Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model.

PubWeight™: 1.59‹?› | Rank: Top 4%

🔗 View Article (PMID 11136451)

Published in Mol Microbiol on January 01, 2001

Authors

P J Wilderman1, A I Vasil, Z Johnson, M L Vasil

Author Affiliations

1: Department of Microbiology, Campus Box B-175, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA.

Articles citing this

Global transposon mutagenesis and essential gene analysis of Helicobacter pylori. J Bacteriol (2004) 3.25

Type VI secretion system effectors: poisons with a purpose. Nat Rev Microbiol (2014) 2.43

Whole-genome sequence variation among multiple isolates of Pseudomonas aeruginosa. J Bacteriol (2003) 2.41

Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin. Proc Natl Acad Sci U S A (2004) 2.31

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature (2013) 2.11

Involvement of the twin-arginine translocation system in protein secretion via the type II pathway. EMBO J (2001) 2.05

Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and comparative genomics of rhizobia. Genome Res (2008) 1.71

Phospholipase D: enzymology, functionality, and chemical modulation. Chem Rev (2011) 1.66

H-NS family members function coordinately in an opportunistic pathogen. Proc Natl Acad Sci U S A (2008) 1.63

Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis. Infect Immun (2010) 1.54

The accessory genome of Pseudomonas aeruginosa. Microbiol Mol Biol Rev (2010) 1.53

The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase. Proc Natl Acad Sci U S A (2004) 1.33

Transcriptome analysis of Pseudomonas aeruginosa after interaction with human airway epithelial cells. Infect Immun (2004) 1.29

Genetically distinct pathways guide effector export through the type VI secretion system. Mol Microbiol (2014) 1.20

Genome structure in the vole bacillus, Mycobacterium microti, a member of the Mycobacterium tuberculosis complex with a low virulence for humans. Microbiology (2004) 1.06

Pseudomonas aeruginosa synthesizes phosphatidylcholine by use of the phosphatidylcholine synthase pathway. J Bacteriol (2002) 1.04

Inhibition of chlamydiae by primary alcohols correlates with the strain-specific complement of plasticity zone phospholipase D genes. Infect Immun (2006) 1.04

Histidine-containing phosphotransfer protein-B (HptB) regulates swarming motility through partner-switching system in Pseudomonas aeruginosa PAO1 strain. J Biol Chem (2011) 1.00

Use of suppression-subtractive hybridization to identify genes in the Burkholderia cepacia complex that are unique to Burkholderia cenocepacia. J Bacteriol (2005) 0.96

Pseudomonas aeruginosa AES-1 exhibits increased virulence gene expression during chronic infection of cystic fibrosis lung. PLoS One (2011) 0.91

Divergent control of two type VI secretion systems by RpoN in Pseudomonas aeruginosa. PLoS One (2013) 0.91

Phospholipase D promotes Arcanobacterium haemolyticum adhesion via lipid raft remodeling and host cell death following bacterial invasion. BMC Microbiol (2010) 0.89

An rhs gene linked to the second type VI secretion cluster is a feature of the Pseudomonas aeruginosa strain PA14. J Bacteriol (2013) 0.82

The T6SSs of Pseudomonas aeruginosa Strain PAO1 and Their Effectors: Beyond Bacterial-Cell Targeting. Front Cell Infect Microbiol (2016) 0.81

Biochemical characterization of a Pseudomonas aeruginosa phospholipase D. Biochemistry (2015) 0.78

The nptA gene of Vibrio cholerae encodes a functional sodium-dependent phosphate cotransporter homologous to the type II cotransporters of eukaryotes. J Bacteriol (2002) 0.78

Pseudomonas aeruginosa Genome Evolution in Patients and under the Hospital Environment. Pathogens (2014) 0.78

Discovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes. ACS Chem Biol (2014) 0.77

Bacterial Sphingomyelinases and Phospholipases as Virulence Factors. Microbiol Mol Biol Rev (2016) 0.76

prbA, a gene coding for an esterase hydrolyzing parabens in enterobacter cloacae and Enterobacter gergoviae strains. J Bacteriol (2002) 0.75

Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection. BMC Genomics (2015) 0.75

Bacterial type 6 secreted phospholipases play family feud. Cell Host Microbe (2013) 0.75

Articles by these authors

DNA fingerprinting by pulsed field gel electrophoresis and ribotyping to distinguish Pseudomonas cepacia isolates from a nosocomial outbreak. J Clin Microbiol (1991) 4.20

Studies on toxinogenesis in Vibrio cholerae. I. Isolation of mutants with altered toxinogenicity. J Infect Dis (1974) 4.02

Effect of iron on yields of exotoxin A in cultures of Pseudomonas aeruginosa PA-103. Infect Immun (1978) 4.01

Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (1984) 3.98

Characterization and use of a DNA probe as an epidemiological marker for Pseudomonas aeruginosa. J Infect Dis (1987) 3.79

Randomised controlled trial of general practitioner versus usual medical care in an urban accident and emergency department: process, outcome, and comparative cost. BMJ (1996) 3.76

Structure-activity relationships of an exotoxin of Pseudomonas aeruginosa. Infect Immun (1977) 3.63

Identification and characterization of Campylobacter jejuni outer membrane proteins. Infect Immun (1983) 3.24

Studies on toxinogenesis in Vibrio cholerae. III. Characterization of nontoxinogenic mutants in vitro and in experimental animals. J Clin Invest (1975) 3.12

Incidence of exotoxin production by Pseudomonas species. Infect Immun (1977) 3.08

Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes. Proc Natl Acad Sci U S A (1996) 2.71

Coordinate regulation of siderophore and exotoxin A production: molecular cloning and sequencing of the Pseudomonas aeruginosa fur gene. J Bacteriol (1993) 2.69

Studies of phospholipase C (heat-labile hemolysin) in Pseudomonas aeruginosa. Infect Immun (1981) 2.59

Regulation of protein function by glycosaminoglycans--as exemplified by chemokines. Annu Rev Biochem (2005) 2.57

Quantitative measurements of cholera enterotoxin in cultures of toxinogenic wild-type and nontoxinogenic mutant strains of Vibrio cholerae by using a sensitive and specific reversed passive hemagglutination assay for cholera enerotoxin. Infect Immun (1978) 2.55

Molecular studies of Pseudomonas exotoxin A gene. Infect Immun (1986) 2.54

Conjugal transfer of a chromosomal gene determining production of enterotoxin in vibrio cholerae. Science (1975) 2.47

Cloning and characterization of the katB gene of Pseudomonas aeruginosa encoding a hydrogen peroxide-inducible catalase: purification of KatB, cellular localization, and demonstration that it is essential for optimal resistance to hydrogen peroxide. J Bacteriol (1995) 2.21

Nucleotide sequence and expression of a phosphate-regulated gene encoding a secreted hemolysin of Pseudomonas aeruginosa. J Bacteriol (1986) 2.18

Rapid and sensitive method for evaluating Pseudomonas aeruginosa virulence factors during corneal infections in mice. Infect Immun (1995) 2.17

Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa. Microbiology (2000) 2.16

Role of the Pseudomonas aeruginosa oxyR-recG operon in oxidative stress defense and DNA repair: OxyR-dependent regulation of katB-ankB, ahpB, and ahpC-ahpF. J Bacteriol (2000) 2.11

Bacterioferritin A modulates catalase A (KatA) activity and resistance to hydrogen peroxide in Pseudomonas aeruginosa. J Bacteriol (1999) 2.09

Involvement of the twin-arginine translocation system in protein secretion via the type II pathway. EMBO J (2001) 2.05

Cloning and characterization of the Pseudomonas aeruginosa sodA and sodB genes encoding manganese- and iron-cofactored superoxide dismutase: demonstration of increased manganese superoxide dismutase activity in alginate-producing bacteria. J Bacteriol (1993) 2.03

Role of the ferric uptake regulator of Pseudomonas aeruginosa in the regulation of siderophores and exotoxin A expression: purification and activity on iron-regulated promoters. J Bacteriol (1995) 2.01

Campylobacter jejuni outer membrane proteins are antigenic for humans. Infect Immun (1984) 1.99

Genetic mapping of mutations in independently isolated nontoxinogenic mutants of Vibrio cholerae. Infect Immun (1978) 1.98

Pseudomonas aeruginosa fur overlaps with a gene encoding a novel outer membrane lipoprotein, OmlA. J Bacteriol (1999) 1.89

Mutations in the hemolytic-phospholipase C operon result in decreased virulence of Pseudomonas aeruginosa PAO1 grown under phosphate-limiting conditions. Infect Immun (1989) 1.87

Pseudomonas aeruginosa: biology, mechanisms of virulence, epidemiology. J Pediatr (1986) 1.85

Regulation of toxA and regA by the Escherichia coli fur gene and identification of a Fur homologue in Pseudomonas aeruginosa PA103 and PA01. Mol Microbiol (1991) 1.83

Phospholipase C (heat-labile hemolysin) of Pseudomonas aeruginosa: purification and preliminary characterization. J Bacteriol (1982) 1.78

Cloning of a phosphate-regulated hemolysin gene (phospholipase C) from Pseudomonas aeruginosa. J Bacteriol (1982) 1.76

Osmoprotectants and phosphate regulate expression of phospholipase C in Pseudomonas aeruginosa. Mol Microbiol (1992) 1.74

Molecular analysis of hemolytic and phospholipase C activities of Pseudomonas cepacia. Infect Immun (1990) 1.73

Development of resistance in Pseudomonas aeruginosa to imipenem, norfloxacin, and ciprofloxacin during therapy: proof provided by typing with a DNA probe. J Infect Dis (1988) 1.72

Studies on toxinogenesis in Vibrio cholerae. II. An vitro test for enterotoxin production. Infect Immun (1974) 1.72

A survey of knowledge and use of folic acid among women of child-bearing age in Dublin. J Public Health Med (1997) 1.72

Pseudomonas aeruginosa cross-colonization and persistence in patients with cystic fibrosis. Use of a DNA probe. Epidemiol Infect (1989) 1.69

Ferric uptake regulator mutants of Pseudomonas aeruginosa with distinct alterations in the iron-dependent repression of exotoxin A and siderophores in aerobic and microaerobic environments. Mol Microbiol (1996) 1.69

Exotoxin A production in Pseudomonas aeruginosa requires the iron-regulated pvdS gene encoding an alternative sigma factor. Mol Microbiol (1996) 1.65

Molecular comparison of a nonhemolytic and a hemolytic phospholipase C from Pseudomonas aeruginosa. J Bacteriol (1990) 1.65

Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. J Appl Physiol (1985) (1993) 1.64

An operon containing fumC and sodA encoding fumarase C and manganese superoxide dismutase is controlled by the ferric uptake regulator in Pseudomonas aeruginosa: fur mutants produce elevated alginate levels. J Bacteriol (1997) 1.63

Identification of a new phospholipase C activity by analysis of an insertional mutation in the hemolytic phospholipase C structural gene of Pseudomonas aeruginosa. J Bacteriol (1987) 1.60

Temperature-dependent inactivating factor of Pseudomonas aeruginosa exotoxin A. Infect Immun (1976) 1.58

Ferric uptake regulator (Fur) mutants of Pseudomonas aeruginosa demonstrate defective siderophore-mediated iron uptake, altered aerobic growth, and decreased superoxide dismutase and catalase activities. J Bacteriol (1996) 1.56

Characterization of an endoprotease (PrpL) encoded by a PvdS-regulated gene in Pseudomonas aeruginosa. Infect Immun (2001) 1.56

Relation between antibody response to Pseudomonas aeruginosa exoproteins and colonization/infection in patients with cystic fibrosis. Acta Paediatr Scand (1984) 1.54

Physical mapping of virulence-associated genes in Pseudomonas aeruginosa by transverse alternating-field electrophoresis. Infect Immun (1991) 1.53

Genetic and physiological characterization of ohr, encoding a protein involved in organic hydroperoxide resistance in Pseudomonas aeruginosa. J Bacteriol (2001) 1.52

Comparative toxicities of diphtherial toxin and Pseudomonas aeruginosa exotoxin A: evidence for different cell receptors. J Gen Microbiol (1978) 1.52

Analysis of transcription of the exotoxin A gene of Pseudomonas aeruginosa. J Bacteriol (1986) 1.51

A Pseudomonas aeruginosa mutant non-derepressible for orthophosphate-regulated proteins. J Bacteriol (1981) 1.50

Prospective study of serum antibodies to Pseudomonas aeruginosa exoproteins in cystic fibrosis. J Clin Microbiol (1987) 1.49

Isolation and genetic characterization of toxin-deficient mutants of Pseudomonas aeruginosa PAO. J Bacteriol (1981) 1.44

Genetic instability of M protein and serum opacity factor of group A streptocci: evidence suggesting extrachromosomal control. Infect Immun (1975) 1.44

Biochemical and molecular analysis of phospholipase C and phospholipase D activity in mycobacteria. Infect Immun (1996) 1.33

Nucleotide sequence of the Pseudomonas aeruginosa phoB gene, the regulatory gene for the phosphate regulon. J Bacteriol (1990) 1.31

Pseudomonas aeruginosa hemolytic phospholipase C suppresses neutrophil respiratory burst activity. Infect Immun (1999) 1.28

Phenotypic distinctiveness of Staphylococcus aureus strains associated with toxic shock syndrome. Infect Immun (1984) 1.28

Isolation and characterization of a Pseudomonas aeruginosa gene, ptxR, which positively regulates exotoxin A production. Mol Microbiol (1996) 1.27

Phospholipase C regulatory mutation of Pseudomonas aeruginosa that results in constitutive synthesis of several phosphate-repressible proteins. J Bacteriol (1982) 1.23

Nucleotide sequences and expression in Escherichia coli of the in-phase overlapping Pseudomonas aeruginosa plcR genes. J Bacteriol (1987) 1.21

The fur-regulated gene encoding the alternative sigma factor PvdS is required for iron-dependent expression of the LysR-type regulator ptxR in Pseudomonas aeruginosa. J Bacteriol (1998) 1.19

Molecular characterization of mutants affected in the osmoprotectant-dependent induction of phospholipase C in Pseudomonas aeruginosa PAO1. Mol Microbiol (1997) 1.17

The pvc gene cluster of Pseudomonas aeruginosa: role in synthesis of the pyoverdine chromophore and regulation by PtxR and PvdS. J Bacteriol (1999) 1.14

Possible insertion sequences in a mosaic genome organization upstream of the exotoxin A gene in Pseudomonas aeruginosa. J Bacteriol (1990) 1.13

Determinants of folic acid knowledge and use among antenatal women. J Public Health Med (1999) 1.11

East Ireland 1980-1994: epidemiology of neural tube defects. J Epidemiol Community Health (1999) 1.11

Clinical cholera caused by enterotoxigenic Escherichia coli. J Clin Microbiol (1976) 1.10

Phospholipase C: molecular biology and contribution to the pathogenesis of Pseudomonas aeruginosa. Antibiot Chemother (1971) (1991) 1.09

Possible dual function of M protein: resistance to bacteriophage A25 and resistance to phagocytosis by human leukocytes. Infect Immun (1977) 1.08

PlcR1 and PlcR2 are putative calcium-binding proteins required for secretion of the hemolytic phospholipase C of Pseudomonas aeruginosa. Infect Immun (1997) 1.07

Fumarase C activity is elevated in response to iron deprivation and in mucoid, alginate-producing Pseudomonas aeruginosa: cloning and characterization of fumC and purification of native fumC. J Bacteriol (1997) 1.07

Role of Pseudomonas aeruginosa lipase in inflammatory mediator release from human inflammatory effector cells (platelets, granulocytes, and monocytes. Infect Immun (1996) 1.06

Pseudomonas aeruginosa LasB mutant constructed by insertional mutagenesis reveals elastolytic activity due to alkaline proteinase and the LasA fragment. Mol Microbiol (1991) 1.05

Characterization of the 2-ketogluconate utilization operon in Pseudomonas aeruginosa PAO1. Mol Microbiol (2000) 1.04

Effects of single D-amino acid substitutions on disruption of beta-sheet structure and hydrophobicity in cyclic 14-residue antimicrobial peptide analogs related to gramicidin S. J Pept Res (2004) 1.03

The oxygen- and iron-dependent sigma factor pvdS of Pseudomonas aeruginosa is an important virulence factor in experimental infective endocarditis. J Infect Dis (2000) 1.01