PubRank

M Anai

Author PubWeight™ 69.97‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nonsense mutation of glucokinase gene in late-onset non-insulin-dependent diabetes mellitus. Lancet 1992 2.71
2 Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 1993 2.11
3 A novel 55-kDa regulatory subunit for phosphatidylinositol 3-kinase structurally similar to p55PIK Is generated by alternative splicing of the p85alpha gene. J Biol Chem 1996 1.47
4 Acetyl-CoA carboxylase from Escherichia coli: gene organization and nucleotide sequence of the biotin carboxylase subunit. Proc Natl Acad Sci U S A 1991 1.44
5 A deoxyribonuclease which requires nucleoside triphosphate from Micrococcus lysodeikticus. I. Purification and characterization of the deoxyribonuclease activity. J Biol Chem 1970 1.39
6 Epidemiologic investigation of the relative clearance of haloperidol by mixed-effect modeling using routine clinical pharmacokinetic data in Japanese patients. J Clin Psychopharmacol 2000 1.38
7 p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin. J Biol Chem 1997 1.37
8 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. J Biol Chem 1997 1.32
9 T-1095, an inhibitor of renal Na+-glucose cotransporters, may provide a novel approach to treating diabetes. Diabetes 1999 1.32
10 p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity. J Biol Chem 2000 1.24
11 Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction. Diabetes 2000 1.22
12 Positive and negative regulation of transcription by a cleavage product of Ada protein. J Mol Biol 1990 1.09
13 MKK6/3 and p38 MAPK pathway activation is not necessary for insulin-induced glucose uptake but regulates glucose transporter expression. J Biol Chem 2001 1.07
14 [Deoxyribonuclease requiring nucleoside triphosphate]. Seikagaku 1967 1.04
15 Cloning and increased expression with fructose feeding of rat jejunal GLUT5. Endocrinology 1993 1.04
16 Regulation of phosphoinositide metabolism, Akt phosphorylation, and glucose transport by PTEN (phosphatase and tensin homolog deleted on chromosome 10) in 3T3-L1 adipocytes. Mol Endocrinol 2001 1.03
17 Purification of small polydisperse circular DNA of eukaryotic cells by use of ATP-dependent deoxyribonuclease. Gene 1983 1.03
18 Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase. Diabetologia 2004 1.02
19 Multihormonal regulation of transcription of the tryptophan 2,3-dioxygenase gene in primary cultures of adult rat hepatocytes with special reference to the presence of a transcriptional protein mediating the action of glucocorticoids. J Biol Chem 1987 1.02
20 The role of N-glycosylation in the targeting and stability of GLUT1 glucose transporter. FEBS Lett 1993 1.01
21 Hyperglycemia contributes insulin resistance in hepatic and adipose tissue but not skeletal muscle of ZDF rats. Am J Physiol Endocrinol Metab 2000 0.99
22 Insulin receptor substrate (IRS)-2 is dephosphorylated more rapidly than IRS-1 via its association with phosphatidylinositol 3-kinase in skeletal muscle cells. J Biol Chem 1997 0.99
23 A deoxyribonuclease which requires nucleoside triphosphate from Micrococcus lysodeikticus. II. Studies on the role of nucleoside triphosphate. J Biol Chem 1970 0.98
24 Nuclear location of the regulatory protein of glucokinase in rat liver and translocation of the regulator to the cytoplasm in response to high glucose. Biochem Biophys Res Commun 1995 0.98
25 Properties of the recB and recC gene products of Escherichia coli. Biochem Biophys Res Commun 1983 0.97
26 No correlation of plasma cell 1 overexpression with insulin resistance in diabetic rats and 3T3-L1 adipocytes. Diabetes 1999 0.97
27 Purification and properties of an endodeoxyribonuclease from nuclei of bovine small intestinal mucosa. J Biol Chem 1981 0.97
28 Serum concentrations of resistin-like molecules beta and gamma are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tract and bone marrow. Diabetologia 2005 0.97
29 The pyridoxal phosphate-binding site of rabbit muscle aldolase. Arch Biochem Biophys 1973 0.96
30 Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations. FEBS Lett 2001 0.96
31 Degradation of deoxyribonucleic acid by guinea pig epidermal extracts. Arch Dermatol Res 1975 0.95
32 A novel isoform of syntaxin-binding protein homologous to yeast Sec1 expressed ubiquitously in mammalian cells. J Biol Chem 1995 0.93
33 The N-terminal 34 residues of the 55 kDa regulatory subunits of phosphoinositide 3-kinase interact with tubulin. Biochem J 2000 0.92
34 Replacement of both tryptophan residues at 388 and 412 completely abolished cytochalasin B photolabelling of the GLUT1 glucose transporter. Biochem J 1994 0.92
35 Potent and long-lasting action of lafutidine on the human histamine H(2) receptor. Digestion 2001 0.92
36 Insulin resistance with enhanced insulin signaling in high-salt diet-fed rats. Diabetes 2001 0.91
37 Imidapril, an angiotensin-converting enzyme inhibitor, improves insulin sensitivity by enhancing signal transduction via insulin receptor substrate proteins and improving vascular resistance in the Zucker fatty rat. Metabolism 1999 0.91
38 Overexpression of hexokinase I but not GLUT1 glucose transporter alters concentration dependence of glucose-stimulated insulin secretion in pancreatic beta-cell line MIN6. J Biol Chem 1994 0.90
39 An endonuclease associated with bovine plasma albumin fraction. II. The origin and activation mechanism of the enzyme. J Biol Chem 1972 0.89
40 Palmitoylation of the canine histamine H2 receptor occurs at Cys(305) and is important for cell surface targeting. Biochim Biophys Acta 2001 0.89
41 Multiple isoforms of the regulatory subunit for phosphatidylinositol 3-kinase (PI3-kinase) are expressed in neurons in the rat brain. Biochem Biophys Res Commun 1998 0.88
42 Characterization of rat GLUT5 and functional analysis of chimeric proteins of GLUT1 glucose transporter and GLUT5 fructose transporter. Endocrinology 1995 0.88
43 Hyperglycemia impairs the insulin signaling step between PI 3-kinase and Akt/PKB activations in ZDF rat liver. Biochem Biophys Res Commun 1999 0.88
44 A deoxyribonuclease which requires nucleoside triphosphate from Micrococcus lysodeikticus. IV. The mode of DNA hydrolysis. Biochim Biophys Acta 1972 0.87
45 Regulatory elements for expression of the alkA gene in response to alkylating agents. Mol Gen Genet 1992 0.87
46 Antidiabetic effect of T-1095, an inhibitor of Na(+)-glucose cotransporter, in neonatally streptozotocin-treated rats. Eur J Pharmacol 2000 0.86
47 Purification and properties of acid deoxyribonucleases of human gastric mucosa and cervix uteri. J Biol Chem 1974 0.84
48 Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle. Am J Physiol Endocrinol Metab 2001 0.84
49 Purification and properties of deoxyribonuclease from human urine. Biochim Biophys Acta 1978 0.84
50 Clinical relevance of heteroplasmic concentration of mitochondrial A3243G mutation in leucocytes. Diabetologia 1999 0.83
51 A synthetic peptide deduced from the sequence in the cross-region of laminin A chain mediates neurite outgrowth, cell attachment and heparin binding. Biochem J 1994 0.82
52 Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells. Gut 2002 0.81
53 Interaction between the two signal transduction systems of the histamine H2 receptor: desensitizing and sensitizing effects of histamine stimulation on histamine-dependent cAMP production in Chinese hamster ovary cells. Biochem J 1996 0.81
54 Role of the C terminus in histamine H2 receptor signaling, desensitization, and agonist-induced internalization. J Biol Chem 1997 0.81
55 Purification and characterization of two components of acid alpha-glucosidase from pig liver. J Biochem 1986 0.81
56 p85/p110-type phosphatidylinositol kinase phosphorylates not only the D-3, but also the D-4 position of the inositol ring. J Biol Chem 1999 0.81
57 Purification and subunit structure of recBC DNase from Escherichia coli harboring a recB and recC genes-inserted plasmid. J Biochem 1985 0.80
58 The structure of glycopeptide obtained from Taka-amylase A. J Biochem 1966 0.79
59 Purification and characterization of guinea-pig epidermal acid phosphatase. Br J Dermatol 1977 0.78
60 Purification and properties of a neutral endodeoxyribonuclease from guinea pig epidermis. Biochim Biophys Acta 1981 0.77
61 Two pH optima of adenosine 5'-triphosphate dependent deoxyribonuclease from Bacillus laterosporus. Biochemistry 1982 0.77
62 Role of JTT-501, a new insulin sensitiser, in restoring impaired GLUT4 translocation in adipocytes of rats fed a high fat diet. Diabetologia 1998 0.77
63 A deoxyribonuclease which requires nucleoside triphosphate from Micrococcus lysodeikticus. Exchange reaction catalyzed by the enzyme preparation. J Biol Chem 1971 0.77
64 Purification and properties of deoxyribonuclease II from human urine. J Biochem 1980 0.76
65 Human GLUT-2 overexpression does not affect glucose-stimulated insulin secretion in MIN6 cells. Am J Physiol 1995 0.76
66 Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells. FEBS Lett 1997 0.76
67 Inhibition of the recBC enzyme of Escherichia coli by specific binding of pyridoxal 5'-phosphate to DNA binding site. J Biol Chem 1979 0.76
68 Mitochondrial diabetes mellitus: prevalence and clinical characterization of diabetes due to mitochondrial tRNA(Leu(UUR)) gene mutation in Japanese patients. Diabetologia 1994 0.76
69 G649, an allelic variant of the human H2 receptor with low basal activity, is resistant to upregulation upon antagonist exposure. Pharmacogenomics J 2001 0.75
70 Localization of the histamine H(2) receptor, a target for antiulcer drugs, in gastric parietal cells. Digestion 2000 0.75
71 Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein. Biochem Biophys Res Commun 2001 0.75
72 Purification and properties of a neutral endodeoxyribonuclease from rat small intestinal mucosa. Biochemistry 1982 0.75
73 Inactivation of ATP-dependent deoxyribonuclease of Micrococcus luteus by 2,3-butanedione. J Biochem 1982 0.75
74 [Reproductive and developmental toxicity study of suplatast tosilate (IPD-1151T) (4)--Perinatal and postnatal study in rats by oral administration]. J Toxicol Sci 1992 0.75
75 [Single-dose toxicity studies of tazobactam/piperacillin and tazobactam]. J Toxicol Sci 1994 0.75
76 Purification and properties of adenosine 5'-triphosphate-dependent deoxyribonuclease from Thermus thermophilus HB8. J Biochem 1983 0.75
77 Inhibitory effect of pyridoxal 5'-phosphate on the DNA binding site of ATP-dependent deoxyribonuclease from Bacillus laterosporus. J Biochem 1981 0.75
78 A nucleoside triphosphate-dependent deoxyribonuclease from Bacillus laterosporus. Purification and characterization of the enzyme. J Biochem 1975 0.75
79 Interindividual variation of serum haloperidol concentrations in Japanese patients--clinical considerations on steady-state serum level-dose ratios. J Clin Pharm Ther 2003 0.75
80 An endonuclease associated with bovine plasma albumin fraction. A purification and some properties of the enzyme. J Biol Chem 1972 0.75
81 Effects on growth of rat offspring born from dams treated subcutaneously with a surfactant, polyoxyethylene(10)nonylphenyl ether(NP-10), during lactational period. J Toxicol Sci 1999 0.75
82 Inhibitory effect of bovine serum albumin on acid deoxyribonuclease from rat small intestinal mucosa. J Biochem 1983 0.75
83 Purification and properties of an acid deoxyribonuclease from rat small intestinal mucosa. J Biochem 1983 0.75
84 An adenosine triphosphate-dependent deoxyribonuclease from Bacillus laterosporus. Improved purification, subunit structure and substrate specificity. J Biochem 1981 0.75
85 A nucleoside triphosphate-dependent deoxyribonuclease from Bacillus laterosporus. The mode of action of the enzyme. J Biochem 1975 0.75
86 [Polynucleotide ligase: reaction mechanisms and their physiological role]. Tanpakushitsu Kakusan Koso 1968 0.75
87 Endodeoxyribonuclease from nuclei of bovine small intestinal mucosa: further studies on intranuclear localization and cleavage mechanism of the enzyme. Biochem Biophys Res Commun 1983 0.75