Published in Immunity on June 01, 2000
Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1. Nat Genet (2007) 6.83
Concerted and birth-and-death evolution of multigene families. Annu Rev Genet (2005) 6.37
Activation, coactivation, and costimulation of resting human natural killer cells. Immunol Rev (2006) 3.30
The Yin and Yang of HLA and KIR in human disease. Semin Immunol (2008) 2.72
KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C. J Exp Med (2009) 1.99
Comparative genomics of natural killer cell receptor gene clusters. PLoS Genet (2005) 1.85
The extensive polymorphism of KIR genes. Immunology (2010) 1.83
Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function. Immunity (2015) 1.71
DNA methylation maintains allele-specific KIR gene expression in human natural killer cells. J Exp Med (2003) 1.70
Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates. Genome Res (2005) 1.56
Human-specific evolution of killer cell immunoglobulin-like receptor recognition of major histocompatibility complex class I molecules. Philos Trans R Soc Lond B Biol Sci (2012) 1.55
Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes. Genome Res (2009) 1.42
Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster. Proc Natl Acad Sci U S A (2001) 1.40
The genetic and evolutionary balances in human NK cell receptor diversity. Semin Immunol (2008) 1.35
Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy. J Immunol (2008) 1.35
Identification of a single killer immunoglobulin-like receptor (KIR) gene in the porcine leukocyte receptor complex on chromosome 6q. Immunogenetics (2006) 1.26
KIR/HLA interactions and pathogen immunity. J Biomed Biotechnol (2011) 1.26
Methods for assessing gene content diversity of KIR with examples from a global set of populations. Immunogenetics (2008) 1.22
DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors. Clin Immunol (2008) 1.21
Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I. J Immunol (2010) 1.20
The D0 domain of KIR3D acts as a major histocompatibility complex class I binding enhancer. J Exp Med (2002) 1.19
Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cells. PLoS Genet (2010) 1.16
SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex. Immunogenetics (2004) 1.15
Primate-specific regulation of natural killer cells. J Med Primatol (2010) 1.14
Paired Ig-like receptor homologs in birds and mammals share a common ancestor with mammalian Fc receptors. Proc Natl Acad Sci U S A (2000) 1.14
Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes. J Immunol (2009) 1.12
Identification of NKG2A and NKp80 as specific natural killer cell markers in rhesus and pigtailed monkeys. Blood (2005) 1.11
Killer cell immunoglobulin-like receptor (KIR) gene content variation in the HGDP-CEPH populations. Immunogenetics (2012) 1.11
KIR haplotypes defined by segregation analysis in 59 Centre d'Etude Polymorphisme Humain (CEPH) families. Immunogenetics (2008) 1.10
Coevolution of killer cell Ig-like receptors with HLA-C to become the major variable regulators of human NK cells. J Immunol (2010) 1.09
The mosaic of KIR haplotypes in rhesus macaques. Immunogenetics (2010) 1.07
Identification of the mouse killer immunoglobulin-like receptor-like (Kirl) gene family mapping to chromosome X. Immunogenetics (2003) 1.03
Expression breadth and expression abundance behave differently in correlations with evolutionary rates. BMC Evol Biol (2010) 1.03
Comparison of the rapidly evolving KIR locus in Parsis and natives of India. Immunogenetics (2008) 1.02
The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci. PLoS Genet (2006) 1.01
A small, variable, and irregular killer cell Ig-like receptor locus accompanies the absence of MHC-C and MHC-G in gibbons. J Immunol (2009) 1.00
Molecular characterization of KIR3DL3. Immunogenetics (2006) 1.00
Susceptibility to Crohn's disease is mediated by KIR2DL2/KIR2DL3 heterozygosity and the HLA-C ligand. Immunogenetics (2009) 1.00
Diverse functionality among human NK cell receptors for the C1 epitope of HLA-C: KIR2DS2, KIR2DL2, and KIR2DL3. Front Immunol (2012) 0.99
Identification of the ancestral killer immunoglobulin-like receptor gene in primates. BMC Genomics (2006) 0.99
Ly49 genes in non-rodent mammals. Immunogenetics (2003) 0.98
Short KIR haplotypes in pygmy chimpanzee (Bonobo) resemble the conserved framework of diverse human KIR haplotypes. J Exp Med (2001) 0.98
Review: Immunogenetics of human placentation. Placenta (2011) 0.92
The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia. Blood (2014) 0.92
The evolution of natural killer cell receptors. Immunogenetics (2015) 0.92
Evidence for balancing selection acting on KIR2DL4 genotypes in rhesus macaques of Indian origin. Immunogenetics (2009) 0.90
KIR3DL01 recognition of Bw4 ligands in the rhesus macaque: maintenance of Bw4 specificity since the divergence of apes and Old World monkeys. J Immunol (2014) 0.90
Suggestive association of major histocompatibility IB genetic markers with resistance to bacterial cold water disease in rainbow trout (Oncorhynchus mykiss). Mar Biotechnol (NY) (2008) 0.88
Thirty allele-level haplotypes centered around KIR2DL5 define the diversity in an African American population. Immunogenetics (2010) 0.88
Natural killer cells and their receptors in multiple sclerosis. Brain (2012) 0.87
The structural basis of ligand recognition by natural killer cell receptors. J Biomed Biotechnol (2011) 0.87
KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression. Front Immunol (2012) 0.86
Chain-terminating natural mutations affect the function of activating KIR receptors 3DS1 and 2DS3. Immunogenetics (2007) 0.86
Co-evolution of MHC class I and variable NK cell receptors in placental mammals. Immunol Rev (2015) 0.85
Opportunities and limitations of natural killer cells as adoptive therapy for malignant disease. Cytotherapy (2014) 0.85
DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3. Immunogenetics (2003) 0.84
Although divergent in residues of the peptide binding site, conserved chimpanzee Patr-AL and polymorphic human HLA-A*02 have overlapping peptide-binding repertoires. J Immunol (2011) 0.84
The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolution. BMC Evol Biol (2008) 0.83
Polymorphism of two very similar MHC class Ib loci in rainbow trout (Oncorhynchus mykiss). Immunogenetics (2006) 0.83
Robustness and evolvability of the human signaling network. PLoS Comput Biol (2014) 0.82
AIDS in chimpanzees: the role of MHC genes. Immunogenetics (2017) 0.80
Paired opposing leukocyte receptors recognizing rapidly evolving ligands are subject to homogenization of their ligand binding domains. Immunogenetics (2011) 0.80
Co-evolution of the MHC class I and KIR gene families in rhesus macaques: ancestry and plasticity. Immunol Rev (2015) 0.80
KIR and HLA under pressure: evidences of coevolution across worldwide populations. Hum Genet (2015) 0.79
Deciphering the KIR system at super-resolution for NK and T cell biology. Immunology (2016) 0.79
Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations. Immunogenetics (2010) 0.78
The basis for haplotype complexity in VCBPs, an immune-type receptor in amphioxus. Immunogenetics (2010) 0.78
Natural killer cell function and dysfunction in hepatitis C virus infection. Biomed Res Int (2014) 0.77
Mechanisms of cell-mediated myocytotoxicity in the peripheral blood of patients with inflammatory myopathies. J Clin Immunol (2001) 0.76
Multigene families of immunoglobulin domain-containing innate immune receptors in zebrafish: deciphering the differences. Dev Comp Immunol (2014) 0.76
Identification and diversity of killer cell Ig-like receptors in Aotus vociferans, a New World monkey. PLoS One (2013) 0.75
Influence of host resistance on viral adaptation: hepatitis C virus as a case study. Infect Drug Resist (2015) 0.75
The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes. Genes Immun (2016) 0.75
Two Orangutan Species Have Evolved Different KIR Alleles and Haplotypes. J Immunol (2017) 0.75
Chimpanzee susceptibility to hepatitis C virus infection correlates with presence of Pt-KIR3DS2 and Pt-KIR2DL9: paired activating and inhibitory natural killer cell receptors. Immunogenetics (2015) 0.75
The Impact of HLA Class I-Specific Killer Cell Immunoglobulin-Like Receptors on Antibody-Dependent Natural Killer Cell-Mediated Cytotoxicity and Organ Allograft Rejection. Front Immunol (2016) 0.75
Pas de deux: natural killer receptors and MHC class I ligands in primates. Curr Genomics (2007) 0.75
Age- and Sex-associated Differences in Phenotypic and Functional Characteristics of Peripheral Blood Lymphocytes in Chimpanzees (Pan troglodytes). J Am Assoc Lab Anim Sci (2017) 0.75
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science (1999) 11.04
Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain. Science (1989) 9.01
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med (1992) 8.27
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med (1993) 8.03
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 7.12
Monoclonal antibodies for analysis of the HLA system. Immunol Rev (1979) 6.63
Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens. J Immunol (1983) 6.39
Analysis of a successful immune response against hepatitis C virus. Immunity (1999) 6.31
Immune inhibitory receptors. Science (2000) 6.05
Pictures of MHC restriction. Nature (1996) 6.04
The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J Immunol (1986) 5.27
Use of a monoclonal antibody (W6/32) in structural studies of HLA-A,B,C, antigens. J Immunol (1979) 5.06
Human diversity in killer cell inhibitory receptor genes. Immunity (1997) 4.82
An activating immunoreceptor complex formed by NKG2D and DAP10. Science (1999) 4.56
Natural killer cells, viruses and cancer. Nat Rev Immunol (2001) 4.21
Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem (1990) 4.02
Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis. J Exp Med (1986) 3.99
Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity (2000) 3.84
Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity (1997) 3.84
Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med (1989) 3.70
CD28- T lymphocytes. Antigenic and functional properties. J Immunol (1993) 3.67
B70 antigen is a second ligand for CTLA-4 and CD28. Nature (1993) 3.57
On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice. J Immunol (1983) 3.57
Nomenclature for the major histocompatibility complexes of different species: a proposal. Immunogenetics (1990) 3.53
The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. J Exp Med (1995) 3.43
IMGT/HLA database--a sequence database for the human major histocompatibility complex. Tissue Antigens (2000) 3.41
Applications of retrovirus-mediated expression cloning. Exp Hematol (1996) 3.40
Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts. Nat Genet (2000) 3.39
Guilt by association: HLA-B27 and ankylosing spondylitis. Immunol Today (1990) 3.38
Monoclonal antibodies against rat immunoglobulin kappa chains. Hybridoma (1982) 3.36
Comparative studies of human FcRIII-positive and negative natural killer cells. J Immunol (1989) 3.28
Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens. Eur J Immunol (1979) 3.27
Nomenclature for factors of the HLA system, 2010. Tissue Antigens (2010) 3.22
Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor in vivo. Proc Natl Acad Sci U S A (2001) 3.21
HLA-A and B polymorphisms predate the divergence of humans and chimpanzees. Nature (1988) 3.21
Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28. Hum Immunol (1981) 3.01
Monoclonal antibody to a human histocompatibility alloantigen, HLA-A2. Nature (1978) 2.93
Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition. J Immunol (1998) 2.79
Immunology. Deconstructing the MHC. Nature (1992) 2.76
DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming. Immunity (2000) 2.75
Monomorphic anti-HLA-A,B,C monoclonal antibodies detecting molecular subunits and combinatorial determinants. J Immunol (1982) 2.74
Structure of HLA antigens: amino-acid and carbohydrate compositions and NH2-terminal sequences of four antigen preparations. Proc Natl Acad Sci U S A (1976) 2.71
CD28 interaction with B7 costimulates primary allogeneic proliferative responses and cytotoxicity mediated by small, resting T lymphocytes. J Exp Med (1992) 2.70
The Fc receptor for IgG on human natural killer cells: phenotypic, functional, and comparative studies with monoclonal antibodies. J Immunol (1984) 2.70
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes. Nat Immunol (2000) 2.66
Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol (1995) 2.63
NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J Exp Med (1994) 2.59
DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 2.56
A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17. Hum Immunol (1980) 2.56
The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. J Exp Med (1987) 2.52
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J Exp Med (1994) 2.47
Natural killer cells: definition of a cell type rather than a function. J Immunol (1986) 2.46
Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science (1995) 2.44
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics (2001) 2.43
Rapid cloning of HLA-A,B cDNA by using the polymerase chain reaction: frequency and nature of errors produced in amplification. Proc Natl Acad Sci U S A (1990) 2.37
Monoclonal antibodies: purification, fragmentation and application to structural and functional studies of class I MHC antigens. J Immunol Methods (1982) 2.35
Carbohydrate moiety of HLA antigens. Antigenic properties and amino acid sequences around the site of glycosylation. J Biol Chem (1977) 2.30
The HLA-A,B "negative" mutant cell line C1R expresses a novel HLA-B35 allele, which also has a point mutation in the translation initiation codon. J Immunol (1992) 2.27
Cell-cell adhesion mediated by CD8 and MHC class I molecules. Nature (1988) 2.25
Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens. J Immunol (1985) 2.20
Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus. Nature (1987) 2.20
IMGT/HLA Database--a sequence database for the human major histocompatibility complex. Nucleic Acids Res (2001) 2.17
A binding site for the T-cell co-receptor CD8 on the alpha 3 domain of HLA-A2. Nature (1990) 2.17
Structure, function, and serology of the T-cell antigen receptor complex. Annu Rev Immunol (1987) 2.17
p150/95, Third member of the LFA-1/CR3 polypeptide family identified by anti-Leu M5 monoclonal antibody. Eur J Immunol (1985) 2.14
B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells. J Exp Med (1994) 2.14
Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J Immunol (1996) 2.13
Cutting edge: the mouse NK cell-associated antigen recognized by DX5 monoclonal antibody is CD49b (alpha 2 integrin, very late antigen-2). J Immunol (2001) 2.09
Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. J Immunol (1998) 2.06
Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation. Prog Growth Factor Res (1992) 2.05
Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism. J Immunol (2001) 2.02
Human natural killer cells isolated from peripheral blood do not rearrange T cell antigen receptor beta chain genes. J Exp Med (1986) 2.01
Nomenclature for factors of the HLA system, 1990. Tissue Antigens (1991) 1.98
Functional expression of B7/BB1 on activated T lymphocytes. J Exp Med (1993) 1.98
Activation of natural killer cells via the p75 interleukin 2 receptor. J Exp Med (1989) 1.95
Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites. Proc Natl Acad Sci U S A (1979) 1.94
Heavy chain of HLA-A and HLA-B antigens is conformationally labile: a possible role for beta 2-microglobulin. Proc Natl Acad Sci U S A (1979) 1.93
Specificity of HLA class I antigen recognition by human NK clones: evidence for clonal heterogeneity, protection by self and non-self alleles, and influence of the target cell type. J Exp Med (1993) 1.93
Location and distribution of the light chains in clathrin trimers. Proc Natl Acad Sci U S A (1983) 1.90
Nomenclature for factors of the HLA system, 2002. Tissue Antigens (2002) 1.89
Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments. Nature (1987) 1.89
Ligands for natural killer cell receptors: redundancy or specificity. Immunol Rev (2001) 1.88
Relative contribution of the leukocyte molecules Mo1, LFA-1, and p150,95 (LeuM5) in adhesion of granulocytes and monocytes to vascular endothelium is tissue- and stimulus-specific. J Cell Physiol (1988) 1.88
Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity (1996) 1.87
Evolution of class-I MHC genes and proteins: from natural selection to thymic selection. Annu Rev Immunol (1990) 1.87
Conserved and variable residues within the Bw4 motif of HLA-B make separable contributions to recognition by the NKB1 killer cell-inhibitory receptor. J Immunol (1997) 1.86
Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells. Proc Natl Acad Sci U S A (1999) 1.86