Chromosomal instability induced by heavy ion irradiation.

A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. Cancer Res (2006) 1.34

Heavy ions, radioprotectors and genomic instability: implications for human space exploration. Radiat Environ Biophys (2009) 0.91

Germ cell mutagenesis in medaka fish after exposures to high-energy cosmic ray nuclei: A human model. Proc Natl Acad Sci U S A (2005) 0.86

Genetic and epigenetic changes in chromosomally stable and unstable progeny of irradiated cells. PLoS One (2014) 0.81

Detection of chromosomal instability in bystander cells after Si490-ion irradiation. Radiat Res (2011) 0.81

Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability. Free Radic Biol Med (2012) 0.77

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell (1998) 6.58

Telomere dynamics in an immortal human cell line. EMBO J (1994) 3.22

Genomic instability in Gadd45a-deficient mice. Nat Genet (1999) 3.01

Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome. Mol Cell Biol (1994) 1.96

Cell electroporation is a highly efficient method for introducing restriction endonucleases into cells. Mutat Res (1989) 1.50

Delayed chromosomal instability induced by DNA damage. Mol Cell Biol (1993) 1.46

Chlorpyrifos oxon binds directly to muscarinic receptors and inhibits cAMP accumulation in rat striatum. J Pharmacol Exp Ther (1994) 1.25

A proposed system for scoring structural aberrations detected by chromosome painting. Cytogenet Cell Genet (1995) 1.22

Spectrum of mutations produced by specific types of restriction enzyme-induced double-strand breaks. Mutagenesis (1992) 1.22

Calcium uptake and catecholamine secretion by cultured bovine adrenal medulla cells. J Neurochem (1982) 1.21

Noncomplementary DNA double-strand-break rejoining in bacterial and human cells. Nucleic Acids Res (1993) 1.16

Unique DNA repair properties of a xeroderma pigmentosum revertant. Mol Cell Biol (1987) 1.14

Redox changes induced in hippocampal precursor cells by heavy ion irradiation. Radiat Environ Biophys (2006) 1.11

Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair. Proc Natl Acad Sci U S A (2000) 1.11

Chromosomal instability and its relationship to other end points of genomic instability. Cancer Res (1997) 1.09

Pol eta is required for DNA replication during nucleotide deprivation by hydroxyurea. Oncogene (2007) 1.06

DNA double-strand breaks, chromosomal rearrangements, and genomic instability. Mutat Res (1998) 1.05

Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity. Cancer Res (1998) 1.03

Differences in the regulation by poly(ADP-ribose) of repair of DNA damage from alkylating agents and ultraviolet light according to cell type. J Biol Chem (1983) 1.00

Differential induction of chromosomal instability by DNA strand-breaking agents. Cancer Res (1997) 0.96

Attenuation of radiation-induced genomic instability by free radical scavengers and cellular proliferation. Free Radic Biol Med (2001) 0.96

Genomic instability induced by high and low LET ionizing radiation. Adv Space Res (2000) 0.95

Critical target and dose and dose-rate responses for the induction of chromosomal instability by ionizing radiation. Radiat Res (1999) 0.94

Chromosomal changes without DNA overproduction in hydroxyurea-treated mammalian cells: implications for gene amplification. Cancer Res (1986) 0.94

X-ray induction of methotrexate resistance due to dhfr gene amplification. Somat Cell Mol Genet (1990) 0.94

Inhibition of malignant transformation in vitro by inhibitors of poly(ADP-ribose) synthesis. Proc Natl Acad Sci U S A (1984) 0.94

Evidence for secretory granule membrane recycling in cultured adrenal chromaffin cells. Cell Biol Int Rep (1981) 0.93

DNA end joining by the Klenow fragment of DNA polymerase I. J Biol Chem (1996) 0.93

3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light. Mutat Res (1982) 0.92

Low doses of very low-dose-rate low-LET radiation suppress radiation-induced neoplastic transformation in vitro and induce an adaptive response. Radiat Res (2008) 0.92

Recombination involving interstitial telomere repeat-like sequences promotes chromosomal instability in Chinese hamster cells. Carcinogenesis (1998) 0.91

Radiation-induced instability and its relation to radiation carcinogenesis. Int J Radiat Biol (1998) 0.91

Poly(ADP-ribose)polymerase: a perplexing participant in cellular responses to DNA breakage. Mutat Res (1991) 0.90

Bridging the gap. Joining of nonhomologous ends by DNA polymerases. J Biol Chem (1994) 0.90

Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance. Biochim Biophys Acta (1996) 0.89

Analysis of human lymphocyte cell cycle time in culture measured by sister chromatid differential staining. Exp Cell Res (1977) 0.89

Tubulin as a major cell surface protein in human lymphoid cells of leukemic origin. Cancer Res (1982) 0.88

Effect of 3-aminobenzamide on the rate of ligation during repair of alkylated DNA in human fibroblasts. Cancer Res (1983) 0.88

Novel approaches with track segment alpha particles and cell co-cultures in studies of bystander effects. Radiat Prot Dosimetry (2002) 0.87

Alternative recombination pathways in UV-irradiated XP variant cells. Oncogene (2005) 0.87

Analysis of restriction enzyme-induced DNA double-strand breaks in Chinese hamster ovary cells by pulsed-field gel electrophoresis: implications for chromosome damage. Radiat Res (1991) 0.87

Profiling mitochondrial proteins in radiation-induced genome-unstable cell lines with persistent oxidative stress by mass spectrometry. Radiat Res (2008) 0.86

The relative biological importance of cyclobutane and (6-4) pyrimidine-pyrimidone dimer photoproducts in human cells: evidence from a xeroderma pigmentosum revertant. Photochem Photobiol (1988) 0.86

Compliance of Victorian dairy farmers with current calf rearing recommendations for control of Johne's disease. Vet Microbiol (2000) 0.86

Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymes. Mutat Res (1993) 0.85

The frequency and distribution of sister chromatid exchanges in human chromosomes. Hum Genet (1977) 0.85

Lymphocyte proliferation in Down's syndrome measured by sister chromatid differential staining. Hum Genet (1980) 0.85

The role of acentric chromosome fragments in gene amplification. Somat Cell Mol Genet (1987) 0.85

Subcellular fractions of the adrenal medulla. Comparison by two-dimensional polyacrylamide gel electrophoresis. Biochim Biophys Acta (1982) 0.84

Nuclear fragmentation and premature chromosome condensation induced by heat shock in S-phase Chinese hamster ovary cells. Cancer Res (1988) 0.83

Morphological transformation of 10T1/2 mouse embryo cells can be initiated by DNA double-strand breaks alone. Mol Carcinog (1991) 0.83

The Impact of Biology on Risk Assessment--workshop of the National Research Council's Board on Radiation Effects Research. July 21-22, 1997, National Academy of Sciences, Washington, DC. Radiat Res (1998) 0.82

Cytogenetic damage and the radiation-induced G1-phase checkpoint. Radiat Res (1996) 0.82

A role for chromosomal instability in the development of and selection for radioresistant cell variants. Br J Cancer (2001) 0.82

Shared oxidative pathways in response to gravity-dependent loading and gamma-irradiation of bone marrow-derived skeletal cell progenitors. Radiats Biol Radioecol (2007) 0.82

Telomeres and their possible role in chromosome stabilization. Environ Mol Mutagen (1993) 0.82

Flux of catecholamines through chromaffin vesicles in cultured bovine adrenal medullary cells. J Biol Chem (1984) 0.82

PAINT: a proposed nomenclature for structural aberrations detected by whole chromosome painting. Mutat Res (1995) 0.81

Proliferation of PHA-stimulated lymphocytes measured by combined autoradiography sister chromatid differential staining. Exp Cell Res (1979) 0.81

Metabolic pools of ATP in cultured bovine adrenal medullary chromaffin cells. J Neurochem (1986) 0.81

The incidence of sister chromatid exchanges in cultured human lymphocytes. Mutat Res (1977) 0.81

Modulation of restriction enzyme-induced damage by chemicals that interfere with cellular responses to DNA damage: a cytogenetic and pulsed-field gel analysis. Radiat Res (1991) 0.81

A cytogenetic investigation of DNA rereplication after hydroxyurea treatment: implications for gene amplification. Chromosoma (1986) 0.81

Potentiation of DNA damage by inhibition of poly(ADP-ribosyl)ation: a test of the hypothesis for random nuclease action. Exp Cell Res (1992) 0.81

Perpetuating radiation-induced chromosomal instability. Radiat Oncol Investig (1997) 0.81

Using superoxide dismutase/catalase mimetics to manipulate the redox environment of neural precursor cells. Radiat Prot Dosimetry (2006) 0.81

No evidence for a low linear energy transfer adaptive response in irradiated RKO cells. Radiat Prot Dosimetry (2011) 0.81

Potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced cytotoxicity in 9L cells by pretreatment with 6-thioguanine. Biochem Pharmacol (1985) 0.80

Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity. Somat Cell Mol Genet (1990) 0.80

Poly(ADP-ribose) synthesis is involved in the toxic effects of alkylating agents but does not regulate DNA repair. Mutat Res (1985) 0.80

DNA synthesis on discontinuous templates by human DNA polymerases: implications for non-homologous DNA recombination. Nucleic Acids Res (1998) 0.80

Sister chromatid exchange in cigarette smokers. Hum Genet (1980) 0.80

Synthesis of alpha 2-macroglobulin by bovine adrenal cortical cell cultures. Am J Physiol (1989) 0.79

Neurotoxicity of glycidamide, an acrylamide metabolite, following intraperitoneal injections in rats. J Toxicol Environ Health (1993) 0.79

A comparison of induced sister chromatid exchange levels in Chinese hamster ovary cells and cultured human lymphocytes. Environ Mutagen (1982) 0.79

Induced sister chromatid exchange frequency is not increased in homogeneously staining regions that contain amplified genes. Cancer Genet Cytogenet (1987) 0.79

Modelling the formation of polycentric chromosome aberrations. Int J Radiat Biol (1992) 0.79

Both cross-links and monoadducts induced in DNA by psoralens can lead to sister chromatid exchange formation. Exp Cell Res (1991) 0.79

X irradiation and sister chromatid exchange in cultured human lymphocytes. Environ Mutagen (1980) 0.79

Chlorpyrifos oxon interacts with the mammalian multidrug resistance protein, P-glycoprotein. J Toxicol Environ Health (1996) 0.79

Inhibition of calcium uptake, sodium uptake, and catecholamine secretion by methoxyverapamil (D600) in primary cultures of adrenal medulla cells. J Neurochem (1983) 0.79

The evolution of chromosomal instability in Chinese hamster cells: a changing picture? Int J Radiat Biol (1998) 0.79

Analysis of restriction enzyme-induced chromosomal aberrations by fluorescence in situ hybridization. Environ Mol Mutagen (1993) 0.79

The effects of beta-radiation on sister-chromatid exchanges in cultured human lymphocytes. Mutat Res (1979) 0.78

The role of poly(ADP-ribose) synthesis in toxicity and repair of DNA damage. Pharmacol Ther (1985) 0.78

Effects of 3-aminobenzamide on DNA synthesis and cell cycle progression in Chinese hamster ovary cells. Exp Cell Res (1983) 0.78

Measurement of sister chromatid exchanges and their relationship to DNA damage, repair and cell killing. Pharmacol Ther (1989) 0.78

Delayed repair of DNA single-strand breaks does not increase cytogenetic damage. Int J Radiat Biol Relat Stud Phys Chem Med (1985) 0.78

Induction of sister chromatid exchange by 3-aminobenzamide is independent of bromodeoxyuridine. Cytogenet Cell Genet (1984) 0.78

Occurrence of 1st division metaphases in human lymphocyte cultures. Hum Genet (1978) 0.78

The nucleus is the target for radiation-induced chromosomal instability. Radiat Res (1998) 0.78

Effect of 3-aminobenzamide on sister chromatid exchange frequency in X-irradiated cells. Radiat Res (1983) 0.78

An apparent cluster of aplastic anemia in a small population of teenagers. Arch Intern Med (1985) 0.77