Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
|
EMBO J
|
1998
|
6.08
|
2
|
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
|
Nat Genet
|
2000
|
5.50
|
3
|
p14ARF links the tumour suppressors RB and p53.
|
Nature
|
1998
|
4.78
|
4
|
2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology.
|
J Clin Oncol
|
2001
|
3.25
|
5
|
A population of fast radio bursts at cosmological distances.
|
Science
|
2013
|
3.03
|
6
|
Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product.
|
EMBO J
|
1995
|
2.26
|
7
|
Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.
|
EMBO J
|
1996
|
2.12
|
8
|
Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function.
|
Mol Cell Biol
|
1996
|
1.99
|
9
|
Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia.
|
N Engl J Med
|
1986
|
1.79
|
10
|
Risk of fatal pulmonary embolism in patients with treated venous thromboembolism.
|
JAMA
|
1998
|
1.67
|
11
|
Mdm2 binds p73 alpha without targeting degradation.
|
Oncogene
|
1999
|
1.62
|
12
|
Induction of DNA synthesis and apoptosis are separable functions of E2F-1.
|
Genes Dev
|
1997
|
1.59
|
13
|
Two individuals with elliptocytic red cells apparently lack three minor erythrocyte membrane sialoglycoproteins.
|
Biochem J
|
1984
|
1.56
|
14
|
Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/I(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells.
|
J Clin Endocrinol Metab
|
2001
|
1.54
|
15
|
Intraoperative mannitol does not prevent renal failure in orthotopic liver transplantation.
|
Crit Care Resusc
|
2001
|
1.40
|
16
|
EPOCH chemotherapy: toxicity and efficacy in relapsed and refractory non-Hodgkin's lymphoma.
|
J Clin Oncol
|
1993
|
1.34
|
17
|
E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways.
|
Mol Cell
|
1999
|
1.34
|
18
|
Evidence for different modes of action of cyclin-dependent kinase inhibitors: p15 and p16 bind to kinases, p21 and p27 bind to cyclins.
|
Oncogene
|
1995
|
1.34
|
19
|
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
|
Biochem Biophys Res Commun
|
2001
|
1.33
|
20
|
Generation of a drug resistance profile by quantitation of mdr-1/P-glycoprotein in the cell lines of the National Cancer Institute Anticancer Drug Screen.
|
J Clin Invest
|
1995
|
1.30
|
21
|
Accumulation of p16INK4a in mouse fibroblasts as a function of replicative senescence and not of retinoblastoma gene status.
|
Oncogene
|
1997
|
1.27
|
22
|
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function.
|
Mol Psychiatry
|
2009
|
1.22
|
23
|
Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs.
|
J Clin Invest
|
2000
|
1.22
|
24
|
Paclitaxel in doxorubicin-refractory or mitoxantrone-refractory breast cancer: a phase I/II trial of 96-hour infusion.
|
J Clin Oncol
|
1994
|
1.18
|
25
|
8th San Antonio Breast Cancer Symposium--Plenary lecture. Autocrine and paracrine growth regulation of human breast cancer.
|
Breast Cancer Res Treat
|
1986
|
1.11
|
26
|
Hypercoagulability in patients with primary biliary cirrhosis and primary sclerosing cholangitis evaluated by thrombelastography.
|
J Hepatol
|
1997
|
1.10
|
27
|
Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines.
|
Genes Chromosomes Cancer
|
2000
|
1.09
|
28
|
Morphology of acute promyelocytic leukemia with cytogenetic or molecular evidence for the diagnosis: characterization of additional microgranular variants.
|
Am J Hematol
|
1997
|
1.09
|
29
|
Primary care and population factors associated with NHS Health Check coverage: a national cross-sectional study.
|
J Public Health (Oxf)
|
2013
|
1.08
|
30
|
Autocrine and paracrine growth regulation of human breast cancer.
|
J Steroid Biochem
|
1986
|
1.06
|
31
|
Perturbation of the p53 response by human papillomavirus type 16 E7.
|
J Virol
|
1997
|
1.06
|
32
|
Enhanced adenovirus transgene expression in malignant cells treated with the histone deacetylase inhibitor FR901228.
|
Cancer Res
|
2001
|
1.05
|
33
|
Extracellular protein kinase A as a cancer biomarker: its expression by tumor cells and reversal by a myristate-lacking Calpha and RIIbeta subunit overexpression.
|
Proc Natl Acad Sci U S A
|
2000
|
1.00
|
34
|
A children's acute respiratory illness scale (CARIFS) predicted functional severity and family burden.
|
J Clin Epidemiol
|
2004
|
1.00
|
35
|
Sequence-specific and domain-specific DNA repair in xeroderma pigmentosum and Cockayne syndrome cells.
|
J Biol Chem
|
1997
|
0.99
|
36
|
Optimal insulin delivery in adolescents with diabetes: impact of intensive treatment on psychosocial adjustment.
|
Diabetes Care
|
1984
|
0.98
|
37
|
Does short-term antiepileptic drug treatment in children result in cognitive or behavioral changes?
|
Epilepsia
|
1998
|
0.98
|
38
|
Growth regulation of human breast carcinoma occurs through regulated growth factor secretion.
|
J Cell Biochem
|
1987
|
0.96
|
39
|
Cerebrovascular arteriopathy (arteriosclerosis) and ischemic childhood stroke.
|
Stroke
|
1982
|
0.94
|
40
|
Candida albicans GRX2, encoding a putative glutaredoxin, is required for virulence in a murine model.
|
Genet Mol Res
|
2007
|
0.91
|
41
|
Phase I study of infusional paclitaxel in combination with the P-glycoprotein antagonist PSC 833.
|
J Clin Oncol
|
2001
|
0.91
|
42
|
Effect of an education programme on the utilization of a medical emergency team in a teaching hospital.
|
Intern Med J
|
2006
|
0.89
|
43
|
Candida cell wall mannosylation: importance in host-fungus interaction and potential as a target for the development of antifungal drugs.
|
Biochem Soc Trans
|
1999
|
0.88
|
44
|
Self-rating of pain in nonulcer dyspepsia. A methodological study comparing a new fixed-point scale and the visual analogue scale.
|
J Clin Gastroenterol
|
1987
|
0.88
|
45
|
Functional characterization of the Candida albicans MNT1 mannosyltransferase expressed heterologously in Pichia pastoris.
|
J Biol Chem
|
2000
|
0.88
|
46
|
A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours.
|
Ann Oncol
|
2000
|
0.87
|
47
|
The transcription-repair coupling factor CSA is required for efficient repair only during the elongation stages of RNA polymerase II transcription.
|
Mutat Res
|
1998
|
0.87
|
48
|
Stroke genomics: approaches to identify, validate, and understand ischemic stroke gene expression.
|
J Cereb Blood Flow Metab
|
2001
|
0.87
|
49
|
The efficacy of local anaesthesia for percutaneous epididymal sperm aspiration and testicular sperm aspiration.
|
Hum Reprod
|
1998
|
0.87
|
50
|
Resistance to paclitaxel mediated by P-glycoprotein can be modulated by changes in the schedule of administration.
|
Cancer Chemother Pharmacol
|
1997
|
0.86
|
51
|
Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833.
|
Blood
|
1999
|
0.86
|
52
|
Phase II study of paclitaxel in relapsed non-Hodgkin's lymphomas.
|
J Clin Oncol
|
1995
|
0.85
|
53
|
A high-resolution analysis of chromatin structure along p53 sequences.
|
Mol Carcinog
|
1996
|
0.85
|
54
|
Using the national cancer institute anticancer drug screen to assess the effect of MRP expression on drug sensitivity profiles.
|
Mol Pharmacol
|
1998
|
0.85
|
55
|
Depression in child psychiatric inpatients: cognitive and attributional patterns.
|
J Abnorm Child Psychol
|
1988
|
0.84
|
56
|
Growth regulatory peptide production by human breast carcinoma cells.
|
J Steroid Biochem
|
1988
|
0.83
|
57
|
Radiofrequency thermal ablation of a splenic metastasis.
|
J Vasc Interv Radiol
|
2001
|
0.83
|
58
|
Registration of pain in a psychological perspective.
|
Scand J Gastroenterol Suppl
|
1985
|
0.82
|
59
|
Pediatric victims of unexplained stroke and their families: familial lipid and lipoprotein abnormalities.
|
Pediatrics
|
1982
|
0.82
|
60
|
Recurrent venous thrombosis and heparin therapy: an evaluation of the importance of early activated partial thromboplastin times.
|
Arch Intern Med
|
1999
|
0.81
|
61
|
The multiple faces of the partial thromboplastin time APTT.
|
J Thromb Haemost
|
2004
|
0.80
|
62
|
Childhood-onset depressive disorders. A follow-up study of rates of rehospitalization and out-of-home placement among child psychiatric inpatients.
|
J Affect Disord
|
1989
|
0.80
|
63
|
Low-dose electron beam radiation and romidepsin therapy for symptomatic cutaneous T-cell lymphoma lesions.
|
Br J Dermatol
|
2012
|
0.80
|
64
|
An ATP-binding cassette gene (ABCG3) closely related to the multidrug transporter ABCG2 (MXR/ABCP) has an unusual ATP-binding domain.
|
Mamm Genome
|
2001
|
0.80
|
65
|
Structural and functional changes of rhesus serum low density lipoproteins during cycles of diet-induced hypercholesterolemia.
|
Arteriosclerosis
|
1983
|
0.79
|
66
|
Regulating plant/insect interactions using CO2 enrichment in model ecosystems.
|
Adv Space Res
|
1999
|
0.78
|
67
|
The role of Mucodyne in reducing the need for surgery in patients with persistent otitis media with effusion.
|
Clin Otolaryngol Allied Sci
|
2000
|
0.78
|
68
|
Quantifying amorphous content of lactose using parallel beam X-ray powder diffraction and whole pattern fitting.
|
J Pharm Biomed Anal
|
2001
|
0.78
|
69
|
Variability of the symptoms of chronic abacterial prostatitis/chronic pelvic pain syndrome during intermittent therapy with rectal prednisolone foam for ulcerative colitis.
|
Int J STD AIDS
|
2001
|
0.78
|
70
|
Sphingolipid metabolism. II. The biosynthesis of 3-keto-dihydrosphingosine by a partially-purified enzyme from rat brain.
|
Lipids
|
1970
|
0.77
|
71
|
Estrogens regulate production of specific growth factors in hormone-dependent human breast cancer.
|
Ann N Y Acad Sci
|
1986
|
0.77
|
72
|
An open study of the safety and efficacy of enoxacin in complicated urinary tract infections.
|
J Antimicrob Chemother
|
1988
|
0.77
|
73
|
Effect of an elastin growth substrate on cholesteryl ester synthesis and foam cell formation by cultured aortic smooth muscle cells.
|
Atherosclerosis
|
1987
|
0.76
|
74
|
Audit of cervical cytology in HIV-positive women.
|
Int J STD AIDS
|
2007
|
0.76
|
75
|
Estrogens regulate production of specific growth factors in hormone-dependent human breast cancer.
|
J Lab Clin Med
|
1987
|
0.76
|
76
|
Regulation and function of the cyclin-dependent kinase inhibitor p16CDKN2.
|
Leukemia
|
1997
|
0.76
|
77
|
Dyspepsia. Definition and discussion of nomenclature.
|
Scand J Gastroenterol Suppl
|
1985
|
0.76
|
78
|
Developing an efficient scheduling template of a chemotherapy treatment unit: A case study.
|
Australas Med J
|
2011
|
0.75
|
79
|
Testicular sperm aspiration (TESA): the appropriate technique.
|
Hum Reprod
|
1998
|
0.75
|
80
|
Sclerosing encapsulating peritonitis in rats: an experimental study with intraperitoneal antiseptics.
|
Contrib Nephrol
|
1987
|
0.75
|
81
|
Assisted conception following poor ovarian response to gonadotrophin stimulation.
|
Br J Obstet Gynaecol
|
1997
|
0.75
|
82
|
Reduced schedule of antenatal visits. Attention should be paid to what women want.
|
BMJ
|
1996
|
0.75
|
83
|
Diabetes: controlling the insulin balance. Tight control: what does it mean.
|
Am J Nurs
|
1986
|
0.75
|
84
|
Plasma glucose response to recreational diving in novice teenage divers with insulin-requiring diabetes mellitus.
|
Undersea Hyperb Med
|
2006
|
0.75
|
85
|
Socialization to the culture of a rehabilitation hospital: an ethnographic study.
|
Am J Occup Ther
|
1995
|
0.75
|
86
|
Intra aortic balloon pumping. How to stay on course.
|
Am J Nurs
|
1990
|
0.75
|
87
|
Does intensive glycemic control in diabetic pregnancies result in normalization of other metabolic fuels?
|
Am J Obstet Gynecol
|
1991
|
0.75
|
88
|
Prevalence of paraproteinaemia in older Australians.
|
Intern Med J
|
2012
|
0.75
|
89
|
Myelopathy following intrathecal chemotherapy in a patient with extensive Burkitt's lymphoma and altered immune status.
|
Am J Med
|
1985
|
0.75
|
90
|
Assessing the understanding and prior uptake of human papillomavirus vaccination among eligible females attending genitourinary medicine clinics in UK.
|
Sex Transm Infect
|
2011
|
0.75
|
91
|
Panic anxiety and lactate metabolism.
|
Psychopharmacol Bull
|
1985
|
0.75
|
92
|
Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist.
|
J Clin Pharmacol
|
1997
|
0.75
|
93
|
Risk factor diabetes: long-term follow-up Scheimpflug slit image analysis of lens transparency of diabetic patients.
|
Dev Ophthalmol
|
1991
|
0.75
|
94
|
Try a pre-frontal.
|
Health Serv Manage
|
1989
|
0.75
|
95
|
Behavioral descriptors that differentiate between seizure and nonseizure events in a pediatric population.
|
Clin Pediatr (Phila)
|
1996
|
0.75
|
96
|
Data watch. Networking most extensive among largest hospitals.
|
Hosp Health Netw
|
1994
|
0.75
|
97
|
Discrepancies between blood glucose and glycosylated hemoglobin in intensively treated diabetic patients.
|
Diabetes Educ
|
1988
|
0.75
|
98
|
Psychological group counseling for the prevention of ulcer relapses. A controlled randomized trial in duodenal and prepyloric ulcer disease.
|
J Clin Gastroenterol
|
1987
|
0.75
|
99
|
Effects of PALA on the pharmacokinetics of 5-fluorouracil.
|
Oncol Rep
|
1998
|
0.75
|
100
|
Hypoglycaemic activity of an HMG-containing flavonoid glucoside, chamaemeloside, from Chamaemelum nobile.
|
Planta Med
|
1998
|
0.75
|
101
|
Blood loss following tonsillectomy in children. A blind comparison of diclofenac and papaveretum.
|
Anaesthesia
|
1993
|
0.75
|