Published in Circulation on September 05, 2000
Placebo Controlled Trial of Bosentan in Scleroderma Patients | NCT00377455
Exercise-induced pulmonary arterial hypertension. Circulation (2008) 2.80
Accuracy of noninvasively determined pulmonary artery systolic pressure. Am J Cardiol (2010) 1.56
Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions. Am J Physiol Lung Cell Mol Physiol (2008) 1.47
Pulmonary arterial hypertension: a comparison between children and adults. Eur Respir J (2011) 1.36
Exercise-induced pulmonary hypertension: physiological basis and methodological concerns. Am J Respir Crit Care Med (2013) 1.23
Exercise stress echocardiography for the study of the pulmonary circulation. Eur Respir J (2009) 1.15
The adult patient with eisenmenger syndrome: a medical update after dana point part I: epidemiology, clinical aspects and diagnostic options. Curr Cardiol Rev (2010) 1.06
Genetics and mediators in pulmonary arterial hypertension. Clin Chest Med (2007) 1.06
Hemodynamic and clinical onset in patients with hereditary pulmonary arterial hypertension and BMPR2 mutations. Respir Res (2011) 1.01
Idiopathic and heritable PAH perturb common molecular pathways, correlated with increased MSX1 expression. Pulm Circ (2011) 1.00
Value of MR phase-contrast flow measurements for functional assessment of pulmonary arterial hypertension. Eur Radiol (2007) 0.98
Autoimmunity and pulmonary hypertension in patients with Graves' disease. Heart Vessels (2014) 0.97
Pulmonary hypertension associated with COPD. Crit Care (2001) 0.96
Effects of the main green tea polyphenol epigallocatechin-3-gallate on cardiac involvement in patients with AL amyloidosis. Clin Res Cardiol (2010) 0.92
Pulmonary artery pressure in lymphangioleiomyomatosis: an echocardiographic study. Chest (2007) 0.92
Pulmonary arterial hypertension: new ideas and perspectives. Heart (2001) 0.88
Hemodynamic and genetic analysis in children with idiopathic, heritable, and congenital heart disease associated pulmonary arterial hypertension. Respir Res (2013) 0.85
New insights into the pathogenesis and treatment of primary pulmonary hypertension. Thorax (2001) 0.82
Stress Doppler echocardiography for early detection of systemic sclerosis-associated pulmonary arterial hypertension. Arthritis Res Ther (2015) 0.81
WEB downloadable software for training in cardiovascular hemodynamics in the (3-D) stress echo lab. Cardiovasc Ultrasound (2010) 0.80
How to measure peripheral pulmonary vascular mechanics. Conf Proc IEEE Eng Med Biol Soc (2009) 0.78
Identification of a new intronic BMPR2-mutation and early diagnosis of heritable pulmonary arterial hypertension in a large family with mean clinical follow-up of 12 years. PLoS One (2014) 0.78
Genome wide expression analysis suggests perturbation of vascular homeostasis during high altitude pulmonary edema. PLoS One (2014) 0.77
Non-invasive quantification of right ventricular systolic function by echocardiography: a new semi-automated approach. Clin Res Cardiol (2012) 0.76
[Diagnosis and therapy of chronic pulmonary hypertension]. Clin Res Cardiol (2007) 0.75
EIF2AK4 mutation as "second hit" in hereditary pulmonary arterial hypertension. Respir Res (2016) 0.75
Impact of age on pulmonary artery systolic pressures at rest and with exercise. Echo Res Pract (2016) 0.75
Mechanisms of exercise-induced pulmonary hypertension in patients with cardiac septal defects. Pediatr Cardiol (2012) 0.75
Contractile reserve in systemic sclerosis patients as a major predictor of global cardiac impairment and exercise tolerance. Int J Cardiovasc Imaging (2014) 0.75
Assessing pulmonary arterial hypertension in infants with severe chronic lung disease of infancy: a role for a pulmonary artery catheter? Pediatr Cardiol (2013) 0.75
Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence. Nat Genet (2000) 14.51
Haplotype sharing analysis using mantel statistics. Hum Hered (2005) 6.76
Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34. Science (1997) 6.10
Miltefosine, an oral agent, for the treatment of Indian visceral leishmaniasis. N Engl J Med (1999) 5.02
Alternative polyadenylation events contribute to the induction of NF-ATc in effector T cells. Immunity (1999) 3.69
Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J (2009) 3.31
Small-bowel diverticulosis: perceptions and reality. J Am Coll Surg (1997) 3.09
Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells. Chromosome Res (2001) 2.89
Frequency and phenotypes of familial dilated cardiomyopathy. J Am Coll Cardiol (1998) 2.73
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Sildenafil treatment for portopulmonary hypertension. Eur Respir J (2006) 2.58
Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea. Impact of continuous positive airway pressure therapy. Am J Respir Crit Care Med (2000) 2.55
Therapeutic efficacy of sulfasalazine and its metabolites in patients with ulcerative colitis and Crohn's disease. N Engl J Med (1980) 2.39
Hearing preservation in acoustic neurinoma surgery. J Neurosurg (1992) 2.33
Is the 6-minute walk test a reliable substitute for peak oxygen uptake in patients with dilated cardiomyopathy? Eur Heart J (2000) 2.16
Physical training in patients with stable chronic heart failure: effects on cardiorespiratory fitness and ultrastructural abnormalities of leg muscles. J Am Coll Cardiol (1995) 2.11
Various intensities of leisure time physical activity in patients with coronary artery disease: effects on cardiorespiratory fitness and progression of coronary atherosclerotic lesions. J Am Coll Cardiol (1993) 2.10
Oscillatory synchrony between human extrastriate areas during visual short-term memory maintenance. J Neurosci (2001) 2.08
The effect of aortic valve replacement on survival. Circulation (1982) 2.03
Neuromonitoring during surgery. Report of an IFCN Committee. Electroencephalogr Clin Neurophysiol (1993) 1.93
Laparoscopic nephrectomy: the experience of the laparoscopy working group of the German Urologic Association. J Urol (1998) 1.93
Shanxi Province Cervical Cancer Screening Study: a cross-sectional comparative trial of multiple techniques to detect cervical neoplasia. Gynecol Oncol (2001) 1.93
Sporadic imprinting defects in Prader-Willi syndrome and Angelman syndrome: implications for imprint-switch models, genetic counseling, and prenatal diagnosis. Am J Hum Genet (1998) 1.87
Angiotensin induces inflammatory activation of human vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (1999) 1.86
Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis. Mol Cell Biol (1995) 1.85
Intravascular ultrasound assessment of lumen size and wall morphology in normal subjects and patients with coronary artery disease. Circulation (1991) 1.83
Pulmonary vascular resistances during exercise in normal subjects: a systematic review. Eur Respir J (2011) 1.77
Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia. J Med Genet (2003) 1.76
Long-term outcomes of chronic minimally conscious and vegetative states. Neurology (2010) 1.76
A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. J Am Coll Cardiol (2000) 1.73
Radioiodine therapy of Graves' hyperthyroidism: standard vs. calculated 131iodine activity. Results from a prospective, randomized, multicentre study. Eur J Clin Invest (1995) 1.73
Reduced coronary dilatory capacity and ultrastructural changes of the myocardium in patients with angina pectoris but normal coronary arteriograms. Circulation (1981) 1.68
Evidence for linkage of spelling disability to chromosome 15. Am J Hum Genet (1998) 1.65
Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature (1996) 1.65
Long-term efficacy of gamma knife radiosurgery in mesial temporal lobe epilepsy. Neurology (2008) 1.64
Respiratory muscle dysfunction in congestive heart failure: clinical correlation and prognostic significance. Circulation (2001) 1.64
Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (alphaIIbbeta3) inhibitors. Blood (1998) 1.61
Development and characterization of a rapid assay for bedside determinations of cardiac troponin T. Circulation (1995) 1.61
Searching for the exercise factor: is IL-6 a candidate? J Muscle Res Cell Motil (2003) 1.60
Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18). Circulation (1999) 1.58
Characterization and repeat analysis of the compact genome of the freshwater pufferfish Tetraodon nigroviridis. Genome Res (2000) 1.57
Four-year follow-up study in patients with angina pectoris and normal coronary arteriograms ("syndrome X") Circulation (1989) 1.57
Regulation of glycolysis in the ischemic and the anoxic myocardium. J Mol Cell Cardiol (1970) 1.52
Do cytokines enable risk stratification to be improved in NYHA functional class III patients? Comparison with other potential predictors of prognosis. Eur Heart J (2002) 1.51
Prostacyclin therapies for the treatment of pulmonary arterial hypertension. Eur Respir J (2008) 1.48
[Sildenafil for treatment of severe pulmonary hypertension and commencing right-heart failure]. Pneumologie (2002) 1.48
Attenuated progression of coronary artery disease after 6 years of multifactorial risk intervention: role of physical exercise. Circulation (1997) 1.48
Nicotine and sympathetic neurotransmission. Cardiovasc Drugs Ther (1997) 1.47
Increased activity of membrane-associated nucleoside diphosphate kinase and inhibition of cAMP synthesis in failing human myocardium. Cardiovasc Res (2001) 1.46
The metabolic role of IL-6 produced during exercise: is IL-6 an exercise factor? Proc Nutr Soc (2004) 1.45
ACE inhibition improves vagal reactivity in patients with heart failure. Am Heart J (1990) 1.45
Enzyme linked immuno assay of cardiac troponin T for the detection of acute myocardial infarction in patients. J Mol Cell Cardiol (1989) 1.45
A selective imaging of tinnitus. Neuroreport (1999) 1.44
Autonomic nervous system and neuroendocrine changes in patients with idiopathic trigeminal neuralgia. Cephalalgia (1996) 1.44
Lateralization in autonomic dysfunction in ischemic stroke involving the insular cortex. Neuroreport (2004) 1.44
[Diagnosis of vitamin B12 deficiency revised]. Ned Tijdschr Geneeskd (2005) 1.43
Noninvasive assessment of regional cardiac adenosine using positron emission tomography. J Nucl Med (1992) 1.41
[Fifteen practical questions concerning gestational diabetes]. Gynecol Obstet Fertil (2007) 1.41
Treatment of American cutaneous leishmaniasis with miltefosine, an oral agent. Clin Infect Dis (2001) 1.41
External beam radiation after stent implantation increases neointimal hyperplasia by augmenting smooth muscle cell proliferation and extracellular matrix accumulation. J Am Coll Cardiol (1999) 1.41
Preventing progression to first-episode psychosis in early initial prodromal states. Br J Psychiatry (2011) 1.40
Refractory oedema in congestive heart failure: a contributory role of loop diuretics? J Intern Med (1995) 1.40
Baroreceptor-mediated release of vasopressin in patients with chronic congestive heart failure and defective sympathetic responsiveness. Am J Cardiol (1992) 1.39
[What is the recurrence rate for Basedow's disease treated with thyrostatic agents. Answers from a prospective study]. Schweiz Med Wochenschr (1990) 1.39
[Chemoprevention of prostate cancer - a plea]. Aktuelle Urol (2012) 1.39
Comparison of captopril with enalapril in the treatment of heart failure: influence on hemodynamics and measures of renal function. Cardiovasc Drugs Ther (1992) 1.39
Is the "candy-wrapper" effect of (32)P radioactive beta-emitting stents due to remodeling or neointimal hyperplasia? Insights from intravascular ultrasound. Catheter Cardiovasc Interv (2001) 1.38
Myocardial scintigraphy with iodine-123 phenylpentadecanoic acid and thallium-201 in patients with coronary artery disease: a comparative dual-isotope study. Eur J Nucl Med (1992) 1.38
Release of endogenous catecholamines in the ischemic myocardium of the rat. Part A: Locally mediated release. Circ Res (1984) 1.38
Deletion of protein kinase A phosphorylation sites in the HERG potassium channel inhibits activation shift by protein kinase A. J Biol Chem (1999) 1.37
Differential activation of mitogen-activated protein kinases in smooth muscle cells by angiotensin II: involvement of p22phox and reactive oxygen species. Arterioscler Thromb Vasc Biol (2000) 1.36
Novel splice donor site mutation in the cardiac myosin-binding protein-C gene in familial hypertrophic cardiomyopathy. Characterization Of cardiac transcript and protein. J Clin Invest (1997) 1.36
Genetic and biochemical analysis of Staphylococcus epidermidis biofilm accumulation. Methods Enzymol (2001) 1.34
Recognition of distress and psychiatric morbidity in cancer patients: a multi-method approach. Ann Oncol (2004) 1.34
Cloning, genomic organization, alternative transcripts and mutational analysis of the gene responsible for autosomal recessive universal congenital alopecia. Hum Mol Genet (1998) 1.34
Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology. Virology (2000) 1.32
Circulating vascular cell adhesion molecule-1 correlates with the extent of human atherosclerosis in contrast to circulating intercellular adhesion molecule-1, E-selectin, P-selectin, and thrombomodulin. Arterioscler Thromb Vasc Biol (1997) 1.30
Rodents as shared indicators for zoonotic parasites of carnivores in urban environments. Parasitology (2009) 1.30
Short-course of oral miltefosine for treatment of visceral leishmaniasis. Clin Infect Dis (2000) 1.29
Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy. Thorax (2000) 1.27
Exploring haplotype sharing methods in general and isolated populations to detect gene(s) of a complex genetic trait. Genet Epidemiol (2001) 1.26
A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance. Circulation (2000) 1.26
Effect of dexamethasone on in vivo prostanoid production in the rabbit. J Clin Invest (1984) 1.24
Reduction of coronary reserve: a mechanism for angina pectoris in patients with arterial hypertension and normal coronary arteries. Circulation (1984) 1.23
A gene for universal congenital alopecia maps to chromosome 8p21-22. Am J Hum Genet (1998) 1.23
Metabolism of prostacyclin and 6-keto-prostaglandin F1 alpha in man. J Biol Chem (1980) 1.21
Intracellular compartmentation of troponin T: release kinetics after global ischemia and calcium paradox in the isolated perfused rat heart. J Mol Cell Cardiol (1995) 1.21
Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis. Circulation (2000) 1.21
Troponin T concentrations 72 hours after myocardial infarction as a serological estimate of infarct size. Heart (2002) 1.19
Influence of dipyridamol (Persantin) on myocardial adenosine metabolism. J Mol Cell Cardiol (1970) 1.18
Quantitative morphologic findings of the myocardium in idiopathic dilated cardiomyopathy. Am J Cardiol (1983) 1.16
HERG potassium channel activation is shifted by phorbol esters via protein kinase A-dependent pathways. J Biol Chem (1998) 1.16
Exercise and cytokines with particular focus on muscle-derived IL-6. Exerc Immunol Rev (2001) 1.16
Two novel mutations in the GDAP1 and PRX genes in early onset Charcot-Marie-Tooth syndrome. Neuropediatrics (2008) 1.15
Myocardial perfusion and regression of coronary artery disease in patients on a regimen of intensive physical exercise and low fat diet. J Am Coll Cardiol (1992) 1.15
Ventricular arrhythmias in idiopathic dilated cardiomyopathy. Br Heart J (1984) 1.14