acad Sci U S A (2001) 1.85

Wnt/beta-catenin signaling in adipogenesis and metabolism. Curr Opin Cell Biol (2007) 1.84

Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades. Mol Cell Biol (2005) 1.80

Characterization of differential properties of rabbit tendon stem cells and tenocytes. BMC Musculoskelet Disord (2010) 1.80

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci U S A (2008) 1.80

Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors. Mol Cell Biol (2003) 1.79

Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2004) 1.74

Phosphorylation of C/EBPbeta at a consensus extracellular signal-regulated kinase/glycogen synthase kinase 3 site is required for the induction of adiponectin gene expression during the differentiation of mouse fibroblasts into adipocytes. Mol Cell Biol (2004) 1.73

Hic-5 regulates an epithelial program mediated by PPARgamma. Genes Dev (2005) 1.73

Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice. Autophagy (2009) 1.72

Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PLoS One (2010) 1.70

Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes. Proc Natl Acad Sci U S A (2001) 1.69

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis. Proc Natl Acad Sci U S A (2008) 1.67

Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation. Mol Cell Biol (2002) 1.64

Cyclin D3 promotes adipogenesis through activation of peroxisome proliferator-activated receptor gamma. Mol Cell Biol (2005) 1.63

Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation. Mol Cell Biol (2001) 1.62

Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes. J Cell Biol (2002) 1.58

Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (2003) 1.57

Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol Cell Biol (2004) 1.55

Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation. Scientifica (Cairo) (2013) 1.51

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes. J Lipid Res (2011) 1.50

Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases. Mol Cell Biol (2002) 1.50

Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A (2006) 1.49

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts. Mol Biol Cell (2005) 1.47

Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. Mol Cell Biol (2001) 1.46

Regulation of Adipogenesis and Key Adipogenic Gene Expression by 1, 25-Dihydroxyvitamin D in 3T3-L1 Cells. PLoS One (2015) 1.46

C/EBPdelta regulates cell cycle and self-renewal of human limbal stem cells. J Cell Biol (2007) 1.40

Myocardial lipid accumulation in patients with pressure-overloaded heart and metabolic syndrome. J Lipid Res (2009) 1.38

Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37

Adipocyte, adipose tissue, and infectious disease. Infect Immun (2006) 1.36

Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by rosiglitazone suppresses components of the insulin-like growth factor regulatory system in vitro and in vivo. Endocrinology (2006) 1.36

LRP1 controls intracellular cholesterol storage and fatty acid synthesis through modulation of Wnt signaling. J Biol Chem (2008) 1.36

The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis. Mol Cell Biol (2005) 1.35

Ectodomain shedding of preadipocyte factor 1 (Pref-1) by tumor necrosis factor alpha converting enzyme (TACE) and inhibition of adipocyte differentiation. Mol Cell Biol (2006) 1.35

PPARs in the Control of Uncoupling Proteins Gene Expression. PPAR Res (2007) 1.34

RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27. Acta Physiol (Oxf) (2008) 1.33

Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation. Proc Natl Acad Sci U S A (2009) 1.33

Unraveling the mechanism of action of thiazolidinediones. J Clin Invest (2000) 1.33

The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Endocrinology (2009) 1.32

Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha. Mol Cell Biol (2005) 1.31

Adipose is a conserved dosage-sensitive antiobesity gene. Cell Metab (2007) 1.31

C/EBP transcription factors regulate SREBP1c gene expression during adipogenesis. Biochem J (2009) 1.28

Peroxisome proliferator-activated receptor targets for the treatment of metabolic diseases. Mediators Inflamm (2013) 1.27

'Metabolically healthy obesity': origins and implications. Mol Aspects Med (2012) 1.27

Brd2 disruption in mice causes severe obesity without Type 2 diabetes. Biochem J (2009) 1.26

Rapid cellular turnover in adipose tissue. PLoS One (2011) 1.26

Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol (2008) 1.26

Effect of a C/EBP gene replacement on mitochondrial biogenesis in fat cells. Genes Dev (2004) 1.26

Emergence during development of the white-adipocyte cell phenotype is independent of the brown-adipocyte cell phenotype. Biochem J (2001) 1.24

Overexpression of glucose-6-phosphate dehydrogenase is associated with lipid dysregulation and insulin resistance in obesity. Mol Cell Biol (2005) 1.24

Adipose tissue: friend or foe? Nat Rev Cardiol (2012) 1.24

Dietary polyphenols and obesity. Nutrients (2010) 1.23

Programmed upregulation of adipogenic transcription factors in intrauterine growth-restricted offspring. Reprod Sci (2008) 1.23

Characterization of microRNA expression in bovine adipose tissues: a potential regulatory mechanism of subcutaneous adipose tissue development. BMC Mol Biol (2010) 1.23

The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro. J Biol Chem (2005) 1.23

UCP1: its involvement and utility in obesity. Int J Obes (Lond) (2008) 1.22

Decreased expression of adipogenic genes in obese subjects with type 2 diabetes. Obesity (Silver Spring) (2006) 1.21

Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells. Mol Cell Biol (2008) 1.20

The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers. Mol Cell Biol (2002) 1.19

Involvement of matrix metalloproteinases in the adipose conversion of 3T3-L1 preadipocytes. Biochem J (2002) 1.18

Misexpression of CCAAT/enhancer binding protein beta causes osteopenia. J Endocrinol (2009) 1.14

Krüppel-like family of transcription factors: an emerging new frontier in fat biology. Int J Biol Sci (2009) 1.12

Effects of age and dysfunction on human meibomian glands. Arch Ophthalmol (2011) 1.11

Retinol saturase promotes adipogenesis and is downregulated in obesity. Proc Natl Acad Sci U S A (2009) 1.11

Krüppel-like factor KLF9 regulates PPARγ transactivation at the middle stage of adipogenesis. Cell Death Differ (2010) 1.11

The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure. PLoS One (2010) 1.10

Articles by these authors

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science (1993) 25.54

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell (1999) 19.48

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell (1998) 18.32

Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell (1994) 17.58

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature (2001) 11.72

15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell (1995) 11.72

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. Genes Dev (1994) 10.44

PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro. Mol Cell (1999) 9.74

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest (1995) 9.59

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science (1996) 8.57

CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature (2001) 8.44

Towards a molecular understanding of adaptive thermogenesis. Nature (2000) 7.04

AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem (1996) 6.93

ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. Genes Dev (1996) 6.54

Molecular regulation of adipogenesis. Annu Rev Cell Dev Biol (2000) 6.40

PPARgamma : a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem (2001) 5.85

ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol Cell Biol (1993) 5.34

Differentiation and reversal of malignant changes in colon cancer through PPARgamma. Nat Med (1998) 5.16

Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity. Mol Cell (1999) 4.89

Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1. J Clin Invest (1998) 4.85

Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes (1994) 4.66

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science (1996) 4.61

Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1. Mol Cell (2001) 4.58

Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma. Science (1996) 4.50

Common DNA binding site for Fos protein complexes and transcription factor AP-1. Cell (1988) 4.38

Activation of PPARgamma coactivator-1 through transcription factor docking. Science (1999) 4.33

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nat Med (2001) 4.19

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development. J Biol Chem (1983) 4.14

Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A (1994) 4.08

Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1. Proc Natl Acad Sci U S A (2001) 3.96

Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos. Cell (1987) 3.89

PAX8-PPARgamma1 fusion oncogene in human thyroid carcinoma [corrected]. Science (2000) 3.87

Terminal differentiation of human breast cancer through PPAR gamma. Mol Cell (1998) 3.71

ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand. Proc Natl Acad Sci U S A (1998) 3.61

Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol Cell Biol (2000) 3.60

Transdifferentiation of myoblasts by the adipogenic transcription factors PPAR gamma and C/EBP alpha. Proc Natl Acad Sci U S A (1995) 3.56

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor. Proc Natl Acad Sci U S A (1997) 3.22

A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev (1993) 3.21

Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes. Cell (1983) 3.19

Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J Clin Invest (1994) 3.16

PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol Cell Biol (1995) 3.14

Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol Cell Biol (1995) 3.10

Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol Cell (2000) 3.00

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med (2001) 2.81

Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell (1992) 2.78

Loss-of-function mutations in PPAR gamma associated with human colon cancer. Mol Cell (1999) 2.71

Adipocyte P2 gene: developmental expression and homology of 5'-flanking sequences among fat cell-specific genes. Proc Natl Acad Sci U S A (1986) 2.70

Targeted expression of a toxin gene to adipose tissue: transgenic mice resistant to obesity. Genes Dev (1993) 2.68

A fat-specific enhancer is the primary determinant of gene expression for adipocyte P2 in vivo. Proc Natl Acad Sci U S A (1990) 2.66

Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha. Nucleic Acids Res (1994) 2.58

Differential activation of adipogenesis by multiple PPAR isoforms. Genes Dev (1996) 2.58

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma. Proc Natl Acad Sci U S A (1999) 2.45

c-fos is required for malignant progression of skin tumors. Cell (1995) 2.39

Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene. J Biol Chem (1997) 2.36

A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation. Mol Cell Biol (1989) 2.33

Control of specific protein biosynthesis during the adipose conversion of 3T3 cells. J Biol Chem (1980) 2.33

Decreases in tubulin and actin gene expression prior to morphological differentiation of 3T3 adipocytes. Cell (1982) 2.30

PPARgamma induces cell cycle withdrawal: inhibition of E2F/DP DNA-binding activity via down-regulation of PP2A. Genes Dev (1997) 2.29

Multiple sites for the initiation of microtubule assembly in mammalian cells. Cell (1979) 2.25

A synthetic antagonist for the peroxisome proliferator-activated receptor gamma inhibits adipocyte differentiation. J Biol Chem (2000) 2.24

Effects of ligand activation of peroxisome proliferator-activated receptor gamma in human prostate cancer. Proc Natl Acad Sci U S A (2000) 2.23

Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor gamma. Curr Opin Genet Dev (1995) 2.16

Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways. J Biol Chem (1992) 2.12

Degradation of the peroxisome proliferator-activated receptor gamma is linked to ligand-dependent activation. J Biol Chem (2000) 2.10

Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. Endocrinology (1994) 2.10

Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1: implications for adipocyte differentiation and metabolism. Mol Cell Biol (1999) 2.05

Severely impaired adipsin expression in genetic and acquired obesity. Science (1987) 2.03

Developmentally regulated mRNAs in 3T3-adipocytes: analysis of transcriptional control. J Cell Biol (1985) 1.91

Adipsin and an endogenous pathway of complement from adipose cells. J Biol Chem (1992) 1.88

Adipsin and complement factor D activity: an immune-related defect in obesity. Science (1989) 1.87

Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem (1996) 1.85

Aggregation of microtubule initiation sites preceding neurite outgrowth in mouse neuroblastoma cells. Cell (1979) 1.83

Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science (1987) 1.77

Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha. Mol Endocrinol (1996) 1.75

Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science (1989) 1.75

Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation. Proc Natl Acad Sci U S A (1986) 1.75

Identification of a potent adipocyte-specific enhancer: involvement of an NF-1-like factor. Genes Dev (1991) 1.74

Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissue. J Biol Chem (1992) 1.74

Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1. J Biol Chem (2000) 1.70

Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression. Mol Cell Biol (1992) 1.70

Fatty acid regulation of gene expression. Transcriptional and post-transcriptional mechanisms. J Biol Chem (1992) 1.62

Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J (1994) 1.61

Differentiation-dependent stimulation of neovascularization and endothelial cell chemotaxis by 3T3 adipocytes. Proc Natl Acad Sci U S A (1982) 1.58

Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene. Proc Natl Acad Sci U S A (1992) 1.57

A developmentally regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue. Proc Natl Acad Sci U S A (1985) 1.55

Phosphatidylethanolamine N-methyltransferase from liver. Biochim Biophys Acta (1997) 1.55

Identification of a fat cell enhancer: analysis of requirements for adipose tissue-specific gene expression. J Cell Biochem (1992) 1.54

Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2. J Biol Chem (1999) 1.47

Turnover of tubulin and the N site GTP in Chinese hamster ovary cells. Cell (1977) 1.45

The unique acyl chain specificity of biliary phosphatidylcholines in mice is independent of their biosynthetic origin in the liver. Hepatology (1999) 1.44

Functional antagonism between CCAAT/Enhancer binding protein-alpha and peroxisome proliferator-activated receptor-gamma on the leptin promoter. J Biol Chem (1997) 1.42

Transgenic mice overexpressing the beta 1-adrenergic receptor in adipose tissue are resistant to obesity. Mol Endocrinol (1997) 1.37

Potent stimulation of vascular endothelial cell growth by differentiated 3T3 adipocytes. Proc Natl Acad Sci U S A (1980) 1.34

Adipsin, the adipocyte serine protease: gene structure and control of expression by tumor necrosis factor. Nucleic Acids Res (1986) 1.34

Posttranscriptional control of adipocyte differentiation through activation of phosphoinositide 3-kinase. J Biol Chem (1998) 1.33