Aldehyde dehydrogenase. Maintaining critical active site geometry at motif 8 in the class 3 enzyme.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMID 11168411)

Published in Eur J Biochem on February 01, 2001

Authors

J Hempel1, I Kuo, J Perozich, B C Wang, R Lindahl, H Nicholas

Author Affiliations

1: Department of Biological Sciences, University of Pittsburgh, Pittsburgh 15620, USA. hempel@psc.edu

Articles citing this

Non-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamily. Expert Opin Drug Metab Toxicol (2008) 3.37

Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity. J Mol Biol (2006) 1.10

Expression and initial characterization of human ALDH3B1. Biochem Biophys Res Commun (2007) 0.90

Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress. Free Radic Biol Med (2010) 0.87

A gatekeeper helix determines the substrate specificity of Sjögren-Larsson Syndrome enzyme fatty aldehyde dehydrogenase. Nat Commun (2014) 0.82

Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases. Protein Sci (2006) 0.82

Novel and recurrent ALDH3A2 mutations in Italian patients with Sjögren-Larsson syndrome. J Hum Genet (2007) 0.81

Automatic discovery of cross-family sequence features associated with protein function. BMC Bioinformatics (2006) 0.79

The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1. Chem Biol Interact (2013) 0.78

Trade-off between toxicity and signal detection orchestrated by frequency- and density-dependent genes. PLoS One (2011) 0.77

Activation of Human Salivary Aldehyde Dehydrogenase by Sulforaphane: Mechanism and Significance. PLoS One (2016) 0.75

Identification and characterization of a mandelamide hydrolase and an NAD(P)+-dependent benzaldehyde dehydrogenase from Pseudomonas putida ATCC 12633. J Bacteriol (2003) 0.75

Biophysical studies of an NAD(P)(+)-dependent aldehyde dehydrogenase from Bacillus licheniformis. Eur Biophys J (2011) 0.75

Articles by these authors

Resolution of phase ambiguity in macromolecular crystallography. Methods Enzymol (1985) 11.92

Structure of the DNA-Eco RI endonuclease recognition complex at 3 A resolution. Science (1986) 4.89

The nucleosomal core histone octamer at 3.1 A resolution: a tripartite protein assembly and a left-handed superhelix. Proc Natl Acad Sci U S A (1991) 4.76

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution. Nature (1993) 3.69

Kinked DNA in crystalline complex with EcoRI endonuclease. Nature (1984) 2.46

The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold. Nat Struct Biol (1997) 2.34

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase. Proc Natl Acad Sci U S A (1991) 2.34

The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis. Nat Struct Biol (2001) 1.96

Structure of a novel Bence-Jones protein (Rhe) fragment at 1.6 A resolution. J Mol Biol (1983) 1.88

Relationships within the aldehyde dehydrogenase extended family. Protein Sci (1999) 1.79

Aldehyde dehydrogenases: widespread structural and functional diversity within a shared framework. Protein Sci (1993) 1.76

Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease. J Neurol (1993) 1.71

Refined crystal structure of Cd, Zn metallothionein at 2.0 A resolution. J Mol Biol (1991) 1.70

Molecular structure of troponin C from chicken skeletal muscle at 3-angstrom resolution. Science (1985) 1.66

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in health care workers (HCWs): guidelines for prevention of transmission of HBV and HCV from HCW to patients. J Clin Virol (2003) 1.53

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs. Am J Physiol (1988) 1.50

Crystallographic structure of the octameric histone core of the nucleosome at a resolution of 3.3 A. Science (1985) 1.49

The structure of glutamine-binding protein complexed with glutamine at 1.94 A resolution: comparisons with other amino acid binding proteins. J Mol Biol (1998) 1.48

The crystal structure of glutamine-binding protein from Escherichia coli. J Mol Biol (1996) 1.42

Strand breaks, base release, and postirradiation changes in DNA gamma-irradiated in dilute O2-saturated aqueous solution. Radiat Res (1976) 1.41

Ferrochelatase at the millennium: structures, mechanisms and [2Fe-2S] clusters. Cell Mol Life Sci (2000) 1.38

Crystal structure of the transcription factor sc-mtTFB offers insights into mitochondrial transcription. Protein Sci (2001) 1.33

Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors. J Biol Chem (1992) 1.33

The Prevalence of Undiagnosed HIV Infection in Those Who Decline HIV Screening in an Urban Emergency Department. AIDS Res Treat (2011) 1.32

Structure of the Ca2+-regulated photoprotein obelin at 1.7 A resolution determined directly from its sulfur substructure. Protein Sci (2000) 1.29

Family planning in genitourinary medicine: an opportunistic service? Genitourin Med (1995) 1.25

Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atom. Proc Natl Acad Sci U S A (1991) 1.24

High field-effect mobility oligofluorene derivatives with high environmental stability. J Am Chem Soc (2001) 1.16

Crystal structure of Cd,Zn metallothionein. Science (1986) 1.15

Discovery of the ammonium substrate site on glutamine synthetase, a third cation binding site. Protein Sci (1995) 1.14

Amino acid microsequencing of internal tryptic peptides of heme-regulated eukaryotic initiation factor 2 alpha subunit kinase: homology to protein kinases. Proc Natl Acad Sci U S A (1991) 1.12

Cloning and complete nucleotide sequence of a full-length cDNA encoding a catalytically functional tumor-associated aldehyde dehydrogenase. Proc Natl Acad Sci U S A (1988) 1.09

Phenobarbital-inducible aldehyde dehydrogenase in the rat. cDNA sequence and regulation of the mRNA by phenobarbital in responsive rats. J Biol Chem (1989) 1.07

The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration. J Neurol Neurosurg Psychiatry (2006) 1.03

Localization of the human lactate dehydrogenase B gene on the short arm of chromosome 12. Am J Hum Genet (1974) 1.03

Occupational exposure to chain saw exhausts in logging operations. Am Ind Hyg Assoc J (1987) 1.02

Irritative complaints, carboxyhemoglobin increase and minor ventilatory function changes due to exposure to chain-saw exhaust. Eur J Respir Dis (1985) 1.01

UDP-glucose dehydrogenase from bovine liver: primary structure and relationship to other dehydrogenases. Protein Sci (1994) 1.00

Role of aldehyde metabolizing enzymes in mediating effects of aldehyde products of lipid peroxidation in liver cells. Carcinogenesis (1994) 1.00

Atrial stretch increases sodium excretion independently of release of atrial peptides. Am J Physiol (1986) 0.95

Comparison of the chemical, physical, and survival properties of normal and Z-variant alpha-1-antitrypsins. J Biol Chem (1976) 0.95

Shifting the NAD/NADP preference in class 3 aldehyde dehydrogenase. Eur J Biochem (2000) 0.94

Immunoassay of serum polypeptide hormones by using 125I-labelled anti(-immunoglobulin G) antibodies. Biochem J (1975) 0.94

Aldehyde dehydrogenase catalytic mechanism. A proposal. Adv Exp Med Biol (1999) 0.94

Crystal structure of the neurophysin-oxytocin complex. Nat Struct Biol (1996) 0.94

Crystal structure of Azotobacter cytochrome c5 at 2.5 A resolution. J Mol Biol (1985) 0.93

UDP-glucose dehydrogenase: substrate binding stoichiometry and affinity. Biochem Biophys Res Commun (1973) 0.93

Efficiency of automotive cabin air filters to reduce acute health effects of diesel exhaust in human subjects. Occup Environ Med (1999) 0.93

Radiation damage to DNA in aqueous solution: a comparison of the response of the single-stranded form with that of the double-stranded form. Radiat Res (1978) 0.93

Inducible (class 3) aldehyde dehydrogenase from rat hepatocellular carcinoma and 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated liver: distant relationship to the class 1 and 2 enzymes from mammalian liver cytosol/mitochondria. Biochemistry (1989) 0.93

Sequence and genomic structure of the human adult skeletal muscle sodium channel alpha subunit gene on 17q. Biochem Biophys Res Commun (1992) 0.92

Purification and immunochemical characterization of aldehyde dehydrogenase from 2-acetylaminofluorene-induced rat hepatomas. Biochim Biophys Acta (1976) 0.92

The crystal structures of Phascolopsis gouldii wild type and L98Y methemerythrins: structural and functional alterations of the O2 binding pocket. J Biol Inorg Chem (2001) 0.91

Rat liver aldehyde dehydrogenase. II. Isolation and characterization of four inducible isozymes. J Biol Chem (1984) 0.91

Novel arrangement of immunoglobulin variable domains: X-ray crystallographic analysis of the lambda-chain dimer Bence-Jones protein Loc. Biochemistry (1985) 0.90

The thumb's knuckle. Flexibility in the thumb subdomain of T7 RNA polymerase is revealed by the structure of a chimeric T7/T3 RNA polymerase. J Mol Biol (1994) 0.90

The big book of aldehyde dehydrogenase sequences. An overview of the extended family. Adv Exp Med Biol (1999) 0.90

Hydride transfer stereospecificity of rat liver aldehyde dehydrogenases. J Biol Chem (1987) 0.89

Plasma spraying of zirconia-reinforced hydroxyapatite composite coatings on titanium: part I: phase, microstructure and bonding strength. J Mater Sci Mater Med (1997) 0.88

Coenzyme specificity in aldehyde dehydrogenase. Chem Biol Interact (2001) 0.87

Crystal structure of Bence Jones protein rhe (3 A) and its unique domain-domain association. J Mol Biol (1979) 0.87

Detection of oxidases on polyacrylamide gels. Anal Biochem (1973) 0.86

Characterization of rat cornea aldehyde dehydrogenase. Arch Biochem Biophys (1989) 0.86

Vasopressin in plasma and cerebrospinal fluid of dogs during hypoxia or acidosis. Am J Physiol (1984) 0.85

Analysis of some older Scandinavian formulations of 2,4-dichlorophenoxy acetic acid and 2,4,5-trichlorophenoxy acetic acid for contents of chlorinated dibenzo-p-dioxins and dibenzofurans. Scand J Work Environ Health (1979) 0.85

Acute effects of cigarette smoking on pulmonary function. Am Rev Respir Dis (1970) 0.85

Oxazaphosphorine-specific resistance in human MCF-7 breast carcinoma cell lines expressing transfected rat class 3 aldehyde dehydrogenase. J Biol Chem (1994) 0.85

Crystals of glutamine-binding protein in various conformational states. J Mol Biol (1994) 0.85

Inhibition of class-3 aldehyde dehydrogenase and cell growth by restored lipid peroxidation in hepatoma cell lines. Free Radic Biol Med (1999) 0.84

Thiol proteases and aldehyde dehydrogenases: evolution from a common thiolesterase precursor? Proteins (1991) 0.84

Rat liver aldehyde dehydrogenase. I. Isolation and characterization of four high Km normal liver isozymes. J Biol Chem (1984) 0.84

Structural basis for the substrate specificity of the feruloyl esterase domain of the cellulosomal xylanase Z from Clostridium thermocellum. Biochemistry (2001) 0.84

Characterization of aldehyde dehydrogenase from HTC rat hepatoma cells. Biochim Biophys Acta (1985) 0.84

Sexual Behaviors of US Women at Risk of HIV Acquisition: A Longitudinal Analysis of Findings from HPTN 064. AIDS Behav (2015) 0.84

Beyond the catalytic core of ALDH: a web of important residues begins to emerge. Chem Biol Interact (2001) 0.84

Class III aldehyde dehydrogenase from rat liver: super-family relationship to classes I and II and functional interpretations. Prog Clin Biol Res (1989) 0.83

Organization and characterization of the rat class 3 aldehyde dehydrogenase gene. J Biol Chem (1993) 0.83

Comparative subcellular distribution of aldehyde dehydrogenase in rat, mouse and rabbit liver. Biochem Pharmacol (1984) 0.83

Expression of tumor-associated aldehyde dehydrogenase during rat hepatocarcinogenesis using the resistant hepatocyte model. Carcinogenesis (1984) 0.83

Midlife Neuroticism and the age of onset of Alzheimer's disease. Psychol Med (2008) 0.83

Crystallization and preliminary crystallographic data for the augmenter of liver regeneration. Acta Crystallogr D Biol Crystallogr (1997) 0.83

In vitro and in vivo mechanical evaluations of plasma-sprayed hydroxyapatite coatings on titanium implants: the effect of coating characteristics. J Biomed Mater Res (1997) 0.83

Single crystals of bacteriophage T7 RNA polymerase. Proteins (1989) 0.82

Types of female partners reported by black men who have sex with men and women (MSMW) and associations with intercourse frequency, unprotected sex and HIV and STI prevalence. AIDS Behav (2014) 0.82