J C Stoclet

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Top papers

Rank Title Journal Year PubWeight™‹?›
1 Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am J Physiol 1990 2.83
2 Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice. EMBO J 1999 2.75
3 Selective inhibition of cyclic nucleotide phosphodiesterases of human, bovine and rat aorta. Biochem Pharmacol 1986 2.04
4 Incubation with endotoxin activates the L-arginine pathway in vascular tissue. Biochem Biophys Res Commun 1990 1.53
5 Nitric oxide production and endothelium-dependent vasorelaxation induced by wine polyphenols in rat aorta. Br J Pharmacol 1997 1.41
6 Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids. Br J Pharmacol 2000 1.25
7 The effect of inhibitors of the L-arginine/nitric oxide pathway on endotoxin-induced loss of vascular responsiveness in anaesthetized rats. Br J Pharmacol 1991 1.23
8 A human tissue-engineered vascular media: a new model for pharmacological studies of contractile responses. FASEB J 2001 1.23
9 Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. J Nutr 1998 1.19
10 Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors. Br J Pharmacol 1991 1.19
11 Inducible but not constitutive production of nitric oxide by vascular smooth muscle cells. Eur J Pharmacol 1991 1.13
12 Calcium handling and purinoceptor subtypes involved in ATP-induced contraction in rat small mesenteric arteries. J Physiol 1996 1.13
13 Endothelial mediated inhibition of contraction and increase in cyclic GMP levels evoked by the alpha-adrenoceptor agonist B-HT 920 in rat isolated aorta. Br J Pharmacol 1984 1.11
14 Evidence that an L-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin. Br J Pharmacol 1991 1.09
15 Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. A study with selective inhibitors. Biochem Pharmacol 1987 1.05
16 Age-related endothelial dysfunction with respect to nitric oxide, endothelium-derived hyperpolarizing factor and cyclooxygenase products. Physiol Res 2000 1.05
17 Participation of endothelium-derived relaxing factor and role of cyclic GMP in inhibitory effects of endothelium on contractile responses elicited by alpha-adrenoceptor agonists in rat aorta. J Cardiovasc Pharmacol 1991 1.04
18 Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery. Br J Pharmacol 1992 1.01
19 Tissue and substrate specificity of inhibition by alkoxy-aryl-lactams of platelet and arterial smooth muscle cyclic nucleotide phosphodiesterases relationship to pharmacological activity. Biochem Biophys Res Commun 1983 0.99
20 Inhibition by papaverine of cGMP and cAMP phosphodiesterases from the rat heart. Biochem Pharmacol 1974 0.98
21 Dependence of endotoxin-induced vascular hyporeactivity on extracellular L-arginine. Br J Pharmacol 1993 0.98
22 L-arginine induces relaxation of small mesenteric arteries from endotoxin-treated rats. Eur J Pharmacol 1992 0.97
23 Mechanism of endothelial nitric oxide-dependent vasorelaxation induced by wine polyphenols in rat thoracic aorta. J Cardiovasc Pharmacol 1999 0.97
24 Involvement of rolipram-sensitive cyclic AMP phosphodiesterase in the regulation of cardiac contraction. J Cardiovasc Pharmacol 1990 0.96
25 Dissociation between endothelium-mediated increases in tissue cGMP levels and modulation of aortic contractile responses. Naunyn Schmiedebergs Arch Pharmacol 1984 0.96
26 Alteration by lipopolysaccharide of the relationship between intracellular calcium levels and contraction in rat mesenteric artery. Br J Pharmacol 1996 0.95
27 Evidence for N-acetylcysteine-sensitive nitric oxide storage as dinitrosyl-iron complexes in lipopolysaccharide-treated rat aorta. Br J Pharmacol 1996 0.94
28 Calmodulin and its role in intracellular calcium regulation. Prog Neurobiol 1987 0.94
29 An ubiquitous protein which regulates calcium-dependent cellular functions and calcium movements. Biochem Pharmacol 1981 0.93
30 Methylene blue increases systemic vascular resistance in human septic shock. Preliminary observations. Intensive Care Med 1992 0.93
31 Bepridil and flunarizine as calmodulin inhibitors. Eur J Pharmacol 1984 0.93
32 Effects of cGMP on calcium handling in ATP-stimulated rat resistance arteries. Am J Physiol 1995 0.92
33 Mechanism of Ca2+ release and entry during contraction elicited by norepinephrine in rat resistance arteries. Am J Physiol 1999 0.92
34 Endotoxin-induced impairment of vascular smooth muscle contractions elicited by different mechanisms. Eur J Pharmacol 1990 0.91
35 Characterization of endothelium-derived relaxing factors released by bradykinin in human resistance arteries. Br J Pharmacol 1997 0.91
36 Hyporeactivity of mesenteric vascular bed in endotoxin-treated rats. Eur J Pharmacol 1996 0.91
37 Flavonoid compounds are potent inhibitors of cyclic AMP phosphodiesterase. Experientia 1978 0.90
38 Age-related decrease of in vitro isoproterenol-induced cyclic AMP accumulation in rat aorta. Eur J Pharmacol 1982 0.90
39 Alterations in calcium stores in aortic myocytes from spontaneously hypertensive rats. Hypertension 1997 0.90
40 Alterations of cyclo-oxygenase products and NO in responses to angiotensin II of resistance arteries from the spontaneously hypertensive rat. Br J Pharmacol 1996 0.89
41 Nitric oxide-related cyclic GMP-independent relaxing effect of N-acetylcysteine in lipopolysaccharide-treated rat aorta. Br J Pharmacol 1998 0.89
42 Characterisation of cyclic nucleotide phosphodiesterases from rat mesenteric artery. Eur J Pharmacol 1991 0.88
43 Functional characterization of postjunctional alpha-adrenoceptors in rat aorta. Eur J Pharmacol 1981 0.88
44 A 16 kDa protein substrate for protein kinase C and its phosphorylation upon stimulation of vasopressin receptors in rat aortic myocytes. Biochem Biophys Res Commun 1987 0.88
45 Insensitivity of calcium-dependent endothelial stimulation in rat isolated aorta to the calcium entry blocker, flunarizine. Br J Pharmacol 1985 0.88
46 Effect of bacterial lipopolysaccharide on function of rat small femoral arteries. Am J Physiol 1994 0.87
47 Cyclic nucleotide phosphodiesterase inhibition and vascular smooth muscle relaxation. Eur J Pharmacol 1972 0.87
48 Exogenous NG-hydroxyl-L-arginine causes nitrite production in vascular smooth muscle cells in the absence of nitric oxide synthase activity. FEBS Lett 1994 0.87
49 Comparison of cyclic nucleotide phosphodiesterase isoforms from rat heart and bovine aorta. Separation and inhibition by selective reference phosphodiesterase inhibitors. Biochem Pharmacol 1988 0.86
50 Involvement of protein kinase C, tyrosine kinases, and Rho kinase in Ca(2+) handling of human small arteries. Am J Physiol Heart Circ Physiol 2000 0.86
51 A pertussis toxin-insensitive calcium influx mediated by neuropeptide Y2 receptors in a human neuroblastoma cell line. J Biol Chem 1994 0.86
52 Effect of dexamethasone on the onset and persistence of vascular hyporeactivity induced by E. coli lipopolysaccharide in rats. Circ Shock 1993 0.86
53 [Does cyclic AMP play a part in the bronchodilator effect of theophylline? (author's transl)]. Bull Eur Physiopathol Respir 1980 0.86
54 Potentiation by neuropeptide Y of vasoconstriction in rat resistance arteries. Br J Pharmacol 1988 0.86
55 Influence of endothelium on induction of the L-arginine-nitric oxide pathway in rat aortas. Am J Physiol 1993 0.85
56 Cytosolic and membrane-bound cyclic nucleotide phosphodiesterases from guinea pig cardiac ventricles. Eur J Pharmacol 1992 0.85
57 Implication of cyclic AMP in the positive inotropic effects of cyclic GMP-inhibited cyclic AMP phosphodiesterase inhibitors on guinea pig isolated left atria. J Cardiovasc Pharmacol 1990 0.85
58 Pharmacological approaches of endothelial nitric oxide-dependent vasorelaxation induced by polyphenols from plant extracts. Methods Enzymol 1999 0.85
59 Subsensitivity of presynaptic adenosine A1-receptors in caudal arteries of spontaneously hypertensive rats. Eur J Pharmacol 1989 0.84
60 Enhancement by neuropeptide Y (NPY) of the dihydropyridine-sensitive component of the response to alpha 1-adrenoceptor stimulation in rat isolated mesenteric arterioles. Br J Pharmacol 1990 0.84
61 Influence of indomethacin on the haemodynamic effects of lipopolysaccharide in rats. Fundam Clin Pharmacol 1996 0.84
62 Effects of methylene blue on blood pressure and reactivity to norepinephrine in endotoxemic rats. J Cardiovasc Pharmacol 1993 0.84
63 Role of cyclic AMP in the prejunctional alpha 2-adrenoceptor modulation of noradrenaline release from the rat tail artery. Naunyn Schmiedebergs Arch Pharmacol 1990 0.84
64 Papaverine, cyclic AMP and the dependence of the rat aorta on extracellular calcium. Eur J Pharmacol 1975 0.84
65 Differential sensitivity to cardiotonic drugs of cyclic AMP phosphodiesterases isolated from canine ventricular and sinoatrial-enriched tissues. J Cardiovasc Pharmacol 1989 0.84
66 Alterations of peripheral blood lymphocyte cyclic AMP and cyclic GMP in untreated patients with hodgkin's disease. Clin Immunol Immunopathol 1983 0.84
67 Isoprenaline induces endothelium-independent relaxation and accumulation of cyclic nucleotides in the rat aorta. Eur J Pharmacol 1994 0.83
68 Effect of vasoactive intestinal polypeptide (VIP) on cyclic AMP level and relaxation in rat isolated aorta. Eur J Pharmacol 1985 0.83
69 Role of adventitial nitric oxide in vascular hyporeactivity induced by lipopolysaccharide in rat aorta. Br J Pharmacol 1998 0.83
70 Prejunctional opioid mu-receptors and adenosine A1-receptors on the sympathetic nerve endings of the rat tail artery interact with the alpha 2-adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol 1992 0.82
71 Responses of subcultured rat aortic smooth muscle myocytes to vasoactive agents and KCl-induced depolarization. Am J Physiol 1991 0.82
72 Hyperosmolarity enhances smooth muscle contractile responses to phenylephrine and partially impairs nitric oxide production in the rat tail artery. J Vasc Res 1995 0.82
73 ANG II receptor expression and function during phenotypic modulation of rat aortic smooth muscle cells. Am J Physiol 1994 0.82
74 Cyclic AMP-dependent phosphorylation of a 16 kDa protein in a plasma membrane-enriched fraction of rat aortic myocytes. FEBS Lett 1985 0.82
75 Neuropeptide Y increases force development through a mechanism that involves calcium entry in resistance arteries. J Vasc Res 1994 0.82
76 Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues. J Med Chem 1989 0.81
77 Role of endothelial nitric oxide in the response to angiotensin II of small mesenteric arteries of the rat. J Vasc Res 1996 0.81
78 Adventitia-derived nitric oxide in rat aortas exposed to endotoxin: cell origin and functional consequences. Am J Physiol Heart Circ Physiol 2000 0.81
79 Triggering role of nitric oxide in the delayed protective effect of monophosphoryl lipid A in rat heart. Br J Pharmacol 1999 0.81
80 Age related changes in cardiac and aortic phosphodiesterase activities in normotensive and hypertensive rats. Biochem Pharmacol 1979 0.81
81 Stereoselective blockade of alpha-adrenoceptors by berbine derivatives. Arzneimittelforschung 1988 0.81
82 Comparative effects of calmodulin inhibitors on calmodulin's hydrophobic sites and on the activation of cyclic nucleotide phosphodiesterase by calmodulin. Biochem Pharmacol 1987 0.80
83 Effects of cyclic GMP and analogues on neurogenic transmission in the rat tail artery. Br J Pharmacol 1994 0.80
84 Effect of papaverine on cyclic nucleotide levels in the isolated rat aorta. Eur J Pharmacol 1977 0.80
85 An L-arginine-derived factor mediates endotoxin-induced vascular hyposensitivity to calcium. Eur J Pharmacol 1990 0.80
86 Pertussis toxin abolishes the effect of neuropeptide Y on rat resistance arteriole contraction. Am J Physiol 1990 0.80
87 Effects of cyclic AMP and analogues on neurogenic transmission in the rat tail artery. Br J Pharmacol 1994 0.80
88 Aortic smooth muscle cells are able to convert angiotensin I to angiotensin II. Biochem Biophys Res Commun 1990 0.79
89 Effects of bepridil and of its quaternary derivative on rat tail artery. Eur J Pharmacol 1986 0.79
90 Alpha-adrenoceptor antagonistic and calcium antagonistic effects of nicergoline in the rat isolated aorta. Eur J Pharmacol 1986 0.79
91 Vasoconstrictor effects of various neuropeptide Y analogues on the rat tail artery in the presence of phenylephrine. Br J Pharmacol 1993 0.79
92 Inducible NO synthase activity in blood vessels and heart: new insight into cell origin and consequences. Physiol Res 2000 0.79
93 Characterization of two distinct alpha-adrenoceptor binding sites in smooth muscle cell membranes from rat and bovine aorta. Naunyn Schmiedebergs Arch Pharmacol 1985 0.79
94 Decrease of calcium turnover during the onset of mineralocorticoid hypertension in the rat. Life Sci 1975 0.79
95 Separation of three cyclic-nucleotide-phosphodiesterases from bovine aorta. Biochem Biophys Res Commun 1978 0.79
96 Ageing as a factor governing the effect of isoproterenol on the cyclic AMP level in isolated aorta from spontaneously hypertensive and normotensive rats. Eur J Pharmacol 1983 0.78
97 Changes in angiotensin II receptor density and calcium handling during proliferation in SHR aortic myocytes. Am J Physiol 1996 0.78
98 Effect of lipopolysaccharide treatment on neurogenic contraction and noradrenaline release in rat arteries. Fundam Clin Pharmacol 2001 0.78
99 Effect of parathyroid hormone and antagonist on aortic cAMP levels. Can J Physiol Pharmacol 1987 0.78
100 Modulation by endothelium of contractile responses in rat aorta in absence and presence of flunarizine. Br J Pharmacol 1985 0.78
101 Phorbol ester inhibition of vasopressin-induced calcium efflux from cultured rat aortic myocytes. FEBS Lett 1986 0.78
102 Cardiac cGMP-stimulated cyclic nucleotide phosphodiesterases: effects of cGMP analogues and drugs. Eur J Pharmacol 1991 0.78
103 Age-related differences in cyclic AMP metabolism and their consequences on relaxation induced by isoproterenol and phosphodiesterase inhibitors in rat isolated aorta. Mech Ageing Dev 1990 0.78
104 Interaction of calmodulin and calcium antagonists with [3H]diltiazem and [3H]nitrendipine binding sites. J Cardiovasc Pharmacol 1988 0.78
105 On the mechanism of papaverine action on the control of vascular smooth muscle contractile activity by extracellular calcium. J Pharm Pharmacol 1971 0.78
106 Effect of endotoxin on circulating cyclic GMP in the rat. Eur J Pharmacol 1992 0.78
107 Role of endothelium on the effects of neuropeptide Y in mesenteric resistance arteries of spontaneously hypertensive and Wistar-Kyoto normotensive rats. J Pharmacol Exp Ther 1991 0.77
108 Effects of losartan on contractile responses of conductance and resistance arteries from rats. J Cardiovasc Pharmacol 1995 0.77
109 Interactions of calmodulin antagonists with calcium antagonists binding sites. Eur J Pharmacol 1991 0.77
110 High sensitivity of hypertensive aortic myocytes to norepinephrine and angiotensin. Am J Physiol 1993 0.77
111 High-affinity bradykinin B2 binding sites sensitive to guanine nucleotides in bovine aortic endothelial cells. Eur J Pharmacol 1991 0.77
112 Quantitative method for the study of the morphological changes induced by vasoactive agents in single aortic myocytes grown in primary cultures. Lab Invest 1987 0.77
113 [Utilization of a multiparametric technique for analysis of specificity of different inhibitors of various forms of cyclic nucleotide phosphodiesterases]. Pharmazie 1992 0.77
114 Temporal relationships between levels of circulating NO derivatives, vascular NO production and hyporeactivity to noradrenaline induced by endotoxin in rats. Cardiovasc Res 1995 0.77
115 Differences in myocyte subpopulations from segments of the thoracic aorta and their modifications with age and hypertension in the rat. Cell Tissue Res 1987 0.76
116 Involvement of bradykinin and nitric oxide in the early hemodynamic effects of lipopolysaccharide in rats. Shock 1995 0.76
117 Possible mechanism of nitric oxide production from N(G)-hydroxy-L-arginine or hydroxylamine by superoxide ion. Int J Biochem Cell Biol 1996 0.76
118 Increase in serum NG-hydroxy-L-arginine in rats treated with bacterial lipopolysaccharide. Eur J Pharmacol 1995 0.76
119 A comparison of cyclic AMP signaling system in rat aortic myocytes in primary culture and aorta. Lab Invest 1989 0.76
120 Diphenylalkylamine calcium antagonists interact with alpha-adrenoceptor binding sites in aortic membranes. Eur J Pharmacol 1985 0.76
121 Use of vascular smooth-muscle single cell suspensions for rapid cell number determination in rat thoracic aorta media layer. Cell Biol Int Rep 1982 0.76
122 Smooth muscle cell hypertrophy and hyperplasia in the thoracic aorta of spontaneously hypertensive rats. Cell Biol Int Rep 1984 0.76
123 Cyclic AMP and cyclic GMP phosphodiesterase activities in Hodgkin's disease lymphocytes. Int J Immunopharmacol 1987 0.76
124 Age-related changes of in vivo beta-adrenergic responsiveness in normotensive and spontaneously hypertensive rats. Eur J Pharmacol 1984 0.76
125 Evolution of aortic and cardiac cyclic AMP phosphodiesterase during the onset of mineralpcorticoid hypertension in the rat [proceedings]. Br J Pharmacol 1976 0.75
126 Normal peripheral-blood lymphocyte cAMP and cGMP resting levels in untreated patients with mycosis fungoides. Arch Dermatol Res 1985 0.75
127 Vascular relaxation and cyclic guanosine monophosphate in a rat model of high output heart failure. Cardiovasc Res 1993 0.75
128 Endothelial and smooth muscle cells from the same rat aorta. In Vitro Cell Dev Biol 1991 0.75
129 Inhibition of 3',5'-AMP phosphodiesterase by biflavonoids and xanthones. Planta Med 1979 0.75
130 [Nicardipine: vascular compliance and development of genetic hypertension in the SHR rat]. J Pharmacol 1984 0.75
131 In vivo decrease of adenylate cyclase responsiveness to isoproterenol in the spontaneously hypertensive rat. Biochem Pharmacol 1981 0.75
132 Further evidence for the existence of a homogenous beta-endorphin-sensitive receptor population in the rat tail artery. Eur J Pharmacol 1988 0.75
133 Effects of inaktin on calcium metabolism in the rat. Fundam Clin Pharmacol 1988 0.75
134 In vivo alteration of calcium turnover induced by reserpine in rat tissues. J Pharm Pharmacol 1980 0.75
135 Modulation of [(3)H]noradrenaline release by endothelin-1 in the rat tail artery. Neurochem Int 1991 0.75
136 [Evolution of calcium metabolism during mineralocorticoid hypertension in the rat]. C R Seances Soc Biol Fil 1973 0.75
137 [Movements of calcium in resting and active muscle in in vitro rats]. J Physiol Suppl (Paris) 1966 0.75
138 Variations in endogenous phosphodiesterase activator content of rat aorta. Eur J Pharmacol 1978 0.75
139 Highly enriched, minimally disrupted plasma membrane vesicles from aortic myocytes grown in primary culture. Biochim Biophys Acta 1984 0.75
140 Adrenomedullary and beta-adrenergic participation in enhanced sympathetic pressor responses of spontaneously hypertensive rats. Eur J Pharmacol 1987 0.75
141 Characterization of cultured rat aortic endothelial cells. J Physiol Paris 1992 0.75
142 [Nitric oxide storage in the cardiovascular system]. Izv Akad Nauk Ser Biol 2002 0.75
143 Different effects of phenylephrine and clonidine on 86Rb efflux and on contraction in the rat caudal artery. Eur J Pharmacol 1984 0.75
144 [Study of the calcium in the aorta, small intestine and uterus in the rat in vivo]. J Physiol (Paris) 1966 0.75
145 Mechanisms of anti-bronchoconstrictive effects of eprozinol. I. In vitro studies. Pharmacology 1981 0.75
146 Age, endothelium and aortic reactivity to calcium in Wistar rat. Life Sci 1993 0.75
147 Cyclic nucleotide phosphodiesterase in the aorta of spontaneously hypertensive rats : variation with age and effect of propranolol. Artery 1980 0.75
148 [Influence of metacorticoid hypertension on sensitivity of the isolated rat aorta to Ba2 ions and to papaverine]. C R Seances Soc Biol Fil 1970 0.75
149 Production of an arginine-derived relaxing factor induced by IFN-gamma plus endotoxin in murine adenocarcinoma EMT 6 cells. Biochem Biophys Res Commun 1990 0.75
150 Mechanical responses of rat vascular smooth muscle cells to rat interferon. J Interferon Res 1986 0.75
151 Immunomodulating effects of a short-term oral treatment with C 1821 in untreated cancer patients: a controlled study. Adv Exp Med Biol 1983 0.75
152 [The role of calcium in the response of isolated rat aorta to norepinephrine and barium]. J Physiol (Paris) 1971 0.75
153 [Arguments in favor of a possible role of calcium in local muscular fatigue]. J Physiol (Paris) 1970 0.75
154 [Calmodulin and the effect of calcium antagonists]. J Pharmacol 1986 0.75
155 Intracellular Ca2+ and force determined simultaneously in isolated resistance arteries. Am J Physiol 1989 0.75
156 [Permanent catheterization of the thoracic aorta. Direct measure of blood pressure, injection of substances, and blood sampling in the waking rat]. J Physiol (Paris) 1973 0.75
157 Nitric oxide generation from extracellularly applied NG-hydroxy-L-arginine in LPS-activated RAW 264 macrophages. Biochim Biophys Acta 1997 0.75
158 Parathyroid hormone effects on calcium metabolism in the rat are impaired by 5-ethyl-5'-(1-methylpropyl)-2-thiobarbiturate (inaktin). Eur J Pharmacol 1981 0.75
159 [Expression of results in studies of vascular biochemical components during the development of the SHR rat]. Paroi Arterielle 1980 0.75
160 [Antagonism between cyclic AMP and calcium on isolated depolarized aorta in the rat]. J Physiol (Paris) 1972 0.75
161 Cationic amino acids inhibit the effects of L-arginine in rat aorta exposed to lipopolysaccharide. Eur J Pharmacol 1993 0.75
162 Vascular smooth muscle cell hypertrophy during maturation in rat thoracic aorta. Volumetric and morphometric studies. Cell Biol Int Rep 1982 0.75