Published in Trends Biochem Sci on October 01, 2000
Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3. EMBO J (2004) 3.51
The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci (2008) 3.04
Requirement for Arf6 in breast cancer invasive activities. Proc Natl Acad Sci U S A (2004) 2.37
Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway. Mol Biol Cell (2002) 1.72
GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid. Biochemistry (2004) 1.48
Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction. Biophys J (2009) 1.44
GTP/GDP exchange by Sec12p enables COPII vesicle bud formation on synthetic liposomes. EMBO J (2004) 1.43
ARF-GEP(100), a guanine nucleotide-exchange protein for ADP-ribosylation factor 6. Proc Natl Acad Sci U S A (2001) 1.41
Single molecule diffusion of membrane-bound proteins: window into lipid contacts and bilayer dynamics. Biophys J (2010) 1.35
Distinguishing modes of eukaryotic gradient sensing. Biophys J (2005) 1.22
GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins. Mol Cell Biol (2003) 1.18
ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling. Mol Biol Cell (2007) 1.16
Arf6 plays an early role in platelet activation by collagen and convulxin. Blood (2005) 1.12
Divergent roles of c-Src in controlling platelet-derived growth factor-dependent signaling in fibroblasts. Mol Biol Cell (2005) 1.00
Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. J Biol Chem (2008) 0.97
The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry (2011) 0.93
Gamma-aminobutyric acid type B (GABA(B)) receptor internalization is regulated by the R2 subunit. J Biol Chem (2011) 0.87
Remobilization of Tol2 transposons in Xenopus tropicalis. BMC Dev Biol (2010) 0.87
The neuronal Arf GAP centaurin alpha1 modulates dendritic differentiation. J Cell Sci (2007) 0.87
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice. Proc Natl Acad Sci U S A (2007) 0.85
Cytohesin binder and regulator (cybr) is not essential for T- and dendritic-cell activation and differentiation. Mol Cell Biol (2006) 0.85
Identification of a guanine nucleotide exchange factor for Arf3, the yeast orthologue of mammalian Arf6. PLoS One (2007) 0.85
Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One (2012) 0.84
GxcDD, a putative RacGEF, is involved in Dictyostelium development. BMC Cell Biol (2007) 0.82
Bias in the gradient-sensing response of chemotactic cells. J Theor Biol (2007) 0.81
Specificity and membrane partitioning of Grsp1 signaling complexes with Grp1 family Arf exchange factors. Biochemistry (2010) 0.81
Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton. J Biol Chem (2011) 0.80
The roles of PIKE in tumorigenesis. Acta Pharmacol Sin (2013) 0.80
Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans. Genetics (2014) 0.80
Phosphoinositide 3-kinase enhancer (PIKE) in the brain: is it simply a phosphoinositide 3-kinase/Akt enhancer? Rev Neurosci (2012) 0.78
Cytohesins and centaurins: mediators of PI 3-kinase regulated Arf signaling. Trends Biochem Sci (2001) 0.77
Novel candidate key drivers in the integrative network of genes, microRNAs, methylations, and copy number variations in squamous cell lung carcinoma. Biomed Res Int (2015) 0.76
The PIKE homolog Centaurin gamma regulates developmental timing in Drosophila. PLoS One (2014) 0.76
Role of Host Type IA Phosphoinositide 3-Kinase Pathway Components in Invasin-Mediated Internalization of Yersinia enterocolitica. Infect Immun (2016) 0.76
Grp1-associated scaffold protein (GRASP) is a regulator of the ADP ribosylation factor 6 (Arf6)-dependent membrane trafficking pathway. Cell Biol Int (2012) 0.76
What we have learnt about PIKE from the knockout mice. Int J Biochem Mol Biol (2011) 0.75
Localization of EFA6A, a guanine nucleotide exchange factor for ARF6, in spermatogenic cells of testes of adult mice. J Mol Histol (2008) 0.75
Tumor Necrosis Factor a Promotes Phosphoinositide 3-Kinase Enhancer A and Amp-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle. Diabetes (2017) 0.75
Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J (1996) 1.89
Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. Mol Biol Cell (1999) 1.55
Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. J Cell Biol (2000) 1.33
Identification and cloning of centaurin-alpha. A novel phosphatidylinositol 3,4,5-trisphosphate-binding protein from rat brain. J Biol Chem (1996) 1.28
Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity. J Biol Chem (2000) 1.22
Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2. Biochem Biophys Res Commun (1992) 1.22
Sac1p plays a crucial role in microsomal ATP transport, which is distinct from its function in Golgi phospholipid metabolism. EMBO J (1999) 1.19
Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase. J Cell Sci (1996) 1.18
GCS1, an Arf guanosine triphosphatase-activating protein in Saccharomyces cerevisiae, is required for normal actin cytoskeletal organization in vivo and stimulates actin polymerization in vitro. Mol Biol Cell (1999) 1.05
Thrombospondin signaling of focal adhesion disassembly requires activation of phosphoinositide 3-kinase. J Biol Chem (1998) 0.96
Monitoring Chinese hamster ovary cell culture by the analysis of glucose and lactate metabolism. J Biotechnol (2005) 0.95
The yeast BSD2-1 mutation influences both the requirement for phosphatidylinositol transfer protein function and derepression of phospholipid biosynthetic gene expression in yeast. Genetics (1996) 0.93
Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins. J Biol Chem (2001) 0.85
Elevated adenosine monophosphate deaminase activity in Alzheimer's disease brain. Neurobiol Aging (1999) 0.83
Regulation of AMP deaminase by phosphoinositides. J Biol Chem (1999) 0.83
Cytohesins and centaurins: mediators of PI 3-kinase regulated Arf signaling. Trends Biochem Sci (2001) 0.77
Cocaine-inhibited neuronal differentiation in NGF-induced PC12 cells and altered c-fos expression are reversed by C-fos antisense oligonucleotide. Ann N Y Acad Sci (1998) 0.75
Cocaine inhibition of neuronal differentiation in NGF-induced PC12 cells is independent of ras signaling. Int J Dev Neurosci (2000) 0.75
C-fos mediates cocaine inhibition of NGF-induced PC12 cell differentiation. Mol Genet Metab (1998) 0.75