Published in Am J Pathol on June 01, 2000
Disseminated and sustained HIV infection in CD34+ cord blood cell-transplanted Rag2-/-gamma c-/- mice. Proc Natl Acad Sci U S A (2006) 3.07
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient. PLoS Pathog (2013) 2.44
Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy. Proc Natl Acad Sci U S A (2005) 1.54
The level of virus-specific T-cell and macrophage recruitment in porcine reproductive and respiratory syndrome virus infection in pigs is independent of virus load. J Virol (2004) 1.44
The distribution of HIV DNA and RNA in cell subsets differs in gut and blood of HIV-positive patients on ART: implications for viral persistence. J Infect Dis (2013) 1.39
Macrophage signaling in HIV-1 infection. Retrovirology (2010) 1.35
Detection of HIV gp120 in plasma during early HIV infection is associated with increased proinflammatory and immunoregulatory cytokines. AIDS Res Hum Retroviruses (2010) 1.02
T-Cell Signaling in HIV-1 Infection. Open Virol J (2013) 0.83
Both R5 and X4 human immunodeficiency virus type 1 variants persist during prolonged therapy with five antiretroviral drugs. J Virol (2002) 0.80
Exogenous HIV-1 Nef upsets the IFN-γ-induced impairment of human intestinal epithelial integrity. PLoS One (2011) 0.77
Vpx mediated degradation of SAMHD1 has only a very limited effect on lentiviral transduction rate in ex vivo cultured HSPCs. Stem Cell Res (2015) 0.77
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature (1993) 15.54
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy. N Engl J Med (1999) 7.07
Kinetics of response in lymphoid tissues to antiretroviral therapy of HIV-1 infection. Science (1997) 5.55
Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med (1999) 5.18
Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy. JAMA (1999) 4.98
Quantitative image analysis of HIV-1 infection in lymphoid tissue. Science (1996) 4.72
Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. Annu Rev Immunol (1999) 4.66
Lymphoid organs function as major reservoirs for human immunodeficiency virus. Proc Natl Acad Sci U S A (1991) 4.23
Follicular dendritic cells and human immunodeficiency virus infectivity. Nature (1995) 3.22
Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA. J Infect Dis (1991) 3.16
HTLV-III/LAV viral antigens in lymph nodes of homosexual men with persistent generalized lymphadenopathy and AIDS. Am J Pathol (1986) 2.77
Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy. J Virol (1999) 2.42
Kinetics of CD4+ T cell repopulation of lymphoid tissues after treatment of HIV-1 infection. Proc Natl Acad Sci U S A (1998) 2.39
Follicular dendritic cells are a major reservoir for human immunodeficiency virus type 1 in lymphoid tissues facilitating infection of CD4+ T-helper cells. Am J Pathol (1992) 2.37
Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure. Proc Natl Acad Sci U S A (1997) 2.11
Protease inhibitor-containing regimens compared with nucleoside analogues alone in the suppression of persistent HIV-1 replication in lymphoid tissue. AIDS (1999) 2.00
HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy. Am J Pathol (1986) 1.88
Human immunodeficiency virus replication and genotypic resistance in blood and lymph nodes after a year of potent antiretroviral therapy. J Virol (1998) 1.75
Early reduction of immune activation in lymphoid tissue following highly active HIV therapy. AIDS (1998) 1.69
Cellular localization of an HIV-1 antigen in subacute AIDS encephalitis using an improved double-labeling immunohistochemical method. Am J Pathol (1990) 1.67
Detection of low HIV-1 RNA levels in plasma. J Acquir Immune Defic Syndr Hum Retrovirol (1997) 1.65
Highly sensitive methods for quantitation of human immunodeficiency virus type 1 RNA from plasma, cells, and tissues. J Clin Microbiol (1999) 1.53
Binding of human immunodeficiency virus type-1 to follicular dendritic cells in vitro is complement dependent. J Immunol (1993) 1.45
HIV-1 infection and virus production in follicular dendritic cells in lymph nodes. A case report, with analysis of isolated follicular dendritic cells. Am J Pathol (1990) 1.24
Active replication of HIV-1 at the lymphoepithelial surface of the tonsil. Am J Pathol (1997) 1.22
Reversibility of the pathological changes in the follicular dendritic cell network with treatment of HIV-1 infection. Proc Natl Acad Sci U S A (1999) 1.16
Expression of HIV in lymph node cells of LAS patients. Immunohistology, in situ hybridization, and identification of target cells. Am J Pathol (1988) 1.16
Cell-associated HIV-1 RNA in blood as indicator of virus load in lymph nodes. The Swiss HIV Cohort Study. J Infect Dis (1999) 1.14
Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study. AIDS (1998) 1.12
Follicular dendritic cells retain HIV-1 particles on their plasma membrane, but are not productively infected in asymptomatic patients with follicular hyperplasia. J Immunol (1994) 1.09
Methodologies for specific intron and exon RNA localization in cultured cells by haptenized and fluorochromized probes. J Cell Sci (1993) 1.05
HIV is trapped and masked in the cytoplasm of lymph node follicular dendritic cells. Am J Pathol (1997) 1.03
Reduced CD4 cell counts in blood do not reflect CD4 cell depletion in tonsillar tissue in asymptomatic HIV-1 infection. AIDS (1996) 1.02
Human follicular dendritic cells remain uninfected and capture human immunodeficiency virus type 1 through CD54-CD11a interaction. J Virol (1999) 1.01
Subcellular localization of low-abundance human immunodeficiency virus nucleic acid sequences visualized by fluorescence in situ hybridization. Proc Natl Acad Sci U S A (1990) 0.97
In situ hybridization of human immunodeficiency virus (HTLV-III) in cryostat sections of lymph nodes of lymphadenopathy syndrome patients. J Med Virol (1987) 0.92
Effects of early antiretroviral treatment on HIV-1 RNA in blood and lymphoid tissue: a randomized trial of double versus triple therapy. Swiss HIV Cohort Study. J Acquir Immune Defic Syndr (2000) 0.90
Lymphoid changes of the nasopharyngeal and palatine tonsils that are indicative of human immunodeficiency virus infection. A clinicopathologic study of 12 cases. Am J Surg Pathol (1996) 0.87
Studies on lymphoid tissue from HIV-infected individuals: implications for the design of therapeutic strategies. Springer Semin Immunopathol (1997) 0.86
Confocal microscopy assessment of lymphoid tissues with follicular hyperplasia from patients infected with human immunodeficiency virus type 1. Arch Pathol Lab Med (1998) 0.82
Detection of HIV-1 DNA in cells and tissue by fluorescent in situ 5'-nuclease assay (FISNA). Nucleic Acids Res (1996) 0.80
Evaluation of cell-free and cell-associated peripheral blood human immunodeficiency virus type 1 RNA response to antiretroviral therapy. J Infect Dis (1999) 0.78
In situ hybridization of HIV-1 RNA in retinal vascular wall. Am J Pathol (1993) 0.78
Single copies of HIV proviral DNA detected by fluorescent in situ hybridization. Biotechniques (1990) 0.78
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell (1997) 15.96
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science (1997) 15.12
A method to identify protein sequences that fold into a known three-dimensional structure. Science (1991) 14.08
Profile analysis. Methods Enzymol (1990) 9.40
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature (1992) 9.01
VERIFY3D: assessment of protein models with three-dimensional profiles. Methods Enzymol (1997) 6.71
Potent antiretroviral treatment of HIV-infection results in suppression of the seminal shedding of HIV. The Swiss HIV Cohort Study. AIDS (2000) 4.91
Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet (1999) 4.83
Differentiation of phylogenetically related slowly growing mycobacteria based on 16S-23S rRNA gene internal transcribed spacer sequences. J Clin Microbiol (1998) 4.82
Vitellogenin in Xenopus laevis is encoded in a small family of genes. Cell (1979) 4.44
Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature (1996) 4.25
The adolescent outcome of hyperactive children diagnosed by research criteria: I. An 8-year prospective follow-up study. J Am Acad Child Adolesc Psychiatry (1990) 4.02
Diagnostic performance of amplified Mycobacterium tuberculosis direct test with cerebrospinal fluid, other nonrespiratory, and respiratory specimens. J Clin Microbiol (1996) 3.85
Direct detection of Mycobacterium tuberculosis complex in respiratory specimens by a target-amplified test system. J Clin Microbiol (1994) 3.81
Prevalence and predictive value of intermittent viremia with combination hiv therapy. JAMA (2001) 3.73
Novel diagnostic algorithm for identification of mycobacteria using genus-specific amplification of the 16S-23S rRNA gene spacer and restriction endonucleases. J Clin Microbiol (2000) 3.64
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell (1998) 3.59
Localization of a short-term memory in Drosophila. Science (2000) 3.58
AIDS-related opportunistic illnesses occurring after initiation of potent antiretroviral therapy: the Swiss HIV Cohort Study. JAMA (1999) 3.34
A vector for expressing foreign genes in the brains and hearts of transgenic mice. Genet Anal (1996) 3.18
A European evidence-based guideline for the prevention of type 2 diabetes. Horm Metab Res (2010) 3.15
Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence. Proc Natl Acad Sci U S A (2003) 2.95
Antibodies to HTLV-III in Swiss patients with AIDS and pre-AIDS and in groups at risk for AIDS. N Engl J Med (1985) 2.95
HIV viral load response to antiretroviral therapy according to the baseline CD4 cell count and viral load. JAMA (2001) 2.95
The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing. J Biol Chem (1997) 2.85
Organ distribution of Schmallenberg virus RNA in malformed newborns. Vet Microbiol (2012) 2.83
Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5. Circ Res (2000) 2.82
Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides. J Mol Biol (2000) 2.73
Determination of language dominance using functional MRI: a comparison with the Wada test. Neurology (1996) 2.71
Thrombolysis in stroke patients aged 80 years and older: Swiss survey of IV thrombolysis. Neurology (2005) 2.69
Comparison of high-pressure liquid chromatography and bioassay for determination of ciprofloxacin in serum and urine. Antimicrob Agents Chemother (1985) 2.55
Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals. Clin Pharmacol Ther (2007) 2.48
Comparative multiple-dose pharmacokinetics of cefotaxime, moxalactam, and ceftazidime. Antimicrob Agents Chemother (1981) 2.48
Primary pulmonary hypertension in HIV infection. Chest (1991) 2.40
Vitellogenesis and the vitellogenin gene family. Science (1981) 2.39
The use of the Framingham equation to predict myocardial infarctions in HIV-infected patients: comparison with observed events in the D:A:D Study. HIV Med (2006) 2.38
The Swiss HIV Cohort Study: rationale, organization and selected baseline characteristics. Soz Praventivmed (1994) 2.38
Molecular characterization of Cryptosporidium isolates obtained from human immunodeficiency virus-infected individuals living in Switzerland, Kenya, and the United States. J Clin Microbiol (2000) 2.32
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses. Eur J Biochem (2001) 2.30
Human pharmacology of cefotaxime (HR 756), a new cephalosporin. Antimicrob Agents Chemother (1979) 2.29
Effect of standard breakfast on drug absorption and multiple-dose pharmacokinetics of ciprofloxacin. Antimicrob Agents Chemother (1985) 2.25
Hyperlactatemia and antiretroviral therapy: the Swiss HIV Cohort Study. Clin Infect Dis (2001) 2.24
Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature (1996) 2.24
Laparoscopic assisted live donor nephrectomy--a comparison with the open approach. Transplantation (1997) 2.23
Somatic hypermutation in normal and transformed human B cells. Immunol Rev (1998) 2.22
Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice. Genes Dev (1997) 2.21
Clinical evaluation of a Mycobacterium tuberculosis PCR assay. J Clin Microbiol (1995) 2.19
High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene. Mol Med (1994) 2.18
Discontinuation of primary prophylaxis against Pneumocystis carinii pneumonia in HIV-1-infected adults treated with combination antiretroviral therapy. Swiss HIV Cohort Study. N Engl J Med (1999) 2.17
Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice. Neuron (2000) 2.13
The role of clinical suspicion in evaluating a new diagnostic test for active tuberculosis: results of a multicenter prospective trial. JAMA (2000) 2.12
Antioxidant status in patients on chronic hemodialysis therapy: impact of parenteral selenium supplementation. Wien Klin Wochenschr (1997) 2.12
Reduction of HIV-1 in blood and lymph nodes following potent antiretroviral therapy and the virologic correlates of treatment failure. Proc Natl Acad Sci U S A (1997) 2.11
A controlled study of inhaled pentamidine for primary prevention of Pneumocystis carinii pneumonia. N Engl J Med (1991) 2.10
Cerebral microsporidiosis due to Encephalitozoon cuniculi in a patient with human immunodeficiency virus infection. N Engl J Med (1997) 2.05
Delayed diagnosis of HIV infection and late initiation of antiretroviral therapy in the Swiss HIV Cohort Study. HIV Med (2008) 2.03
Fibre-years, pulmonary asbestos burden and asbestosis. Int J Hyg Environ Health (2002) 2.03
No propagation of prions in mice devoid of PrP. Cell (1994) 2.02
Extended-spectrum β-lactamase-producing Gram-negative pathogens in community-acquired urinary tract infections: an increasing challenge for antimicrobial therapy. Infection (2011) 2.00
Take action to prevent diabetes--the IMAGE toolkit for the prevention of type 2 diabetes in Europe. Horm Metab Res (2010) 1.99
Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression. J Virol (2007) 1.98
Cardio- and cerebrovascular events in HIV-infected persons. AIDS (2004) 1.98
Clinical and epidemiologic features of infection with Mycobacterium genavense. Swiss HIV Cohort Study. Arch Intern Med (1995) 1.95
Cervical cancer screening among Cambodian-American women. Cancer Epidemiol Biomarkers Prev (1999) 1.95
Antioxidant status in patients with acute respiratory distress syndrome. Intensive Care Med (1999) 1.91
Epidemic serogroup B meningococcal disease in Oregon: the evolving epidemiology of the ET-5 strain. JAMA (1999) 1.88
Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis. Cell (1980) 1.84
Co-infection with human immunodeficiency virus-type 1 (HIV-1) and cytomegalovirus in two intravenous drug users. Ann Intern Med (1989) 1.82
Plasma protein S deficiency in familial thrombotic disease. Blood (1984) 1.82
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proc Natl Acad Sci U S A (1999) 1.81
Cytokine production by mature and immature CD4-CD8- T cells. Alpha beta-T cell receptor+ CD4-CD8- T cells produce IL-4. J Immunol (1992) 1.80
Isolation and characterisation of the Xenopus laevis albumin genes: loss of 74K albumin gene sequences by library amplification. Nucleic Acids Res (1982) 1.80
Progressive diffuse leukoencephalopathy in patients with acquired immune deficiency syndrome (AIDS). Acta Neuropathol (1985) 1.76
Merkel cell carcinoma: review of 22 cases with surgical, pathologic, and therapeutic considerations. Cancer (2000) 1.76
The Cpx proteins of Escherichia coli K12. Immunologic detection of the chromosomal cpxA gene product. J Biol Chem (1986) 1.75
Cytoskeletal polymer networks: the molecular structure of cross-linkers determines macroscopic properties. Proc Natl Acad Sci U S A (2006) 1.73
High prevalence of Enterocytozoon bieneusi in swine with four genotypes that differ from those identified in humans. Parasitology (1999) 1.70
Extended hepatic resection: a 6-year retrospective study of risk factors for perioperative mortality. J Am Coll Surg (2001) 1.69
Frequent chronic hepatitis B virus infection in HIV-infected patients positive for antibody to hepatitis B core antigen only. Swiss HIV Cohort Study. Eur J Clin Microbiol Infect Dis (1998) 1.69
Prevention of congenital malformations in infants of insulin-dependent diabetic mothers. Diabetes Care (1983) 1.69
Genetic composition of human immunodeficiency virus type 1 in cerebrospinal fluid and blood without treatment and during failing antiretroviral therapy. J Virol (2005) 1.68
Pathologic features and immunofluorescent antibody demonstration of ocular microsporidiosis (Encephalitozoon hellem) in seven patients with acquired immunodeficiency syndrome. Am J Ophthalmol (1993) 1.64
Genetic isolation of fragmented populations is exacerbated by drift and selection. J Evol Biol (2007) 1.64
Quantitation of vitellogenin messenger RNA in the liver of male Xenopus toads during primary and secondary stimulation by estrogen. Cell (1977) 1.64
Production of infectious duck hepatitis B virus in a human hepatoma cell line. J Virol (1988) 1.62
Evidence for effects of interleukin 4 (B cell stimulatory factor 1) on macrophages: enhancement of antigen presenting ability of bone marrow-derived macrophages. J Immunol (1987) 1.62
Enteric viruses and diarrhea in HIV-infected patients. Enteric Opportunistic Infections Working Group. N Engl J Med (1993) 1.60
Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proc Natl Acad Sci U S A (1996) 1.60
Flask-shaped mycoplasmas: properties and pathogenicity for man and animals. Isr J Med Sci (1984) 1.58
The prevalence of poor anticoagulant response to activated protein C (APC resistance) among patients suffering from stroke or venous thrombosis and among healthy subjects. Blood Coagul Fibrinolysis (1994) 1.57
The adolescent outcome of hyperactive children diagnosed by research criteria--III. Mother-child interactions, family conflicts and maternal psychopathology. J Child Psychol Psychiatry (1991) 1.54