PubRank

K Yonezawa

Author PubWeight™ 102.88‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J Biol Chem 1998 9.37
2 Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr Biol 1994 3.44
3 PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity. EMBO J 1994 3.39
4 1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cells. Proc Natl Acad Sci U S A 1994 3.37
5 Insulin and amino-acid regulation of mTOR signaling and kinase activity through the Rheb GTPase. Oncogene 2006 3.18
6 PI 3-kinase: structural and functional analysis of intersubunit interactions. EMBO J 1994 3.02
7 Involvement of phosphoinositide 3-kinase in insulin- or IGF-1-induced membrane ruffling. EMBO J 1994 2.81
8 Regulation of eIF-4E BP1 phosphorylation by mTOR. J Biol Chem 1997 2.73
9 Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J Biol Chem 1999 2.65
10 Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro. J Biol Chem 1999 2.49
11 Phosphatidylinositol kinase or an associated protein is a substrate for the insulin receptor tyrosine kinase. J Biol Chem 1990 2.35
12 Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin. Biochem J 1994 2.30
13 Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon. J Biol Chem 1999 1.90
14 Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. J Biol Chem 1998 1.74
15 The p70 S6 kinase integrates nutrient and growth signals to control translational capacity. Prog Mol Subcell Biol 2001 1.71
16 Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin. J Biol Chem 2001 1.69
17 Insulin activates the kinase activity of the Raf-1 proto-oncogene by increasing its serine phosphorylation. J Biol Chem 1990 1.49
18 Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells. Mol Cell Biol 1995 1.36
19 Regulation of protein phosphatase 2A catalytic activity by alpha4 protein and its yeast homolog Tap42. Biochem Biophys Res Commun 1998 1.34
20 Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck. Biochem Biophys Res Commun 1996 1.34
21 Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro. Genes Cells 2000 1.32
22 Analysis of thermal injury-induced insulin resistance in rodents. Implication of postreceptor mechanisms. J Biol Chem 1997 1.29
23 Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-L1 adipocytes. Biochem Biophys Res Commun 1995 1.23
24 Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells. J Biol Chem 1995 1.16
25 A biosensor approach to probe the structure and function of the p85 alpha subunit of the phosphatidylinositol 3-kinase complex. J Biol Chem 1993 1.14
26 Alpha4 protein as a common regulator of type 2A-related serine/threonine protein phosphatases. FEBS Lett 1999 1.07
27 Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85kD subunit of phosphoinositide 3-kinase. Biochem Biophys Res Commun 1995 1.05
28 Characterization of the phosphoproteins and protein kinase activity in mTOR immunoprecipitates. Biochem Biophys Res Commun 1998 1.05
29 Structural requirement of leucine for activation of p70 S6 kinase. FEBS Lett 1999 1.05
30 Skeletal muscle metabolism limits exercise capacity in patients with chronic heart failure. Circulation 1998 1.02
31 A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. EMBO J 1994 1.00
32 Phosphoinositide 3-kinase as an upstream regulator of the small GTP-binding protein Rac in the insulin signaling of membrane ruffling. Biochem Biophys Res Commun 1995 0.98
33 Gastric non-Hodgkin's lymphoma associated with Behçet's disease. Intern Med 1993 0.94
34 Protein-free cell culture on an artificial substrate with covalently immobilized insulin. Proc Natl Acad Sci U S A 1996 0.94
35 Effects of geranyl-geranyl-acetone administration before heat shock preconditioning for conferring tolerance against ischemia-reperfusion injury in rat livers. J Lab Clin Med 2000 0.92
36 Destruction of pancreatic islet cells by cytotoxic T lymphocytes in nonobese diabetic mice. J Immunol 1989 0.91
37 Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha. Genes Cells 2001 0.91
38 Spontaneous dissecting aneurysms of the basilar artery presenting with a subarachnoid hemorrhage. Report of two cases. J Neurosurg 1991 0.91
39 MR imaging of spinal neurinomas with pathological correlation. J Comput Assist Tomogr 1990 0.90
40 Pancreatic-colonic fistula successfully treated with endoscopic transpapillary nasopancreatic drainage. Endoscopy 2011 0.89
41 Thoracic extramedullary hematopoiesis associated with hereditary spherocytosis. Intern Med 1992 0.88
42 Dissociation between muscle metabolism and oxygen kinetics during recovery from exercise in patients with chronic heart failure. Heart 2000 0.85
43 In situ pedicle resection in left trisegmentectomy of the liver combined with reconstruction of the right hepatic vein to an inferior vena caval segment transpositioned from the infrahepatic portion. J Am Coll Surg 2001 0.85
44 Expression of insulin receptor substrate-1 in hepatocytes: an investigation using monoclonal antibodies. Cancer Lett 1994 0.84
45 Insulin-like growth factor I receptor activated by a transmembrane mutation. J Biol Chem 1995 0.84
46 Assignment of Bacillus thermoamyloliquefaciens KP1071 alpha-glucosidase I to an exo-alpha-1,4-glucosidase, and its striking similarity to bacillary oligo-1,6-glucosidases in N-terminal sequence and in structural parameters calculated from the amino acid composition. Eur J Biochem 1992 0.83
47 Frequent expression of the c-kit proto-oncogene in canine malignant mammary tumor. J Vet Med Sci 1998 0.82
48 A novel transmembrane semaphorin can bind c-src. Mol Cell Neurosci 1997 0.81
49 Cellular localization of insulin-degrading enzyme in rat liver using monoclonal antibodies specific for this enzyme. Biochem Biophys Res Commun 1988 0.81
50 [A case of gastric malignant schwannoma]. Nihon Shokakibyo Gakkai Zasshi 1994 0.81
51 Possible role of cell surface insulin degrading enzyme in cultured human lymphocytes. Diabetologia 1987 0.81
52 The first case of polymyositis associated with interferon therapy. Intern Med 1994 0.80
53 Degradation of insulin by insulin-degrading enzyme and biological characteristics of its fragments. Endocrinology 1986 0.80
54 Phosphorylation sites of myelin basic protein by a catalytic fragment of non-receptor type protein-tyrosine kinase p72syk and comparison with those by insulin receptor kinase. Biochem Biophys Res Commun 1993 0.80
55 Immunochemical characterization of anti-islet cell surface monoclonal antibody from nonobese diabetic mice. Diabetes 1986 0.80
56 Influence of motor activities on the release of transmitter quanta from motor nerve terminals in mice. J Vet Med Sci 1999 0.79
57 Unexplained melena associated with a history of endovascular stent grafting of abdominal aortic aneurysms: aortoduodenal fistula. Endoscopy 2009 0.79
58 [Effects of mesalazine on liver carcinogenesis in medium-term bioassay using rats]. J Toxicol Sci 1998 0.78
59 Substitution of glutamine for arginine 1131. A newly identified mutation in the catalytic loop of the tyrosine kinase domain of the human insulin receptor. J Biol Chem 1994 0.78
60 Antimetastatic and antitumor effect of a recombinant human tissue inhibitor of metalloproteinases-2 in murine melanoma models. Biol Pharm Bull 1997 0.78
61 A simple ergometer for 31P NMR spectroscopy during dynamic forearm exercise in a whole body magnetic resonance imaging system. Jpn Heart J 1992 0.78
62 Phosphorus-31 magnetic resonance spectroscopy of forearm flexor muscles in student rowers using an exercise protocol adjusted for differences in cross-sectional muscle area. Eur J Appl Physiol Occup Physiol 1992 0.78
63 Skeletal muscle metabolism in maximal bicycle and treadmill exercise distinguished by using in vivo metabolic freeze method and phosphorus-31 magnetic resonance spectroscopy in normal men. Am J Cardiol 1998 0.78
64 Exogenous superoxide dismutase prevents peroxynitrite-induced apoptosis in non-heart-beating donor livers. Eur Surg Res 2008 0.77
65 Translocation, activation and association of protein-tyrosine kinase (p72syk) with phosphatidylinositol 3-kinase are early events during platelet activation. Eur J Biochem 1994 0.77
66 Cell surface receptor function of amyloid precursor protein that activates Ser/Thr kinases. Gerontology 1996 0.77
67 Expression patterns of the erbB subfamily mRNA in canine benign and malignant mammary tumors. J Vet Med Sci 2001 0.77
68 Muscle high-energy metabolites and metabolic capacity in patients with heart failure. Med Sci Sports Exerc 2001 0.77
69 Affinity purification of insulin-degrading enzyme and its endogenous inhibitor from rat liver. J Biol Chem 1992 0.77
70 Meloxicam, a COX-2 inhibitor, ameliorates ischemia/reperfusion injury in non-heart-beating donor livers. Eur Surg Res 2011 0.77
71 Metabolic abnormality of calf skeletal muscle is improved by localised muscle training without changes in blood flow in chronic heart failure. Heart 1997 0.77
72 [Insulin receptor Arg1131-->Gln: a novel mutation in the catalytic loop of insulin receptor observed in insulin resistant diabetes]. Nihon Geka Gakkai Zasshi 1992 0.77
73 [Cellular immune dysfunction in the NOD mouse: suppression of concanavalin A-induced responses in spleen cells by activated macrophages]. Nihon Naibunpi Gakkai Zasshi 1989 0.77
74 Effects of raloxifene on adipocytokines in Japanese osteoporotic postmenopausal women with and without type 2 diabetes. Horm Metab Res 2006 0.77
75 Serum antibody reacting with placental syncytiotrophoblast in sera of patients with autoimmune diseases--a possible relation to type C RNA retrovirus. Clin Exp Immunol 1985 0.77
76 Leukemia serum reactive with retrovirus-related antigen in normal human placenta. Int J Cancer 1986 0.76
77 Ventilatory anaerobic threshold before and after cardiac valve surgery. Jpn Circ J 1993 0.76
78 Biological studies on mikamycin. V. Absorption and excretion of tritiated mikamycins A and B. J Antibiot (Tokyo) 1970 0.76
79 [Interstitial pneumonitis associated with ulcerative colitis: a case report and review of the literature]. Nihon Shokakibyo Gakkai Zasshi 1993 0.75
80 Prophylactic perioperative treatment in a patient with colon carcinoma complicated by polycythemia vera. Hepatogastroenterology 1997 0.75
81 Multiplicity of phosphate acceptor proteins for muscle glycogen phosphorylase kinase. J Biochem 1980 0.75
82 [Glucose metabolism on intravenous glucose tolerance test in obstructive jaundice (author's transl)]. Nihon Shokakibyo Gakkai Zasshi 1980 0.75
83 [Posterior proctomucosectomy and ileal pull-through reconstruction: a new restorative procedure after total proctocolectomy]. Nihon Geka Hokan 1994 0.75
84 [Lipid peroxidation in the irradiated lung of a mouse]. Nihon Igaku Hoshasen Gakkai Zasshi 1987 0.75
85 Effect of antiserum to monoclonal anti-islet cell surface antibody on pancreatic insulitis in non-obese diabetic mice. Diabetes Res Clin Pract 1986 0.75
86 [A synthetic luteinizing hormone releasing hormone (LH-RH) loading test on male sterility (author's transl)]. Nihon Hinyokika Gakkai Zasshi 1973 0.75
87 Changes in plasma levels of LH, FSH and testosterone following the administration of synthetic luteinizing hormone-releasing hormone to cryptorchid patients. Tohoku J Exp Med 1975 0.75
88 [Serum growth hormone determination with a radioimmunoassay kit]. Horumon To Rinsho 1978 0.75
89 [Serum triiodothyronine determination with an radioimmunoassay kit]. Horumon To Rinsho 1979 0.75
90 Effects of ejaculation induced by manual stimulation on plasma gonadotropin and testosterone levels in infertile man. Tohoku J Exp Med 1974 0.75
91 Cytomegalovirus gastritis after treatment with rituximab. Endoscopy 2009 0.75
92 [An autopsied case of progressive systemic sclerosis with anti Wa antibody who showed a rapid progression]. Ryumachi 1992 0.75
93 [Histopathological study of the esophageal injury induced by high-dose-rate intracavitary irradiation]. Nihon Igaku Hoshasen Gakkai Zasshi 1991 0.75
94 [A case with juvenile rheumatoid arthritis who developed cerebral vasculitis and venovascular hypertension]. Ryumachi 2000 0.75
95 Suppressor T-cell abnormality in NOD mice before onset of diabetes. Diabetes Res Clin Pract 1989 0.75
96 [Clinical study of preoperative radiotherapy of bladder cancer]. Nihon Gan Chiryo Gakkai Shi 1990 0.75
97 [Clinical aspects of ulcerative colitis with special reference to symptoms, signs and laboratory data]. Nihon Rinsho 1999 0.75
98 [Metabolic studies on polychlorinated biphenyls. VII. Metabolic fate of 2,5,2',5'-tetrachlorobiphenyl in rats(author's transl)]. Fukuoka Igaku Zasshi 1975 0.75
99 Myocardial high-energy phosphate metabolism in patients with stable chronic dilated cardiomyopathy under a dobutamine-induced prolonged mild workload. Am Heart J 1999 0.75
100 Distribution of secretory component in non-cancerous human gastric mucosa. Gastroenterol Jpn 1983 0.75
101 [Clinical study on development factors of radiation pneumonitis]. Gan No Rinsho 1990 0.75
102 [Clinical and experimental studies on a new intrabronchial infusion therapy of immunopotentiator-OK-432 in lung cancer]. Nihon Gan Chiryo Gakkai Shi 1986 0.75
103 [Influence of hepatic arterial embolization on diabetic patients with hepatocellular carcinoma]. Nihon Igaku Hoshasen Gakkai Zasshi 1989 0.75
104 [Rapidly enlarging giant left ventricular pseudo-false aneurysm after myocardial infarction; report of a case]. Kyobu Geka 2006 0.75
105 [A recovered case of SLE with central nervous system involvement who relapsed presenting new symptoms associated with development of serum anti-Sm antibody]. Ryumachi 1998 0.75
106 Replacement of L-T4 suppository in MMI treated rabbits. Endocrinol Jpn 1990 0.75
107 High-performance liquid chromatography of a new beta-blocker, 4-[3-(tert.-butylamino)-2-hydroxypropoxy]-N-methylisocarbostyril hydrochloride, in plasma using fluorometric detection. J Chromatogr 1985 0.75
108 Synergistic value of fibrinolysis and hypothermic aerobic preservation with oxygen in the protection of livers from non-heart-beating donors: an experimental model. Transplant Proc 2004 0.75
109 [Clinical experience with fluorocoat ointment]. Acta Dermatol Kyoto Engl Ed 1967 0.75
110 [Strangulation ileus with hepatic portal vein gas, a case report (author's transl)]. Rinsho Hoshasen 1977 0.75
111 [Effect of factor XIII on intractable CSF leakage after a transpetrosal-approach operation: a case report]. No Shinkei Geka 1997 0.75
112 [Study of the new useful electrophysiological parameter in diagnosing carpal tunnel syndrome associated with diabetes mellitus]. Rinsho Byori 1988 0.75
113 [Experimental studies with prolactin radioimmunoassay kit]. Horumon To Rinsho 1977 0.75
114 [Parenteral replacement of 1-T4 in hypothyroid patients with esophageal stenosis and unconsciousness]. Nihon Naibunpi Gakkai Zasshi 1993 0.75
115 A one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases-2. Contrib Nephrol 1994 0.75
116 Antagonistic effects of atipamezole on medetomidine-induced sedation in horses. J Vet Med Sci 1996 0.75
117 [Radiation-induced expression of Ia antigens and lymphocyte infiltration in murine tumors]. Nihon Igaku Hoshasen Gakkai Zasshi 1988 0.75
118 [Clinical experiences with pyrrolnitrin ointment and spray in dermatomycosis]. Acta Dermatol Kyoto Engl Ed 1968 0.75
119 Internalization and degradation of insulin by a human insulin receptor-v-ros hybrid in Chinese hamster ovary cells. Biochem Biophys Res Commun 1989 0.75
120 [Prolactin producing adenoma]. Nihon Rinsho 1993 0.75
121 [A case of hyperthyroidism appeared during interferon treatment for chronic hepatitis C]. Nihon Shokakibyo Gakkai Zasshi 1993 0.75
122 Inhibitory and stimulatory effects of guanyl-5'-yl imidodiphosphate on the adenylate cyclase activity of rat synaptosomal fractions. J Biochem 1980 0.75
123 [Determination of serum thyrotropin (TSH) with a radioimmunoassay kit]. Horumon To Rinsho 1977 0.75
124 Acute fulminant ulcerative colitis with toxic megacolon. Acta Paediatr Jpn 1997 0.75
125 [Effect of hormonal therapy on plasma FSH, LH and testosterone levels in prostatic cancer]. Nihon Hinyokika Gakkai Zasshi 1975 0.75
126 Changes in plasma levels of FSH, LH and testosterone during anti-androgenic hormone therapy for patients with prostatic cancer. Tohoku J Exp Med 1974 0.75
127 [Improved analysis of serrapeptase by high performance steric exclusion chromatography (SEC). I]. Yakugaku Zasshi 1986 0.75
128 Facile cleavage of RNA via phosphodiester linkage fission by Co(III) complex. Nucleic Acids Symp Ser 1990 0.75
129 [A case of acute emphysematous cholecystitis showing atypical gas distributions]. Nihon Shokakibyo Gakkai Zasshi 1994 0.75
130 [Pharmacodynamic effects of ionic and non-ionic contrast media]. Rinsho Hoshasen 1988 0.75
131 [Application of CT simulation system to stereotactic radiosurgery--experimental study in phantoms]. Nihon Igaku Hoshasen Gakkai Zasshi 1992 0.75
132 Desquamative esophagitis due to pemphigus vulgaris. Endoscopy 2010 0.75
133 [Whole blood method for evaluating lymphocyte responses to PHA and PWM (author's transl)]. Kaku Igaku 1977 0.75
134 FSH, LH and testosterone levels in human seminal plasma. Tohoku J Exp Med 1975 0.75
135 [Assessment of thyroid function by the Phadebas T4 RIA (author's transl)]. Horumon To Rinsho 1980 0.75
136 The elusive benzocyclobutenylidene: a combined computational and experimental attempt. J Am Chem Soc 2001 0.75
137 [Congestive liver associated with valvular heart disease--clinical and experimental studies]. Kyobu Geka 1987 0.75
138 [Clinical experience with MDS in dermatologic diseases]. Acta Dermatol Kyoto Engl Ed 1967 0.75
139 Regulation of biological functions by insulin and insulin-like growth factor I via their own distinct receptors. Diabetes Res Clin Pract 1989 0.75
140 [Serum AFP determination by polyethylene glycol method]. Horumon To Rinsho 1978 0.75
141 [A case of systemic lupus erythematosus developed with intestinal perforation]. Ryumachi 1998 0.75
142 [Evaluation of rapid sequence CT scan with intravenous bolus injection of a contrast medium in the diagnosis of pancreatic disease]. Rinsho Hoshasen 1988 0.75
143 [A case report of Swyer-James syndrome]. Rinsho Hoshasen 1989 0.75
144 [Neurilemmoma of lesser omentum]. Rinsho Hoshasen 1989 0.75