1
|
Mechanism-based design of a protein kinase inhibitor.
|
Nat Struct Biol
|
2001
|
2.13
|
2
|
Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes.
|
J Biol Chem
|
1984
|
1.62
|
3
|
Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose.
|
J Biol Chem
|
1985
|
1.20
|
4
|
Purification, identification, and properties of a Saccharomyces cerevisiae oleate-activated upstream activating sequence-binding protein that is involved in the activation of POX1.
|
J Biol Chem
|
1996
|
1.18
|
5
|
Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity.
|
J Biol Chem
|
1997
|
1.16
|
6
|
Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes.
|
J Biol Chem
|
1986
|
1.16
|
7
|
Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK(1) cells.
|
J Biol Chem
|
2000
|
1.14
|
8
|
Stat5 is a physiological substrate of the insulin receptor.
|
Proc Natl Acad Sci U S A
|
1997
|
1.08
|
9
|
Monovalent avidin affinity columns.
|
Methods Enzymol
|
1990
|
1.04
|
10
|
Effect of phenylarsine oxide on insulin-dependent protein phosphorylation and glucose transport in 3T3-L1 adipocytes.
|
J Biol Chem
|
1987
|
1.04
|
11
|
Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome".
|
J Biol Chem
|
1998
|
1.03
|
12
|
Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism.
|
J Biol Chem
|
2000
|
1.02
|
13
|
The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase.
|
Nucleic Acids Res
|
1999
|
0.99
|
14
|
Identification and partial purification of the insulin-responsive glucose transporter from 3T3-L1 adipocytes.
|
Biochim Biophys Acta
|
1986
|
0.93
|
15
|
Kinetic evidence for activating and non-activating components of autophosphorylation of the insulin receptor protein kinase.
|
Biochem Biophys Res Commun
|
1986
|
0.91
|
16
|
A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo.
|
Diabetes
|
2001
|
0.91
|
17
|
Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression.
|
Mol Cell Biol
|
1995
|
0.91
|
18
|
Activation of the insulin receptor's kinase domain changes the rate-determining step of substrate phosphorylation.
|
Biochemistry
|
2001
|
0.90
|
19
|
Multiple activation loop conformations and their regulatory properties in the insulin receptor's kinase domain.
|
J Biol Chem
|
2001
|
0.90
|
20
|
Cis-autophosphorylation of juxtamembrane tyrosines in the insulin receptor kinase domain.
|
Biochemistry
|
1997
|
0.87
|
21
|
Binding of insulin to solubilized insulin receptor from human placenta. Evidence for a single class of noninteracting binding sites.
|
J Biol Chem
|
1983
|
0.86
|
22
|
Conformational changes in the activation loop of the insulin receptor's kinase domain.
|
Protein Sci
|
1999
|
0.86
|
23
|
Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.
|
Metabolism
|
1994
|
0.85
|
24
|
A binding site for multiple transcriptional activators in the fushi tarazu proximal enhancer is essential for gene expression in vivo.
|
Mol Cell Biol
|
1998
|
0.85
|
25
|
Phosphorylation of myosin regulatory light chains by the molluscan twitchin kinase.
|
Eur J Biochem
|
1995
|
0.83
|
26
|
Autophosphorylation dependent destabilization of the insulin receptor kinase domain: tryptophan-1175 reports changes in the catalytic cleft.
|
Biochemistry
|
1999
|
0.83
|
27
|
Lysozyme degradation by the bovine multicatalytic proteinase complex (proteasome): evidence for a nonprocessive mode of degradation.
|
Biochemistry
|
1999
|
0.82
|
28
|
Probing the catalytic mechanism of the insulin receptor kinase with a tetrafluorotyrosine-containing peptide substrate.
|
J Biol Chem
|
2000
|
0.82
|
29
|
Partial activation of the insulin receptor kinase domain by juxtamembrane autophosphorylation.
|
Biochemistry
|
1998
|
0.81
|
30
|
A simple quantitative assay of 125I-labeled alpha-bungarotoxin binding to soluble and membrane-bound acetylcholine receptor protein.
|
Anal Biochem
|
1977
|
0.80
|
31
|
Environments of the four tryptophans in the extracellular domain of human tissue factor: comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein.
|
Biophys J
|
1995
|
0.80
|
32
|
Post-translational processing and activation of insulin and EGF proreceptors.
|
Biochimie
|
1986
|
0.79
|
33
|
Receptor affinity chromatography.
|
Ann N Y Acad Sci
|
1985
|
0.78
|
34
|
Posttranslational processing of the insulin proreceptor.
|
Curr Top Cell Regul
|
1985
|
0.76
|
35
|
Conformational states of the insulin receptor.
|
Biochem Biophys Res Commun
|
1988
|
0.76
|
36
|
A tyrosine kinase assay using reverse-phase high-performance liquid chromatography.
|
Anal Biochem
|
1997
|
0.76
|
37
|
Intrasteric inhibition of ATP binding is not required to prevent unregulated autophosphorylation or signaling by the insulin receptor.
|
Mol Cell Biol
|
2001
|
0.75
|
38
|
Phenylarsine oxide inhibits insulin activation of phosphatidylinositol 3'-kinase.
|
Biochem Biophys Res Commun
|
1997
|
0.75
|
39
|
The native alpha 2 beta 2 tetramer is the only subunit structure of the insulin receptor in intact cells and purified receptor preparations.
|
Arch Biochem Biophys
|
1991
|
0.75
|