|
1
|
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype.
|
Nat Neurosci
|
2000
|
5.53
|
|
2
|
Photoactivated gamma-secretase inhibitors directed to the active site covalently label presenilin 1.
|
Nature
|
2000
|
4.12
|
|
3
|
2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor.
|
Bioorg Med Chem Lett
|
2000
|
4.03
|
|
4
|
L-685,458, an aspartyl protease transition state mimic, is a potent inhibitor of amyloid beta-protein precursor gamma-secretase activity.
|
Biochemistry
|
2000
|
2.36
|
|
5
|
Nicardipine infusion for the prevention of radial artery spasm during myocardial revascularization.
|
J Cardiothorac Vasc Anesth
|
1998
|
2.01
|
|
6
|
Two-stage treatment with preoperative endoscopic retrograde cholangiopancreatography (ERCP) compared with single-stage treatment with intraoperative ERCP for patients with symptomatic cholelithiasis with possible choledocholithiasis.
|
Endoscopy
|
2006
|
1.61
|
|
7
|
Endoscopic treatment of postoperative fistulas resistant to conservative management using biological fibrin glue.
|
Endoscopy
|
2002
|
1.22
|
|
8
|
Perforation of the globe during strabismus surgery.
|
Arch Ophthalmol
|
1970
|
1.05
|
|
9
|
Neovascular glaucoma after helium ion irradiation for uveal melanoma.
|
Ophthalmology
|
1986
|
0.93
|
|
10
|
Neural networks with a continuous squashing function in the output are universal approximators.
|
Neural Netw
|
2000
|
0.90
|
|
11
|
3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists.
|
J Med Chem
|
2001
|
0.90
|
|
12
|
Pharmacological knock-down of the presenilin 1 heterodimer by a novel gamma -secretase inhibitor: implications for presenilin biology.
|
J Biol Chem
|
2001
|
0.87
|
|
13
|
Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.
|
J Med Chem
|
1999
|
0.87
|
|
14
|
3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists.
|
J Med Chem
|
1999
|
0.84
|
|
15
|
N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.
|
J Med Chem
|
2001
|
0.82
|
|
16
|
Are artificial neural networks black boxes?
|
IEEE Trans Neural Netw
|
1997
|
0.81
|
|
17
|
Treatment of left colon neoplasic obstruction by placement of self-expandable stents.
|
Rev Esp Enferm Dig
|
2001
|
0.78
|
|
18
|
Role of heme oxygenase/carbon monoxide pathway on the vascular response to noradrenaline in portal hypertensive rats.
|
Clin Exp Pharmacol Physiol
|
2005
|
0.77
|
|
19
|
Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors.
|
J Med Chem
|
1993
|
0.77
|
|
20
|
Single-stage treatment with intraoperative ERCP: management of patients with possible choledocholithiasis and gallbladder in situ in a non-tertiary Spanish hospital.
|
Surg Endosc
|
2011
|
0.77
|
|
21
|
Study of interaction between aspartic acid and silver by surface-enhanced Raman scattering on H(2)O and D(2)O sols.
|
Biopolymers
|
2001
|
0.76
|
|
22
|
[Conservative management of severe esophageal complication with fibrin glue (tissucol)].
|
Rev Esp Enferm Dig
|
2000
|
0.75
|
|
23
|
Chromone-3-carboxylic acid as a potential electron scavenger: a surface-enhanced Raman scattering study.
|
Phys Chem Chem Phys
|
2010
|
0.75
|
|
24
|
[The critical record: the registry system in consultation on demand].
|
Aten Primaria
|
1993
|
0.75
|
|
25
|
[Esophageal perforation and postoperative fistulae of the upper digestive tract treated endoscopically with the application of Tissucol].
|
Gastroenterol Hepatol
|
2000
|
0.75
|
|
26
|
2,7-diazabicyclo[3.3.0]octanes as novel h5-HT receptor agonists.
|
Bioorg Med Chem Lett
|
1999
|
0.75
|
|
27
|
The electronic structure of metal-molecule hybrids in charged interfaces: surface-enhanced Raman selection rules derived from plasmon-like resonances.
|
Phys Chem Chem Phys
|
2014
|
0.75
|
|
28
|
[Rifampicin as a cause of acute pancreatitis].
|
Rev Esp Enferm Dig
|
2000
|
0.75
|
|
29
|
[Hematopoiesis and liver cirrhosis].
|
Rev Esp Enferm Apar Dig
|
1970
|
0.75
|
|
30
|
Solid-phase synthesis of 2,3-disubstituted indoles: discovery of a novel, high-affinity, selective h5-HT2A antagonist.
|
Bioorg Med Chem Lett
|
2000
|
0.75
|
|
31
|
[ERCP in the diagnosis of delayed rupture of the gallbladder].
|
Gastroenterol Hepatol
|
2002
|
0.75
|
|
32
|
Parallel synthesis of 3-aryloxy-2-propanolamines and evaluation as dual affinity 5-HT(1A) and 5-HT re-uptake ligands.
|
Bioorg Med Chem Lett
|
1999
|
0.75
|
|
33
|
Quantitative modifications induced by angiotensin II on rat bile secretion.
|
Regul Pept
|
1994
|
0.75
|
|
34
|
[Treatment of inoperable malignant gastric stenosis with self-expanding prosthesis].
|
Gastroenterol Hepatol
|
1999
|
0.75
|