Dipeptidyl carboxypeptidase 1 (DCP1) and butyrylcholinesterase (BCHE) gene interactions with the apolipoprotein E epsilon4 allele as risk factors in Alzheimer's disease and in Parkinson's disease with coexisting Alzheimer pathology.

PubWeight™: 0.85‹?›

🔗 View Article (PMC 1757160)

Published in J Med Genet on October 01, 2000

Authors

K M Mattila1, J O Rinne, M Röyttä, P Laippala, T Pietilä, H Kalimo, T Koivula, H Frey, T Lehtimäki

Author Affiliations

1: Department of Clinical Chemistry, Centre for Laboratory Medicine, Tampere University Hospital, Finn-Medi 2, Third Floor, PO Box 2000, FIN-33521 Tampere, Finland. klkama@uta.fi

Articles cited by this

Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology (1984) 119.59

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology (1991) 23.01

Genetic associations with human longevity at the APOE and ACE loci. Nat Genet (1994) 4.17

Human apolipoprotein E: the Alzheimer's disease connection. FASEB J (1996) 1.78

K variant of butyrycholinesterase and late-onset Alzheimer's disease. Lancet (1998) 1.52

Butyrylcholinesterase in the life cycle of amyloid plaques. Ann Neurol (1997) 1.27

Molecular genetics of Alzheimer's disease. Ann Med (1998) 1.25

Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nat Genet (1999) 1.22

Synergy between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset confirmed Alzheimer's disease. Hum Mol Genet (1997) 1.06

Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia. Ann Neurol (1994) 1.01

DNA polymorphisms of apolipoprotein B and angiotensin I-converting enzyme genes and relationships with lipid levels in Italian patients with vascular dementia or Alzheimer's disease. Dement Geriatr Cogn Disord (1998) 0.96

Detection of the plasma cholinesterase K variant by PCR using an amplification-created restriction site. Hum Hered (1996) 0.90

ACE, MTHFR, factor V Leiden, and APOE polymorphisms in patients with vascular and Alzheimer's dementia. Stroke (1998) 0.90

Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease. Hum Mol Genet (1998) 0.90

No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease. Hum Mol Genet (1998) 0.88

Further evidence for a synergistic association between APOE epsilon4 and BCHE-K in confirmed Alzheimer's disease. Hum Genet (1999) 0.87

Angiotensin converting enzyme and endothelial nitric oxide synthase DNA polymorphisms and late onset Alzheimer's disease. J Neurol Neurosurg Psychiatry (1999) 0.87

The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease. J Med Genet (1998) 0.87

Angiotensin converting enzyme deletion allele in different kinds of dementia disorders. Neurosci Lett (1999) 0.87

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease. Eur J Hum Genet (1999) 0.85

Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients. Neurosci Lett (1998) 0.84

Rapid apolipoprotein E genotyping from mailed buccal swabs. J Neurosci Methods (1998) 0.84

Mistyping frequency of the angiotensin-converting enzyme gene polymorphism and an improved method for its avoidance. Hum Genet (1997) 0.83

Genetic polymorphisms in Parkinson's disease. Neurotoxicology (1998) 0.82

The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations. Neurosci Lett (1998) 0.82

Butyrycholinesterase K variant and Alzheimer's disease. J Neurol (1999) 0.81

No association between the genes for butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer's disease. Am J Med Genet (1999) 0.81

Analysis of association between Alzheimer disease and the K variant of butyrylcholinesterase (BCHE-K). Neurosci Lett (1999) 0.81

Apolipoprotein E epsilon4 allele frequency is increased in Parkinson's disease only with co-existing Alzheimer pathology. Acta Neuropathol (1998) 0.80

Failure to confirm a synergistic effect between the K-variant of the butyrylcholinesterase gene and the epsilon4 allele of the apolipoprotein gene in Japanese patients with Alzheimer's disease. J Neurol Neurosurg Psychiatry (1999) 0.80

The ACE deletion polymorphism is not associated with Parkinson's disease. Eur Neurol (1999) 0.79

Association between butyrylcholinesterase K variant and the Alzheimer type neuropathological changes in apolipoprotein E epsilon4 carriers older than 75 years. J Neurol Neurosurg Psychiatry (1999) 0.78

The genetics of Parkinson's disease and parkinsonian syndromes. J Neurol (1998) 0.78

Butyrylcholinesterase K: an association with dementia with Lewy bodies. Lancet (1998) 0.78

Genetics of Parkinson's disease. Biomed Pharmacother (1999) 0.77

Articles by these authors

Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study. Neurology (2009) 3.49

The state and fate of Himalayan glaciers. Science (2012) 3.33

Coeliac disease--associated disorders and survival. Gut (1994) 3.13

Spread of drug-resistant pulmonary tuberculosis in Estonia. J Clin Microbiol (2001) 3.12

Heavy-load eccentric calf muscle training for the treatment of chronic Achilles tendinosis. Am J Sports Med (1998) 3.09

Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release (2000) 3.07

Balance board training: prevention of traumatic injuries of the lower extremities in female soccer players? A prospective randomized intervention study. Knee Surg Sports Traumatol Arthrosc (2000) 2.91

The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry (1998) 2.88

Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine. Lancet (2002) 2.65

PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment. Neurology (2007) 2.63

Risk factors for leg injuries in female soccer players: a prospective investigation during one out-door season. Knee Surg Sports Traumatol Arthrosc (2001) 2.50

Reference intervals developed from data for hospitalized patients: computerized method based on combination of laboratory and diagnostic data. Clin Chem (1994) 2.31

A human Lactobacillus strain (Lactobacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics (1991) 2.30

Follow-up of [11C]PIB uptake and brain volume in patients with Alzheimer disease and controls. Neurology (2009) 2.27

Neuritic transport of herpes simplex virus in rat sensory neurons in vitro. Effects of substances interacting with microtubular function and axonal flow [nocodazole, taxol and erythro-9-3-(2-hydroxynonyl)adenine]. J Gen Virol (1986) 2.24

Evolution and clonal traits of Mycobacterium tuberculosis complex in Guinea-Bissau. J Clin Microbiol (1999) 2.23

A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1. Nat Med (1998) 2.20

Longitudinal study of maternal depressive symptoms and child well-being. J Am Acad Child Adolesc Psychiatry (2001) 2.18

Real-time elastography--an advanced method of ultrasound: First results in 108 patients with breast lesions. Ultrasound Obstet Gynecol (2006) 2.12

Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. J Neurol Neurosurg Psychiatry (2008) 2.12

Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population. Ann Med (1995) 1.97

Interstitial chemotherapy with carmustine-loaded polymers for high-grade gliomas: a randomized double-blind study. Neurosurgery (1997) 1.97

Association of c-erbB-2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer. Int J Cancer (1991) 1.85

Voxel-based analysis of PET amyloid ligand [11C]PIB uptake in Alzheimer disease. Neurology (2006) 1.85

When do social inequalities in C-reactive protein start? A life course perspective from conception to adulthood in the Cardiovascular Risk in Young Finns Study. Int J Epidemiol (2007) 1.74

The lumbar multifidus muscle five years after surgery for a lumbar intervertebral disc herniation. Spine (Phila Pa 1976) (1993) 1.73

Effect of work with visual display units on musculo-skeletal disorders in the office environment. Occup Med (Lond) (2003) 1.71

Treatment of psoriasis with bromocriptin. Arch Dermatol Res (1981) 1.70

Hereditary diffuse leucoencephalopathy with spheroids. Acta Psychiatr Scand Suppl (1984) 1.68

CCR5 genotype and resistance to vertical transmission of HIV-1. J Acquir Immune Defic Syndr (1999) 1.67

Brain lactic acidosis and ischemic cell damage: 2. Histopathology. J Cereb Blood Flow Metab (1981) 1.66

Satellite cell proliferation and the expression of myogenin and desmin in regenerating skeletal muscle: evidence for two different populations of satellite cells. Lab Invest (1995) 1.62

Moderate and heavy alcohol consumption have no favorable effect on lipid values. Arch Intern Med (1992) 1.61

Incidence of disorders of spermatogenesis in middle aged finnish men, 1981-91: two necropsy series. BMJ (1997) 1.60

Incidence, nature, and causes of ice hockey injuries. A three-year prospective study of a Swedish elite ice hockey team. Am J Sports Med (1988) 1.58

Hypoglycemic brain injury. I. Metabolic and light microscopic findings in rat cerebral cortex during profound insulin-induced hypoglycemia and in the recovery period following glucose administration. Acta Neuropathol (1980) 1.56

Validity of clinical diagnosis in dementia: a prospective clinicopathological study. J Neurol Neurosurg Psychiatry (1985) 1.54

Moderate alcohol consumption and loss of cerebellar Purkinje cells. BMJ (1994) 1.53

Death rates and causes of death in patients with rheumatoid arthritis: a population-based study. Scand J Rheumatol (2004) 1.53

Renal disease as a predictor of increased mortality among patients with rheumatoid arthritis. Nephron Clin Pract (2004) 1.52

Physiological factors and medications as predictors of injurious falls by elderly people: a prospective population-based study. Age Ageing (1996) 1.52

Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. Nat Genet (1998) 1.52

CSF and MRI findings in patients with acute herpes zoster. Neurology (1998) 1.49

In vivo mapping of amyloid toxicity in Alzheimer disease. Neurology (2009) 1.47

Aneuploid DNA content and high S-phase fraction of tumour cells are related to poor prognosis in patients with primary breast cancer. Eur J Cancer Clin Oncol (1987) 1.46

Intraepithelial gamma delta T-cell-receptor lymphocytes and genetic susceptibility to coeliac disease. Lancet (1992) 1.45

Disability pensions in severely disturbed in-patient adolescents. Twenty-year prospective study. Br J Psychiatry (1998) 1.44

Intracranial aneurysms in three patients with disseminated Lyme borreliosis: cause or chance association? J Neurol Neurosurg Psychiatry (1998) 1.44

Altered blood-brain-barrier function in Alzheimer's disease? Acta Neurol Scand (1994) 1.44

Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis. Clin Chem (1999) 1.43

Rapid identification of angiotensin-converting enzyme genotypes by capillary electrophoresis. Clin Chem (1997) 1.43

Alpha-synuclein-immunoreactive cortical Lewy bodies are associated with cognitive impairment in Parkinson's disease. Acta Neuropathol (2000) 1.41

Improving the prognostic value of DNA flow cytometry in breast cancer by combining DNA index and S-phase fraction. A proposed classification of DNA histograms in breast cancer. Cancer (1988) 1.40

PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment. Dement Geriatr Cogn Disord (2008) 1.39

Sex differences in the striatal dopamine D2 receptor binding characteristics in vivo. Am J Psychiatry (1998) 1.39

Visual neglect as a predictor of functional outcome one year after stroke. Acta Neurol Scand (2000) 1.38

[Assessment of the information gathered during basic medical education]. Duodecim (2000) 1.38

Role of the dopaminergic system in chronic pain -- a fluorodopa-PET study. Pain (2001) 1.37

Small subgroup of aggressive, highly proliferative prostatic carcinomas defined by p53 accumulation. J Natl Cancer Inst (1992) 1.36

Depressive symptoms and the risk of sudden cardiac death among the elderly. Eur Heart J (2003) 1.36

Regulated expression of exon v6 containing isoforms of CD44 in man: downregulation during malignant transformation of tumors of squamocellular origin. J Cell Biol (1993) 1.34

Leber's hereditary optic neuroretinopathy, a mitochondrial disease? Lancet (1984) 1.34

PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain (2008) 1.34

Effects of severe hypoglycemia on the human brain. Neuropathological case reports. Acta Neurol Scand (1980) 1.34

Treatment of psoriasis with somatostatin. Arch Dermatol Res (1982) 1.31

Predictors for recurrent falls among the home-dwelling elderly. Scand J Prim Health Care (1995) 1.31

Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Nat Genet (2001) 1.31

Longitudinal stability of CSF tau levels in Alzheimer patients. Biol Psychiatry (1999) 1.30

Mycobacterium tuberculosis Uganda genotype is the predominant cause of TB in Kampala, Uganda. Int J Tuberc Lung Dis (2008) 1.30

Gene deletions in X-linked muscular dystrophy. Am J Hum Genet (1989) 1.29

Surgery vs orthosis vs watchful waiting for hallux valgus: a randomized controlled trial. JAMA (2001) 1.27

Prognosis of diastolic and systolic orthostatic hypotension in older persons. Arch Intern Med (1999) 1.27

The temporal evolution of hypoglycemic brain damage. I. Light- and electron-microscopic findings in the rat cerebral cortex. Acta Neuropathol (1985) 1.26

Amyloid PET imaging in patients with mild cognitive impairment: a 2-year follow-up study. Neurology (2011) 1.26

Maternal compared with infant vitamin D supplementation. Arch Dis Child (1986) 1.25

Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment. J Neurol Neurosurg Psychiatry (2004) 1.24

Hypoglycemic brain injury. II. Electron-microscopic findings in rat cerebral cortical neurons during profound insulin-induced hypoglycemia and in the recovery period following glucose administration. Acta Neuropathol (1980) 1.23

C957T polymorphism of the dopamine D2 receptor (DRD2) gene affects striatal DRD2 availability in vivo. Mol Psychiatry (2004) 1.23

A longitudinal cohort study of Finnish patients with primary Sjögren's syndrome: clinical, immunological, and epidemiological aspects. Ann Rheum Dis (2001) 1.22

Increased frontal [(18)F]fluorodopa uptake in early Parkinson's disease: sex differences in the prefrontal cortex. Brain (2001) 1.22

Relation between myofibers and connective tissue during muscle injury repair. Scand J Med Sci Sports (2000) 1.22

Baseline diene conjugation in LDL lipids as a direct measure of in vivo LDL oxidation. Clin Biochem (1998) 1.22

An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. Neurology (2000) 1.22

Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men: an autopsy study. Circulation (1999) 1.21

Paraoxonase gene polymorphisms and coronary reactivity in young healthy men. J Mol Med (Berl) (2001) 1.21

Identification of fibroblasts responsible for increased collagen production in localized scleroderma by in situ hybridization. J Invest Dermatol (1988) 1.21

Decreased interleukin-4 and increased gamma interferon production by peripheral blood mononuclear cells of patients with Lyme borreliosis. Infect Immun (1996) 1.20

Risk factors for major injurious falls among the home-dwelling elderly by functional abilities. A prospective population-based study. Gerontology (1998) 1.20

Taxol-induced neuropathy: short-term effects of local injection. J Neurocytol (1984) 1.19

Brain lactic acidosis and ischemic cell damage: quantitative ultrastructural changes in capillaries of rat cerebral cortex. Acta Neuropathol (1983) 1.19

Mitochondrial DNA polymorphism in Finnish families with Leber's hereditary optic neuroretinopathy. Hum Genet (1989) 1.18

Effect of an oats-containing gluten-free diet on symptoms and quality of life in coeliac disease. A randomized study. Scand J Gastroenterol (2004) 1.18

Tumour DNA ploidy as an independent prognostic factor in breast cancer. Br J Cancer (1987) 1.18

Tibial muscular dystrophy. Late adult-onset distal myopathy in 66 Finnish patients. Arch Neurol (1993) 1.18

Pain and somatosensory dysfunction in acute herpes zoster. Clin J Pain (1999) 1.17