Published in Genes Dev on July 15, 2000
The transcription factor Sox10 is a key regulator of peripheral glial development. Genes Dev (2001) 4.40
Molecular dissection of mesenchymal-epithelial interactions in the hair follicle. PLoS Biol (2005) 4.27
The basic helix-loop-helix protein family: comparative genomics and phylogenetic analysis. Genome Res (2001) 2.47
Genome-wide analysis of basic/helix-loop-helix transcription factor family in rice and Arabidopsis. Plant Physiol (2006) 2.25
Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. J Cell Biol (2002) 2.00
Main roads to melanoma. J Transl Med (2009) 1.67
The metallochaperone Atox1 plays a critical role in perinatal copper homeostasis. Proc Natl Acad Sci U S A (2001) 1.45
Assembly of the cnidarian camera-type eye from vertebrate-like components. Proc Natl Acad Sci U S A (2008) 1.43
Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells. PLoS Genet (2015) 1.43
Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling. EMBO J (2002) 1.37
Signaling pathways in melanosome biogenesis and pathology. Int J Biochem Cell Biol (2010) 1.27
The Brn-2 transcription factor links activated BRAF to melanoma proliferation. Mol Cell Biol (2004) 1.24
Pharmacologic suppression of MITF expression via HDAC inhibitors in the melanocyte lineage. Pigment Cell Melanoma Res (2008) 1.21
Preclinical studies of celastrol and acetyl isogambogic acid in melanoma. Clin Cancer Res (2007) 1.20
The Fugu tyrp1 promoter directs specific GFP expression in zebrafish: tools to study the RPE and the neural crest-derived melanophores. Pigment Cell Res (2006) 1.17
The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res (2008) 1.16
Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate. Proc Natl Acad Sci U S A (2009) 1.15
Malignant melanoma in the 21st century: the emerging molecular landscape. Mayo Clin Proc (2008) 1.13
MITF mediates cAMP-induced protein kinase C-beta expression in human melanocytes. Biochem J (2006) 1.11
Understanding signaling cascades in melanoma. Photochem Photobiol (2007) 1.10
Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin. Mol Cell Biol (2004) 1.09
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms. Am J Pathol (2001) 1.08
Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res (2009) 1.07
The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a. Mol Cancer (2009) 1.06
A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Proc Natl Acad Sci U S A (2009) 1.04
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells. Elife (2015) 1.03
The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis. Genes Dev (2005) 1.02
The Tyr (albino) locus of the laboratory mouse. Mamm Genome (2004) 1.00
Interspecies difference in the regulation of melanocyte development by SOX10 and MITF. Proc Natl Acad Sci U S A (2006) 0.99
The basic helix-loop-helix leucine zipper transcription factor Mitf is conserved in Drosophila and functions in eye development. Genetics (2004) 0.98
A dynamic code of dorsal neural tube genes regulates the segregation between neurogenic and melanogenic neural crest cells. Development (2013) 0.97
Expression of microtubule-associated protein 2 in benign and malignant melanocytes: implications for differentiation and progression of cutaneous melanoma. Am J Pathol (2001) 0.97
MITF in melanoma: mechanisms behind its expression and activity. Cell Mol Life Sci (2014) 0.97
Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation. J Biol Chem (2005) 0.96
Selective down-regulation of tyrosinase family gene TYRP1 by inhibition of the activity of melanocyte transcription factor, MITF. Nucleic Acids Res (2002) 0.95
SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium. J Biol Chem (2010) 0.95
Regeneration of neural crest derivatives in the Xenopus tadpole tail. BMC Dev Biol (2007) 0.95
FGF2 regulates melanocytes viability through the STAT3-transactivated PAX3 transcription. Cell Death Differ (2011) 0.93
BEST1 expression in the retinal pigment epithelium is modulated by OTX family members. Hum Mol Genet (2008) 0.93
Heterogeneity of expression of epithelial-mesenchymal transition markers in melanocytes and melanoma cell lines. Front Genet (2013) 0.93
Inhibition of melanogenesis by gallic acid: possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells. Int J Mol Sci (2013) 0.92
A novel isoform of microphthalmia-associated transcription factor inhibits IL-8 gene expression in human cervical stromal cells. Mol Endocrinol (2010) 0.92
Klotho regulates retinal pigment epithelial functions and protects against oxidative stress. J Neurosci (2013) 0.91
Macrophage inhibitory cytokine-1 regulates melanoma vascular development. Am J Pathol (2010) 0.91
Transport activity and presence of ClC-7/Ostm1 complex account for different cellular functions. EMBO Rep (2014) 0.88
Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics (2015) 0.87
Comparison of Gene Expression Profiles between Keratinocytes, Melanocytes and Fibroblasts. Ann Dermatol (2013) 0.86
The role of phenotypic plasticity in the escape of cancer cells from targeted therapy. Biochem Pharmacol (2016) 0.86
Networks and pathways in pigmentation, health, and disease. Wiley Interdiscip Rev Syst Biol Med (2010) 0.86
Mitf-Mdel, a novel melanocyte/melanoma-specific isoform of microphthalmia-associated transcription factor-M, as a candidate biomarker for melanoma. BMC Med (2010) 0.85
Dipeptides Inhibit Melanin Synthesis in Mel-Ab Cells through Down-Regulation of Tyrosinase. Korean J Physiol Pharmacol (2012) 0.83
High-level activation of cyclic AMP signaling attenuates bone morphogenetic protein 2-induced sympathoadrenal lineage development and promotes melanogenesis in neural crest cultures. Mol Cell Biol (2005) 0.83
Episodic Src activation in uveal melanoma revealed by kinase activity profiling. Br J Cancer (2009) 0.83
Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention. Oncotarget (2013) 0.83
Functional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity. Nucleic Acids Res (2003) 0.82
The melanocyte inducing factor MITF is stably expressed in cell lines from human clear cell sarcoma. Br J Cancer (2003) 0.82
Overexpression of EcbHLH57 Transcription Factor from Eleusine coracana L. in Tobacco Confers Tolerance to Salt, Oxidative and Drought Stress. PLoS One (2015) 0.81
CtBP2 downregulation during neural crest specification induces expression of Mitf and REST, resulting in melanocyte differentiation and sympathoadrenal lineage suppression. Mol Cell Biol (2011) 0.81
MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells. PLoS One (2013) 0.81
TBX2 expression is regulated by PAX3 in the melanocyte lineage. Pigment Cell Melanoma Res (2012) 0.81
Antagonistic cross-regulation between Sox9 and Sox10 controls an anti-tumorigenic program in melanoma. PLoS Genet (2015) 0.81
Genome-wide analysis of bHLH transcription factor and involvement in the infection by yellow leaf curl virus in tomato (Solanum lycopersicum). BMC Genomics (2015) 0.81
Extrafollicular dermal melanocyte stem cells and melanoma. Stem Cells Int (2012) 0.80
Role of BMP-4 and Its Signaling Pathways in Cultured Human Melanocytes. Int J Cell Biol (2009) 0.80
SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma. Crit Rev Eukaryot Gene Expr (2014) 0.80
Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to melanotic by inhibition of AKT. Neoplasia (2006) 0.80
The Genetics of Deafness in Domestic Animals. Front Vet Sci (2015) 0.80
The newt (Cynops pyrrhogaster) RPE65 promoter: molecular cloning, characterization and functional analysis. Transgenic Res (2014) 0.80
MITF-M, a 'melanocyte-specific' isoform, is expressed in the adult retinal pigment epithelium. Pigment Cell Melanoma Res (2012) 0.79
Microphthalmia transcription factor regulates pancreatic β-cell function. Diabetes (2013) 0.78
Identification of the minimal melanocyte-specific promoter in the melanocortin receptor 1 gene. J Exp Clin Cancer Res (2008) 0.78
Analysis of adenovirus trans-complementation-mediated gene expression controlled by melanoma-specific TETP promoter in vitro. Virol J (2010) 0.78
Keeping an eye on SOXC proteins. Dev Dyn (2014) 0.77
Overexpression of meloe gene in melanomas is controlled both by specific transcription factors and hypomethylation. PLoS One (2013) 0.77
LEF-1 Regulates Tyrosinase Gene Transcription In Vitro. PLoS One (2015) 0.76
Unusual development of light-reflecting pigment cells in intact and regenerating tail in the periodic albino mutant of Xenopus laevis. Cell Tissue Res (2010) 0.76
MicroRNA-21a-5p Functions on the Regulation of Melanogenesis by Targeting Sox5 in Mouse Skin Melanocytes. Int J Mol Sci (2016) 0.76
Dasatinib inhibits primary melanoma cell proliferation through morphology-dependent disruption of Src-ERK signaling. Oncol Lett (2012) 0.75
miR-330-5p targets tyrosinase and induces depigmentation. J Invest Dermatol (2014) 0.75
Enhanced bleaching treatment: opportunities for immune-assisted melanocyte suicide in vitiligo. Exp Dermatol (2014) 0.75
BPTF transduces MITF-driven prosurvival signals in melanoma cells. Proc Natl Acad Sci U S A (2016) 0.75
New Whitening Constituents from Taiwan-Native Pyracantha koidzumii: Structures and Tyrosinase Inhibitory Analysis in Human Epidermal Melanocytes. Int J Mol Sci (2015) 0.75
Dimerization co-factor of hepatocyte nuclear factor 1/pterin-4alpha-carbinolamine dehydratase is necessary for pigmentation in Xenopus and overexpressed in primary human melanoma lesions. Am J Pathol (2001) 0.75
Tuberous sclerosis complex inactivation disrupts melanogenesis via mTORC1 activation. J Clin Invest (2016) 0.75
In Silico Analysis of Gene Expression Network Components Underlying Pigmentation Phenotypes in the Python Identified Evolutionarily Conserved Clusters of Transcription Factor Binding Sites. Adv Bioinformatics (2016) 0.75
Inhibitory effects of ginsenosides on basic fibroblast growth factor-induced melanocyte proliferation. J Ginseng Res (2016) 0.75
Zebrafish phosvitin-derived peptide Pt5 inhibits melanogenesis via cAMP pathway. Fish Physiol Biochem (2017) 0.75
The integrated analysis of RNA-seq and microRNA-seq depicts miRNA-mRNA networks involved in Japanese flounder (Paralichthys olivaceus) albinism. PLoS One (2017) 0.75
The functional property of royal jelly 10-hydroxy-2-decenoic acid as a melanogenesis inhibitor. BMC Complement Altern Med (2017) 0.75
MITF and PU.1 inhibit adipogenesis of ovine primary preadipocytes by restraining C/EBPβ. Cell Mol Biol Lett (2017) 0.75