PubRank

M Jäättelä

Author PubWeight™ 57.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Four deaths and a funeral: from caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001 4.61
2 Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 2007 3.50
3 Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ 2009 3.44
4 Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res 2001 3.38
5 Heat-shock protein 70 antagonizes apoptosis-inducing factor. Nat Cell Biol 2001 3.05
6 Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor. J Cell Biol 2001 2.68
7 Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death. Cell Death Differ 2005 2.29
8 Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2. Proc Natl Acad Sci U S A 2000 2.10
9 Heat shock protein 70 overexpression affects the response to ultraviolet light in murine fibroblasts. Evidence for increased cell viability and suppression of cytokine release. J Clin Invest 1995 1.49
10 Heat shock protein 70 is required for the survival of cancer cells. Ann N Y Acad Sci 2000 1.44
11 Triggering of apoptosis by cathepsins. Cell Death Differ 2001 1.39
12 Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proc Natl Acad Sci U S A 1997 1.32
13 Apoptosis induced by vitamin D compounds in breast cancer cells is inhibited by Bcl-2 but does not involve known caspases or p53. Cancer Res 1999 1.32
14 Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells. Cell Death Differ 2005 1.28
15 Heat shock protein hsp70 overexpression confers resistance against nitric oxide. FEBS Lett 1996 1.21
16 The ability of BHRF1 to inhibit apoptosis is dependent on stimulus and cell type. J Virol 1997 1.19
17 Production of tumour necrosis factor and interleukin 1 by monocytes of patients with previous Yersinia arthritis. Clin Exp Immunol 1988 1.16
18 Cancer-associated lysosomal changes: friends or foes? Oncogene 2012 1.10
19 JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways. Cell Death Differ 2004 1.06
20 Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation. EMBO J 1997 1.05
21 Selective depletion of inducible HSP70 enhances immunogenicity of rat colon cancer cells. Oncogene 2001 1.00
22 BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells. Biochem Biophys Res Commun 2001 0.98
23 HSP70 overexpression mediates the escape of a doxorubicin-induced G2 cell cycle arrest. Biochem Biophys Res Commun 1996 0.96
24 A20 zinc finger protein inhibits TNF-induced apoptosis and stress response early in the signaling cascades and independently of binding to TRAF2 or 14-3-3 proteins. Cell Death Differ 2001 0.95
25 Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family. Breast Cancer Res Treat 1999 0.95
26 Identification of a c-Jun N-terminal kinase-2-dependent signal amplification cascade that regulates c-Myc levels in ras transformation. Oncogene 2011 0.93
27 Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells. Int J Cancer 2000 0.93
28 Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology. Int J Cancer 2001 0.91
29 In vivo and in vitro evidence for extracellular caspase activity released from apoptotic cells. Biochem Biophys Res Commun 2001 0.90
30 Sensitization to TNF-induced apoptosis by 1,25-dihydroxy vitamin D(3) involves up-regulation of the TNF receptor 1 and cathepsin B. Int J Cancer 2001 0.90
31 Hsp70-RAP46 interaction in downregulation of DNA binding by glucocorticoid receptor. EMBO J 2000 0.88
32 Depletion of the AP-1 repressor JDP2 induces cell death similar to apoptosis. Biochim Biophys Acta 2005 0.84
33 Production of TNF by monocytes of patients with early rheumatoid arthritis is increased. Scand J Rheumatol 1995 0.83
34 TNF-induced mitochondrial changes and activation of apoptotic proteases are inhibited by A20. Free Radic Biol Med 1998 0.83
35 Phagocyte function in familial hypercholesterolaemia: peripheral blood monocytes exposed to lipopolysaccharide show increased tumour necrosis factor production. Scand J Immunol 1990 0.83
36 HSP27 and HSP70 increase the survival of WEHI-S cells exposed to hyperthermia. Int J Hyperthermia 1996 0.82
37 Phagocyte function in juvenile periodontitis. Infect Immun 1990 0.80
38 Peripheral blood monocytes from patients with reactive arthritis show normal production of tumour necrosis factor-alpha. Clin Exp Immunol 1991 0.80
39 Tumor necrosis factor in the human fetoplacentary unit. Int J Dev Biol 1989 0.79
40 A sub-set of immediate early mRNAs induced by tumor necrosis factor-alpha during cellular cytotoxic and non-cytotoxic responses. Int J Cancer 1993 0.78
41 Heat shock protein 70 inhibits shrinkage-induced programmed cell death via mechanisms independent of effects on cell volume-regulatory membrane transport proteins. Pflugers Arch 2004 0.78
42 Tumor necrosis factor-alpha and interferon-gamma inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures. Mol Cell Endocrinol 1993 0.75