S M MacLeod

Author PubWeight™ 65.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The McMaster M.D. program: a case study of renewal in medical education. Acad Med 1989 2.63
2 Pharmacokinetics and adverse effects of amphotericin B in infants and children. J Pediatr 1988 2.62
3 Evidence-based rationing: Dutch pragmatism or government insensitivity? CMAJ 1998 2.47
4 Developing a Canadian prescribing practices network. Network Development Committee of the Canadian Prescribing Practices Network Project. CMAJ 1996 1.64
5 Diazepam actions and plasma concentrations following ethanol ingestion. Eur J Clin Pharmacol 1977 1.33
6 Determinants of recall and recall bias in studying drug and chemical exposure in pregnancy. Teratology 1989 1.23
7 Ranitidine kinetics and dynamics. I. Oral dose studies. Clin Pharmacol Ther 1981 1.20
8 Corticosteroid treatment of laryngotracheitis v spasmodic croup in children. Am J Dis Child 1983 1.15
9 Paediatric clinical pharmacology and the health of the world's children. Dev Pharmacol Ther 1990 1.13
10 Measurement of amphotericin B in serum or plasma by high-performance liquid chromatography. J Chromatogr 1983 1.10
11 Influence of age and previous use of diazepam dosage required for endoscopy. Can Med Assoc J 1978 1.09
12 Impact of antibiotic administrative restrictions on trends in antibiotic resistance. Can J Public Health 2006 1.05
13 Age- and gender-related differences in diazepam pharmacokinetics. J Clin Pharmacol 1979 1.04
14 Bendectin: the wrong way to regulate drug availability. Can Med Assoc J 1983 1.04
15 Ceftazidime disposition in acute and stable cystic fibrosis. Clin Pharmacol Ther 1984 1.03
16 Chlordiazepoxide and oxazepam disposition in cirrhosis. Clin Pharmacol Ther 1979 1.00
17 Acute and chronic drug abuse emergencies in Metropolitan Toronto. Int J Addict 1981 1.00
18 Hepatic microsomal drug oxidation and electron transport in newborn infants. J Pediatr 1974 0.96
19 Cloxacillin absorption and disposition in cystic fibrosis. J Pediatr 1984 0.96
20 Intravenous paraldehyde for seizure control in newborn infants. Neurology 1986 0.96
21 Sequestration of fentanyl by the cardiopulmonary bypass (CPBP). Eur J Clin Pharmacol 1984 0.94
22 High-pressure liquid chromatographic analysis of ceftazidime in serum and urine. Antimicrob Agents Chemother 1983 0.94
23 The role of research evidence in pharmaceutical policy making: evidence when necessary but not necessarily evidence. J Eval Clin Pract 1999 0.94
24 Pharmacoepidemiology: a health imperative. J Clin Epidemiol 1991 0.93
25 Temporal variation in the disposition of theophylline and its metabolites. Clin Pharmacol Ther 1985 0.91
26 The dissociation between aminoglycoside serum concentrations and nephrotoxicity. Life Sci 1988 0.91
27 Cystic fibrosis: enhanced theophylline metabolism may be linked to the disease. Clin Pharmacol Ther 1988 0.91
28 High-pressure liquid chromatographic assays for ticarcillin in serum and urine. J Pharm Sci 1982 0.90
29 Adverse biochemical and clinical consequences of furosemide administration. Can Med Assoc J 1978 0.89
30 The influence of hypothermia on the disposition of fentanyl--human and animal studies. Eur J Clin Pharmacol 1987 0.89
31 Pharmacodynamic and pharmacokinetic drug interactions with coumarin anticoagulants. Drugs 1976 0.89
32 Fentanyl pharmacokinetics and hemodynamic effects in preterm infants during ligation of patent ductus arteriosus. Anesth Analg 1985 0.88
33 Clinical pharmacokinetics of chlordiazepoxide. Clin Pharmacokinet 1978 0.88
34 Development of hepatic microsomal drug-oxidizing enzymes in immature male and female rats. J Pharmacol Exp Ther 1972 0.88
35 Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. Pediatrics 1987 0.87
36 Analysis of ranitidine in serum by high performance liquid chromatography. Ther Drug Monit 1980 0.85
37 Effects of indomethacin on digoxin pharmacokinetics in preterm infants. Pediatr Pharmacol (New York) 1984 0.84
38 Monitoring and avoiding drug and chemical teratogenicity. CMAJ 1986 0.84
39 Assessment of glomerular filtration rate and effective renal plasma flow in cystic fibrosis. J Pediatr 1985 0.83
40 Absorption of oral and intramuscular chlordiazepoxide. Eur J Clin Pharmacol 1978 0.82
41 Propranolol-associated confused states during alcohol withdrawal. J Clin Psychopharmacol 1983 0.82
42 Experimental keloid scar models: a review of methodological issues. J Cutan Med Surg 2002 0.82
43 Ranitidine kinetics and dynamics. II. Intravenous dose studies and comparison with cimetidine. Clin Pharmacol Ther 1981 0.81
44 Digoxin toxicity associated with amiodarone therapy in children. J Pediatr 1984 0.81
45 Pharmacokinetics of intravenous clindamycin in newborn infants. Pediatr Pharmacol (New York) 1986 0.81
46 Endogenous digoxin-like substance(s) associated with uneventful and high-risk pregnancies. Dev Pharmacol Ther 1988 0.81
47 Letter: Propranolol effect on tremor in alcoholic withdrawal. Ann Intern Med 1975 0.80
48 Organization and efficacy of a therapeutic drug monitoring consultation service in a pediatric hospital. Ther Drug Monit 1985 0.80
49 Difficulty in achieving therapeutic serum concentrations of salicylate in Kawasaki disease. J Pediatr 1984 0.80
50 Postmortem redistribution of digoxin in rats. J Forensic Sci 1985 0.80
51 A rapid high performance liquid chromatographic procedure for the analysis of cloxacillin and/or nafcillin in serum. Ther Drug Monit 1980 0.80
52 Letter: Effect of propranolol on tremor of alcohol withdrawal. N Engl J Med 1976 0.78
53 Altered PABA pharmacokinetics in cystic fibrosis. Implications for bentiromide test. Dig Dis Sci 1985 0.78
54 Antihypertensive efficacy of propranolol given twice daily. Can Med Assoc J 1979 0.78
55 Kinetics of CSF phenytoin in children. Can J Neurol Sci 1983 0.78
56 Cerebrospinal fluid pharmacokinetics of tobramycin, ceftazidime, phenobarbitone and phenytoin in a child. Clin Pharmacokinet 1985 0.78
57 Analysis of methotrexate and 7-hydroxymethotrexate by high-performance liquid chromatography and preliminary clinical studies. Ther Drug Monit 1982 0.77
58 Theophylline. New thoughts about an old drug. Chest 1982 0.77
59 Science and politics: two solitudes. Clin Invest Med 1986 0.77
60 Pediatric fentanyl dosing based on pharmacokinetics during cardiac surgery. Anesth Analg 1984 0.77
61 Propranolol and chlordiazepoxide effects on cardiac arrhythmias during alcohol withdrawal. Alcohol Clin Exp Res 1980 0.77
62 The WHO. The tropical disease research programme has a coherent plan. BMJ 1995 0.75
63 Prescription data. CMAJ 2001 0.75
64 Drug information for patients. Can Med Assoc J 1979 0.75
65 Basic science in medical education. Clin Invest Med 1999 0.75
66 Undergraduate medical education. Too many facts not enough innovation. BMJ 1993 0.75
67 When is a market not a market? CMAJ 1993 0.75
68 Interaction of cimetidine and theophylline in two infants. Can Med Assoc J 1982 0.75
69 Pemoline pharmacokinetics and long term therapy in children with attention deficit disorder and hyperactivity. Clin Pharmacokinet 1985 0.75
70 Clinical pharmacology in a paediatric hospital. Dimens Health Serv 1979 0.75
71 Influence of specific gravity on intravenous drug delivery. J Pediatr 1981 0.75
72 Analysis of morphine in serum by high performance liquid chromatography with amperometric detection. Ther Drug Monit 1982 0.75
73 Adverse drug reactions: an integrated approach. Bratisl Lek Listy 1991 0.75
74 Comparison of methods for prediction of nephrotoxicity during development. Dev Pharmacol Ther 1992 0.75
75 Absence of tachyphylaxis in gastric acid secretion during pentagastrin infusion. J Clin Pharmacol 1986 0.75
76 Anti-allergy and anti-asthma drugs. Disposition in infancy and childhood. Clin Pharmacokinet 1989 0.75
77 Use of the overturn end point in goldfish to measure the interaction of diazepam and ethanol and the effects of the binding of diazepam to bovine serum albumin. Can J Physiol Pharmacol 1979 0.75
78 Comparative bioavailability study of three sustained release quinidine formulations. Clin Pharmacokinet 1987 0.75
79 Interaction of digoxin with verapamil, indomethacin, and other coadministered drugs: a comparative study in rat tissue. Prog Clin Biol Res 1983 0.75
80 Canadian aid as a catalyst to improved East African health care. CMAJ 1986 0.75
81 Canadian Society for Clinical Investigation representation to the Eastman Commission: research and development in the pharmaceutical industry--a Sisyphyian tale. Clin Invest Med 1986 0.75
82 Alcohol use by patients admitted to hospital emergency rooms for treatment of drug overdose and misuse. J Stud Alcohol 1980 0.75
83 Digoxin-verapamil interaction: in vitro studies in rat tissue. J Cardiovasc Pharmacol 1983 0.75
84 Electrocardiographic changes during ethanol withdrawal. Ann N Y Acad Sci 1976 0.75
85 The rational use of potassium supplements. Postgrad Med 1975 0.75
86 Evaluating a filter device used for intermittent intravenous drug delivery to newborn infants. Am J Hosp Pharm 1985 0.75
87 Theophylline pharmacokinetics in adolescent females following coadministration of oral contraceptives. Clin Invest Med 1985 0.75
88 Pharmacokinetics of cimetidine in critically ill children. Pediatr Pharmacol (New York) 1982 0.75
89 Survey of Canadian hospital-based and private pediatricians on clinical pharmacology. J Med Educ 1986 0.75
90 Determinants of drug disposition in man. Clin Biochem 1986 0.75
91 Interaction of disulfiram with benzodiazepines. Clin Pharmacol Ther 1978 0.75
92 Inhibition of hepatic microsomal drug metabolism by the hydrazines Ro 4-4602, MK 486, and procarbazine hydrochloride. Can J Physiol Pharmacol 1972 0.75
93 Pharmacokinetics of fentanyl in children with renal disease. Res Commun Chem Pathol Pharmacol 1984 0.75
94 Biomedical research: who will pay the piper? Can Med Assoc J 1985 0.75
95 Influence of bioavailability on the calculated Michaelis-Menten parameters of phenytoin in children. Ther Drug Monit 1984 0.75
96 Analysis of pemoline in serum by high performance liquid chromatography: clinical application to optimize treatment of hyperactive children. Ther Drug Monit 1980 0.75
97 Characteristics of the digoxin-quinidine and digoxin-verapamil interactions in the rat kidney. Res Commun Chem Pathol Pharmacol 1984 0.75
98 Potentiation of bishydroxycoumarin in dogs by isoniazid and p-aminosalicylic acid. Am Rev Respir Dis 1971 0.75
99 Faculty attitudes toward various teaching formats at two Canadian medical schools. Acad Med 1991 0.75
100 High-pressure liquid chromatographic assay of cloxacillin in serum and urine. J Pharm Sci 1982 0.75
101 Unexpected alterations in fentanyl pharmacokinetics in children undergoing cardiac surgery: age related or disease related? Dev Pharmacol Ther 1986 0.75
102 The high performance liquid chromatographic measurement of chloramphenicol and its succinate esters in serum. Clin Biochem 1983 0.75
103 Pharmacokinetics of cimetidine after subchronic administration. Eur J Clin Pharmacol 1986 0.75
104 Centrally acting sympatholytic agents in the treatment of congestive heart failure. A review of the literature. Drugs 1990 0.75
105 Optimization of gentamicin therapy in very low birth weight infants. Pediatr Pharmacol (New York) 1985 0.75