Published in Br J Cancer on July 01, 2000
Stat3: linking inflammation to epithelial cancer - more than a "gut" feeling? Cell Div (2010) 1.70
Reg gene family and human diseases. World J Gastroenterol (2003) 1.27
Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer. Gut (2005) 1.15
Expression profile of the REG gene family in colorectal carcinoma. J Histochem Cytochem (2011) 0.95
Regenerating proteins and their expression, regulation and signaling. Biomol Concepts (2011) 0.94
Potential prognostic, diagnostic and therapeutic markers for human gastric cancer. World J Gastroenterol (2014) 0.82
REG4 independently predicts better prognosis in non-mucinous colorectal cancer. PLoS One (2014) 0.82
Identification of tumor-associated antigens by large-scale analysis of genes expressed in human colorectal cancer. Cancer Immun (2008) 0.81
Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers. World J Gastroenterol (2012) 0.78
Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk. Oncotarget (2016) 0.77
Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma. Diagn Pathol (2016) 0.75
Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APCMin/+ Mouse Model of Intestinal Tumorigenesis. PLoS One (2016) 0.75
Expression of Reg family proteins in embryonic stem cells and its modulation by Wnt/beta-catenin signaling. Stem Cells Dev (2010) 0.75
Genetic and transcriptional analysis of human host response to healthy gut microbiota. mSystems (2016) 0.75
A genetic model for colorectal tumorigenesis. Cell (1990) 44.37
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Microsatellite instability in cancer of the proximal colon. Science (1993) 14.51
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med (1997) 12.65
Fluorouracil plus levamisole as effective adjuvant therapy after resection of stage III colon carcinoma: a final report. Ann Intern Med (1995) 3.83
Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst (1999) 3.46
Cell proliferation in carcinogenesis. Science (1990) 3.43
Inhibition of apoptosis during development of colorectal cancer. Cancer Res (1995) 2.77
A novel gene activated in regenerating islets. J Biol Chem (1988) 2.71
bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res (1995) 2.56
p53 in colorectal cancer: clinicopathological correlation and prognostic significance. Br J Cancer (1991) 1.70
Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma. Lancet (1992) 1.69
Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues. The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene. J Biol Chem (1990) 1.60
Dietary factors and risk of colon cancer. Ann Med (1994) 1.57
Pancreatic beta-cell replication and amelioration of surgical diabetes by Reg protein. Proc Natl Acad Sci U S A (1994) 1.41
Structure, chromosomal localization, and expression of mouse reg genes, reg I and reg II. A novel type of reg gene, reg II, exists in the mouse genome. J Biol Chem (1993) 1.37
A novel gene (HIP) activated in human primary liver cancer. Cancer Res (1992) 1.30
p53 nuclear overexpression: an independent predictor of survival in lymph node--positive colorectal cancer patients. J Clin Oncol (1994) 1.22
Microsatellite instability in ulcerative colitis-associated colorectal dysplasias and cancers. Cancer Res (1994) 1.20
The common molecular genetic alterations in Dukes' B and C colorectal carcinomas are not short-term prognostic indicators of survival. Int J Cancer (1994) 1.18
Reduced bile acid-induced apoptosis in "normal" colorectal mucosa: a potential biological marker for cancer risk. Cancer Res (1996) 1.17
Human REG family genes are tandemly ordered in a 95-kilobase region of chromosome 2p12. FEBS Lett (1995) 1.15
Reg gene expression is increased in rat gastric enterochromaffin-like cells following water immersion stress. Gastroenterology (1996) 1.10
Recent hypotheses for the origin of colon cancer. Cancer Res (1987) 1.08
Comparison of p53 gene mutation and protein overexpression in colorectal carcinomas. Br J Cancer (1994) 1.08
pap, reg Ialpha and reg Ibeta mRNAs are concomitantly up-regulated during human colorectal carcinogenesis. Int J Cancer (1999) 1.04
Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer. Eur J Biochem (1994) 1.02
Overexpression of p53 and long-term survival in colon carcinoma. Br J Cancer (1994) 1.01
Immunocytochemical localization of pancreatitis-associated protein in human small intestine. Dig Dis Sci (1995) 0.98
Expression of REG protein during cell growth and differentiation of two human colon carcinoma cell lines. J Histochem Cytochem (1999) 0.96
Pancreatic regeneration (reg) gene expression in a rat model of islet hyperplasia. Surgery (1996) 0.96
Expression of human regenerating gene mRNA and its product in normal and neoplastic human pancreas. Cancer (1992) 0.95
Adjuvant therapy for rectal cancer--a good first step. N Engl J Med (1997) 0.91
Pancreatic reg gene expression is inhibited during cellular differentiation. Ann Surg (1997) 0.86
A gene homologous to the reg gene is expressed in the human pancreas. FEBS Lett (1993) 0.82
Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res (1989) 15.35
Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 10.52
A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones. Nucleic Acids Res (1990) 8.52
Rapid synthesis of oligodeoxyribonucleotides. IV. Improved solid phase synthesis of oligodeoxyribonucleotides through phosphotriester intermediates. Nucleic Acids Res (1980) 7.01
Prospective evaluation of laparoscopic-assisted colectomy in an unselected group of patients. Lancet (1992) 5.40
Vertebrate pseudogenes. FEBS Lett (2000) 3.93
Isolation of cDNA clones for the human complement protein factor B, a class III major histocompatibility complex gene product. Proc Natl Acad Sci U S A (1982) 3.89
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol (1995) 3.86
Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer. Br J Surg (2010) 3.63
CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol (1994) 3.48
Isolation of cDNA clones encoding the 20K T3 glycoprotein of human T-cell receptor complex. Nature (1985) 3.34
Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase. Proc Natl Acad Sci U S A (1983) 3.33
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat Genet (2001) 3.15
Diagnosis of alpha 1-antitrypsin deficiency by enzymatic amplification of human genomic DNA and direct sequencing of polymerase chain reaction products. Nucleic Acids Res (1988) 3.00
Solid phase phosphotriester synthesis of large oligodeoxyribonucleotides on a polyamide support. Nucleic Acids Res (1980) 2.96
Total synthesis of a human leukocyte interferon gene. Nature (1981) 2.76
mRNA sequences define an unusually restricted IgG response to 2-phenyloxazolone and its early diversification. Nature (1983) 2.72
Risk of neoplasia in renal transplant patients. Lancet (1995) 2.65
EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle. Oncogene (1998) 2.65
Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal carcinoma. Gut (2000) 2.56
A 3.5 genome equivalent multi access YAC library: construction, characterisation, screening and storage. Nucleic Acids Res (1990) 2.51
Mutations in the pre-mRNA splicing factor gene PRPC8 in autosomal dominant retinitis pigmentosa (RP13). Hum Mol Genet (2001) 2.48
Observer variation in clinical diagnosis--a computer-aided assessment of its magnitude and importance in 552 patients with abdominal pain. Methods Inf Med (1973) 2.42
Production of artificial "case histories" by using a small computer. Br Med J (1971) 2.41
Compared with parenteral nutrition, enteral feeding attenuates the acute phase response and improves disease severity in acute pancreatitis. Gut (1998) 2.36
Human adenosine deaminase. cDNA and complete primary amino acid sequence. J Biol Chem (1984) 2.33
The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2. Eur J Hum Genet (2000) 2.31
Redefining the R1 resection in pancreatic cancer. Br J Surg (2006) 2.30
Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans. Nature (1984) 2.18
Prospective randomized trial of carotid endarterectomy with primary closure and patch angioplasty with saphenous vein, jugular vein, and polytetrafluoroethylene: perioperative (30-day) results. J Vasc Surg (1996) 2.14
Laparoscopic resection of colon Cancer: consensus of the European Association of Endoscopic Surgery (EAES). Surg Endosc (2004) 2.01
Primary autosomal recessive microcephaly (MCPH1) maps to chromosome 8p22-pter. Am J Hum Genet (1998) 2.00
Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis. J Clin Invest (1983) 1.95
Multicenter collaborative evaluation of a standardized serum bactericidal test as a prognostic indicator in infective endocarditis. Am J Med (1985) 1.92
beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects. Proc Natl Acad Sci U S A (1984) 1.92
The response of general surgeons to HIV in England and Wales. Ann R Coll Surg Engl (1990) 1.89
Bladder and sexual function following resection for rectal cancer in a randomized clinical trial of laparoscopic versus open technique. Br J Surg (2005) 1.89
A unifying explanation of primary generalized seizures through nonlinear brain modeling and bifurcation analysis. Cereb Cortex (2005) 1.83
Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig. Proc Natl Acad Sci U S A (1983) 1.82
Alu sequences. FEBS Lett (1997) 1.81
Non-operative management of the primary tumour in patients with incurable stage IV colorectal cancer. Br J Surg (2001) 1.74
A new technique for renal allograft biopsy. Br J Radiol (1987) 1.74
Laparoscopic omental patch repair of perforated duodenal ulcer with an automated stapler. Br J Surg (1993) 1.73
Isolation of Helicobacter pylori from feces of patients with dyspepsia in the United Kingdom. Gastroenterology (1994) 1.73
Isolation of a cDNA clone for human antithrombin III. J Biol Chem (1983) 1.69
Changes in major histocompatibility complex class II expression in monocytes and T cells of patients developing infection after surgery. Br J Surg (1993) 1.68
Construction and uses of a 'data-base' of clinical information concerning 600 patients with acute abdominal pain. Proc R Soc Med (1971) 1.67
Brachiocephalic revascularization: a comparison between carotid-subclavian artery bypass and axilloaxillary artery bypass. Surgery (1992) 1.65
The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1. J Biol Chem (1999) 1.64
Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA. Proc Natl Acad Sci U S A (1981) 1.63
Expression of survivin, a novel inhibitor of apoptosis and cell cycle regulatory protein, in pancreatic adenocarcinoma. Br J Cancer (2002) 1.62
Comparison between peripherally implanted ports and externally sited catheters for long-term venous access. Ann R Coll Surg Engl (1994) 1.62
Regulation and function of the interaction between the APC tumour suppressor protein and EB1. Oncogene (2000) 1.60
Experience with surgical implantation of catheters for continuous ambulatory peritoneal dialysis. Ann R Coll Surg Engl (1985) 1.54
Isolation and characterisation of a cDNA clone for human apolipoprotein CI and assignment of the gene to chromosome 19. Hum Genet (1985) 1.53
Anti-oxazolone hybridomas and the structure of the oxazolone idiotype. J Immunol (1983) 1.52
A multicenter phase II clinical trial using dacarbazine and continuous infusion interleukin-2 for metastatic melanoma. Clinical data and immunomonitoring. Cancer (1995) 1.52
Transforming activity of polyoma virus middle-T antigen probed by site-directed mutagenesis. Nature (1983) 1.52
Immunohistochemical detection of the anti-apoptosis protein, survivin, predicts survival after curative resection of stage II colorectal carcinomas. Ann Surg Oncol (2001) 1.48
Cost implications of alternative treatments for AIDS patients with cryptococcal meningitis. Comparison of fluconazole and amphotericin B-based therapies. J Infect (1991) 1.47
Spectrum, frequency and penetrance of OPA1 mutations in dominant optic atrophy. Hum Mol Genet (2001) 1.45
Fcgamma receptor type IIIA is associated with rheumatoid arthritis in two distinct ethnic groups. Arthritis Rheum (2000) 1.44
Molecular cloning of human adenosine deaminase gene sequences. J Biol Chem (1983) 1.44
Localization of cyclooxygenase-2 in human sporadic colorectal adenomas. Am J Pathol (2000) 1.42
Clinical, hemodynamic, and anatomic predictors of long-term outcome of lower extremity venovenous bypasses. J Vasc Surg (1991) 1.42
Patient factors influencing conversion from laparoscopically assisted to open surgery for colorectal cancer. Br J Surg (2008) 1.37
Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7. J Biol Chem (2001) 1.37
Amplification refractory mutation system for prenatal diagnosis and carrier assessment in cystic fibrosis. Lancet (1990) 1.36
Identification of a point mutation in the adenosine deaminase gene responsible for immunodeficiency. J Clin Invest (1985) 1.35
Adhesions and incisional hernias following laparoscopic versus open surgery for colorectal cancer in the CLASICC trial. Br J Surg (2010) 1.35
Joining of synthetic ribotrinucleotides with defined sequences catalyzed by T4 RNA ligase. Eur J Biochem (1977) 1.34
Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures. An analysis of the second hit. J Bone Joint Surg Br (1999) 1.33
Hypophosphataemia: A complication of "innocuous dextrose-saline". Lancet (1976) 1.31
Prospective randomized trial of carotid endarterectomy with primary closure and patch angioplasty with saphenous vein, jugular vein, and polytetrafluoroethylene: long-term follow-up. J Vasc Surg (1998) 1.30
Randomized clinical trial of Ligasure versus conventional diathermy for day-case haemorrhoidectomy. Br J Surg (2002) 1.29
Cholecystectomy is safer without drainage: the results of a prospective, randomized clinical trial. Surgery (1991) 1.29
Isolation of cDNA clones using yeast artificial chromosome probes. Nucleic Acids Res (1990) 1.28
The lateral paramedian incision--experience with 850 cases. Br J Surg (1982) 1.27
Mutations around the NG59 lesion indicate an active association of polyoma virus middle-T antigen with pp60c-src is required for cell transformation. EMBO J (1986) 1.27
Helicobacter pylori and gastric mucosal cytokines: evidence that CagA-positive strains are more virulent. Lab Invest (1995) 1.26
Unified neurophysical model of EEG spectra and evoked potentials. Biol Cybern (2002) 1.25
Vertical abdominal incisions--a choice? Br J Surg (1980) 1.24
Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridisation. Br J Cancer (2003) 1.23
Direct haplotype determination by double ARMS: specificity, sensitivity and genetic applications. Nucleic Acids Res (1991) 1.22
Cyclooxygenase 2 is up-regulated and localized to macrophages in the intestine of Min mice. Br J Cancer (1999) 1.22
Identification of mutations in the connexin 26 gene that cause autosomal recessive nonsyndromic hearing loss. Hum Mutat (1998) 1.21
Lymphocyte transformation in the mesenteric lymph nodes of patients with Crohn's disease. Gut (1973) 1.21
Tumour-induced apoptosis in human mesothelial cells: a mechanism of peritoneal invasion by Fas Ligand/Fas interaction. Br J Cancer (2004) 1.20
A quantitative model of sleep-wake dynamics based on the physiology of the brainstem ascending arousal system. J Biol Rhythms (2007) 1.19
Joining of 3'-modified oligonucleotides by T4 RNA ligase. Synthesis of a heptadecanucleotide corresponding to the bases 61--77 from Escherichia coli tRNAfMet. Biochemistry (1978) 1.19
Helicobacter pylori-stimulated EGF receptor transactivation requires metalloprotease cleavage of HB-EGF. Biochem Biophys Res Commun (2002) 1.19