Published in J Clin Invest on April 01, 1975
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci U S A (1990) 5.31
Elevated inflammatory markers in response to prolonged sleep restriction are associated with increased pain experience in healthy volunteers. Sleep (2007) 2.55
Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. J Clin Invest (1982) 2.23
A new recommended dietary allowance of vitamin C for healthy young women. Proc Natl Acad Sci U S A (2001) 2.12
Drug off-target effects predicted using structural analysis in the context of a metabolic network model. PLoS Comput Biol (2010) 1.97
Ionophores stimulate prostaglandin and thromboxane biosynthesis. Proc Natl Acad Sci U S A (1977) 1.82
Evidence for a direct stimulatory effect of prostacyclin on renin release in man. J Clin Invest (1982) 1.57
Prostaglandin biosynthesis by rabbit renomedullary interstitial cells in tissue culture. Stimulation by angiotensin II, bradykinin, and arginine vasopressin. J Clin Invest (1977) 1.50
Changes in renal medullary pO2 during water diuresis as evaluated by blood oxygenation level-dependent magnetic resonance imaging: effects of aging and cyclooxygenase inhibition. Kidney Int (1999) 1.44
Exaggerated prostaglandin biosynthesis and its influence on renal resistance in the isolated hydronephrotic rabbit kidney. J Clin Invest (1977) 1.42
Urinary prostaglandin E2 metabolite and gastric cancer risk in the Shanghai women's health study. Cancer Epidemiol Biomarkers Prev (2009) 1.23
Contribution of prostaglandins to the systemic and renal vascular response to frusemide in normal man. Br J Clin Pharmacol (1984) 1.17
Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy. Serial studies in chronically instrumented, conscious rats. J Clin Invest (1986) 1.13
Increased glomerular thromboxane synthesis as a possible cause of proteinuria in experimental nephrosis. J Clin Invest (1985) 1.08
Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus. J Clin Invest (1985) 1.06
Prostaglandin synthesis in isolated rat kidney glomeruli. Proc Natl Acad Sci U S A (1979) 1.06
A comparison of the effects of ibuprofen and indomethacin upon renal haemodynamics and electrolyte excretion in the presence and absence of frusemide. Br J Clin Pharmacol (1989) 0.97
Effect of captopril on uterine blood flow and prostaglandin E synthesis in the pregnant rabbit. J Clin Invest (1983) 0.96
Possible influence of intrarenal generation of kinins on prostaglandin release from the rabbit perfused kidney. Br J Pharmacol (1976) 0.96
Effect of vasopressin on prostaglandin excretion in conscious dogs. J Physiol (1983) 0.96
Effects of acetylsalicylic acid and paracetamol alone and in combination on prostanoid synthesis in man. Br J Clin Pharmacol (1990) 0.92
The effects of sulindac and indomethacin on the anti-hypertensive and diuretic action of hydrochlorothiazide in patients with mild to moderate essential hypertension. Br J Clin Pharmacol (1986) 0.91
Angiotensin II-induced hypertension in the rat. Effects on the plasma concentration, renal excretion, and tissue release of prostaglandins. J Clin Invest (1983) 0.88
Prostaglandin synthesis and renal function in man. J Physiol (1980) 0.88
Urinary PGE-M levels are associated with risk of colorectal adenomas and chemopreventive response to anti-inflammatory drugs. Cancer Prev Res (Phila) (2014) 0.88
Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man. Br J Clin Pharmacol (1986) 0.88
Increased urinary kallikrein excretion during prostaglandin E1 infusion in anaesthetized dogs and its relation to natriuresis and diuresis. J Physiol (1977) 0.88
Prostaglandin E production and hypercalcaemia in rats bearing the Walker carcinosarcoma. Br J Cancer (1980) 0.87
The effect of altered sodium balance upon renal vascular reactivity to angiotensin II and norepinephrine in the dog. Mechanism of variation in angiotensin responses. J Clin Invest (1978) 0.86
Prostaglandin E2 excretion, urine flow and papillary osmolality during saline or dextrose infusion in the conscious rat. J Physiol (1983) 0.84
Gut-mediated hypercalcemia in rabbits bearing VX2 carcinoma: new mechanism for tumor-induced hypercalcemia. Proc Natl Acad Sci U S A (1982) 0.83
Lipid peroxidation products as potential bioindicators of Lyme arthritis. Eur J Clin Microbiol Infect Dis (2010) 0.81
Autistic children exhibit decreased levels of essential Fatty acids in red blood cells. Int J Mol Sci (2015) 0.81
Frusemide, ACE inhibition, renal dopamine and prostaglandins: acute interactions in normal man. Br J Clin Pharmacol (1989) 0.80
Effect of urinary pH and urine flow rate on prostaglandin E2 and kallikrein excretion by the conscious dog. J Physiol (1987) 0.80
Effects of angiotensin-converting enzyme inhibition on altered renal hemodynamics induced by low protein diet in the rat. J Clin Invest (1987) 0.80
Effect of bumetanide, frusemide and prostaglandin E2 on the isolated perfused kidney of rat and rabbit. Br J Pharmacol (1984) 0.78
Tubular mechanisms determining the urinary excretion of tritiated prostaglandin E2 in the anaesthetized rat. J Physiol (1988) 0.78
Metabolomics profiling of the free and total oxidised lipids in urine by LC-MS/MS: application in patients with rheumatoid arthritis. Anal Bioanal Chem (2016) 0.77
Fruit and vegetable intake and urinary levels of prostaglandin E₂ metabolite in postmenopausal women. Nutr Cancer (2015) 0.76
Proceedings of the British Pharmacological Society. University of Dundee, 11th-14th September, 1984. Abstracts. Br J Pharmacol (1984) 0.75
Effect of tienoxolol, a new diuretic beta-blocking agent, on urinary prostaglandin excretion in the rat. Br J Pharmacol (1993) 0.75
Hypertrophic gastritis associated with increased gastric mucosal prostaglandin E2 concentrations in a patient with the carcinoid syndrome. Gut (1988) 0.75
Acute renal failure caused by nephrotoxins. Environ Health Perspect (1976) 0.75
Sulphinpyrazone in acute myocardial infarction. Br Med J (1980) 0.75
Effects of prostaglandin E2 on membrane voltage of the connecting tubule and cortical collecting duct from rabbits. J Physiol (1993) 0.75
PROSTAGLANDINS AND RELATED FACTORS: XIX. THIN-LAYER CHROMATOGRAPHY OF PROSTAGLANDINS. J Lipid Res (1964) 7.40
Kinetic parameters and renal clearances of plasma adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in man. J Clin Invest (1970) 2.18
Radioimmunoassay measurement of prostaglandins E, A, and F in human plasma. J Clin Invest (1973) 2.09
On the metabolism of prostaglandins E 1 and E 2 in man. J Biol Chem (1971) 1.71
The distribution of 15-hydroxy prostaglandin dehydrogenase and prostaglandin-delta 13-reductase in tissues of the swine. Acta Physiol Scand (1971) 1.60
Formation and release of prostaglandins by platelets in response to thrombin. Br J Pharmacol (1970) 1.59
PROSTAGLANDINS AND RELATED FACTORS. 28. METABOLISM OF PROSTAGLANDIN E1 IN GUINEA PIG LUNG: THE STRUCTURES OF TWO METABOLITES. J Biol Chem (1964) 1.56
Identification of prostaglandin E2 as the principal vasodepressor lipid of rabbit renal medulla. Nature (1967) 1.56
Relationship between endotoxin-induced abortion and the synthesis of prostaglandin F. Prostaglandins (1972) 1.43
Dependency of renal blood flow on prostaglandin synthesis in the dog. Circ Res (1973) 1.37
Human blood prostaglandins: formation during clotting. Prostaglandins (1972) 1.35
Interaction of prostaglandins with blood plasma proteins. Comparative binding of prostaglandins A 2 , F 2 and E 2 to human plasma proteins. Biochem J (1972) 1.32
Subcellular localization of the prostaglandin system in the rabbit renal papilla. Acta Physiol Scand (1972) 1.32
The effects of arachidonic acid, prostaglandin E2 and prostaglandin F2alpha on the longitudinal stomach strip of the rat. J Pharmacol Exp Ther (1973) 1.18
The metabolism of prostaglandin F2-alpha in the rat. Biochim Biophys Acta (1971) 1.00
Biosynthesis of prostaglandins in the renal medulla of rabbit. FEBS Lett (1969) 0.99
Analyses of prostaglandins in human semen. Prostaglandins and related factors 44. Clin Chim Acta (1966) 0.99
Distribution of prostaglandins in rabbit kidney. Biochem J (1970) 0.99
Measurement of urinary tryptamine, tyramine and serotonin. Methods Med Res (1961) 0.95
Mass spectrometric determination of picomole amounts of prostaglandins E 2 and F 2 using synthetic deuterium labeled carriers. Biochem Biophys Res Commun (1971) 0.92
Gas chromatographic determination of nanogram amounts of prostaglandins E and F. Prostaglandins (1973) 0.88
Quantitative determination of prostaglandins. Prostaglandins (1973) 0.88
The structure of a urinary metabolite of prostaglandin F2a in man. J Am Chem Soc (1969) 0.87
Quantitative vapor-phase analysis of prostaglandin F2 in female human urine. Prostaglandins (1973) 0.85
Characterization of prostaglandin E receptor in membranes and its use in the assay of prostaglandin E. Methods Enzymol (1974) 0.85
Display-oriented data system for multiple ion detection with gas chromatography-mass spectrometry in quantifying biomedically important compounds. Anal Chem (1973) 0.84
Urinary elimination of smooth muscle-acting prostaglandins in the dog. Arch Int Physiol Biochim (1971) 0.84
A competitive protein binding assay specific for prostaglandin E. Biochim Biophys Acta (1974) 0.83
Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med (2001) 18.91
Plasma propranolol levels in adults with observations in four children. Clin Pharmacol Ther (1970) 9.54
Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet (1998) 6.04
Childhood and adult socioeconomic status as predictors of mortality in Finland. Lancet (1994) 6.02
Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage. N Engl J Med (1995) 3.91
Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE. J Immunol (1982) 2.69
The relative efficacy of guanethidine, methyldopa and pargyline as antihypertensive agents. N Engl J Med (1965) 2.64
Prostaglandins as mediators of hypercalcemia associated with certain types of cancer. N Engl J Med (1975) 2.63
The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat. J Pharmacol Exp Ther (1973) 2.54
Effects of caffeine on plasma renin activity, catecholamines and blood pressure. N Engl J Med (1978) 2.50
Elevation of beta-adrenergic receptor density in human lymphocytes after propranolol administration. J Clin Invest (1980) 2.40
Coronary arterial smooth muscle contraction by a substance released from platelets: evidence that it is thromboxane A2. Science (1976) 2.39
Recommendations from the Canadian Hypertension Society Consensus Conference on Hypertension and Diabetes. CMAJ (1988) 2.36
Clinical experience over 48 years with pheochromocytoma. Ann Surg (1999) 2.32
Guanethidine and related agents. 3. Antagonism by drugs which inhibit the norepinephrine pump in man. J Clin Invest (1970) 2.29
Prevalence and predictors of white-coat response in patients with treated hypertension. CMAJ (1999) 2.26
Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor. Nat Med (1999) 2.26
The REMATCH trial: rationale, design, and end points. Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure. Ann Thorac Surg (1999) 2.26
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. Circulation (1997) 2.20
Estimated rate of prostacyclin secretion into the circulation of normal man. J Clin Invest (1981) 2.18
Sleep disorders in the elderly. Am J Psychiatry (1988) 2.17
Endogenous biosynthesis of prostacyclin and thromboxane and platelet function during chronic administration of aspirin in man. J Clin Invest (1983) 2.13
Novel fragmentation process of peptides by collision-induced decomposition in a tandem mass spectrometer: differentiation of leucine and isoleucine. Anal Chem (1987) 2.10
Radioimmunoassay for measurement of gentamicin in blood. Antimicrob Agents Chemother (1973) 2.08
Release of prostaglandin D2 into human airways during acute antigen challenge. N Engl J Med (1986) 2.03
Tolerance to the humoral and hemodynamic effects of caffeine in man. J Clin Invest (1981) 2.03
Modified continuous femoral three-in-one block for postoperative pain after total knee arthroplasty. Anesth Analg (1999) 1.92
Increased prescribing of antidepressants subsequent to beta-blocker therapy. Arch Intern Med (1990) 1.92
Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man. Circulation (1979) 1.88
Ionophores stimulate prostaglandin and thromboxane biosynthesis. Proc Natl Acad Sci U S A (1977) 1.82
Drought-induced guard cell signal transduction involves sphingosine-1-phosphate. Nature (2001) 1.79
Clinical pharmacology of propranolol. Circulation (1975) 1.79
Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. Circ Res (1988) 1.77
Severe allopurinol hypersensitivity. Association with thiazides and prior renal compromise. Arch Intern Med (1974) 1.76
Increased clearance of antipyrine and d-propranolol after phenobarbital treatment in the monkey. Relative contributions of enzyme induction and increased hepatic blood flow. J Clin Invest (1974) 1.74
Pharmacologic and endocrine aspects of carcinoid syndrome. Adv Pharmacol (1967) 1.74
The use of a surgical grade calcium sulfate as a bone graft substitute: results of a multicenter trial. Clin Orthop Relat Res (2001) 1.72
Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA (1967) 1.67
Contribution of kinins to endotoxin shock in unanesthetized Rhesus monkeys. Circ Res (1968) 1.66
Simultaneous measurement of cardiac output and its distribution with microspheres in the rat. Cardiovasc Res (1976) 1.66
Normal distribution of cardiac output in the unanesthetized, restrined rhesus monkey. J Appl Physiol (1968) 1.65
Increased production of prostaglandin D2 in patients with systemic mastocytosis. N Engl J Med (1980) 1.63
Suppression of plasma renin activity by indomethacin in man. Circ Res (1976) 1.62
Modulation of human neutrophil function by monohydroxy-eicosatetraenoic acids. Immunology (1980) 1.60
Direct measurement of propranolol bioavailability during accumulation to steady-state. Br J Clin Pharmacol (1978) 1.60
A novel methodology for assignment of disulfide bond pairings in proteins. Protein Sci (1997) 1.58
Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype. Br J Clin Pharmacol (1978) 1.57
Quantitative determination of guanethidine and other guanido-containing drugs in biological fluids by gas chromatography with flame ionization detection and multiple ion detection. Anal Chem (1974) 1.56
A new porcine bioprosthesis: in vitro and in vivo evaluation. Life Support Syst (1985) 1.55
Bartter's syndrome: a disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesis. Am J Med (1976) 1.55
Effect of oral prednisone on airway inflammatory mediators in atopic asthma. Am J Respir Crit Care Med (1994) 1.54
Early complications in the operative treatment of patella fractures. J Orthop Trauma (1997) 1.53
Time required for complete recovery from chronic propranolol therapy. N Engl J Med (1973) 1.51
Mechanism of antihypertensive action of ketanserin in man. Br Med J (Clin Res Ed) (1983) 1.47
Acute osteomyelitis in children. J Bone Joint Surg Br (1970) 1.47
Kinetics of the homogeneous freezing of water. Phys Chem Chem Phys (2010) 1.47
Reversibility of catecholamine-induced cardiomyopathy in a woman with pheochromocytoma. CMAJ (1989) 1.45
Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. Formation of 12-hydroxy-(9Z, 13E/Z, 15Z)- octadecatrienoic acids from alpha-linolenic acid. J Biol Chem (1995) 1.45
Chlorpromazine reversal of the antihypertensive action of guanethidine. Lancet (1971) 1.43
The hemodynamic effects of beta adrenergic blockade on the flow-dependent hepatic clearance of propranolol. J Pharmacol Exp Ther (1973) 1.43
Hypertension and fibromuscular dysplasia of the renal arteries. Surgery (1969) 1.42
Clinical failure of tibial interference screw fixation after anterior cruciate ligament reconstruction. A report of two cases. Am J Sports Med (1997) 1.40
Inhibition of monoamine oxidase in man by furazolidone. Clin Pharmacol Ther (1968) 1.40
How cells settle on glass: a study by light and scanning electron microscopy of some properties of normal and stimulated macrophages. Z Zellforsch Mikrosk Anat (1970) 1.40
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship. Br J Clin Pharmacol (1998) 1.39
(R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat Chem Biol (2011) 1.39
Prostaglandin thromboxane, and 12-hydroxy-5,8,10,14-eicosatetraenoic acid production by ionophore-stimulated rat serosal mast cells. Biochim Biophys Acta (1979) 1.39
Interscapular pain during cesarean delivery under epidural anesthesia. Int J Obstet Anesth (2010) 1.39
[Aspirin--yes, but 30 mg??]. Z Kardiol (1995) 1.39
Solubilization and properties of galactosyltransferase and sulfotransferase activities of Golgi membranes in Triton X-100. J Biol Chem (1978) 1.39
Inhibition of eicosanoid biosynthesis by glucocorticoids in humans. Proc Natl Acad Sci U S A (1990) 1.38
Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome. N Engl J Med (1978) 1.37
Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars. J Oral Maxillofac Surg (1995) 1.36
Biosynthesis of prostaglandin D2. 1. Formation of prostaglandin D2 by human platelets. Prostaglandins (1977) 1.36
Endothelium-derived relaxing factor from cultured human endothelial cells inhibits aggregation of human platelets. Thromb Res (1987) 1.35
Metabolism of thromboxane B2 in man. Identification of twenty urinary metabolites. J Biol Chem (1981) 1.35
Altered hepatic blood flow and drug disposition. Clin Pharmacokinet (1976) 1.34
Quantification of the major urinary metabolite of 15-F2t-isoprostane (8-iso-PGF2alpha) by a stable isotope dilution mass spectrometric assay. Anal Biochem (1999) 1.34
Relation between plasma concentration of indomethacin and its effect on prostaglandin synthesis and platelet aggregation in man. Clin Pharmacol Ther (1978) 1.33
Blockade of the flush associated with metastatic gastric carcinoid by combined histamine H1 and H2 receptor antagonists. Evidence for an important role of H2 receptors in human vasculature. N Engl J Med (1979) 1.32
Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease. J Am Soc Nephrol (1999) 1.32
Binge drinking among undergraduate college students in the United States: implications for other substance use. J Am Coll Health (2001) 1.32