Low-complexity regions in Plasmodium falciparum proteins.

PubWeight™: 2.14‹?› | Rank: Top 2%

🔗 View Article (PMC 311019)

Published in Genome Res on February 01, 2001

Authors

E Pizzi1, C Frontali

Author Affiliations

1: Laboratorio di Biologia Cellulare, Istituto Superiore di Sanitá, 00161 Rome, Italy.

Articles citing this

A sporozoite asparagine-rich protein controls initiation of Plasmodium liver stage development. PLoS Pathog (2008) 1.65

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol (2008) 1.56

Prediction of the general transcription factors associated with RNA polymerase II in Plasmodium falciparum: conserved features and differences relative to other eukaryotes. BMC Genomics (2005) 1.53

Detection of genome-wide polymorphisms in the AT-rich Plasmodium falciparum genome using a high-density microarray. BMC Genomics (2008) 1.38

Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome. Mol Biol Evol (2010) 1.23

Molecular cloning of apicoplast-targeted Plasmodium falciparum DNA gyrase genes: unique intrinsic ATPase activity and ATP-independent dimerization of PfGyrB subunit. Eukaryot Cell (2007) 1.08

Optimum growth temperature and the base composition of open reading frames in prokaryotes. Extremophiles (2003) 1.07

RepSeq--a database of amino acid repeats present in lower eukaryotic pathogens. BMC Bioinformatics (2007) 1.06

Evolutionary sequence analysis of complete eukaryote genomes. BMC Bioinformatics (2005) 0.97

Protein arginine methylation in parasitic protozoa. Eukaryot Cell (2011) 0.97

Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains. BMC Genomics (2013) 0.95

PlasmoDraft: a database of Plasmodium falciparum gene function predictions based on postgenomic data. BMC Bioinformatics (2008) 0.93

Crystal structure of arginase from Plasmodium falciparum and implications for L-arginine depletion in malarial infection . Biochemistry (2010) 0.92

A comparative proteomic analysis of the simple amino acid repeat distributions in Plasmodia reveals lineage specific amino acid selection. PLoS One (2009) 0.92

A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins. BMC Bioinformatics (2008) 0.89

Parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine decarboxylase of Plasmodium falciparum modulate catalytic activities and domain interactions. Biochem J (2004) 0.88

Variable numbers of tandem repeats in Plasmodium falciparum genes. J Mol Evol (2010) 0.87

An evolutionary perspective on the kinome of malaria parasites. Philos Trans R Soc Lond B Biol Sci (2012) 0.85

Plasmodial aspartyl-tRNA synthetases and peculiarities in Plasmodium falciparum. J Biol Chem (2009) 0.84

Protein-based signatures of functional evolution in Plasmodium falciparum. BMC Evol Biol (2011) 0.84

Deletion mutagenesis of large areas in Plasmodium falciparum genes: a comparative study. Malar J (2007) 0.84

Proteome composition in Plasmodium falciparum: higher usage of GC-rich nonsynonymous codons in highly expressed genes. J Mol Evol (2005) 0.83

Low-complexity regions in Plasmodium proteins: in search of a function. Genome Res (2001) 0.83

Assessing functional annotation transfers with inter-species conserved coexpression: application to Plasmodium falciparum. BMC Genomics (2010) 0.82

LCR-eXXXplorer: a web platform to search, visualize and share data for low complexity regions in protein sequences. Bioinformatics (2015) 0.80

Simple sequence proteins in prokaryotic proteomes. BMC Genomics (2006) 0.80

Comparative genome analysis of six malarial parasites using codon usage bias based tools. Bioinformation (2012) 0.79

Genetic polymorphism of Plasmodium vivax msp1p, a paralog of merozoite surface protein 1, from worldwide isolates. Am J Trop Med Hyg (2011) 0.78

Identification and bioinformatics characterization of translation initiation complex eIF4F components and poly(A)-binding protein from Plasmodium falciparum. Commun Integr Biol (2009) 0.78

Specific tagging of the egress-related osmiophilic bodies in the gametocytes of Plasmodium falciparum. Malar J (2012) 0.78

A fine functional homology between chitinases from host and parasite is relevant for malaria transmissibility. Parasitol Res (2007) 0.77

Aminoacylation of Plasmodium falciparum tRNA(Asn) and insights in the synthesis of asparagine repeats. J Biol Chem (2013) 0.77

Fitting hidden Markov models of protein domains to a target species: application to Plasmodium falciparum. BMC Bioinformatics (2012) 0.77

Homopolymer tract organization in the human malarial parasite Plasmodium falciparum and related Apicomplexan parasites. BMC Genomics (2014) 0.77

Profiles of low complexity regions in Apicomplexa. BMC Evol Biol (2016) 0.76

Extreme mutation bias and high AT content in Plasmodium falciparum. Nucleic Acids Res (2017) 0.75

K-mer Content, Correlation, and Position Analysis of Genome DNA Sequences for the Identification of Function and Evolutionary Features. Genes (Basel) (2017) 0.75

Preferential binding of 4-hydroxynonenal to lysine residues in specific parasite proteins in plakortin-treated Plasmodium falciparum-parasitized red blood cells. Data Brief (2015) 0.75

Articles cited by this

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47

A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res (1984) 181.98

A simple method for displaying the hydropathic character of a protein. J Mol Biol (1982) 150.65

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm. J Mol Biol (1999) 11.38

Molecular drive: a cohesive mode of species evolution. Nature (1982) 8.79

Sequence complexity of disordered protein. Proteins (2001) 6.97

Cryptic simplicity in DNA is a major source of genetic variation. Nature (1986) 4.68

Non-globular domains in protein sequences: automated segmentation using complexity measures. Comput Chem (1994) 4.36

Repetitive proteins and genes of malaria. Annu Rev Microbiol (1987) 4.30

Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science (1998) 3.83

Methods and algorithms for statistical analysis of protein sequences. Proc Natl Acad Sci U S A (1992) 3.63

The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Nature (1999) 3.44

Dynamical assessment of physiological systems and states using recurrence plot strategies. J Appl Physiol (1985) (1994) 3.31

Accuracy of protein flexibility predictions. Proteins (1994) 2.14

Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development. Proc Natl Acad Sci U S A (1996) 1.99

Complete DNA sequence of yeast chromosome II. EMBO J (1994) 1.97

Hydrophobicity regained. Protein Sci (1997) 1.80

Thousands of proteins likely to have long disordered regions. Pac Symp Biocomput (1998) 1.79

A global compositional complexity measure for biological sequences: AT-rich and GC-rich genomes encode less complex proteins. Comput Chem (2000) 1.63

Analysis of sequences from the extremely A + T-rich genome of Plasmodium falciparum. Gene (1987) 1.52

Amino acid reiterations in yeast are overrepresented in particular classes of proteins and show evidence of a slippage-like mutational process. J Mol Evol (1999) 1.32

Codon reiteration and the evolution of proteins. Proc Natl Acad Sci U S A (1994) 1.29

The correlation of protein hydropathy with the base composition of coding sequences. Gene (1999) 1.22

Does biased gene conversion influence polymorphism in the circumsporozoite protein-encoding gene of Plasmodium vivax? Proc Natl Acad Sci U S A (1988) 1.19

Deviations from Chargaff's second parity rule correlate with direction of transcription. J Theor Biol (1999) 1.11

Antigenic variation and immune evasion in Plasmodium falciparum malaria. Immunol Cell Biol (1996) 1.07

Flexibility plot of proteins. Protein Eng (1989) 1.02

Biased amino acid composition in repeat regions of Plasmodium antigens. Mol Biol Evol (1999) 1.01

The putative gamma-glutamylcysteine synthetase from Plasmodium falciparum contains large insertions and a variable tandem repeat. Mol Biochem Parasitol (1999) 1.00

Evolutionary profile of the circumsporozoite gene of the Plasmodium cynomolgi complex. J Mol Biol (1986) 0.99

Simple sequence is abundant in eukaryotic proteins. Protein Sci (1999) 0.98

SEGMENT: identifying compositional domains in DNA sequences. Bioinformatics (1999) 0.95

Zones of low entropy in genomic sequences. Comput Chem (1999) 0.93

Detection of latent sequence periodicities. Nucleic Acids Res (1990) 0.87

Divergence of noncoding sequences and of insertions encoding nonglobular domains at a genomic region well conserved in plasmodia. J Mol Evol (2000) 0.87

Genome plasticity in Plasmodium. Genetica (1994) 0.86

An analysis of structural instances of low complexity sequence segments. Protein Eng (1995) 0.86

Conservation and divergence of repeated structures in Plasmodium genomes: the molecular drift. Acta Leiden (1991) 0.85

Similarity in oligonucleotide usage in introns and intergenic regions contributes to long-range correlation in the Caenorhabditis elegans genome. Gene (1999) 0.84

The putative gene for the first enzyme of glutathione biosynthesis in Plasmodium berghei and Plasmodium falciparum. Mol Biochem Parasitol (1999) 0.84

Local-scale repetitiveness in amino acid use in eukaryote protein sequences: a genomic factor in protein evolution. Proteins (1999) 0.83

Compositional constraints in the extremely GC-poor genome of Plasmodium falciparum. Mem Inst Oswaldo Cruz (1998) 0.82

Articles by these authors

Identification of a telomeric DNA sequence in Plasmodium berghei. EMBO J (1985) 1.78

Structure and physico-chemical properties of bacteriophage G. III. A homogeneous DNA of molecular weight 5 times 10(8). J Mol Biol (1975) 1.67

An absolute method for the determination of the persistence length of native DNA from electron micrographs. Biopolymers (1979) 1.64

Telomeric motifs are present in a highly repetitive element in the Plasmodium berghei genome. Mol Biochem Parasitol (1987) 1.36

The alkaline denaturation of DNA. Biophys J (1969) 1.12

Organization of subtelomeric repeats in Plasmodium berghei. Mol Cell Biol (1990) 1.09

Physico-chemical description of a condensed form of DNA. Biopolymers (1972) 1.05

The molecular complexity of G DNA. Virology (1977) 1.04

Viscosity measurements of alcohol-water mixtures and the structure of water. Proc Natl Acad Sci U S A (1967) 1.00

Homologous telomeric sequences are present in different species of the genus Plasmodium. Mol Biochem Parasitol (1986) 0.98

Interaction between denatured DNA and RNA from Bacillus stearothermophilus involving only one-half of total DNA. J Mol Biol (1966) 0.96

Extensive turnover of telomeric DNA at a Plasmodium berghei chromosomal extremity marked by a rare recombinational event. Nucleic Acids Res (1992) 0.90

Long insertions within telomeres contribute to chromosome size polymorphism in Plasmodium berghei. Mol Cell Biol (1990) 0.88

Further studies and electron microscopic characterization of Plasmodium berghei DNA. Mol Biochem Parasitol (1983) 0.87

Detection of latent sequence periodicities. Nucleic Acids Res (1990) 0.87

Divergence of noncoding sequences and of insertions encoding nonglobular domains at a genomic region well conserved in plasmodia. J Mol Evol (2000) 0.87

Mosquito infectivity is directly related to the proportion of repetitive DNA in Plasmodium berghei. Mol Biochem Parasitol (1982) 0.85

A site of intrinsic bending in a highly repeated element of Plasmodium berghei genome. Mol Biochem Parasitol (1988) 0.84

Excluded-volume effect on the bidimensional conformation of DNA molecules adsorbed to protein films. Biopolymers (1988) 0.84

Dynamics of telomere turnover in Plasmodium berghei. Mol Biol Rep (1994) 0.83

Molecular evolution of coding and non-coding regions in Plasmodium. Parassitologia (1999) 0.82

Structure and superstructure of Plasmodium falciparum subtelomeric regions. Mol Biochem Parasitol (1995) 0.81

Fine structure of Plasmodium falciparum subtelomeric sequences. Mol Biochem Parasitol (2001) 0.80

Re-examination of earlier work on repetitive DNA and mosquito infectivity in rodent malaria. Mol Biochem Parasitol (1985) 0.79

A simple method for global sequence comparison. Nucleic Acids Res (1992) 0.75

On the nature of the pseudohybrids between denatured DNA and ribosomal RNA. Ann Ist Super Sanita (1966) 0.75

[Growth curves of Bacillus megaterium on solid media]. Ann Ist Super Sanita (1966) 0.75

Unspoken fears. Nature (1991) 0.75

Mobile repeat units in Plasmodium berghei. Parassitologia (1993) 0.75

[Significance and limitations of taxonomic tests]. Ann Ist Super Sanita (1979) 0.75

Safe biotechnology (4). Recommendations for safety levels for biotechnological operations with microorganisms that cause diseases in plants. Appl Microbiol Biotechnol (1992) 0.75

[Description of a temperate phage of Bacillus megatherium]. Ann Ist Super Sanita (1965) 0.75

The role of ions in the acid melting of DNA. Biopolymers (1972) 0.75

[Calibration of gel-chromatographic columns for examination of dextrans for clinical use]. Ann Ist Super Sanita (1976) 0.75

Subtelomeric structure of Plasmodium falciparum chromosomes. Mem Inst Oswaldo Cruz (1994) 0.75

Letter: Electron microscopic observation of DNA condensates at low pH values. J Mol Biol (1973) 0.75

Safe biotechnology (5). Recommendations for safe work with animal and human cell cultures concerning potential human pathogens. Appl Microbiol Biotechnol (1993) 0.75

[Still open problems on the structure of the deoxyribonucleic acid molecule]. Ann Ist Super Sanita (1966) 0.75

[Isoenzyme typing of strains of Plasmodium berghei and Plasmodium yoelii]. Ann Ist Super Sanita (1986) 0.75

Problems in basic biology of Plasmodia. Ann Ist Super Sanita (1985) 0.75

Cytofluorimetric analysis of DNA content in different life stages of Plasmodium yoelii. Ann Ist Super Sanita (1985) 0.75