Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 10961873)

Published in Blood on September 01, 2000

Authors

D Bryder1, S E Jacobsen

Author Affiliations

1: Stem Cell Laboratory, Institute of Laboratory Medicine, University Hospital of Lund, Sweden. David.Bryder@molmed.lu.se

Articles citing this

Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest (2003) 2.37

Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J Exp Med (2000) 1.78

Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation. J Exp Med (2001) 1.22

Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. Exp Hematol (2007) 1.13

Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis. BMC Immunol (2006) 1.01

A novel assay to trace proliferation history in vivo reveals that enhanced divisional kinetics accompany loss of hematopoietic stem cell self-renewal. PLoS One (2008) 0.96

Hematopoietic stem cells: transcriptional regulation, ex vivo expansion and clinical application. Curr Mol Med (2012) 0.87

Expansion on stromal cells preserves the undifferentiated state of human hematopoietic stem cells despite compromised reconstitution ability. PLoS One (2013) 0.84

In vitro culture during retroviral transduction improves thymic repopulation and output after total body irradiation and autologous peripheral blood progenitor cell transplantation in rhesus macaques. Stem Cells (2006) 0.83

Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion. Stem Cells Int (2011) 0.83

Increasing hematopoietic stem cell yield to develop mice with human immune systems. Biomed Res Int (2013) 0.78

Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells from hematopoietic stem cells. J Immune Based Ther Vaccines (2010) 0.78

In vitro production of functional immune cells derived from human hematopoietic stem cells. EXCLI J (2015) 0.76

Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance. Front Immunol (2016) 0.75

Articles by these authors

Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation. Science (2001) 5.50

Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity. Immunity (2001) 5.14

Characterization and regulation of RB6-8C5 antigen expression on murine bone marrow cells. J Immunol (1991) 5.02

Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci. Plant J (1996) 4.24

The late flowering phenotype of fwa mutants is caused by gain-of-function epigenetic alleles of a homeodomain gene. Mol Cell (2000) 4.16

The CLAVATA and SHOOT MERISTEMLESS loci competitively regulate meristem activity in Arabidopsis. Development (1996) 3.22

Conserved plant genes with similarity to mammalian de novo DNA methyltransferases. Proc Natl Acad Sci U S A (2000) 2.72

c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities. Blood (1998) 2.53

Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level. Blood (2000) 1.88

Genetic analyses of DNA methyltransferases in Arabidopsis thaliana. Cold Spring Harb Symp Quant Biol (2006) 1.78

Site specificity of the Arabidopsis METI DNA methyltransferase demonstrated through hypermethylation of the superman locus. Plant Mol Biol (2001) 1.44

Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells. Blood (2001) 1.28

Self-renewal of multipotent long-term repopulating hematopoietic stem cells is negatively regulated by Fas and tumor necrosis factor receptor activation. J Exp Med (2001) 1.22

Regulation of SUP expression identifies multiple regulators involved in arabidopsis floral meristem development. Plant Cell (2000) 1.22

CmC(A/T)GG DNA methylation in mature B cell lymphoma gene silencing. Proc Natl Acad Sci U S A (2001) 1.19

Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells. Blood (1996) 1.05

Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells. Blood (2000) 1.03

Distinct requirements for optimal growth and In vitro expansion of human CD34(+)CD38(-) bone marrow long-term culture-initiating cells (LTC-IC), extended LTC-IC, and murine in vivo long-term reconstituting stem cells. Blood (1999) 1.02

The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta. J Immunol (1996) 1.01

Tumor necrosis factor (TNF)-alpha directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptors. Blood (1995) 1.00

The FLT3 ligand is a direct and potent stimulator of the growth of primitive and committed human CD34+ bone marrow progenitor cells in vitro. Blood (1996) 0.98

Ability of early acting cytokines to directly promote survival and suppress apoptosis of human primitive CD34+CD38- bone marrow cells with multilineage potential at the single-cell level: key role of thrombopoietin. Blood (1997) 0.96

Stimulation of granulopoiesis by transforming growth factor beta: synergy with granulocyte/macrophage-colony-stimulating factor. Proc Natl Acad Sci U S A (1991) 0.96

Cloning of human early B-cell factor and identification of target genes suggest a conserved role in B-cell development in man and mouse. Blood (2000) 0.94

Transforming growth factor beta (TGF-beta), a potent inhibitor of erythropoiesis: neutralizing TGF-beta antibodies show erythropoietin as a potent stimulator of murine burst-forming unit erythroid colony formation in the absence of a burst-promoting activity. Blood (1995) 0.94

Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3. Blood (1996) 0.94

Novel role of interleukin 7 in myelopoiesis: stimulation of primitive murine hematopoietic progenitor cells. J Exp Med (1993) 0.94

Lymphoid-restricted development from multipotent candidate murine stem cells: distinct and complimentary functions of the c-kit and flt3-ligands. Blood (1999) 0.93

Role of the 75-kDa tumor necrosis factor receptor: inhibition of early hematopoiesis. Proc Natl Acad Sci U S A (1994) 0.92

Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors. Blood (1994) 0.91

Distinct and overlapping direct effects of macrophage inflammatory protein-1 alpha and transforming growth factor beta on hematopoietic progenitor/stem cell growth. Blood (1994) 0.90

Involvement of the retinoblastoma protein in monocytic and neutrophilic lineage commitment of human bone marrow progenitor cells. Blood (1999) 0.88

In vivo and in vitro effects of TGF-beta 1 on normal and neoplastic haemopoiesis. Ciba Found Symp (1991) 0.88

Tumor necrosis factor-alpha (TNF-alpha) potently enhances in vitro macrophage production from primitive murine hematopoietic progenitor cells in combination with stem cell factor and interleukin-7: novel stimulatory role of p55 TNF receptors. Blood (1994) 0.87

IL-12 directly enhances in vitro murine erythropoiesis in combination with IL-4 and stem cell factor. J Immunol (1995) 0.87

Hematopoietic growth factors and glucocorticoids synergize to mimic the effects of IL-1 on granulocyte differentiation and IL-1 receptor induction on bone marrow cells in vivo. Exp Hematol (1993) 0.87

All-trans- and 9-cis-retinoic acid inhibit growth of normal human and murine B cell precursors. J Immunol (1995) 0.86

Tumor necrosis factor-alpha inhibits stem cell factor-induced proliferation of human bone marrow progenitor cells in vitro. Role of p55 and p75 tumor necrosis factor receptors. J Clin Invest (1994) 0.85

Thrombopoietin, but not erythropoietin promotes viability and inhibits apoptosis of multipotent murine hematopoietic progenitor cells in vitro. Blood (1996) 0.85

Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+ CD38-) human bone marrow progenitor cells: distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-beta and TNF-alpha. J Immunol (1997) 0.85

All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells. Blood (1994) 0.84

Lentivirus gene transfer in murine hematopoietic progenitor cells is compromised by a delay in proviral integration and results in transduction mosaicism and heterogeneous gene expression in progeny cells. J Virol (2000) 0.84

Efficient adenoviral vector transduction of human hematopoietic SCID-repopulating and long-term culture-initiating cells. Hum Gene Ther (2000) 0.83

Interleukin-13 in combination with CD40 ligand potently inhibits apoptosis in human B lymphocytes: upregulation of Bcl-xL and Mcl-1. Blood (1997) 0.82

Complement C3b receptors on erythrocytes in patients with juvenile rheumatoid arthritis. Arthritis Rheum (1987) 0.82

Transforming growth factor-beta: a bidirectional regulator of hematopoietic cell growth. Int J Cell Cloning (1992) 0.81

Functional differences between CD38- and DR- subfractions of CD34+ bone marrow cells. Blood (1994) 0.81

The RAR-RXR as well as the RXR-RXR pathway is involved in signaling growth inhibition of human CD34+ erythroid progenitor cells. Blood (1996) 0.81

Transforming growth factor-beta1 abrogates Fas-induced growth suppression and apoptosis of murine bone marrow progenitor cells. Blood (1997) 0.81

Transforming growth factor-beta potently inhibits the viability-promoting activity of stem cell factor and other cytokines and induces apoptosis of primitive murine hematopoietic progenitor cells. Blood (1995) 0.81

Mobilization of long-term reconstituting hematopoietic stem cells in mice by recombinant human interleukin 7. J Exp Med (1995) 0.81

TNF-alpha bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro. J Immunol (1996) 0.81

Arabidopsis research 2001. Plant Cell (2001) 0.80

Transfusion problems in patients with Glanzmann's thrombasthenia. Eur J Haematol (1992) 0.80

Normal distribution of complement C3b receptor (CR1) numbers on erythrocytes in blood donors: low levels are associated with HLA-B27. Complement (1986) 0.80

Transforming growth factor beta and interleukin-1: a paradigm for opposing regulation of haemopoiesis. Baillieres Clin Haematol (1992) 0.79

Acute abdomen in rheumatoid arthritis due to mesenteric arteritis. A case report and review. Dan Med Bull (1985) 0.79

Direct synergistic effects of IL-4 and IL-11 on proliferation of primitive hematopoietic progenitor cells. Exp Hematol (1995) 0.79

In vivo effect of interleukin-1 alpha on hematopoiesis: role of colony-stimulating factor receptor modulation. Blood (1992) 0.79

Inhibition of stem cell factor-induced proliferation of primitive murine hematopoietic progenitor cells signaled through the 75-kilodalton tumor necrosis factor receptor. Regulation of c-kit and p53 expression. J Immunol (1995) 0.78

Cushing's disease presenting with severe osteoporosis. Acta Endocrinol (Copenh) (1986) 0.78

Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5. J Immunol (1997) 0.78

Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro. Blood (1994) 0.77

Hematopoietic growth factors upregulate the p65 type II interleukin-1 receptor on bone marrow progenitor cells in vitro. Blood (1992) 0.77

Role of transforming growth factor-beta 1 in regulation of hematopoiesis. Ann N Y Acad Sci (1991) 0.77

Direct synergistic effects of interleukin-7 on in vitro myelopoiesis of human CD34+ bone marrow progenitors. Blood (1994) 0.76

IL-7 stimulates CSF-induced proliferation of murine bone marrow macrophages and Mac-1+ myeloid progenitors in vitro. J Immunol (1994) 0.76

Increased granulopoiesis after sequential administration of transforming growth factor-beta 1 and granulocyte-macrophage colony-stimulating factor. Exp Hematol (1993) 0.76

[Intraoperative autotransfusion]. Ugeskr Laeger (1994) 0.75

Bidirectional effect of interleukin-10 on early murine B-cell development: stimulation of flt3-ligand plus interleukin-7-dependent generation of CD19(-) ProB cells from uncommitted bone marrow progenitor cells and growth inhibition of CD19(+) ProB cells. Blood (1997) 0.75

Failure to induce immune tolerance in a hemophilia A patient with high titre titre VIII:C inhibitor. Thromb Res (1989) 0.75

Megakaryocytopoiesis in vitro: from the stem cells' perspective. Stem Cells (1996) 0.75

Performance of hepatitis C virus (HCV) antibody test systems in relation to HCV-RNA detection in the diagnosis of HCV infection. Dan Med Bull (1998) 0.75

[Blood transfusion and risk of surgical infection]. Ugeskr Laeger (1993) 0.75

Identification of patients when taking blood. BMJ (1991) 0.75

[Cushing's syndrome in children and adolescents]. Ugeskr Laeger (1985) 0.75