J Kimble

Author PubWeight™ 127.83‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans. Dev Biol 1979 8.31
2 glp-1 is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans. Cell 1987 5.07
3 A conserved RNA-binding protein that regulates sexual fates in the C. elegans hermaphrodite germ line. Nature 1997 4.34
4 Alterations in cell lineage following laser ablation of cells in the somatic gonad of Caenorhabditis elegans. Dev Biol 1981 3.61
5 fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegans. Genetics 1988 3.53
6 Gain-of-function mutations of fem-3, a sex-determination gene in Caenorhabditis elegans. Genetics 1987 3.16
7 gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics 1995 2.94
8 NANOS-3 and FBF proteins physically interact to control the sperm-oocyte switch in Caenorhabditis elegans. Curr Biol 1999 2.75
9 Control of the sperm-oocyte switch in Caenorhabditis elegans hermaphrodites by the fem-3 3' untranslated region. Nature 1991 2.74
10 lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans. Development 1994 2.66
11 Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans. Dev Biol 1983 2.60
12 Translational regulation of tra-2 by its 3' untranslated region controls sexual identity in C. elegans. Cell 1993 2.52
13 Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions. Development 1991 2.30
14 Genetic regulation of entry into meiosis in Caenorhabditis elegans. Development 1998 2.28
15 GLP-1 is localized to the mitotic region of the C. elegans germ line. Development 1994 2.25
16 lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H). Development 1996 2.20
17 LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway. Nature 2000 2.17
18 pha-4, an HNF-3 homolog, specifies pharyngeal organ identity in Caenorhabditis elegans. Genes Dev 1998 2.14
19 fog-1, a regulatory gene required for specification of spermatogenesis in the germ line of Caenorhabditis elegans. Genetics 1990 2.06
20 Specification of male development in Caenorhabditis elegans: the fem genes. Dev Biol 1984 1.99
21 The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans. Development 1994 1.85
22 Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo. Cell 1994 1.77
23 The origin and evolution of animal appendages. Proc Natl Acad Sci U S A 1997 1.76
24 Transcript analysis of glp-1 and lin-12, homologous genes required for cell interactions during development of C. elegans. Cell 1989 1.73
25 tra-2 encodes a membrane protein and may mediate cell communication in the Caenorhabditis elegans sex determination pathway. Mol Biol Cell 1992 1.72
26 The gon-1 gene is required for gonadal morphogenesis in Caenorhabditis elegans. Dev Biol 1999 1.70
27 Mastermind is a putative activator for Notch. Curr Biol 2000 1.69
28 CPEB proteins control two key steps in spermatogenesis in C. elegans. Genes Dev 2000 1.61
29 Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans. Mol Biol Cell 1992 1.55
30 Suppression of an amber mutation by microinjection of suppressor tRNA in C. elegans. Nature 1982 1.55
31 The fog-3 gene and regulation of cell fate in the germ line of Caenorhabditis elegans. Genetics 1995 1.54
32 Control of organ shape by a secreted metalloprotease in the nematode Caenorhabditis elegans. Nature 1999 1.54
33 Regulatory elements required for development of caenorhabditis elegans hermaphrodites are conserved in the tra-2 homologue of C. remanei, a male/female sister species. Genetics 2000 1.49
34 Analysis of the role of tra-1 in germline sex determination in the nematode Caenorhabditis elegans. Genetics 1989 1.46
35 Molecular cloning and transcript analysis of fem-3, a sex-determination gene in Caenorhabditis elegans. Genes Dev 1988 1.41
36 Molecular genetics of sex determination in C. elegans. Trends Genet 1992 1.40
37 Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats. Nature 1993 1.35
38 The mog-1 gene is required for the switch from spermatogenesis to oogenesis in Caenorhabditis elegans. Genetics 1993 1.33
39 The Caenorhabditis elegans sex determining gene fem-3 is regulated post-transcriptionally. EMBO J 1992 1.33
40 Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans. Nature 1991 1.31
41 Molecular analysis of tra-2, a sex determining gene in C.elegans. EMBO J 1991 1.27
42 Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor. EMBO J 1996 1.23
43 Identification of genes that interact with glp-1, a gene required for inductive cell interactions in Caenorhabditis elegans. Development 1989 1.18
44 More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans. Dev Genet 1993 1.18
45 A novel member of the tob family of proteins controls sexual fate in Caenorhabditis elegans germ cells. Dev Biol 2000 1.17
46 Conservation of glp-1 regulation and function in nematodes. Genetics 2001 1.15
47 Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans. Proc Natl Acad Sci U S A 2000 1.15
48 Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans. Mol Biol Cell 1997 1.15
49 The Caenorhabditis elegans sex determination gene mog-1 encodes a member of the DEAH-Box protein family. Mol Cell Biol 1999 1.13
50 A predicted membrane protein, TRA-2A, directs hermaphrodite development in Caenorhabditis elegans. Development 1995 1.13
51 The sys-1 gene and sexual dimorphism during gonadogenesis in Caenorhabditis elegans. Dev Biol 2001 1.10
52 A genetic pathway for regulation of tra-2 translation. Development 1997 1.10
53 Regulation of cell fate in Caenorhabditis elegans by a novel cytoplasmic polyadenylation element binding protein. Dev Biol 2001 1.09
54 Repression by the 3' UTR of fem-3, a sex-determining gene, relies on a ubiquitous mog-dependent control in Caenorhabditis elegans. EMBO J 1998 1.07
55 Confocal methods for Caenorhabditis elegans. Methods Mol Biol 1999 1.05
56 Metal stents improve dysphagia, nutrition and survival in malignant oesophageal stenosis: a randomized controlled trial comparing modified Gianturco Z-stents with plastic Atkinson tubes. Eur J Gastroenterol Hepatol 1998 1.04
57 gon-4, a cell lineage regulator required for gonadogenesis in Caenorhabditis elegans. Dev Biol 2000 1.01
58 Patient-controlled sedation for colonoscopy: a randomized trial comparing patient-controlled administration of propofol and alfentanil with physician-administered midazolam and pethidine. Endoscopy 2003 1.01
59 Germ-line regulation of the Caenorhabditis elegans sex-determining gene tra-2. Dev Biol 1998 1.01
60 A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis. Gene 2000 0.99
61 The hermaphrodite sperm/oocyte switch requires the Caenorhabditis elegans homologs of PRP2 and PRP22. Proc Natl Acad Sci U S A 2000 0.98
62 Control of cell migration during Caenorhabditis elegans development. Curr Opin Cell Biol 1999 0.97
63 APX-1 can substitute for its homolog LAG-2 to direct cell interactions throughout Caenorhabditis elegans development. Proc Natl Acad Sci U S A 1995 0.96
64 The TRA-1 transcription factor binds TRA-2 to regulate sexual fates in Caenorhabditis elegans. EMBO J 2001 0.95
65 Suppressors of glp-1, a gene required for cell communication during development in Caenorhabditis elegans, define a set of interacting genes. Genetics 1993 0.95
66 Genetic control of cell interactions in nematode development. Annu Rev Genet 1991 0.90
67 PUF proteins and 3'UTR regulation in the Caenorhabditis elegans germ line. Cold Spring Harb Symp Quant Biol 2001 0.89
68 glp-3 is required for mitosis and meiosis in the Caenorhabditis elegans germ line. Genetics 1997 0.89
69 Controls of cell fate and pattern by 3' untranslated regions: the Caenorhabditis elegans sperm/oocyte decision. Cold Spring Harb Symp Quant Biol 1997 0.88
70 Patient-controlled sedation and analgesia, using propofol and alfentanil, during colonoscopy: a prospective randomized controlled trial. Endoscopy 1998 0.85
71 C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context. Oncogene 2012 0.83
72 Control of germ cell differentiation in Caenorhabditis elegans. Ciba Found Symp 1994 0.81
73 Genes required for GLP-1 asymmetry in the early Caenorhabditis elegans embryo. Dev Biol 1997 0.80
74 Posttravel hepatitis A: probable acquisition from an asymptomatic adopted child. Clin Infect Dis 2001 0.79
75 Sex Determination in Caenorhabditis elegans. J Nematol 1992 0.78
76 Genetics of intercellular signalling in C. elegans. Development 1989 0.77
77 The 2000 George W. Beadle Medal. John Sulston and Robert Waterston. Genetics 2001 0.75
78 Pattern formation and developmental mechanisms. Curr Opin Genet Dev 1996 0.75
79 The confusion of English consonant clusters in lipreading. J Speech Hear Res 1972 0.75
80 Histochemical investigations on the human fetal subcommissural organ. II. The "large granules". Histochemie 1973 0.75
81 Genetic control of cell communication in C. elegans development. Bioessays 1990 0.75
82 Genetics of development elucidated by nematodes. Nature 1987 0.75