Published in Clin Pharmacol Ther on November 01, 1975
Relation between dose and levels of gentamicin in blood. J Infect Dis (1971) 4.29
Hypolipidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature (1980) 2.85
Activity of five aminoglycoside antibiotics in vitro against gram-negative bacilli and Staphylococcus aureus. Antimicrob Agents Chemother (1973) 2.85
In vitro studies of piperacilin, a new semisynthetic penicillin. Antimicrob Agents Chemother (1978) 2.82
Effect of environmental factors on drug metabolism: decreased plasma half-life of antipyrine in workers exposed to chlorinated hydrocarbon insecticides. Clin Pharmacol Ther (1969) 2.75
Arabinosyl cytosine: a useful agent in the treatment of acute leukemia in adults. Blood (1968) 2.71
Gentamicin blood levels: a guide to nephrotoxicity. Antimicrob Agents Chemother (1975) 2.48
Comparison of methods for assessing in vitro antibiotic synergism against Pseudomonas and Serratia. J Lab Clin Med (1975) 2.41
Radioimmunoassay, acetylating radio-enzymatic assay, and microbioassay of gentamicin: a comparative study. J Lab Clin Med (1975) 2.30
Response of hepatic microbodies to a hypolipidemic agent, ethyl chlorophenoxyisobutyrate (CPIB). J Cell Biol (1966) 2.29
Comparative in vitro activity of moxalactam, cefotaxime, cefoperazone, piperacillin, and aminoglycosides against gram-negative bacilli. Antimicrob Agents Chemother (1980) 2.23
Kinetics of the synergism of penicillin-streptomycin and penicillin-kanamycin for enterococci and its relationship to L-phase variants. J Lab Clin Med (1966) 2.14
Piperacillin therapy for serious bacterial infections. Am J Med (1980) 2.14
Endocarditis due to Micrococci and Staphylococcus epidermidis. Arch Intern Med (1973) 2.12
Report of the Institute of Medicine Committee on the Efficacy and Safety of Halcion. Arch Gen Psychiatry (1999) 2.03
Drugs as etiologic factors in the Stevens-Johnson syndrome. Am J Med (1968) 1.98
Three new long-acting converting-enzyme inhibitors: relationship between plasma converting-enzyme activity and response to angiotensin I. Clin Pharmacol Ther (1981) 1.88
Antimicrobial synergism in the therapy of gram-negative rod bacteremia. Chemotherapy (1978) 1.88
Comparative efficacy and toxicity of amikacin/carbenicillin versus gentamicin/carbenicillin in leukopenic patients: a randomized prospective trail. Am J Med (1977) 1.86
Plasma protein binding of tricyclic anti-depressants in man. Biochem Pharmacol (1969) 1.86
Combined use of gentamicin and carbenicillin. Ann Intern Med (1971) 1.81
Commentary: therapeutics and government: 1776 and 1976. Clin Pharmacol Ther (1976) 1.74
Improved acetylating radioenzymatic assay of amikacin, tobramycin, and sisomicin in serum. Antimicrob Agents Chemother (1975) 1.63
Simultaneous antibiotic levels in "breakthrough" gram-negative rod bacteremia. Am J Med (1976) 1.62
Pharmacokinetics of methotrexate. Clin Pharmacol Ther (1973) 1.55
The acylampicillins: mezlocillin, piperacillin, and azlocillin. Rev Infect Dis (1984) 1.48
Gentamicin: toxicity in perspective. Postgrad Med J (1974) 1.41
Pyelonephritis. XII. Comparison of penicillin, ampicillin, and streptomycin in enterococcal infection in rats. J Infect Dis (1971) 1.39
The effect of spironolactone on antipyrine metabolism in man. Pharmacology (1973) 1.31
Activity of three aminoglycosides and two penicillins against four species of gram-negative bacilli. Antimicrob Agents Chemother (1975) 1.30
Computer-controlled infusion of intravenous dexmedetomidine hydrochloride in adult human volunteers. Anesthesiology (1993) 1.30
Correlation of the plasma elimination of antipyrine and the appearance of 4-hydroxy antipyrine in the urine of man. Biochem Pharmacol (1974) 1.28
Absorption of orally given digoxin preparations. JAMA (1972) 1.27
Melphalan in multiple myeloma. Blood (1967) 1.25
Ototoxicity of amikacin. Antimicrob Agents Chemother (1976) 1.25
The effects of urine pH and plasma protein binding on the renal clearance of disopyramide. Clin Pharmacokinet (1977) 1.25
Effect of route of administration and effusions on methotrexate pharmacokinetics. Cancer Res (1974) 1.22
Infectious osteitis pubis. Urology (1978) 1.22
Nafenopin-induced hepatic microbody (peroxisome) proliferation and catalase synthesis in rats and mice. Absence of sex difference in response. J Cell Biol (1974) 1.21
The frequency of long-term remission in patients with acute myelogenous leukaemia treated with conventional maintenance chemotherapy: a study of 760 patients with a minimal follow-up time of 6 years. Br J Haematol (1989) 1.21
Fungal infection in acute leukemia. Cancer (1972) 1.17
Phenytoin: pharmacokinetics and bioavailability. Clin Pharmacol Ther (1976) 1.14
Di-(2-ethylhexyl)phthalate: an industrial plasticizer induces hypolipidemia and enhances hepatic catalase and carnitine acetyltransferase activities in rat and mice. Life Sci (1976) 1.14
Intracerebral involvement in Hodgkin's disease: a report of 6 cases and review of the literature. Cancer (1979) 1.14
Long-term effects of clofibrate (Atromid-S) on serum lipids in man. Circulation (1969) 1.11
The accumulation and metabolism of dopamine by the human platelet. Clin Pharmacol Ther (1971) 1.09
Mitogenic and carcinogenic effects of a hypolipidemic peroxisome proliferator, [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14, 643), in rat and mouse liver. Cancer Res (1979) 1.09
Theophylline bioavailability following chronic dosing of an elixir and two solid dosage forms. J Pharm Sci (1978) 1.09
The human platelet as a pharmacologic model for the adrenergic neuron. The uptake and release of norepinephrine. Clin Pharmacol Ther (1969) 1.08
125I-Radioimmunoassay of amikacin and comparison with a microbioassay. J Antibiot (Tokyo) (1976) 1.08
Drugs and drug metabolites as environmental contaminants: chlorophenoxyisobutyrate and salicyclic acid in sewage water effluent. Life Sci (1977) 1.07
Coccidioidal meningitis. An analysis of thirty-one cases and review of the literature. Medicine (Baltimore) (1981) 1.07
Relationships among timolol doses, plasma concentrations and beta-adrenoceptor blocking activity. Br J Clin Pharmacol (1982) 1.06
Clinical complications of corticosteroid therapy. A selected review. Med Clin North Am (1973) 1.06
Clinical importance of myeloid antigen expression in adult acute lymphoblastic leukemia. N Engl J Med (1987) 1.06
Blood level determinations of antimicrobial drugs. Some clinical considerations. Med Clin North Am (1978) 1.05
Metabolic responses to acute and chronic L-dopa administration in patients with parkinsonism. N Engl J Med (1972) 1.04
Association of certain Ia allotypes with the occurrence of chronic lymphocytic leukemia. Recognition by a monoclonal anti-Ia reagent of a susceptibility determinant not in the DR series. J Exp Med (1982) 1.03
Reflections on the clinical pharmacology of gentamicin. Acta Pathol Microbiol Scand B Microbiol Immunol (1973) 1.03
Effect of in vivo elevation of free fatty acids on protein binding of drugs. Pharmacology (1974) 1.02
Thrombotic thrombocytopenic purpura: a ten-year experience. Blood (1980) 1.02
The UCLA interdepartmental conference. Opportunistic pulmonary infections. Ann Intern Med (1966) 1.02
Observations on cell lines derived from a patient with Hodgkin's disease. Cancer Res (1978) 1.01
Tumors in male rats fed ethyl chlorophenoxyisobutyrate, a hypolipidemic drug. Cancer Res (1979) 1.00
The alteration of plasma proteins in uremia as reflected in their ability to bind digitoxin and diphenylhydantoin. Pharmacology (1972) 1.00
High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. J Exp Med (1987) 1.00
Correlation between plasma diphenhydramine level and sedative and antihistamine effects. Clin Pharmacol Ther (1978) 0.99
Clinical pharmacokinetics of methotrexate. Clin Pharmacokinet (1978) 0.99
Necrotizing pneumonitis and empyema due to microaerophilic streptococci. N Engl J Med (1965) 0.97
Vincristine-induced bladder atony. Cancer (1971) 0.97
Prescription writing by generic name and drug cost. J Chronic Dis (1967) 0.96
The influence of debrisoquin on the accumulation and metabolism of biogenic amines by the human platelet, in vivo and in vitro. Clin Pharmacol Ther (1969) 0.96
Hepatic effects of some [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio] acetic acid (WY-14,643) analogs in the mouse. Arch Int Pharmacodyn Ther (1977) 0.95
Drug interactions with warfarin. Arch Intern Med (1968) 0.95
Vincristine, prednisone and L-asparaginase in the induction of remission in children with acute lymphoblastic leukemia following relapse. Cancer (1978) 0.95
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats. Eur J Pharmacol (1970) 0.95
Piperacillin plus amikacin therapy v carbenicillin plus amikacin therapy in febrile, granulocytopenic patients. Arch Intern Med (1982) 0.95
Effect of portacaval shunt on the disposition of drugs with and without first-pass effect. J Pharmacol Exp Ther (1975) 0.94
The natural penicillins. Med Clin North Am (1970) 0.93
Drug interactions. Pharmacol Physicians (1970) 0.93
Microbodies in experimentally altered cells. VI. Thyroxine displacement from plasma proteins and clofibrate effect. Arch Int Pharmacodyn Ther (1969) 0.93
Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine in humans. Cancer Res (1974) 0.92
Drug protein binding and the nephrotic syndrome. Clin Pharmacokinet (1976) 0.92
125I radioimmunoassay of netilmicin. Antimicrob Agents Chemother (1977) 0.92
Pharmacokinetics of drugs in patients with the nephrotic syndrome. J Clin Invest (1975) 0.92
Splenectomy, steroids, and dextran 70 in thrombotic thrombocytopenic purpura. JAMA (1974) 0.92
Comparative in vitro susceptibility of yeasts to amphotericin B and three methyl ester derivatives. Antimicrob Agents Chemother (1981) 0.91
Combination chemotherapy and radiotherapy for acute lymphocytic leukemia in adults: results of CALGB protocol 7113. Leuk Res (1979) 0.91
Treatment of acute myeloid leukemia cells in vitro with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed. J Clin Invest (1987) 0.91
Efficacy of daunorubicin in the therapy of adult acute lymphocytic leukemia: a prospective randomized trial by cancer and leukemia group B. Blood (1984) 0.91
Association of monocytic leukemia in patients with extreme leukocytosis. Am J Med (1980) 0.90
Tartrate-resistant acid phosphatase staining of monocytes in Gaucher disease. Am J Hematol (1985) 0.89
Myeloma proteins, Bence Jones proteins and normal immunoglobulins in multiple myeloma. Blood (1967) 0.89
A new approach to the use of histamine skin tests in the study of antihistamine drugs. Clin Pharmacol Ther (1969) 0.89
Pseudomonas maltophilia exoenzyme activity as correlate in pathogenesis of ecthyma gangrenosum. J Clin Microbiol (1986) 0.88
The effect of butoxamine on catecholamine-induced metabolic changes in humans. Clin Pharmacol Ther (1966) 0.87
Overview: the role of angiotensin-converting enzyme inhibitors in cardiovascular therapy. Fed Proc (1984) 0.87
Induction of salicyluric acid formation in rheumatoid arthritis patients treated with salicylates. Clin Pharmacokinet (1983) 0.87
Synergy between high-dose cytarabine and asparaginase in the treatment of adults with refractory and relapsed acute myelogenous leukemia--a Cancer and Leukemia Group B Study. J Clin Oncol (1988) 0.87
Effectiveness of antibiotics against the bacterial and "protoplast" phases of pyelonephritis. Antimicrob Agents Chemother (Bethesda) (1965) 0.87