Microcystins (cyanobacterial toxins) in drinking water enhance the growth of aberrant crypt foci in the mouse colon.

PubWeight™: 0.97‹?› | Rank: Top 15%

🔗 View Article (PMID 11036504)

Published in J Toxicol Environ Health A on October 13, 2000

Authors

A R Humpage1, S J Hardy, E J Moore, S M Froscio, I R Falconer

Author Affiliations

1: Department of Clinical and Experimental Pharmacology, University of Adelaide, Australia.

Articles citing this

Molecular mechanisms of microcystin toxicity in animal cells. Int J Mol Sci (2010) 1.30

Comparative cellular toxicity of hydrophilic and hydrophobic microcystins on Caco-2 cells. Toxins (Basel) (2012) 0.99

Monitoring changing toxigenicity of a cyanobacterial bloom by molecular methods. Appl Environ Microbiol (2002) 0.98

Cyanobacterial cyclopeptides as lead compounds to novel targeted cancer drugs. Mar Drugs (2010) 0.96

Health risk assessment for cyanobacterial toxins in seafood. Int J Environ Res Public Health (2012) 0.91

Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer. J Cancer Res Clin Oncol (2012) 0.89

Effect of microcystin-LR on protein phosphatase 2A and its function in human amniotic epithelial cells. J Zhejiang Univ Sci B (2011) 0.77

Dynamics of protein phosphatase gene expression in Corbicula fluminea exposed to microcystin-LR and to toxic Microcystis aeruginosa cells. Int J Mol Sci (2011) 0.77

Genotoxicity of microcystin-LR in in vitro and in vivo experimental models. Biomed Res Int (2014) 0.76

Variable Cyanobacterial Toxin and Metabolite  Profiles across Six Eutrophic Lakes of Differing  Physiochemical Characteristics. Toxins (Basel) (2017) 0.75

Brewers' Rice: A By-Product from Rice Processing Provides Natural Hepatorenal Protection in Azoxymethane-Induced Oxidative Stress in Rats. Oxid Med Cell Longev (2015) 0.75

Isolation and structure determination of a proteasome inhibitory metabolite from a culture of Scytonema hofmanni. J Microbiol Biotechnol (2008) 0.75

Microcystins contamination of surface water supply sources in Zaria-Nigeria. Environ Monit Assess (2015) 0.75

Articles by these authors

(truncated to the top 100)

The ribosomal proteins of Escherichia coli. I. Purification of the 30S ribosomal proteins. Biochemistry (1969) 7.47

Correlation of competence for export with lack of tertiary structure of the mature species: a study in vivo of maltose-binding protein in E. coli. Cell (1986) 5.09

Synthesis of exported proteins by membrane-bound polysomes from Escherichia coli. Eur J Biochem (1977) 3.74

Precursors of three exported proteins in Escherichia coli. Proc Natl Acad Sci U S A (1978) 2.91

Synthesis of a precursor to the B subunit of heat-labile enterotoxin in Escherichia coli. J Bacteriol (1981) 2.84

Energy is required for maturation of exported proteins in Escherichia coli. Eur J Biochem (1981) 2.70

Export of protein in bacteria. Microbiol Rev (1984) 2.35

The ribosomal proteins of Escherichia coli. II. Chemical and physical characterization of the 30S ribosomal proteins. Biochemistry (1969) 2.26

Effect of Escherichia coli on fluid transport across canine small bowel. Mechanism and time-course with enterotoxin and whole bacterial cells. J Clin Invest (1973) 2.25

Unity in function in the absence of consensus in sequence: role of leader peptides in export. Science (1989) 2.12

Mechanism of toxin secretion by Vibrio cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins of Escherichia coli. Proc Natl Acad Sci U S A (1984) 2.10

The stoichiometry of the ribosomal proteins of Escherichia coli. Mol Gen Genet (1975) 2.06

Export of protein: a biochemical view. Annu Rev Microbiol (1987) 2.02

No specific recognition of leader peptide by SecB, a chaperone involved in protein export. Science (1990) 1.75

Cellular location of heat-labile enterotoxin in Escherichia coli. J Bacteriol (1984) 1.71

The ribosomal protein L8 is a complex L7/L12 and L10. FEBS Lett (1976) 1.68

Physical and functional heterogeneity of E. coli ribosomes. Cold Spring Harb Symp Quant Biol (1969) 1.67

Preoperative and postoperative topical tretinoin on high-tension excisional wounds and full-thickness skin grafts in a porcine model: A pilot study. Dermatol Surg (1999) 1.42

High selectivity with low specificity: how SecB has solved the paradox of chaperone binding. Trends Biochem Sci (1995) 1.41

Health risks caused by freshwater cyanobacteria in recreational waters. J Toxicol Environ Health B Crit Rev (2000) 1.39

Review by a local medical research ethics committee of the conduct of approved research projects, by examination of patients' case notes, consent forms, and research records and by interview. BMJ (1997) 1.37

Severe hepatotoxicity caused by the tropical cyanobacterium (blue-green alga) Cylindrospermopsis raciborskii (Woloszynska) Seenaya and Subba Raju isolated from a domestic water supply reservoir. Appl Environ Microbiol (1985) 1.36

Evidence of liver damage by toxin from a bloom of the blue-green alga, Microcystis aeruginosa. Med J Aust (1983) 1.35

School screening for scoliosis. Lancet (1981) 1.30

Isolation and toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon (1997) 1.29

Novel intermediates in the synthesis of maltose-binding protein in Escherichia coli. Eur J Biochem (1980) 1.28

Effects of intraductal administration of prolactin, actinomycin D and cycloheximide on lipoprotein lipase activity in the mammary glands of pseudopregnant rabbits. Biochim Biophys Acta (1970) 1.20

Effects of intraductal prolactin on some aspects of the ultrastructure and biochemistry of mammary tissue in the pseudopregnant rabbit. J Endocrinol (1971) 1.20

Toxicity of the cyanobacterium Nodularia spumigena Mertens. Toxicon (1988) 1.20

Prospective analysis of the efficacy of continuous intraoperative nerve monitoring during thyroidectomy, parathyroidectomy, and parotidectomy. Otolaryngol Head Neck Surg (2001) 1.19

Clinical and pathological changes in sheep experimentally poisoned by the blue-green alga Microcystis aeruginosa. Vet Pathol (1984) 1.17

Assembly in vivo of enterotoxin from Escherichia coli: formation of the B subunit oligomer. J Bacteriol (1983) 1.16

Tumour promotion by Microcystis sp., a blue-green alga occurring in water supplies. Med J Aust (1989) 1.15

Complexes between protein export chaperone SecB and SecA. Evidence for separate sites on SecA providing binding energy and regulatory interactions. J Biol Chem (2000) 1.13

Isolation, characterization and pathology of the toxin from a Microcystis aeruginosa (= Anacystis cyanea) bloom. Aust J Biol Sci (1978) 1.12

The effect of actinomycin D and cycloheximide on the activition by prolactin of lipoprotein lipase in the mammary gland. Biochem J (1968) 1.09

Processing in vitro of precursor periplasmic proteins from Escherichia coli. Eur J Biochem (1978) 1.08

Micronucleus induction and chromosome loss in transformed human white cells indicate clastogenic and aneugenic action of the cyanobacterial toxin, cylindrospermopsin. Mutat Res (2000) 1.07

Improved long term survival after intracavitary interleukin-2 and lymphokine-activated killer cells for adults with recurrent malignant glioma. Cancer (1995) 1.06

Hearing aid orientation in a state school for the mentally retarded. J Speech Hear Disord (1969) 1.02

Studies of the congenitally goitrous sheep. The iodinated compounds of serum, and circulating thyroid-stimulating hormone. Biochem J (1966) 1.01

Binding of SecB to ribosome-bound polypeptides has the same characteristics as binding to full-length, denatured proteins. Proc Natl Acad Sci U S A (1997) 1.01

The relationship between poly A polymerase and the ribosomes. Biochemistry (1966) 0.99

Neutrophil migration inhibitory properties of polyunsaturated fatty acids. The role of fatty acid structure, metabolism, and possible second messenger systems. J Clin Invest (1994) 0.99

Calorimetric analyses of the interaction between SecB and its ligands. Protein Sci (1998) 0.98

Autoantibodies against mouse bromelain-modified RBC are specifically inhibited by a common membrane phospholipid, phosphatidylcholine. Immunology (1985) 0.97

Oral toxicity of the cyanobacterial toxin cylindrospermopsin in male Swiss albino mice: determination of no observed adverse effect level for deriving a drinking water guideline value. Environ Toxicol (2003) 0.97

Determination of the binding frame of the chaperone SecB within the physiological ligand oligopeptide-binding protein. Protein Sci (1997) 0.96

Preliminary evidence of toxicity associated with the benthic cyanobacterium Phormidium in South Australia. Environ Toxicol (2001) 0.95

SecB: a chaperone from Escherichia coli. Methods Enzymol (1998) 0.94

Effect of 22-32 carbon n-3 polyunsaturated fatty acids on superoxide production in human neutrophils: synergism of docosahexaenoic acid with f-met-leu-phe and phorbol ester. Immunology (1991) 0.93

Effect of toxin from the cyanobacterium Microcystis aeruginosa on ultrastructural morphology and actin polymerization in isolated hepatocytes. Toxicon (1986) 0.92

Withdrawal of funds for animal experiments at the University of Pennsylvania. Br Med J (Clin Res Ed) (1985) 0.92

Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitus. Diabet Med (2003) 0.91

Exchange of ribosomal proteins among the ribosomes of Escherichia coli. Mol Gen Genet (1977) 0.90

The localization of prolactin labelled with radioactive iodine in rabbit mammary tissue. J Endocrinol (1972) 0.89

Injury to hepatocytes induced by a peptide toxin from the cyanobacterium Microcystis aeruginosa. Toxicon (1987) 0.89

The effect of adrenaline and noradrenaline on hormone secretion and blood flow from the thyroid vein in sheep with exteriorized thyroids. J Physiol (1967) 0.89

The polynucleotide product of poly A polymerase from Escherichia coli. Biochemistry (1966) 0.88

The effect of vasopressin on hormone secretion and blood flow from the thyroid vein in sheep with exteriorized thyroids. J Physiol (1968) 0.88

Stabilization of 70S ribosomes by spermidine. Nat New Biol (1971) 0.88

Mercury (Hg2+) suppression of potassium currents of outer hair cells. Neurotoxicol Teratol (2003) 0.87

Preparation of free and membrane-bound polysomes from Escherichia coli. Methods Enzymol (1983) 0.86

Kinetic and thermodynamic acidity of hydrido transition-metal complexes. 3. Thermodynamic acidity of common mononuclear carbonyl hydrides. J Am Chem Soc (1986) 0.86

Comparison of analytical tools and biological assays for detection of paralytic shellfish poisoning toxins. Anal Bioanal Chem (2010) 0.85

Interaction of the cyanobacterial toxin cylindrospermopsin with the eukaryotic protein synthesis system. Toxicon (2007) 0.85

Effect of prolactin on sodium and potassium concentrations in mammary alveolar tissue. Endocrinology (1977) 0.84

Inhibition by low concentrations of ouabain of prolactin-induced lactogenesis in rabbit mammary-gland explants. Biochem J (1978) 0.83

Possible mechanism for action of prolactin on mammary cell sodium transport. Nature (1975) 0.82

Silver plated ribosomes. Nat New Biol (1971) 0.82

The cyanobacterial toxin, cylindrospermopsin, induces fetal toxicity in the mouse after exposure late in gestation. Toxicon (2007) 0.82

Position of the extra amino acid sequence in the precursor arabinose-binding protein of Escherichia coli. J Bacteriol (1978) 0.81

Deformation of isolated rat hepatocytes by a peptide hepatotoxin from the blue-green alga microcystis aeruginosa. Naunyn Schmiedebergs Arch Pharmacol (1981) 0.81

The I' potential of the human auditory brainstem response to paired click stimuli. Scand Audiol (2001) 0.81

Cell-free protein synthesis inhibition assay for the cyanobacterial toxin cylindrospermopsin. Environ Toxicol (2001) 0.81

Aspects of the biochemistry, physiology and endocrinology of lactation. Aust J Biol Sci (1980) 0.81

The interaction between the chaperone SecB and its ligands: evidence for multiple subsites for binding. Protein Sci (1998) 0.81

Short-circuit current across isolated rabbit ileum, jejunum and duodenum. Proc Soc Exp Biol Med (1973) 0.81

The uptake of the cyanobacterial hepatotoxin microcystin by isolated rat hepatocytes. Toxicon (1991) 0.81

Heat-labile enterotoxin can be released from Escherichia coli cells by host intestinal factors. Infect Immun (1991) 0.80

British criteria for brain death: views of career grade doctors in Scotland. Br Med J (Clin Res Ed) (1984) 0.80

Effect of nigericin and varying potassium concentrations on the prolactin-stimulated synthesis of milk fat in explants of mammary alveolar tissue from rabbits. J Endocrinol (1983) 0.80

Phorbol ester induces differential membrane-association of protein kinase C subspecies in human platelets. Biochem Biophys Res Commun (1989) 0.80

Direct demonstration that homotetrameric chaperone SecB undergoes a dynamic dimer-tetramer equilibrium. J Biol Chem (2000) 0.80

Evaluation of the Abraxis Strip Test for Microcystins™ for use with wastewater effluent and reservoir water. Water Res (2011) 0.80

Studies on the congenitally goitrous sheep. Iodoproteins of the goitre. Biochem J (1970) 0.80

The promiscuous and specific sides of SecB. Nat Struct Biol (2000) 0.79

Enzymic assay of adenosine 3',5'-monophosphate. Anal Biochem (1965) 0.79

Biological half-life, organ distribution and excretion of 125-I-labelled toxic peptide from the blue-green alga Microcystis aeruginosa. Aust J Biol Sci (1986) 0.79

Lead (Pb2+) modulation of potassium currents of guinea pig outer hair cells. Neurotoxicol Teratol (2004) 0.78

Lethal potency and tissue distribution of 125I-labelled toxic peptides from the blue-green alga Microcystis aeruginosa. Toxicon (1986) 0.78

Studies of the congenitally goitrous sheep. Composition and metabolism of goitrous thyroid tissue. Biochem J (1966) 0.78

Effect of progesterone alone and in combination with either corticosterone, 17 beta-estradiol or insulin on prolactin-stimulated fatty acid synthesis in mammary explants from pseudopregnant rabbits. Aust J Biol Sci (1984) 0.77

Thyroxine utilization in lambs in natural and controlled environments. J Endocrinol (1970) 0.77

Structural determinant of a ribosomal protein: K locus. Science (1969) 0.77

Effective hand hygiene education with the use of flipcharts in a hospital in El Salvador. J Hosp Infect (2006) 0.77

Stimulation of DNA synthesis by prolactin in rabbit mammary tissue. J Cell Sci (1974) 0.77

Processing of exported proteins in Escherichia coli. Biochem Soc Trans (1980) 0.77

Effect of prolactin on 86Rb+ uptake, potassium content and [G-3H]ouabain binding of lactating rabbit mammary tissue. J Physiol (1983) 0.76

Flow-cytometric analysis of in vitro micronucleus formation: comparative studies with WIL2-NS human lymphoblastoid and L5178Y mouse lymphoma cell lines. Mutat Res (2008) 0.76