Postmenopausal estrogen therapy and depressive symptoms in older women.

PubWeight™: 0.96‹?› | Rank: Top 15%

🔗 View Article (PMC 1495584)

Published in J Gen Intern Med on August 01, 2000

Authors

M A Whooley1, D Grady, J A Cauley

Author Affiliations

1: Section of General Internal Medicine, San Francisco Department of Veterans Affairs Medical Center, Departments of Medicine and Epidemiology and Biostatistics, University of California, San Francisco, California, USA. whooley@itsa.ucsf.edu

Associated clinical trials:

Premenstrual Syndrome Etiology Pilot Study (PMSe-Pilot) | NCT03862469

Articles citing this

Estrogen treatment impairs cognitive performance after psychosocial stress and monoamine depletion in postmenopausal women. Menopause (2010) 0.89

Treatment with hormone therapy and calcitriol did not affect depression in older postmenopausal women: no interaction with estrogen and vitamin D receptor genotype polymorphisms. Menopause (2012) 0.88

Postmenopausal hormone use impact on emotion processing circuitry. Behav Brain Res (2011) 0.84

Neurobiological Underpinnings of the Estrogen - Mood Relationship. Curr Psychiatry Rev (2012) 0.83

Lifetime hormonal factors may predict late-life depression in women. Int Psychogeriatr (2008) 0.83

Effects of hormone therapy on cognition and mood. Fertil Steril (2014) 0.81

Treatment of depression associated with the menstrual cycle: premenstrual dysphoria, postpartum depression, and the perimenopause. Dialogues Clin Neurosci (2002) 0.79

Changes in elderly women's health-related quality of life following discontinuation of hormone replacement therapy. BMC Womens Health (2005) 0.79

A prospective study of hormone therapy and depression in community-dwelling elderly women: the Three City Study. J Clin Psychiatry (2010) 0.78

Women's health. An evolving mosaic. J Gen Intern Med (2000) 0.78

Interventions that improve the quality of depression care: where do we go from here? J Gen Intern Med (2000) 0.75

GABA+ levels in postmenopausal women with mild-to-moderate depression: A preliminary study. Medicine (Baltimore) (2016) 0.75

Articles cited by this

Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA (1998) 24.54

The functioning and well-being of depressed patients. Results from the Medical Outcomes Study. JAMA (1989) 12.07

Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol (1978) 11.61

Geriatric Depression Scale. Psychopharmacol Bull (1988) 6.27

Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. JAMA (1990) 6.25

Effects of raloxifene on bone mineral density, serum cholesterol concentrations, and uterine endometrium in postmenopausal women. N Engl J Med (1997) 6.15

A molecular and cellular theory of depression. Arch Gen Psychiatry (1997) 6.10

Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire. Arthritis Rheum (1983) 5.96

Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial. The Writing Group for the PEPI Trial. JAMA (1995) 5.91

Depression, disability days, and days lost from work in a prospective epidemiologic survey. JAMA (1990) 4.70

Health-related quality of life in primary care patients with mental disorders. Results from the PRIME-MD 1000 Study. JAMA (1995) 4.40

Service utilization and social morbidity associated with depressive symptoms in the community. JAMA (1992) 3.26

Prior to use of estrogen replacement therapy, are users healthier than nonusers? Am J Epidemiol (1996) 3.18

Diagnosis and treatment of depression in late life. Consensus statement update. JAMA (1997) 3.14

Postmenopausal estrogen and prevention bias. Ann Intern Med (1991) 2.31

Hormone replacement therapy and endometrial cancer risk: a meta-analysis. Obstet Gynecol (1995) 2.30

Association between depressive symptoms and mortality in older women. Study of Osteoporotic Fractures Research Group. Arch Intern Med (1998) 2.10

Oestrogen therapy and the menopausal syndrome. Clin Obstet Gynaecol (1977) 1.77

Evidence of a healthy estrogen user survivor effect. Epidemiology (1995) 1.72

Prevalence and determinants of estrogen replacement therapy in elderly women. Am J Obstet Gynecol (1990) 1.49

Estrogen control of central neurotransmission: effect on mood, mental state, and memory. Cell Mol Neurobiol (1996) 1.42

Estrogen-serotonin interactions: implications for affective regulation. Biol Psychiatry (1998) 1.40

Effect of oestrogen and testosterone implants on psychological disorders in the climacteric. Lancet (1987) 1.33

Depression--medical utilization and somatization. West J Med (1986) 1.31

Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge? Biol Psychiatry (1998) 1.31

Psychiatric disorder and functional somatic symptoms as predictors of health care use. Psychiatr Med (1992) 1.26

The impact of different doses of estrogen and progestin on mood and sexual behavior in postmenopausal women. J Clin Endocrinol Metab (1991) 1.25

Performance of case-finding tools for depression in the nursing home: influence of clinical and functional characteristics and selection of optimal threshold scores. J Am Geriatr Soc (1994) 1.22

A meta-analysis of the effect of hormone replacement therapy upon depressed mood. Psychoneuroendocrinology (1997) 1.13

Estrogen improves psychological function in asymptomatic postmenopausal women. Obstet Gynecol (1991) 1.07

Sex steroids and affect in the surgical menopause: a double-blind, cross-over study. Psychoneuroendocrinology (1985) 1.06

Selective estrogen receptor modulators and postmenopausal women's health. J Womens Health (1997) 1.04

Selective estrogen receptor modulators: an alternative to hormone replacement therapy. Proc Soc Exp Biol Med (1998) 1.01

Estrogen augments serotonergic activity in postmenopausal women. Biol Psychiatry (1995) 0.98

Effect of oestrogen on the sleep, mood, and anxiety of menopausal women. Br Med J (1977) 0.98

Estrogen therapy for severe persistent depressions in women. Arch Gen Psychiatry (1979) 0.97

Affective changes with estrogen and androgen replacement therapy in surgically menopausal women. J Affect Disord (1988) 0.96

Steroid hormones: humoral signals which alter brain cell properties and functions. Recent Prog Horm Res (1982) 0.95

Is oestrogen therapy effective in the treatment of menopausal depression? J R Coll Gen Pract (1981) 0.94

The female brain hypoestrogenic continuum from the premenstrual syndrome to menopause. A hypothesis and review of supporting data. J Reprod Med (1996) 0.93

Quality of life during sequential hormone replacement therapy -- a placebo-controlled study. Int J Fertil Menopausal Stud (1995) 0.87

Double-blind, placebo-controlled, hormonal, syndromal and EEG mapping studies with transdermal oestradiol therapy in menopausal depression. Psychopharmacology (Berl) (1995) 0.85

Basic psychopharmacology of antidepressants, part 2: Estrogen as an adjunct to antidepressant treatment. J Clin Psychiatry (1998) 0.83

Hormonal, syndromal and EEG mapping studies in menopausal syndrome patients with and without depression as compared with controls. Maturitas (1996) 0.83

Hormonal and non-hormonal interventions for menopausal symptoms. Maturitas (1996) 0.81

Lack of efficacy of estrogen supplementation to imipramine in resistant female depressives. Biol Psychiatry (1985) 0.79

In search of optimal long-term female hormone replacement: the potential of selective estrogen receptor modulators. Horm Res (1997) 0.79

Platelet serotonin content and plasma tryptophan in peri- and postmenopausal women: variations with plasma oestrogen levels and depressive symptoms. Eur J Clin Invest (1988) 0.79

Estrogen use and depressive symptoms in postmenopausal women. Obstet Gynecol (1992) 0.78

Addition of estrogen to imipramine in female-resistant depressives. Psychopharmacol Bull (1985) 0.78

Hormone therapy and affect. Maturitas (1979) 0.78

Changes in the pituitary and hypothalamic content of methionine-enkephalin during the estrous cycle of rats. Life Sci (1979) 0.78

The role of oestrogen replacement in the climacteric syndrome. Psychol Med (1977) 0.78

Effect of exogenous oestrogens on minor psychiatric symptoms in postmenopausal women. S Afr Med J (1973) 0.77

Estrogen in the treatment of depression: neuropharmacological mechanisms. Biol Psychiatry (1983) 0.77

Antidepressant effects of estrogen. J Clin Psychiatry (1985) 0.76

Effects of estrogen therapy on plasma MAO activity and EEG driving responses of depressed women. Am J Psychiatry (1972) 0.76

Articles by these authors

Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA (1998) 24.54

Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet (1996) 13.20

Left ventricular pseudoaneurysm. J Am Coll Cardiol (1998) 8.81

The effect of raloxifene on risk of breast cancer in postmenopausal women: results from the MORE randomized trial. Multiple Outcomes of Raloxifene Evaluation. JAMA (1999) 7.30

Efficacy of screening mammography. A meta-analysis. JAMA (1995) 6.94

Incidence of and treatment for ductal carcinoma in situ of the breast. JAMA (1996) 6.53

Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. JAMA (1990) 6.25

Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst (2003) 6.20

Effect of age, breast density, and family history on the sensitivity of first screening mammography. JAMA (1996) 4.89

Health risks and benefits from calcium and vitamin D supplementation: Women's Health Initiative clinical trial and cohort study. Osteoporos Int (2012) 4.09

Urinary incontinence: does it increase risk for falls and fractures? Study of Osteoporotic Fractures Research Group. J Am Geriatr Soc (2000) 4.05

Older women with diabetes have an increased risk of fracture: a prospective study. J Clin Endocrinol Metab (2001) 4.03

Continuing screening mammography in women aged 70 to 79 years: impact on life expectancy and cost-effectiveness. JAMA (1999) 3.82

Should we be measuring blood cholesterol levels in young adults? JAMA (1993) 3.57

Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients with unstable angina. A meta-analysis. JAMA (1996) 3.54

Changes in the pharmacokinetics of ciprofloxacin and fecal flora during administration of a 7-day course to human volunteers. Antimicrob Agents Chemother (1984) 3.35

Endovaginal ultrasound to exclude endometrial cancer and other endometrial abnormalities. JAMA (1998) 3.32

Patterns of cognitive decline in presymptomatic Alzheimer disease: a prospective community study. Arch Gen Psychiatry (2001) 3.32

Prevalence of urinary incontinence and associated risk factors in postmenopausal women. Heart & Estrogen/Progestin Replacement Study (HERS) Research Group. Obstet Gynecol (1999) 3.19

Variability and accuracy in mammographic interpretation using the American College of Radiology Breast Imaging Reporting and Data System. J Natl Cancer Inst (1998) 3.08

Positive predictive value of screening mammography by age and family history of breast cancer. JAMA (1993) 2.95

Hysterectomy and urinary incontinence: a systematic review. Lancet (2000) 2.89

Contribution of vertebral deformities to chronic back pain and disability. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res (1992) 2.82

Cognitive decline in women in relation to non-protein-bound oestradiol concentrations. Lancet (2000) 2.82

Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med (2000) 2.81

Prevalent vertebral deformities predict mortality and hospitalization in older women with low bone mass. Fracture Intervention Trial Research Group. J Am Geriatr Soc (2000) 2.80

Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented. Neurology (2000) 2.79

Antibiotics in chronic obstructive pulmonary disease exacerbations. A meta-analysis. JAMA (1995) 2.69

Factors associated with appendicular bone mass in older women. The Study of Osteoporotic Fractures Research Group. Ann Intern Med (1993) 2.65

Reproducibility and validity of an epidemiologic questionnaire to assess past year physical activity in adolescents. Am J Epidemiol (1995) 2.65

A randomized walking trial in postmenopausal women: effects on physical activity and health 10 years later. Arch Intern Med (1998) 2.62

Broadband ultrasound attenuation predicts fractures strongly and independently of densitometry in older women. A prospective study. Study of Osteoporotic Fractures Research Group. Arch Intern Med (1997) 2.50

Likelihood ratios for modern screening mammography. Risk of breast cancer based on age and mammographic interpretation. JAMA (1996) 2.44

Interpretation and use of FRAX in clinical practice. Osteoporos Int (2011) 2.43

Growth hormone replacement in healthy older men improves body composition but not functional ability. Ann Intern Med (1996) 2.36

The accuracy of self-report of fractures in elderly women: evidence from a prospective study. Am J Epidemiol (1992) 2.33

Physical activity and osteoporotic fracture risk in older women. Study of Osteoporotic Fractures Research Group. Ann Intern Med (1998) 2.22

Meta-analysis of exercise testing to detect coronary artery disease in women. Am J Cardiol (1999) 2.20

Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies. Br J Cancer (2011) 2.20

Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study. J Bone Miner Res (2001) 2.16

Estrogen therapy in postmenopausal women: effects on cognitive function and dementia. JAMA (1998) 2.14

The association of endogenous hormone concentrations and bone mineral density measures in pre- and perimenopausal women of four ethnic groups: SWAN. Osteoporos Int (2003) 2.13

Postmenopausal hormone therapy and risk of stroke: The Heart and Estrogen-progestin Replacement Study (HERS). Circulation (2001) 2.12

Urinary incontinence in older women: who is at risk? Study of Osteoporotic Fractures Research Group. Obstet Gynecol (1996) 2.09

The epidemiology of low back pain in an adolescent population. Am J Public Health (1992) 2.07

Decreased ankle/arm blood pressure index and mortality in elderly women. JAMA (1993) 2.06

Postmenopausal bone density and milk consumption in childhood and adolescence. Am J Clin Nutr (1985) 2.00

Low fractional calcium absorption increases the risk for hip fracture in women with low calcium intake. Study of Osteoporotic Fractures Research Group. Ann Intern Med (2000) 1.94

The association between sleep duration and obesity in older adults. Int J Obes (Lond) (2008) 1.89

Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group. Osteoporos Int (1994) 1.88

Cognitive function in postmenopausal women treated with raloxifene. N Engl J Med (2001) 1.87

High body fatness, but not low fat-free mass, predicts disability in older men and women: the Cardiovascular Health Study. Am J Clin Nutr (1998) 1.82

Measurement of fat mass using DEXA: a validation study in elderly adults. J Appl Physiol (1985) (2000) 1.81

Hormone replacement therapy, heart disease, and other considerations. Annu Rev Public Health (1998) 1.78

Depression, falls, and risk of fracture in older women. Study of Osteoporotic Fractures Research Group. Arch Intern Med (1999) 1.75

The epidemiology of physical activity in children, college students, middle-aged men, menopausal females and monkeys. J Chronic Dis (1982) 1.72

Advanced glycation end product level, diabetes, and accelerated cognitive aging. Neurology (2011) 1.69

Molecular epidemiology of vitamin D receptor gene variants. Epidemiol Rev (2000) 1.68

Serum estrogen levels, cognitive performance, and risk of cognitive decline in older community women. J Am Geriatr Soc (1998) 1.66

Correlates of impaired function in older women. J Am Geriatr Soc (1994) 1.65

Hormone therapy and in-hospital survival after myocardial infarction in postmenopausal women. Circulation (2001) 1.61

Antibiotics at the time of induced abortion: the case for universal prophylaxis based on a meta-analysis. Obstet Gynecol (1996) 1.59

High blood pressure and bone-mineral loss in elderly white women: a prospective study. Study of Osteoporotic Fractures Research Group. Lancet (1999) 1.57

Renal insufficiency and cardiovascular events in postmenopausal women with coronary heart disease. J Am Coll Cardiol (2001) 1.56

Hip structural geometry and incidence of hip fracture in postmenopausal women: what does it add to conventional bone mineral density? Osteoporos Int (2009) 1.56

Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former Multiple Risk Factor Intervention Trial participants. Am J Epidemiol (1997) 1.52

The assessment of historical physical activity and its relation to adult bone parameters. Am J Epidemiol (1988) 1.51

Bone mineral density and blood flow to the lower extremities: the study of osteoporotic fractures. J Bone Miner Res (1997) 1.45

The lumpy breast. West J Med (1988) 1.43

Association of estrogen replacement therapy with the risk of osteoarthritis of the hip in elderly white women. Study of Osteoporotic Fractures Research Group. Arch Intern Med (1996) 1.42

Therapeutic controversy: Estrogen replacement in menopause. J Clin Endocrinol Metab (1996) 1.41

Associations between low levels of serum estradiol, bone density, and fractures among elderly women: the study of osteoporotic fractures. J Clin Endocrinol Metab (1998) 1.41

25-Hydroxyvitamin D levels and cognitive performance and decline in elderly men. Neurology (2009) 1.40

Back problems among postmenopausal women taking estrogen replacement therapy: the study of osteoporotic fractures. Spine (Phila Pa 1976) (2001) 1.40

Benefit of mammography screening in women ages 40-49 years: current evidence from randomized controlled trials. Cancer (1995) 1.39

Carpal tunnel syndrome. West J Med (1988) 1.38

Correlates of bone mineral density in men of African ancestry: the Tobago bone health study. Osteoporos Int (2007) 1.36

Does a fixed physician reminder system improve the care of patients with coronary artery disease? A randomized controlled trial. West J Med (2001) 1.35

A randomized exercise trial in older women: increased activity over two years and the factors associated with compliance. Med Sci Sports Exerc (1986) 1.35

Body size and hip fracture risk in older women: a prospective study. Study of Osteoporotic Fractures Research Group. Am J Med (1997) 1.34

Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients. Anesth Analg (2005) 1.29

The association between osteopenia and periodontal attachment loss in older women. J Periodontol (1999) 1.28

The waning effect of postmenopausal estrogen therapy on osteoporosis. N Engl J Med (1993) 1.27

Genetic markers for ancestry are correlated with body composition traits in older African Americans. Osteoporos Int (2007) 1.27

Antibiotics in acute bronchitis: a meta-analysis. Am J Med (1999) 1.24

Effect of a lifestyle intervention on bone mineral density in premenopausal women: a randomized trial. Am J Clin Nutr (1999) 1.22

Higher 1,25-dihydroxyvitamin D3 concentrations associated with lower fall rates in older community-dwelling women. Osteoporos Int (2006) 1.22

The epidemiology of leisure physical activity in an adolescent population. Med Sci Sports Exerc (1993) 1.21

The association of bone mineral density measures with incident cardiovascular disease in older adults. Osteoporos Int (2007) 1.19

Endogenous hormones and bone turnover markers in pre- and perimenopausal women: SWAN. Osteoporos Int (2003) 1.19

Periodontal effects associated with the use of smokeless tobacco. J Periodontol (1990) 1.17

Allelic variants of aromatase and the androgen and estrogen receptors: toward a multigenic model of prostate cancer risk. Clin Cancer Res (2001) 1.15

Lumbar olisthesis and lower back symptoms in elderly white women. The Study of Osteoporotic Fractures. Spine (Phila Pa 1976) (1998) 1.14

Factors associated with calcium absorption efficiency in pre- and perimenopausal women. Am J Clin Nutr (2000) 1.13

Association between low bone density and stroke in elderly women. The study of osteoporotic fractures. Stroke (1993) 1.13

Predictors of physical activity in community-dwelling elderly white women. J Gen Intern Med (2001) 1.12

Volumetric and areal bone mineral density measures are associated with cardiovascular disease in older men and women: the health, aging, and body composition study. Calcif Tissue Int (2006) 1.12

Cigarette smoking and serum sex hormones in men. Am J Epidemiol (1988) 1.11

Comparison of risk factors for ductal carcinoma in situ and invasive breast cancer. J Natl Cancer Inst (1997) 1.11