Published in Bioorg Med Chem Lett on September 18, 2000
Fluoro-Sorafenib (Regorafenib) effects on hepatoma cells: growth inhibition, quiescence, and recovery. J Cell Physiol (2013) 1.14
Allosteric IGF-1R Inhibitors. ACS Med Chem Lett (2010) 0.85
Biological targets for therapeutic interventions in COPD: clinical potential. Int J Chron Obstruct Pulmon Dis (2006) 0.75
THE MEASUREMENT OF SYMPATHETIC VASOCONSTRICTOR ACTIVITY IN THE LOWER EXTREMITIES. J Clin Invest (1930) 32.02
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell (1987) 14.62
Fingerprinting Candida albicans. J Immunol Methods (1986) 6.90
Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40. Nature (1987) 6.76
Beyond randomized controlled trials: organized mammographic screening substantially reduces breast carcinoma mortality. Cancer (2001) 6.16
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell (1991) 6.14
Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol Cell Biol (1987) 5.67
Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo. J Biol Chem (1997) 5.14
Customized growth curves for identification of large-for-gestational age neonates in pre-eclamptic women. Ultrasound Obstet Gynecol (2014) 4.86
Overlapping genes at the cheA locus of Escherichia coli. Proc Natl Acad Sci U S A (1980) 4.82
Critical period effects in second language learning: the influence of maturational state on the acquisition of English as a second language. Cogn Psychol (1989) 4.27
The heat resistance of bacterial spores at various water activities. J Gen Microbiol (1966) 4.23
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen. J Biol Chem (1988) 4.06
A novel method for prediction of long-term outcome of women with T1a, T1b, and 10-14 mm invasive breast cancers: a prospective study. Lancet (2000) 3.76
Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein. J Biol Chem (1986) 3.67
Two classes of PDGF receptor recognize different isoforms of PDGF. Science (1988) 3.59
Evaluation of a polymerase chain reaction for the diagnosis of tuberculosis. Tubercle (1991) 3.58
The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors. Genes Dev (1991) 3.33
Efficacy of breast cancer screening by age. New results from the Swedish Two-County Trial. Cancer (1995) 3.32
Biocompatible surfactants for water-in-fluorocarbon emulsions. Lab Chip (2008) 3.28
Epithelial sodium channel regulated by aldosterone-induced protein sgk. Proc Natl Acad Sci U S A (1999) 3.19
The Swedish Two-County Trial twenty years later. Updated mortality results and new insights from long-term follow-up. Radiol Clin North Am (2000) 3.18
Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. J Biol Chem (2000) 3.12
Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF. EMBO J (1993) 3.11
Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device. AJNR Am J Neuroradiol (2010) 3.08
Association between culturable human immunodeficiency virus type 1 (HIV-1) in semen and HIV-1 RNA levels in semen and blood: evidence for compartmentalization of HIV-1 between semen and blood. J Infect Dis (1998) 2.98
Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4. J Exp Med (1985) 2.92
American Cancer Society guidelines for screening and surveillance for early detection of colorectal polyps and cancer: update 1997. American Cancer Society Detection and Treatment Advisory Group on Colorectal Cancer. CA Cancer J Clin (1997) 2.89
Outbreak of systemic Candida albicans in intensive care unit caused by cross infection. Br Med J (Clin Res Ed) (1985) 2.74
Genomic 5-methyldeoxycytidine decreases with age. J Biol Chem (1987) 2.74
Penicillin-resistant Streptococcus pneumoniae in acute otitis media: risk factors, susceptibility patterns and antimicrobial management. Pediatr Infect Dis J (1995) 2.73
Fibrinolysis with acyl-enzymes: a new approach to thrombolytic therapy. Nature (1981) 2.71
Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development. J Clin Invest (1990) 2.56
Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J Immunol (1991) 2.52
Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin Pharmacol Ther (2007) 2.52
A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature (2001) 2.50
Physician-performed point-of-care echocardiography using a laptop platform compared with physical examination in the cardiovascular patient. J Am Coll Cardiol (2001) 2.47
Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells. Nat Med (2001) 2.47
Worldwide esophageal cancer collaboration. Dis Esophagus (2009) 2.41
Increasing physician productivity and the hospitalization characteristics of practices using Medex. A progress report. Northwest Med (1971) 2.34
Quantifying the potential problem of overdiagnosis of ductal carcinoma in situ in breast cancer screening. Eur J Cancer (2003) 2.26
Treatment of pseudobulbar affect in ALS with dextromethorphan/quinidine: a randomized trial. Neurology (2004) 2.26
The broad spectrum antiviral agent ribavirin inhibits capping of mRNA. Biochem Biophys Res Commun (1979) 2.26
Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proc Natl Acad Sci U S A (1989) 2.26
The relative contributions of screen-detected in situ and invasive breast carcinomas in reducing mortality from the disease. Eur J Cancer (2003) 2.24
Benefit of screening mammography in women aged 40-49: a new meta-analysis of randomized controlled trials. J Natl Cancer Inst Monogr (1997) 2.24
Probing proton dynamics in molecules on an attosecond time scale. Science (2006) 2.24
Lymphedema: current issues in research and management. CA Cancer J Clin (2000) 2.21
Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. Genome Res (1997) 2.17
Pressure support ventilation decreases inspiratory work of breathing during general anesthesia and spontaneous ventilation. Anesth Analg (1992) 2.14
Benefit of mammography screening in women ages 40 to 49 years. Current evidence from randomized controlled trials. Cancer (1995) 2.13
Biological properties of a CD4 immunoadhesin. Nature (1990) 2.05
Bone marrow NK1.1(-) and NK1.1(+) T cells reciprocally regulate acute graft versus host disease. J Exp Med (1999) 2.00
Ribonucleic acid-protein fractions of virulent Salmonella typhimurium as protective immunogens. Infect Immun (1972) 1.99
A study guided by the Health Belief Model of the predictors of breast cancer screening of women ages 40 and older. Public Health Rep (1991) 1.97
Imidotitanium complexes as hydroamination catalysts: substantially enhanced reactivity from an unexpected cyclopentadienide/amide ligand exchange. J Am Chem Soc (2001) 1.90
Determination of inorganic phosphate in the presence of labile organic phosphates. Anal Biochem (1969) 1.89
The active form of tumor necrosis factor is a trimer. J Biol Chem (1987) 1.86
Comparative roles of the Arg-Gly-Asp sequence present in the Bordetella pertussis adhesins pertactin and filamentous hemagglutinin. Infect Immun (1992) 1.85
Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res (1996) 1.84
STUDIES ON THE ACTIVITY OF THE LUMBAR SYMPATHETIC NERVOUS SYSTEM. Ann Surg (1930) 1.83
Planning for the future: the experience of implementing a children's day assessment unit in a district general hospital. Arch Dis Child (1997) 1.83
Drug delivery to mitochondria: the key to mitochondrial medicine. Adv Drug Deliv Rev (2000) 1.82
Engineering a Bacillus subtilis expression-secretion system with a strain deficient in six extracellular proteases. J Bacteriol (1991) 1.82
Nature of glomerular dysfunction in pre-eclampsia. Kidney Int (1998) 1.81
The pressure reversal of general anesthesia and the critical volume hypothesis. Mol Pharmacol (1973) 1.79
A whole-genome radiation hybrid panel for bovine gene mapping. Mamm Genome (1997) 1.77
Twenty-year follow-up of the breast cancers diagnosed during the Breast Cancer Detection Demonstration Project. CA Cancer J Clin (1997) 1.75
Production of cytotoxic factor in the spleen of dengue virus-infected mice. Immunology (1980) 1.73
Intranasal Teeth. Report of two cases and review of the literature. Oral Surg Oral Med Oral Pathol (1979) 1.73
Pre- and postnatal choline supplementation produces long-term facilitation of spatial memory. Dev Psychobiol (1988) 1.72
Central hemodynamic assessment of normal term pregnancy. Am J Obstet Gynecol (1989) 1.71
Polyphosphate elicits pro-inflammatory responses that are counteracted by activated protein C in both cellular and animal models. J Thromb Haemost (2012) 1.71
Spontaneous release of interleukin 1 from human blood monocytes reflects bone formation in idiopathic osteoporosis. Proc Natl Acad Sci U S A (1987) 1.70
Effect of cyclophosphamide upon the immune response in Wegener's granulomatosis. N Engl J Med (1971) 1.70
Comparing the quality of death for hospice and non-hospice cancer patients. Med Care (1988) 1.67
Hemodynamic and gas exchange alterations during Intralipid infusion in patients with adult respiratory distress syndrome. Chest (1989) 1.66
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures. Am J Physiol (1999) 1.66
Practice guidelines for performance of the routine mid-trimester fetal ultrasound scan. Ultrasound Obstet Gynecol (2011) 1.66
Antitumor activity of sorafenib in FLT3-driven leukemic cells. Leukemia (2007) 1.65
Breast cancer diagnosis by screening mammography: early results of the Central Sydney Area Health Service Breast X-ray Programme. Med J Aust (1991) 1.64
PUBLIC HEALTH ENGINEERING: SURVEY OF CONNECTICUT'S SHORE BATHING WATERS. Am J Public Health Nations Health (1932) 1.64
Detection of delayed hypersensitivity in mice injected with ribonucleic acid-protein fractions of Salmonella typhimurium. Infect Immun (1972) 1.64
Methionine synthesis from 5'-methylthioadenosine in rat liver. J Biol Chem (1981) 1.63
Rheumatoid factor-producing cells detected by direct hemolytic plaque assay. J Clin Invest (1976) 1.62
Expression of calf prochymosin in Saccharomyces cerevisiae. Gene (1984) 1.61
Complement fixation by rheumatoid factor. J Clin Invest (1975) 1.60
Use of aminotransferase, hepatitis C antibody, and hepatitis C polymerase chain reaction RNA assays to establish the diagnosis of hepatitis C virus infection in a diagnostic virology laboratory. J Clin Microbiol (1992) 1.59
Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence. Br J Pharmacol (2010) 1.59
Altered lymphocyte reactivity in rheumatoid arthritis. Arthritis Rheum (1976) 1.58
Heterologous protein secretion from yeast. Science (1985) 1.58
CHANGES IN THE VASOMOTOR REACTION ASSOCIATED WITH GLOMUS TUMORS. J Clin Invest (1937) 1.57
Synthesis, characterization, and structure-activity relationships of amidine-substituted (bis)benzylidene-cycloketone olefin isomers as potent and selective factor Xa inhibitors. J Med Chem (1999) 1.56
Expression cloning and signaling properties of the rat glucagon receptor. Science (1993) 1.54
Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo. Cancer Res (1986) 1.54
SGK integrates insulin and mineralocorticoid regulation of epithelial sodium transport. Am J Physiol Renal Physiol (2001) 1.54
Physicochemical approaches to the mode of action of general anesthetics. Anesthesiology (1972) 1.53
Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis. Arthritis Rheum (1973) 1.53
Simulated workplace protection factor study of powered air-purifying and supplied air respirators. AIHAJ (2001) 1.52