Published in Arch Virol Suppl on January 01, 2000
Caspase-12 and endoplasmic reticulum stress mediate neurotoxicity of pathological prion protein. EMBO J (2003) 2.34
Stressing out the ER: a role of the unfolded protein response in prion-related disorders. Curr Mol Med (2006) 1.49
Transmission of prions. Proc Natl Acad Sci U S A (2002) 1.36
Prion peptide induces neuronal cell death through a pathway involving glycogen synthase kinase 3. Biochem J (2003) 1.11
Theoretical modeling of prion disease incubation. Biophys J (2003) 0.91
Human PrP90-231-induced cell death is associated with intracellular accumulation of insoluble and protease-resistant macroaggregates and lysosomal dysfunction. Cell Death Dis (2011) 0.86
Immunopurification of pathological prion protein aggregates. PLoS One (2009) 0.86
Seeded fibrillation as molecular basis of the species barrier in human prion diseases. PLoS One (2013) 0.82
Helper T cell differentiation is controlled by the cell cycle. Immunity (1998) 5.71
Viroids are single-stranded covalently closed circular RNA molecules existing as highly base-paired rod-like structures. Proc Natl Acad Sci U S A (1976) 3.58
Trehalose expression confers desiccation tolerance on human cells. Nat Biotechnol (2000) 2.98
Temperature-gradient gel electrophoresis. Thermodynamic analysis of nucleic acids and proteins in purified form and in cellular extracts. Biophys Chem (1987) 2.91
Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J Exp Med (1997) 2.81
Patterns and correlates of physical activity among US women 40 years and older. Am J Public Health (2000) 2.79
Mismatches in DNA double strands: thermodynamic parameters and their correlation to repair efficiencies. Nucleic Acids Res (1986) 2.73
Promoting physical activity in rural communities: walking trail access, use, and effects. Am J Prev Med (2000) 2.65
Scrapie prion proteins are synthesized in neurons. Am J Pathol (1986) 2.54
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain. J Neurosci (2000) 2.49
Genetic influence on the structural variations of the abnormal prion protein. Proc Natl Acad Sci U S A (2000) 2.46
Molecular cloning of a human prion protein cDNA. DNA (1986) 2.43
Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Ann Neurol (1998) 2.35
Monocyte/macrophage differentiation in early multiple sclerosis lesions. Ann Neurol (1995) 2.34
Psychological monitoring of overtraining and staleness. Br J Sports Med (1987) 2.33
The conformational transitions in yeast tRNAPhe as studied with tRNAPhe fragments. Eur J Biochem (1973) 2.26
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment. Nature (1996) 2.20
Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study. BMJ (1998) 2.15
Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings. Neurology (2004) 2.15
Conformational transitions in viroids and virusoids: comparison of results from energy minimization algorithm and from experimental data. J Biomol Struct Dyn (1984) 2.14
Structure and structure formation of viroids. J Mol Biol (1979) 2.03
Reliability of information on physical activity and other chronic disease risk factors among US women aged 40 years or older. Am J Epidemiol (1999) 1.97
Replacement of bovine mitochondrial DNA by a sequence variant within one generation. Genetics (1991) 1.96
Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies. Brain (2004) 1.96
Viroids. Annu Rev Biochem (1985) 1.93
The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases. Am J Pathol (2000) 1.91
Diagnosis of Creutzfeldt-Jakob disease by two-dimensional gel electrophoresis of cerebrospinal fluid. Lancet (1996) 1.91
Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy. Nat Med (1998) 1.89
Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt. Genomics (1996) 1.89
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp. J Virol (2001) 1.86
Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology (2002) 1.84
Viroids: a class of subviral pathogens. Angew Chem Int Ed Engl (1980) 1.81
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model. Am J Pathol (2001) 1.81
Analysis of the systemic and intrathecal humoral immune response in progressive multifocal leukoencephalopathy. J Infect Dis (1997) 1.79
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity. Exp Neurol (1997) 1.78
Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves. J Virol (2001) 1.73
Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. Neurosci Lett (1997) 1.71
How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain (1999) 1.71
Cloning of the filamentous hemagglutinin of Bordetella pertussis and its expression in Escherichia coli. Infect Immun (1987) 1.69
Identification of a chromosomal determinant of alpha-toxin production in Staphylococcus aureus. Infect Immun (1980) 1.65
Sporadic Creutzfeldt-Jakob disease: clinical and diagnostic characteristics of the rare VV1 type. Neurology (2005) 1.65
Intraoperative ventilator settings and acute lung injury after elective surgery: a nested case control study. Thorax (2008) 1.64
A two-dimensional electrophoretic technique for the detection of circular viroids and virusoids. Anal Biochem (1983) 1.63
Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity. Neurology (1991) 1.61
Protective vaccination with a recombinant fragment of Clostridium botulinum neurotoxin serotype A expressed from a synthetic gene in Escherichia coli. Infect Immun (1995) 1.61
Subcellular localization of viroids in highly purified nuclei from tomato leaf tissue. EMBO J (1983) 1.59
Breath hydrogen excretion as a screening test for the early diagnosis of necrotizing enterocolitis. Am J Dis Child (1989) 1.58
Creutzfeldt-Jakob disease in Germany: a prospective 12-year surveillance. Brain (2007) 1.56
[The Creutzfeld-Jakob disease. A sphinx of current neurobiology]. Dtsch Med Wochenschr (1997) 1.55
Molecular genetics of human prion diseases in Germany. Hum Genet (1999) 1.53
Viroid processing: switch from cleavage to ligation is driven by a change from a tetraloop to a loop E conformation. EMBO J (1997) 1.52
Impact on process of trauma care delivery 1 year after the introduction of a trauma program in a provincial trauma center. J Trauma (1999) 1.52
Transmission of Creutzfeldt-Jakob disease by handling of dura mater. Lancet (1993) 1.52
Effect of leptin deficiency on metabolic rate in ob/ob mice. Am J Physiol (1999) 1.51
An improved in vitro pyrogen test: to detect picograms of endotoxin contamination in intravenous fluids using limulus amoebocyte lysate. J Lab Clin Med (1977) 1.50
Role of microglia in neuronal cell death in prion disease. Brain Pathol (1998) 1.49
Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants. Ann Neurol (2000) 1.49
Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study. Neurology (2004) 1.45
Multiple pathways of reversion in viroids for conservation of structural elements. EMBO J (1993) 1.44
Hand-held portable sonography for the on-mountain exclusion of a pneumothorax. Wilderness Environ Med (2001) 1.43
Mouse model of sublethal and lethal intraperitoneal glanders (Burkholderia mallei). Vet Pathol (2000) 1.43
Sequence determination of human papillomavirus type 6a and assembly of virus-like particles in Saccharomyces cerevisiae. Virology (1995) 1.43
RNA aptamers specifically interact with the prion protein PrP. J Virol (1997) 1.43
Imaging of viroids in nuclei from tomato leaf tissue by in situ hybridization and confocal laser scanning microscopy. EMBO J (1989) 1.41
Analysis of bacteriophage phi X174 gene A protein-mediated termination and reinitiation of phi X DNA synthesis. II. Structural characterization of the covalent phi X A protein-DNA complex. J Biol Chem (1984) 1.41
A multicomponent program for nutrition and physical activity change in primary care: PACE+ for adolescents. Arch Pediatr Adolesc Med (2001) 1.40
Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells. Proc Natl Acad Sci U S A (2001) 1.39
Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry (2001) 1.39
Formation of a thermodynamically metastable structure containing hairpin II is critical for infectivity of potato spindle tuber viroid RNA. EMBO J (1991) 1.38
Cephalexin-supplemented Jones-Kendrick charcoal agar for selective isolation of Bordetella pertussis: comparison with previously described media. J Clin Microbiol (1983) 1.37
Transcriptional activation of the human epidermal growth factor receptor promoter by human p53. Mol Cell Biol (1996) 1.37
C-MYC expression in medulloblastoma and its prognostic value. Int J Cancer (2000) 1.37
The Heidenhain variant of Creutzfeldt-Jakob disease. Arch Neurol (1999) 1.37
Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas. Neuro Oncol (2011) 1.35
Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies. Acta Neuropathol (2000) 1.33
Aberrant metal binding by prion protein in human prion disease. J Neurochem (2001) 1.33
Neutralization of human papillomavirus (HPV) pseudovirions: a novel and efficient approach to detect and characterize HPV neutralizing antibodies. Virology (2000) 1.31
Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities. J Neurochem (2001) 1.30
Equivalent and non-equivalent binding sites for tRNA on aminoacyl-tRNA synthetases. Eur J Biochem (1975) 1.29
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease. EMBO J (2001) 1.29
Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study. J Med Genet (2006) 1.28
Perceived barriers to exercise and stage of exercise adoption in older women of different racial/ethnic groups. Women Health (2000) 1.28
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment. Neuroreport (1994) 1.27
The use of quaternary narcotic antagonists in opiate research. Neuropharmacology (1985) 1.27
RNA structure and the regulation of gene expression. Plant Mol Biol (1996) 1.27
Detection of PrP(Sc) in subclinical BSE with the paraffin-embedded tissue (PET) blot. Arch Virol Suppl (2000) 1.27
Support for policy interventions to increase physical activity in rural Missouri. Am J Health Promot (1998) 1.26
Effects of copper on survival of prion protein knockout neurons and glia. J Neurochem (1998) 1.26
The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs. Proc Natl Acad Sci U S A (1993) 1.26
Analysis of RNA structures by temperature-gradient gel electrophoresis: viroid replication and processing. Gene (1988) 1.25
S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease. J Neurol (1997) 1.24
Fatal familial insomnia: a new Austrian family. Brain (1999) 1.24
Pattern of cortical changes in sporadic Creutzfeldt-Jakob disease. AJNR Am J Neuroradiol (2007) 1.24
Further analysis of nucleic acids in purified scrapie prion preparations by improved return refocusing gel electrophoresis. J Gen Virol (1992) 1.23
Human papillomavirus genotypes associated with cervical cytologic abnormalities and HIV infection in Ugandan women. J Med Virol (2007) 1.23
Thermodynamic prediction of conserved secondary structure: application to the RRE element of HIV, the tRNA-like element of CMV and the mRNA of prion protein. J Mol Biol (1996) 1.22
The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice. J Neurosci (2001) 1.22
Limits in reliability of glycoprotein G-based type-specific serologic assays for herpes simplex virus types 1 and 2. J Clin Microbiol (1999) 1.22
Common structural features of different viroids: serial arrangement of double helical sections and internal loops. Nucleic Acids Res (1978) 1.22