PubRank

R N DuBois

Author PubWeight™ 139.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 1996 10.49
2 Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 1994 8.79
3 The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med 2000 7.54
4 Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998 7.25
5 Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 1995 6.69
6 The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999 5.50
7 Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci U S A 1997 4.84
8 Modulation of apoptosis and Bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 1998 3.79
9 Prostaglandin E2 increases growth and motility of colorectal carcinoma cells. J Biol Chem 2001 3.40
10 Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth. Gastroenterology 2001 3.13
11 Host cyclooxygenase-2 modulates carcinoma growth. J Clin Invest 2000 3.03
12 Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2. J Clin Invest 1997 2.99
13 Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells. J Biol Chem 1997 2.66
14 Cyclo-oxygenase-2-derived prostacyclin mediates embryo implantation in the mouse via PPARdelta. Genes Dev 1999 2.37
15 Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer. Proc Natl Acad Sci U S A 2000 2.23
16 Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells. Proc Natl Acad Sci U S A 1997 2.12
17 Celecoxib prevents tumor growth in vivo without toxicity to normal gut: lack of correlation between in vitro and in vivo models. Cancer Res 2000 2.05
18 Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996 1.91
19 Transforming growth factor-beta1 enhances Ha-ras-induced expression of cyclooxygenase-2 in intestinal epithelial cells via stabilization of mRNA. J Biol Chem 2000 1.77
20 Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) mice. Gastroenterology 2000 1.75
21 Elevated cyclooxygenase-2 levels in Min mouse adenomas. Gastroenterology 1996 1.65
22 Colorectal cancer and nonsteroidal anti-inflammatory drugs. Adv Pharmacol 1997 1.63
23 Regulation of constitutive cyclooxygenase-2 expression in colon carcinoma cells. J Biol Chem 2000 1.58
24 Target genes of peroxisome proliferator-activated receptor gamma in colorectal cancer cells. J Biol Chem 2001 1.48
25 Global gene expression analysis to identify molecular markers of uterine receptivity and embryo implantation. J Biol Chem 2001 1.43
26 A selective cyclooxygenase 2 inhibitor suppresses the growth of H-ras-transformed rat intestinal epithelial cells. Gastroenterology 1997 1.35
27 The role of nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. Eur J Cancer 1995 1.32
28 Aspirin use and potential mechanisms for colorectal cancer prevention. J Clin Invest 1997 1.25
29 Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway. J Biol Chem 1998 1.24
30 Differential expression of matrilysin and cyclooxygenase-2 in intestinal and colorectal neoplasms. Mol Carcinog 1999 1.23
31 Concurrent overexpression of cyclin D1 and cyclin-dependent kinase 4 (Cdk4) in intestinal adenomas from multiple intestinal neoplasia (Min) mice and human familial adenomatous polyposis patients. Cancer Res 1997 1.23
32 Detection of differentially expressed genes in human colon carcinoma cells treated with a selective COX-2 inhibitor. Oncogene 2001 1.20
33 Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch Biochem Biophys 1995 1.20
34 Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells. J Biol Chem 2001 1.20
35 Heightened expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-delta in human endometrial adenocarcinoma. Neoplasia 2001 1.18
36 Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas. Carcinogenesis 1998 1.16
37 Prostaglandin levels in human colorectal mucosa: effects of sulindac in patients with familial adenomatous polyposis. Dig Dis Sci 1998 1.15
38 Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells. Gastroenterology 2000 1.13
39 Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading. J Biol Chem 1992 1.12
40 Aspirin, NSAIDS, and colon cancer prevention: mechanisms? Gastroenterology 1998 1.11
41 Reduced COX-2 protein in colorectal cancer with defective mismatch repair. Cancer Res 1998 1.09
42 Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. J Biol Chem 2000 1.09
43 Cloning, expression, and regulation of rabbit cyclooxygenase-2 in renal medullary interstitial cells. Am J Physiol 1997 1.09
44 Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors. Carcinogenesis 1999 1.07
45 A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2. Clin Cancer Res 2001 1.04
46 The catalytic outcomes of the constitutive and the mitogen inducible isoforms of prostaglandin H2 synthase are markedly affected by glutathione and glutathione peroxidase(s). Biochemistry 1995 1.03
47 A cyclooxygenase-2 inhibitor (SC-58125) blocks growth of established human colon cancer xenografts. Neoplasia 2001 0.99
48 Activation of peroxisome proliferator-activated receptor gamma suppresses nuclear factor kappa B-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. J Biol Chem 2001 0.98
49 Posttranscriptional regulation of cyclooxygenase-2 in rat intestinal epithelial cells. Neoplasia 2001 0.98
50 Meloxicam inhibits the growth of colorectal cancer cells. Carcinogenesis 1998 0.97
51 Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase. J Biol Chem 1993 0.96
52 The role of COX-2 in intestinal cancer. Ann N Y Acad Sci 1999 0.96
53 Induction of synthesis of cholesterol side chain cleavage cytochrome P-450 by adrenocorticotropin in cultured bovine adrenocortical cells. J Biol Chem 1981 0.95
54 Cyclooxygenase-2 induction and transforming growth factor beta growth inhibition in rat intestinal epithelial cells. Cell Growth Differ 1997 0.94
55 Nonsteroidal anti-inflammatory drugs and prevention of colorectal cancer. Curr Gastroenterol Rep 1999 0.93
56 Sulindac sulfide, but not sulindac sulfone, inhibits colorectal cancer growth. Neoplasia 1999 0.90
57 Eicosanoids and the large intestine. Prostaglandins Other Lipid Mediat 2000 0.89
58 Decreased transforming growth factor beta type II receptor expression in intestinal adenomas from Min/+ mice is associated with increased cyclin D1 and cyclin-dependent kinase 4 expression. Cancer Res 1997 0.88
59 Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2. Oncogene 1999 0.88
60 Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells. Proc Natl Acad Sci U S A 1981 0.88
61 Inhibition of heat-shock protein 70 induction in intestinal cells overexpressing cyclooxygenase 2. Gastroenterology 1998 0.86
62 The role of COX-2 in intestinal cancer. Expert Opin Investig Drugs 1999 0.84
63 Combinations for cancer prevention. Nat Med 2000 0.84
64 Role of cyclooxygenase inhibitors for the prevention of colorectal cancer. Gastroenterol Clin North Am 2001 0.82
65 Regulation of 12-lipoxygenase in rat intestinal epithelial cells during differentiation and apoptosis induced by sodium butyrate. Arch Biochem Biophys 1999 0.82
66 In vivo immediate early gene expression induced in intestinal and colonic mucosa by feeding. FEBS Lett 1991 0.81
67 Translational studies on Cox-2 inhibitors in the prevention and treatment of colon cancer. Ann N Y Acad Sci 2000 0.81
68 The molecular basis for prevention of colorectal cancer. Clin Colorectal Cancer 2001 0.80
69 Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction. Br J Cancer 2003 0.80
70 Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells. Oncogene 2011 0.80
71 Regulation of cyclo-oxygenase-2. Best Pract Res Clin Gastroenterol 2001 0.79
72 Nonsteroidal anti-inflammatory drug use and sporadic colorectal adenomas. Gastroenterology 1995 0.79
73 The molecular basis of colorectal carcinogenesis. Curr Opin Gastroenterol 1999 0.77
74 Analysis of the effect of COX-2 specific inhibitors and recommendations for their use in clinical practice. J Rheumatol 2000 0.77
75 Antioxidant effect of acetaminophen in rat liver. Biochem Pharmacol 1983 0.76
76 Cyclooxygenease-2 and hepatocellular carcinoma: is it a target for prevention? Clin Cancer Res 2001 0.75
77 Altered heme environments in opossum and rabbit methemoglobins. Z Naturforsch C 1982 0.75
78 Current concepts in colorectal cancer prevention. Compr Ther 1997 0.75
79 Induction of rabbit cyclooxygenase 2 in the anterior uvea following glaucoma filtration surgery. Curr Eye Res 1997 0.75