S K Spratt

Author PubWeight™ 31.41‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat Genet 1997 4.72
2 Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J Biol Chem 2001 3.38
3 Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene. J Biol Chem 2000 2.85
4 Efficient and stable adeno-associated virus-mediated transduction in the skeletal muscle of adult immunocompetent mice. Hum Gene Ther 1997 2.09
5 Cloning, mapping, and expression of genes involved in the fatty acid-degradative multienzyme complex of Escherichia coli. J Bacteriol 1984 1.66
6 Characterization of intrastriatal recombinant adeno-associated virus-mediated gene transfer of human tyrosine hydroxylase and human GTP-cyclohydrolase I in a rat model of Parkinson's disease. J Neurosci 1998 1.59
7 Prolonged production of NADPH oxidase-corrected granulocytes after gene therapy of chronic granulomatous disease. Proc Natl Acad Sci U S A 1997 1.48
8 Isolation and genetic characterization of Escherichia coli mutants defective in propionate metabolism. J Bacteriol 1981 1.27
9 Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc Natl Acad Sci U S A 1997 1.26
10 Cotransformation of a serum resistance phenotype with genes for arginine biosynthesis in Neisseria gonorrhoeae. Infect Immun 1980 1.22
11 Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease. Blood 1997 1.16
12 Transduction of primitive human hematopoietic cells with recombinant adenovirus vectors. Blood 1996 1.11
13 Regulation of gene expression in vivo following transduction by two separate rAAV vectors. Nat Biotechnol 1998 1.09
14 Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration. Exp Neurol 1999 1.06
15 Amphotropic or gibbon ape leukemia virus retrovirus binding and transduction correlates with the level of receptor mRNA in human hematopoietic cell lines. Blood Cells Mol Dis 1997 0.89
16 Neuroprotection using gene therapy to induce vascular endothelial growth factor-A expression. Gene Ther 2009 0.86
17 Selective uptake and sustained expression of AAV vectors following subcutaneous delivery. J Gene Med 2000 0.83
18 In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via coexpression of GTPcyclohydrolase I with tyrosine hydroxylase. Exp Neurol 1998 0.81
19 Properties of glycosylated and non-glycosylated human recombinant IGF binding protein-3 (IGFBP-3). Growth Regul 1993 0.81
20 Long-term restoration of striatal L-aromatic amino acid decarboxylase activity using recombinant adeno-associated viral vector gene transfer in a rodent model of Parkinson's disease. Neuroscience 1999 0.79
21 Retroviral particles produced from a stable human-derived packaging cell line transduce target cells with very high efficiencies. Hum Gene Ther 1997 0.77