Published in Genetics on February 01, 2001
Functional role of epsilon-tubulin in the assembly of the centriolar microtubule scaffold. J Cell Biol (2002) 1.14
Transgene-mediated post-transcriptional gene silencing is inhibited by 3' non-coding sequences in Paramecium. Nucleic Acids Res (2001) 1.10
A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress. PLoS Pathog (2013) 1.08
C-terminal armadillo repeats are essential and sufficient for association of the plant U-box armadillo E3 ubiquitin ligase SAUL1 with the plasma membrane. J Exp Bot (2010) 0.98
PAK paradox: Paramecium appears to have more K(+)-channel genes than humans. Eukaryot Cell (2003) 0.83
N-ethylmaleimide-sensitive factor is required to organize functional exocytotic microdomains in paramecium. Genetics (2002) 0.80
Nd6p, a novel protein with RCC1-like domains involved in exocytosis in Paramecium tetraurelia. Eukaryot Cell (2005) 0.79
Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila. G3 (Bethesda) (2016) 0.75
An evolutionary balance: conservation vs innovation in ciliate membrane trafficking. Traffic (2016) 0.75
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res (1997) 665.31
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem (1987) 281.19
Genomic sequencing. Proc Natl Acad Sci U S A (1984) 92.36
The Pfam protein families database. Nucleic Acids Res (2000) 42.28
SMART: a web-based tool for the study of genetically mobile domains. Nucleic Acids Res (2000) 17.77
SNAREpins: minimal machinery for membrane fusion. Cell (1998) 16.97
'DNA Strider': a 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers. Nucleic Acids Res (1988) 9.48
The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature (1995) 7.48
Three-dimensional structure of the armadillo repeat region of beta-catenin. Cell (1997) 7.35
The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J (1996) 6.26
A repeating amino acid motif shared by proteins with diverse cellular roles. Cell (1994) 4.56
The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis. Bacteriol Rev (1976) 4.11
Transport-vesicle targeting: tethers before SNAREs. Nat Cell Biol (1999) 3.55
Protein sequence databases. Adv Protein Chem (2000) 2.24
Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene. Genes Dev (1989) 2.17
Vac8p, a vacuolar protein with armadillo repeats, functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole. J Cell Biol (1998) 2.13
Genetic analysis of membrane differentiation in Paramecium. Freeze-fracture study of the trichocyst cycle in wild-type and mutant strains. J Cell Biol (1976) 2.05
Homology-dependent gene silencing in Paramecium. Mol Biol Cell (1998) 1.98
Epigenetic self-regulation of developmental excision of an internal eliminated sequence on Paramecium tetraurelia. Genes Dev (1995) 1.91
SNAREs and SNARE regulators in membrane fusion and exocytosis. Cell Mol Life Sci (1999) 1.82
Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins. J Biol Chem (1990) 1.62
Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase. J Biol Chem (1999) 1.58
Control of exocytotic processes: cytological and physiological studies of trichocyst mutants in Paramecium tetraurelia. J Cell Biol (1981) 1.48
Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. Mol Cell Biol (1991) 1.36
Yeast VSM1 encodes a v-SNARE binding protein that may act as a negative regulator of constitutive exocytosis. Mol Cell Biol (1999) 1.27
YEB3/VAC8 encodes a myristylated armadillo protein of the Saccharomyces cerevisiae vacuolar membrane that functions in vacuole fusion and inheritance. J Cell Sci (1998) 1.23
Genetic approach to regulated exocytosis using functional complementation in Paramecium: identification of the ND7 gene required for membrane fusion. Mol Biol Cell (1997) 1.15
Molecular genetics of regulated secretion in paramecium. Biochimie (2000) 1.12
Cerulenin-resistant mutants of Saccharomyces cerevisiae with an altered fatty acid synthase gene. Mol Gen Genet (1994) 1.09
Genetic analysis of the relationships between the cell surface and the nuclei in Paramecium tetraurella. Genetics (1980) 1.09
Control of membrane fusion in exocytosis. Physiological studies on a Paramecium mutant blocked in the final step of the trichocyst extrusion process. J Cell Biol (1980) 1.08
Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha is associated with the yeast vacuole membrane. J Cell Sci (1998) 1.07
Cell surface complexes ('cortices') isolated from Paramecium tetraurelia cells as a model system for analysing exocytosis in vitro in conjunction with microinjection studies. Biochem J (1990) 1.02
Synchronous exocytosis in Paramecium cells. I. A novel approach. Exp Cell Res (1984) 1.01
Mechanics of membrane fusion. Nat Struct Biol (1998) 0.93
Interactions between genes involved in exocytotic membrane fusion in paramecium. Genetics (1992) 0.89
Exocytosis: SNAREs drum up! Eur J Neurosci (1998) 0.89
Toward cloning genes by complementation in Paramecium. J Neurogenet (1996) 0.89
Regulation of alpha-galactosidase synthesis in Saccharomyces cerevisiae and effect of cerulenin on the secretion of this enzyme. Biochim Biophys Acta (1982) 0.77
Weighted kappa: nominal scale agreement with provision for scaled disagreement or partial credit. Psychol Bull (1968) 20.58
The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry (1976) 15.48
Rubber hands 'feel' touch that eyes see. Nature (1998) 9.13
The Duesberg phenomenon. Science (1994) 8.47
Rotavirus gene structure and function. Microbiol Rev (1989) 6.95
Long-term weight loss and changes in blood pressure: results of the Trials of Hypertension Prevention, phase II. Ann Intern Med (2001) 5.90
[Procreative tourism as a last resort]. Gynecol Obstet Fertil (2006) 5.19
Multifaceted shared care intervention for late life depression in residential care: randomised controlled trial. BMJ (1999) 5.07
An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1988) 4.72
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev (2001) 4.28
Septic shock: pathogenesis. Lancet (1991) 3.99
Implications of small reductions in diastolic blood pressure for primary prevention. Arch Intern Med (1995) 3.71
An epidemiological study of disorders in late childhood and adolescence--I. Age- and gender-specific prevalence. J Child Psychol Psychiatry (1993) 3.54
Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities. Fertil Steril (1995) 3.49
Sterilization patterns in a Northern Canadian population. Can J Public Health (1978) 3.46
Activation of rotavirus RNA polymerase by calcium chelation. Arch Virol (1979) 3.44
Ribonucleic acid polymerase activity associated with purified calf rotavirus. J Gen Virol (1977) 3.40
Use of randomly amplified polymorphic DNA markers to distinguish isolates of Aspergillus fumigatus. J Clin Microbiol (1992) 3.39
A comparison of transurethral surgery with watchful waiting for moderate symptoms of benign prostatic hyperplasia. The Veterans Affairs Cooperative Study Group on Transurethral Resection of the Prostate. N Engl J Med (1995) 3.38
Domestic violence and childhood sexual abuse in HIV-infected women and women at risk for HIV. Am J Public Health (2000) 3.37
Occupational and environmental medicine. Meeting the growing need for clinical services. N Engl J Med (1991) 3.25
Preliminary marked increase in the national organ donation rate in Israel following implementation of a new organ transplantation law. Am J Transplant (2012) 3.22
A clinical and pathological staging system for soft tissue sarcomas. Cancer (1977) 3.19
Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F. EMBO J (1998) 3.16
Decline in sperm counts: an artefact of changed reference range of "normal"? BMJ (1994) 3.09
Isolation of nonsense suppressor mutants in Pseudomonas. J Bacteriol (1976) 3.07
Quantification of agreement in psychiatric diagnosis. A new approach. Arch Gen Psychiatry (1967) 3.05
Use of general practice by intravenous heroin users on a methadone programme. Br J Gen Pract (1992) 3.04
The scientific challenge of hepatitis C. Science (1999) 2.94
Tobacco money lights up a debate. Science (1996) 2.89
Is NIH's crown jewel losing luster? Science (1993) 2.86
Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3. Nat Med (2000) 2.70
Sympathetic skin response--a method of assessing unmyelinated axon dysfunction in peripheral neuropathies. J Neurol Neurosurg Psychiatry (1984) 2.68
Fertility and ageing. Hum Reprod Update (2005) 2.68
Scientists who fund themselves. Science (1998) 2.64
Debate on AIDS origin: Rolling Stone weighs in. Science (1992) 2.60
An Aspergillus fumigatus alkaline protease mutant constructed by gene disruption is deficient in extracellular elastase activity. Mol Microbiol (1992) 2.59
AIDS trials ethics questioned. Science (1997) 2.57
The clinician's illusion. Arch Gen Psychiatry (1984) 2.55
Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria. J Infect Dis (2001) 2.54
Detection of Aspergillus fumigatus by polymerase chain reaction. J Clin Microbiol (1993) 2.51
Role of locus coeruleus in attention and behavioral flexibility. Biol Psychiatry (1999) 2.51
Characterization of virus-like particles produced by the expression of rotavirus capsid proteins in insect cells. J Virol (1994) 2.48
A practice counsellor. J R Coll Gen Pract (1978) 2.47
The detection of Aspergillus spp. by the polymerase chain reaction and its evaluation in bronchoalveolar lavage fluid. Am Rev Respir Dis (1993) 2.46
Diagnosis of major chromosome aneuploidies in human preimplantation embryos. Hum Reprod (1993) 2.45
Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion. EMBO J (2001) 2.43
Purification and characterization of bovine rotavirus cores. J Virol (1982) 2.43
Specific missense mutations in NEMO result in hyper-IgM syndrome with hypohydrotic ectodermal dysplasia. Nat Immunol (2001) 2.42
Conflicting agendas shape NIH. Science (1993) 2.40
Expression of rotavirus VP2 produces empty corelike particles. J Virol (1991) 2.38
Detection of group B and C rotaviruses by polymerase chain reaction. J Clin Microbiol (1991) 2.36
Comorbidity of psychiatric diagnoses in anorexia nervosa. Arch Gen Psychiatry (1991) 2.36
Combining discrepant diagnostic information from multiple sources: are complex algorithms better than simple ones? J Abnorm Child Psychol (1992) 2.30
A comprehensive support program: effect on depression in spouse-caregivers of AD patients. Gerontologist (1995) 2.26
A prospective study of fever in the intensive care unit. Intensive Care Med (1999) 2.24
Analysis of gene expression in single oocytes and embryos by real-time rapid cycle fluorescence monitored RT-PCR. Mol Hum Reprod (1999) 2.24
Two types of astrocytes in cultures of developing rat white matter: differences in morphology, surface gangliosides, and growth characteristics. J Neurosci (1983) 2.18
Clinical gram-positive sepsis: does it fundamentally differ from gram-negative bacterial sepsis? Crit Care Med (1999) 2.15
Birth of infant after transfer of anucleate donor oocyte cytoplasm into recipient eggs. Lancet (1997) 2.13
Share and share alike isn't always the rule in science. Science (1995) 2.07
Preferences for place of death if faced with advanced cancer: a population survey in England, Flanders, Germany, Italy, the Netherlands, Portugal and Spain. Ann Oncol (2012) 2.07
Intracytoplasmic sperm injection: a powerful tool to overcome fertilization failure. Fertil Steril (1996) 2.06
Unexpected antimicrobial effect of statins. J Antimicrob Chemother (2007) 2.05
Corn genome pops out of the pack. Science (1997) 2.05
AIDS research. Keystone's blunt message: 'it's the virus, stupid'. Science (1993) 2.03
TB policy and the ISG's findings. Vet Rec (2007) 2.02
A permutation test for the robust sib-pair linkage method. Ann Hum Genet (1997) 2.02
Preimplantation diagnosis in older patients--but of course! Hum Reprod (1997) 2.01
Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine. J Infect Dis (1998) 2.00
Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol (1986) 1.98
Tobacco industry litigation and the role of government: a public health perspective. Can J Public Health (2001) 1.94
AIDS research. Vaccine studies stymied by shortage of animals. Science (2000) 1.91
Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo. Cell Microbiol (2001) 1.88
Epidemiological aspects of cholera El Tor outbreak in a non-endemic area. Lancet (1971) 1.87
Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis. J Cell Biol (1998) 1.85
An EORTC multicentre prospective survey of invasive aspergillosis in haematological patients: diagnosis and therapeutic outcome. EORTC Invasive Fungal Infections Cooperative Group. J Infect (1998) 1.82
Life-threatening arrhythmias and intravenous cimetidine. Br Med J (1979) 1.81
Three-dimensional structural analysis of recombinant rotavirus-like particles with intact and amino-terminal-deleted VP2: implications for the architecture of the VP2 capsid layer. J Virol (1997) 1.81
Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection. Infect Immun (1999) 1.81
Outcome of preimplantation genetic diagnosis of translocations. Fertil Steril (2000) 1.78
Characterizing criminal careers. Science (1987) 1.78
Induction of anti-phospholipid syndrome in naive mice with mouse lupus monoclonal and human polyclonal anti-cardiolipin antibodies. Proc Natl Acad Sci U S A (1991) 1.77
Potent induction of focused Th1-type cellular and humoral immune responses by RTS,S/SBAS2, a recombinant Plasmodium falciparum malaria vaccine. J Infect Dis (1999) 1.76
Endotoxaemia and serum tumour necrosis factor as prognostic markers in severe acute pancreatitis. Gut (1992) 1.76
Endotoxin removal devices for the treatment of sepsis and septic shock. Lancet Infect Dis (2011) 1.74
Isolation of a human pararotavirus. Virology (1983) 1.73
Accident and emergency services and general practice--conflict or cooperation? Fam Pract (1987) 1.73
I. The moral status of the pre-implantation embryo. Hum Reprod (2001) 1.73
An intervention that delays institutionalization of Alzheimer's disease patients: treatment of spouse-caregivers. Gerontologist (1993) 1.72
Demonstration of size variation of RNA segments between different isolates of calf rotavirus. J Gen Virol (1977) 1.71
Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med (2000) 1.70
Restriction fragment length polymorphisms in isolates of Aspergillus fumigatus probed with part of the intergenic spacer region from the ribosomal RNA gene complex of Aspergillus nidulans. J Gen Microbiol (1990) 1.68
Hamilton Depression Rating Scale. Extracted from Regular and Change Versions of the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry (1981) 1.68
Homology-dependent maternal inhibition of developmental excision of internal eliminated sequences in Paramecium tetraurelia. Mol Cell Biol (1998) 1.67
Are there age and sex differences in the investigation and treatment of heart failure? A population-based study. Br J Gen Pract (2000) 1.67
Three-dimensional echocardiography: in vitro and in vivo validation of left ventricular mass and comparison with conventional echocardiographic methods. J Am Coll Cardiol (1994) 1.67
Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci U S A (1996) 1.66
Genetic studies of temperature-sensitive and nonsense mutants of bacteriophage phi6. Virology (1976) 1.65