Published in Microbiology on October 01, 2000
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J (2003) 5.78
Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest (2003) 2.54
gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication. Appl Environ Microbiol (2001) 2.50
Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. Antimicrob Agents Chemother (2001) 2.11
Distribution, organization, and ecology of bacteria in chronic wounds. J Clin Microbiol (2008) 2.05
Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere. Appl Environ Microbiol (2001) 1.86
Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2001) 1.86
Pseudomonas aeruginosa quorum-sensing systems may control virulence factor expression in the lungs of patients with cystic fibrosis. Infect Immun (2002) 1.85
Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice. Antimicrob Agents Chemother (2007) 1.71
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens. Philos Trans R Soc Lond B Biol Sci (2007) 1.70
Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis. Infect Immun (2005) 1.69
Where microbiology meets microengineering: design and applications of reporter bacteria. Nat Rev Microbiol (2010) 1.66
Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia. Proc Natl Acad Sci U S A (2004) 1.66
Spatial-temporal imaging of bacterial infection and antibiotic response in intact animals. Proc Natl Acad Sci U S A (2001) 1.59
Characterization of cell-to-cell signaling-deficient Pseudomonas aeruginosa strains colonizing intubated patients. J Clin Microbiol (2004) 1.40
N-acylhomoserine lactones involved in quorum sensing control the type VI secretion system, biofilm formation, protease production, and in vivo virulence in a clinical isolate of Aeromonas hydrophila. Microbiology (2009) 1.38
Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules. Infect Immun (2004) 1.25
Quorum size of Pseudomonas syringae is small and dictated by water availability on the leaf surface. Proc Natl Acad Sci U S A (2008) 1.21
Pharmacokinetics/pharmacodynamics of colistin and imipenem on mucoid and nonmucoid Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2011) 1.10
The transcriptional regulator AlgR is essential for Pseudomonas aeruginosa pathogenesis. Infect Immun (2002) 1.10
In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection. Antimicrob Agents Chemother (2012) 1.06
Two dissimilar N-acyl-homoserine lactone acylases of Pseudomonas syringae influence colony and biofilm morphology. Appl Environ Microbiol (2008) 1.01
In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect. Nat Protoc (2010) 0.97
DNA microarrays in analysis of quorum sensing: strengths and limitations. J Bacteriol (2003) 0.96
Bench-to-bedside review: Quorum sensing and the role of cell-to-cell communication during invasive bacterial infection. Crit Care (2008) 0.95
High β-lactamase levels change the pharmacodynamics of β-lactam antibiotics in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother (2012) 0.95
Staphylococcus aureus elicits marked alterations in the airway proteome during early pneumonia. Infect Immun (2008) 0.93
Construction of self-transmissible green fluorescent protein-based biosensor plasmids and their use for identification of N-acyl homoserine-producing bacteria in lake sediments. Appl Environ Microbiol (2010) 0.83
In vivo evaluation of adeno-associated virus gene transfer in airways of mice with acute or chronic respiratory infection. Hum Gene Ther (2014) 0.82
Development of an ex vivo porcine lung model for studying growth, virulence, and signaling of Pseudomonas aeruginosa. Infect Immun (2014) 0.82
Use of a whole-cell biosensor and flow cytometry to detect AHL production by an indigenous soil community during decomposition of litter. Microb Ecol (2005) 0.81
Cable pili and the associated 22 kDa adhesin contribute to Burkholderia cenocepacia persistence in vivo. PLoS One (2011) 0.80
Xanthomonas campestris cell-cell signalling molecule DSF (diffusible signal factor) elicits innate immunity in plants and is suppressed by the exopolysaccharide xanthan. J Exp Bot (2015) 0.79
Serum influences the expression of Pseudomonas aeruginosa quorum-sensing genes and QS-controlled virulence genes during early and late stages of growth. Microbiologyopen (2014) 0.77
Opportunities for applying whole-cell bioreporters towards parasite detection. Microb Biotechnol (2017) 0.75
Quantification of biofilm structures by the novel computer program COMSTAT. Microbiology (2000) 11.05
New unstable variants of green fluorescent protein for studies of transient gene expression in bacteria. Appl Environ Microbiol (1998) 6.61
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells. Proc Natl Acad Sci U S A (1986) 5.00
Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function. J Bacteriol (2001) 4.09
Low-copy-number plasmid-cloning vectors amplifiable by derepression of an inserted foreign promoter. Gene (1984) 4.03
Imaging membrane protein helical wheels. J Magn Reson (2000) 3.80
Involvement of N-acyl-L-hormoserine lactone autoinducers in controlling the multicellular behaviour of Serratia liquefaciens. Mol Microbiol (1996) 3.71
Molecular tools for study of biofilm physiology. Methods Enzymol (1999) 3.53
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties. Oncogene (2009) 3.51
Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling. J Bacteriol (1996) 3.47
Severity of cystic fibrosis in patients homozygous and heterozygous for delta F508 mutation. Lancet (1991) 3.37
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility. Microbiology (2001) 3.37
Pathogenesis of cystic fibrosis. Lancet (1993) 3.34
Prevention of chronic Pseudomonas aeruginosa colonisation in cystic fibrosis by early treatment. Lancet (1991) 3.26
Antibiotic treatment of initial colonization with Pseudomonas aeruginosa postpones chronic infection and prevents deterioration of pulmonary function in cystic fibrosis. Pediatr Pulmonol (1997) 3.23
Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus. Eur Respir J (2000) 3.14
Frequent antibiotic therapy improves survival of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection. Acta Paediatr Scand (1983) 3.13
Mucoid conversion of Pseudomonas aeruginosa by hydrogen peroxide: a mechanism for virulence activation in the cystic fibrosis lung. Microbiology (1999) 3.03
The anti-sigma factors. Annu Rev Microbiol (1998) 2.93
Distribution of bacterial growth activity in flow-chamber biofilms. Appl Environ Microbiol (1999) 2.83
In situ gene expression in mixed-culture biofilms: evidence of metabolic interactions between community members. Appl Environ Microbiol (1998) 2.82
Stable inheritance of plasmid R1 requires two different loci. J Bacteriol (1985) 2.78
Partitioning of plasmid R1 in Escherichia coli. I. Kinetics of loss of plasmid derivatives deleted of the par region. Plasmid (1980) 2.75
RNAs involved in copy-number control and incompatibility of plasmid R1. Proc Natl Acad Sci U S A (1981) 2.73
Development and dynamics of Pseudomonas sp. biofilms. J Bacteriol (2000) 2.72
Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria. Mol Microbiol (1999) 2.59
An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature (1994) 2.57
Improved survival in the Danish center-treated cystic fibrosis patients: results of aggressive treatment. Pediatr Pulmonol (1996) 2.55
Surface motility of serratia liquefaciens MG1. J Bacteriol (1999) 2.55
Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon. EMBO J (1986) 2.54
N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms. Microbiology (2001) 2.51
Control of replication of bacterial plasmids: genetics, molecular biology, and physiology of the plasmid R1 system. Plasmid (1984) 2.51
Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth. Microbes Infect (2001) 2.50
gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication. Appl Environ Microbiol (2001) 2.50
Assessment of GFP fluorescence in cells of Streptococcus gordonii under conditions of low pH and low oxygen concentration. Microbiology (2001) 2.47
Responses to nutrient starvation in Pseudomonas putida KT2442: analysis of general cross-protection, cell shape, and macromolecular content. J Bacteriol (1994) 2.46
An epidemic spread of multiresistant Pseudomonas aeruginosa in a cystic fibrosis centre. J Antimicrob Chemother (1986) 2.43
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41
Spatial distribution of Escherichia coli in the mouse large intestine inferred from rRNA in situ hybridization. Infect Immun (1994) 2.40
Site-specific deletions of chromosomally located DNA segments with the multimer resolution system of broad-host-range plasmid RP4. J Bacteriol (1995) 2.39
Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein. Microbiology (1999) 2.37
Endoscopic transhiatal drainage of a mediastinal pancreatic pseudocyst. Endoscopy (2004) 2.34
Simple downshift and resulting lack of correlation between ppGpp pool size and ribonucleic acid accumulation. J Bacteriol (1975) 2.34
N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1. J Bacteriol (1998) 2.32
Experimental reproducibility in flow-chamber biofilms. Microbiology (2000) 2.28
Establishment of new genetic traits in a microbial biofilm community. Appl Environ Microbiol (1998) 2.25
Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. J Clin Invest (1999) 2.24
Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease. Neurology (2012) 2.23
A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm. Environ Microbiol (2000) 2.22
Helix tilt of the M2 transmembrane peptide from influenza A virus: an intrinsic property. J Mol Biol (2000) 2.21
Physiological state of Escherichia coli BJ4 growing in the large intestines of streptomycin-treated mice. J Bacteriol (1995) 2.18
Induction of beta-lactamase production in Pseudomonas aeruginosa biofilm. Antimicrob Agents Chemother (1991) 2.09
Post-transcriptional control of expression of the repA gene of plasmid R1 mediated by a small RNA molecule. EMBO J (1983) 2.09
Differentiation of Serratia liquefaciens into swarm cells is controlled by the expression of the flhD master operon. J Bacteriol (1996) 2.08
Rapid emergence of resistance in Pseudomonas aeruginosa in cystic fibrosis patients due to in-vivo selection of stable partially derepressed beta-lactamase producing strains. J Antimicrob Chemother (1990) 2.08
Occurrence of a common lipopolysaccharide antigen in standard and clinical strains of Pseudomonas aeruginosa. J Clin Microbiol (1989) 2.07
Induction of phospholipase- and flagellar synthesis in Serratia liquefaciens is controlled by expression of the flagellar master operon flhD. Mol Microbiol (1995) 2.07