Published in Structure on June 15, 2000
Lipopolysaccharide endotoxins. Annu Rev Biochem (2001) 18.88
Molecular basis of bacterial outer membrane permeability revisited. Microbiol Mol Biol Rev (2003) 13.49
Lipid A modification systems in gram-negative bacteria. Annu Rev Biochem (2007) 8.60
Inflammatory caspases are innate immune receptors for intracellular LPS. Nature (2014) 4.88
Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site. EMBO J (2001) 2.24
A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin. EMBO J (2004) 1.60
Diversity and versatility of lipid-protein interactions revealed by molecular genetic approaches. Biochim Biophys Acta (2004) 1.38
Structural biology of membrane-intrinsic beta-barrel enzymes: sentinels of the bacterial outer membrane. Biochim Biophys Acta (2007) 1.22
High resolution crystallographic studies of alpha-hemolysin-phospholipid complexes define heptamer-lipid head group interactions: implication for understanding protein-lipid interactions. Protein Sci (2004) 1.15
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. Proc Natl Acad Sci U S A (2010) 1.14
Lipid-binding surfaces of membrane proteins: evidence from evolutionary and structural analysis. Biochim Biophys Acta (2010) 1.13
Lipid-protein interactions of integral membrane proteins: a comparative simulation study. Biophys J (2004) 1.12
Outer membrane protein X (Ail) contributes to Yersinia pestis virulence in pneumonic plague and its activity is dependent on the lipopolysaccharide core length. Infect Immun (2010) 1.11
Microbe-host interactions: structure and role of Gram-negative bacterial porins. Curr Protein Pept Sci (2012) 1.08
Design, synthesis, and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions. Anal Biochem (2010) 1.06
Evidence of a bactericidal permeability increasing protein in an invertebrate, the Crassostrea gigas Cg-BPI. Proc Natl Acad Sci U S A (2007) 1.02
Immunity to intracellular Salmonella depends on surface-associated antigens. PLoS Pathog (2012) 1.02
Colicin N binds to the periphery of its receptor and translocator, outer membrane protein F. Structure (2008) 1.01
Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria. Bioconjug Chem (2014) 0.99
OmpT: molecular dynamics simulations of an outer membrane enzyme. Biophys J (2004) 0.99
C1 inhibitor: biologic activities that are independent of protease inhibition. Immunobiology (2006) 0.98
Interactions of lipopolysaccharide and polymyxin studied by NMR spectroscopy. J Biol Chem (2009) 0.97
Effects of impurities on membrane-protein crystallization in different systems. Acta Crystallogr D Biol Crystallogr (2009) 0.97
LptE binds to and alters the physical state of LPS to catalyze its assembly at the cell surface. Proc Natl Acad Sci U S A (2014) 0.96
LBP/BPI proteins and their relatives: conservation over evolution and roles in mutualism. Biochem Soc Trans (2011) 0.96
Structural basis for the interaction of lipopolysaccharide with outer membrane protein H (OprH) from Pseudomonas aeruginosa. J Biol Chem (2011) 0.96
Genome-wide screens: novel mechanisms in colicin import and cytotoxicity. Mol Microbiol (2009) 0.95
Designed beta-boomerang antiendotoxic and antimicrobial peptides: structures and activities in lipopolysaccharide. J Biol Chem (2009) 0.94
Fibrinolytic and coagulative activities of Yersinia pestis. Front Cell Infect Microbiol (2013) 0.93
Topomimetics of amphipathic beta-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins. J Med Chem (2006) 0.90
FhuA (TonA), the career of a protein. J Bacteriol (2009) 0.90
Temperature-induced changes in the lipopolysaccharide of Yersinia pestis affect plasminogen activation by the pla surface protease. Infect Immun (2010) 0.89
Functional analysis of the glycero-manno-heptose 7-phosphate kinase domain from the bifunctional HldE protein, which is involved in ADP-L-glycero-D-manno-heptose biosynthesis. J Bacteriol (2005) 0.89
Molecular basis for the increased polymyxin susceptibility of Klebsiella pneumoniae strains with under-acylated lipid A. Innate Immun (2012) 0.89
Significant accumulation of polymyxin in single renal tubular cells: a medicinal chemistry and triple correlative microscopy approach. Anal Chem (2015) 0.86
Structure refinement of the OpcA adhesin using molecular dynamics. Biophys J (2007) 0.86
Modulation of an outer membrane protease contributes to the virulence defect of Shigella flexneri strains carrying a mutation in the virK locus. Infect Immun (2005) 0.86
Kukoamine B, a novel dual inhibitor of LPS and CpG DNA, is a potential candidate for sepsis treatment. Br J Pharmacol (2011) 0.86
Charge asymmetry in the proteins of the outer membrane. Bioinformatics (2013) 0.86
Delineation of lipopolysaccharide (LPS)-binding sites on hemoglobin: from in silico predictions to biophysical characterization. J Biol Chem (2011) 0.85
Plasticity in structure and interactions is critical for the action of indolicidin, an antibacterial peptide of innate immune origin. Protein Sci (2002) 0.84
MacA, a periplasmic membrane fusion protein of the macrolide transporter MacAB-TolC, binds lipopolysaccharide core specifically and with high affinity. J Bacteriol (2013) 0.83
N-linked glycosylation is required for c1 inhibitor-mediated protection from endotoxin shock in mice. Infect Immun (2004) 0.83
Lipopolysaccharide stabilizes the crystal packing of the ABC transporter MsbA. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.82
Life at the border: adaptation of proteins to anisotropic membrane environment. Protein Sci (2014) 0.81
A novel ML protein from Manduca sexta may function as a key accessory protein for lipopolysaccharide signaling. Mol Immunol (2008) 0.81
Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis. Proc Natl Acad Sci U S A (2016) 0.80
Antimicrobial Peptides: Insights into Membrane Permeabilization, Lipopolysaccharide Fragmentation and Application in Plant Disease Control. Sci Rep (2015) 0.80
Revisiting the interaction between the chaperone Skp and lipopolysaccharide. Biophys J (2015) 0.79
Intragenic suppressors of an OmpF assembly mutant and assessment of the roles of various OmpF residues in assembly through informational suppressors. J Bacteriol (2001) 0.78
Immunomodulatory and Anti-Inflammatory Activities of Chicken Cathelicidin-2 Derived Peptides. PLoS One (2016) 0.78
Pathogenicity of Yersinia pestis synthesis of 1-dephosphorylated lipid A. Infect Immun (2013) 0.78
Evidence of Fe3+ interaction with the plug domain of the outer membrane transferrin receptor protein of Neisseria gonorrhoeae: implications for Fe transport. Metallomics (2012) 0.78
Orientation and conformation of lipids in crystals of transmembrane proteins. Eur Biophys J (2012) 0.78
Capture of lipopolysaccharide (endotoxin) by the blood clot: a comparative study. PLoS One (2013) 0.75
Role of the Native Outer-Membrane Environment on the Transporter BtuB. Biophys J (2016) 0.75
Refinement of OprH-LPS Interactions by Molecular Simulations. Biophys J (2017) 0.75
Siderophore-mediated iron transport: crystal structure of FhuA with bound lipopolysaccharide. Science (1998) 5.62
Molecular architecture and electrostatic properties of a bacterial porin. Science (1991) 4.27
Silent embolism in diagnostic cerebral angiography and neurointerventional procedures: a prospective study. Lancet (1999) 3.20
Structural basis of light harvesting by carotenoids: peridinin-chlorophyll-protein from Amphidinium carterae. Science (1996) 3.11
Affinity chromatography of phosphofructokinase using Cibacron blue F3G-A. J Chromatogr (1972) 2.87
An improved procedure for protein staining in polyacrylamide gels with a new type of Coomassie Brilliant Blue. Anal Biochem (1972) 2.54
TonB-dependent iron acquisition: mechanisms of siderophore-mediated active transport. Mol Microbiol (1998) 2.51
Protein fusions of beta-galactosidase to the ferrichrome-iron receptor of Escherichia coli K-12. J Bacteriol (1986) 2.44
Structure of the sucrose-specific porin ScrY from Salmonella typhimurium and its complex with sucrose. Nat Struct Biol (1998) 2.39
Genetic control of hydroxamate-mediated iron uptake in Escherichia coli. J Bacteriol (1980) 2.37
Increases in cortical depth and glia numbers in rats subjected to enriched environment. J Comp Neurol (1966) 2.20
Influence of sulfide and temperature on species composition and community structure of hot spring microbial mats. Appl Environ Microbiol (2000) 2.06
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis. EMBO J (2000) 2.05
Transmembrane permeability channels across the outer membrane of Haemophilus influenzae type b. J Bacteriol (1985) 1.96
Arachnoid cysts associated with subdural hematomas and hygromas: analysis of 16 cases, long-term follow-up, and review of the literature. Neurosurgery (1997) 1.96
The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion. Cell (2000) 1.94
The three-dimensional structure of porin from Rhodobacter capsulatus at 3 A resolution. FEBS Lett (1990) 1.92
Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification. Curr Top Microbiol Immunol (1996) 1.85
Is there a benefit of preoperative meningioma embolization? Neurosurgery (2000) 1.75
Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I-69 Rd-/b+. Description of a novel deep-rough chemotype. Eur J Biochem (1988) 1.73
Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome. EMBO J (1999) 1.72
The chemical structure of bacterial endotoxin in relation to bioactivity. Immunobiology (1993) 1.69
The structure of porin from Rhodobacter capsulatus at 1.8 A resolution. FEBS Lett (1991) 1.66
Cell envelope associations of Aquaspirillum serpens flagella. J Bacteriol (1978) 1.66
Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore. FEBS Lett (1996) 1.62
Förster excitation energy transfer in peridinin-chlorophyll-a-protein. Biophys J (2000) 1.62
Deletion of the heptosyltransferase genes rfaC and rfaF in Escherichia coli K-12 results in an Re-type lipopolysaccharide with a high degree of 2-aminoethanol phosphate substitution. Eur J Biochem (1997) 1.51
Structural characterization of the lipid A component of Helicobacter pylori rough- and smooth-form lipopolysaccharides. J Bacteriol (1997) 1.49
Induced-fit movements in adenylate kinases. J Mol Biol (1990) 1.49
Retracted The remarkable cochlear amplifier. Hear Res (2010) 1.47
Refined crystal structure and mutagenesis of human granulocyte-macrophage colony-stimulating factor. Proteins (1996) 1.47
Structural characterization of the lipid A component of pathogenic Neisseria meningitidis. J Bacteriol (1992) 1.46
Differentiation between intracerebral hemorrhage and ischemic stroke by transcranial color-coded duplex-sonography. Stroke (1998) 1.45
The ABC maltose transporter. Mol Microbiol (1998) 1.44
Molecular mechanisms of polymyxin B-membrane interactions: direct correlation between surface charge density and self-promoted transport. J Membr Biol (1998) 1.43
fhuC and fhuD genes for iron (III)-ferrichrome transport into Escherichia coli K-12. J Bacteriol (1987) 1.41
The x-ray structure of D-amino acid oxidase at very high resolution identifies the chemical mechanism of flavin-dependent substrate dehydrogenation. Proc Natl Acad Sci U S A (2000) 1.41
Radiation oncology training in Poland: results of a national survey (2007). Clin Oncol (R Coll Radiol) (2008) 1.40
Characterization of lipopolysaccharides of polymyxin-resistant and polymyxin-sensitive Klebsiella pneumoniae O3. Eur J Biochem (1996) 1.39
Crystal structure of Omp32, the anion-selective porin from Comamonas acidovorans, in complex with a periplasmic peptide at 2.1 A resolution. Structure (2000) 1.39
The lipopolysaccharide of Legionella pneumophila serogroup 1 (strain Philadelphia 1): chemical structure and biological significance. Prog Clin Biol Res (1995) 1.37
[Reciprocity of yeast-phosphofructokinase with dextran blue 2000]. Eur J Biochem (1971) 1.31
Molecular structure of lipid A, the endotoxic center of bacterial lipopolysaccharides. Adv Carbohydr Chem Biochem (1994) 1.31
Ligand-induced conformational change in the ferrichrome-iron receptor of Escherichia coli K-12. Mol Microbiol (1996) 1.29
Sequencing of porA from clinical isolates of Neisseria meningitidis defines a subtyping scheme and its genetic regulation. Can J Microbiol (1998) 1.29
Vulnerability of the nigrostriatal system as detected by transcranial ultrasound. Neurology (1999) 1.27
Tertiary structure of Staphylococcus aureus cell wall murein. J Bacteriol (2004) 1.27
Efficacy of trisacryl gelatin microspheres versus polyvinyl alcohol particles in the preoperative embolization of meningiomas. AJNR Am J Neuroradiol (2000) 1.27
Crystal structure of the antibiotic albomycin in complex with the outer membrane transporter FhuA. Protein Sci (2000) 1.27
Use of an oncolytic vaccinia virus for the treatment of canine breast cancer in nude mice: preclinical development of a therapeutic agent. Cancer Gene Ther (2008) 1.26
Cell envelope signaling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor fhua promotes interaction with the energy-transducing protein TonB. J Biol Chem (1997) 1.26
Carbohydrate-binding modules from a thermostable Rhodothermus marinus xylanase: cloning, expression and binding studies. Biochem J (2000) 1.26
Iron supply of Escherichia coli with polymer-bound ferricrocin. Eur J Biochem (1979) 1.24
Peridinin chlorophyll a protein: relating structure and steady-state spectroscopy. Biochemistry (2000) 1.24
Polygraphic studies of normal infants during the first six months of life: III. Incidence of apnea and periodic breathing. Pediatrics (1977) 1.23
Structural characterization of the lipid A component of Pseudomonas aeruginosa wild-type and rough mutant lipopolysaccharides. Eur J Biochem (1991) 1.23
Properties of the porin of Haemophilus influenzae type b in planar lipid bilayer membranes. Biochim Biophys Acta (1986) 1.23
Host-response patterns of intramammary infections in dairy cows. Vet Immunol Immunopathol (2011) 1.23
Genetic insertion and exposure of a reporter epitope in the ferrichrome-iron receptor of Escherichia coli K-12. J Bacteriol (1994) 1.22
The outer membrane of haemophilus influenzae type b: cell envelope associations of major proteins. Can J Microbiol (1983) 1.22
Occurrence of antibodies against chlamydial lipopolysaccharide in human sera as measured by ELISA using an artificial glycoconjugate antigen. FEMS Immunol Med Microbiol (1994) 1.20
Molecular cloning of the ferrichrome-iron receptor of Escherichia coli K-12. J Bacteriol (1983) 1.17
Brucella abortus and its closest phylogenetic relative, Ochrobactrum spp., differ in outer membrane permeability and cationic peptide resistance. Infect Immun (2000) 1.17
Studies on the size and composition of the isolated light-harvesting B800-850 pigment-protein complex of Rhodopseudomonas capsulata. Arch Biochem Biophys (1982) 1.17
Do arachnoid cysts grow? A retrospective CT volumetric study. Neuroradiology (1991) 1.16
The crystal structure of a liganded trehalose/maltose-binding protein from the hyperthermophilic Archaeon Thermococcus litoralis at 1.85 A. J Mol Biol (2001) 1.15
Antigenic sites on porin of Haemophilus influenzae type b: mapping with synthetic peptides and evaluation of structure predictions. J Bacteriol (1992) 1.15
Firing statistics of a neuron model driven by long-range correlated noise. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 1.14
Internal deletions in the FhuA receptor of Escherichia coli K-12 define domains of ligand interactions. J Bacteriol (1991) 1.13
The ferrichrome-iron receptor of Escherichia coli K-12. Antigenicity of the fhuA protein. Biochim Biophys Acta (1982) 1.13
Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide. Infect Immun (1990) 1.12
Isolation and structural analysis of two lipid A precursors from a KDO deficient mutant of Salmonella typhimurium differing in their hexadecanoic acid content. Arch Microbiol (1985) 1.11
Non-lamellar structure and negative charges of lipopolysaccharides required for efficient folding of outer membrane protein PhoE of Escherichia coli. J Biol Chem (1999) 1.11
Solid-cystic (papillary-cystic) tumours within and outside the pancreas in men: report of two patients. Virchows Arch A Pathol Anat Histopathol (1991) 1.10
Novel processive and nonprocessive glycosyltransferases from Staphylococcus aureus and Arabidopsis thaliana synthesize glycoglycerolipids, glycophospholipids, glycosphingolipids and glycosylsterols. Eur J Biochem (2000) 1.09
Outer membrane porin protein of Haemophilus influenzae type b: pore size and subunit structure. Can J Microbiol (1988) 1.09
Chemical structure and biologic activity of bacterial and synthetic lipid A. Rev Infect Dis (1988) 1.09
Structural studies on the phosphate-free lipid A of Rhodomicrobium vannielii ATCC 17100. Eur J Biochem (1983) 1.08
The permeability barrier of Haemophilus influenzae type b against beta-lactam antibiotics. J Antimicrob Chemother (1983) 1.07
Structural studies on the lipid A component of enterobacterial lipopolysaccharides by laser desorption mass spectrometry. Location of acyl groups at the lipid A backbone. Eur J Biochem (1984) 1.07
The influence of heptane-1,2,3-triol on the size and shape of LDAO micelles. Implications for the crystallisation of membrane proteins. FEBS Lett (1991) 1.07
Crystallization of the human, mitochondrial voltage-dependent anion-selective channel in the presence of phospholipids. J Struct Biol (1999) 1.07
Nature and location of amide-bound (R)-3-acyloxyacyl groups in lipid A of lipopolysaccharides from various gram-negative bacteria. Eur J Biochem (1984) 1.06
The significance of phosphofructokinase to the regulation of carbohydrate metabolism. Rev Physiol Biochem Pharmacol (1976) 1.06
Characterization of a novel lipid A containing D-galacturonic acid that replaces phosphate residues. The structure of the lipid a of the lipopolysaccharide from the hyperthermophilic bacterium Aquifex pyrophilus. J Biol Chem (2000) 1.06
Parkinson's disease and depression: evidence for an alteration of the basal limbic system detected by transcranial sonography. J Neurol Neurosurg Psychiatry (1997) 1.05
Prokaryotic triterpenoids. The hopanoids of the purple non-sulphur bacterium Rhodomicrobium vannielii: an aminotriol and its aminoacyl derivatives, N-tryptophanyl and N-ornithinyl aminotriol. Eur J Biochem (1985) 1.05