Structure and mechanism in NF-kappa B/I kappa B signaling.

Control of NF-kappaB-dependent transcriptional responses by chromatin organization. Cold Spring Harb Perspect Biol (2009) 1.67

Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure. Cardiovasc Res (2010) 1.45

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha. Proc Natl Acad Sci U S A (2009) 1.39

Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha. Biochemistry (2010) 1.25

X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. J Mol Biol (2007) 1.01

Anti-inflammatory cytokines: important immunoregulatory factors contributing to chemotherapy-induced gastrointestinal mucositis. Chemother Res Pract (2012) 0.95

Inactivation of NF-kappaB-dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl. Mol Cell Biol (2002) 0.92

Transcriptional control of inflammatory responses. Cold Spring Harb Perspect Biol (2014) 0.91

The RelA nuclear localization signal folds upon binding to IκBα. J Mol Biol (2010) 0.89

Systemic lupus erythematosus and increased risk to develop B cell malignancies: role of the p200-family proteins. Immunol Lett (2010) 0.86

Resolution of Inflammation: What Controls Its Onset? Front Immunol (2016) 0.84

Identification of novel small molecule activators of nuclear factor-κB with neuroprotective action via high-throughput screening. J Neurosci Res (2011) 0.83

Single-molecule FRET reveals the native-state dynamics of the IκBα ankyrin repeat domain. J Mol Biol (2013) 0.83

N-acetyl-L-cysteine sensitizes pancreatic cancers to gemcitabine by targeting the NFκB pathway. Biomed Pharmacother (2014) 0.79

p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation. Proc Natl Acad Sci U S A (2014) 0.78

Structural modeling of the N-terminal signal-receiving domain of IκBα. Front Mol Biosci (2015) 0.75

miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression. Proc Natl Acad Sci U S A (2017) 0.75

The crystal structure of the IkappaBalpha/NF-kappaB complex reveals mechanisms of NF-kappaB inactivation. Cell (1998) 4.71

Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature (1998) 4.03

Transcriptional regulation via the NF-kappaB signaling module. Oncogene (2006) 3.92

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway. Proc Natl Acad Sci U S A (2000) 3.89

The structure of Sky1p reveals a novel mechanism for constitutive activity. Nat Struct Biol (2001) 2.10

Regulation of DNA binding by Rel/NF-kappaB transcription factors: structural views. Oncogene (1999) 2.04

Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J Mol Biol (1996) 1.87

The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box. Proc Natl Acad Sci U S A (1997) 1.82

Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol (1998) 1.77

A novel DNA recognition mode by the NF-kappa B p65 homodimer. Nat Struct Biol (1998) 1.68

The sensitivity, specificity and predictive values of raised plasma metal ion levels in the diagnosis of adverse reaction to metal debris in symptomatic patients with a metal-on-metal arthroplasty of the hip. J Bone Joint Surg Br (2012) 1.62

IkappaBbeta, but not IkappaBalpha, functions as a classical cytoplasmic inhibitor of NF-kappaB dimers by masking both NF-kappaB nuclear localization sequences in resting cells. J Biol Chem (2001) 1.48

Assessing the 'cyclodiode G-probe' using a grey scale test: reproducibility and differences between probes. Eye (Lond) (2003) 1.39

Mechanism of kappa B DNA binding by Rel/NF-kappa B dimers. J Biol Chem (2000) 1.36

Construction, expression, purification and functional analysis of recombinant NFkappaB p50/p65 heterodimer. Protein Eng (1999) 1.36

Muscle fatigue and pain after eccentric contractions at long and short length. Clin Sci (Lond) (1988) 1.35

Ikappa Balpha functions through direct contacts with the nuclear localization signals and the DNA binding sequences of NF-kappaB. J Biol Chem (1998) 1.33

Mechanism of I kappa B alpha binding to NF-kappa B dimers. J Biol Chem (2000) 1.33

Do locally agreed guidelines for optometrists concerning the referral of glaucoma suspects influence referral practice? Eye (Lond) (2001) 1.31

X-ray crystal structure of proto-oncogene product c-Rel bound to the CD28 response element of IL-2. Structure (2001) 1.22

The status of local smoking regulations in North Carolina following a state preemption bill. JAMA (1995) 1.17

In-vitro studies with ramoplanin (MDL 62,198): a novel lipoglycopeptide antimicrobial. J Antimicrob Chemother (1990) 1.16

NF-kappaB p65 (RelA) homodimer uses distinct mechanisms to recognize DNA targets. Structure (2000) 1.13

Structure of a G.T.A triplet in an intramolecular DNA triplex. Biochemistry (1992) 1.09

Resistance studies with ofloxacin. J Antimicrob Chemother (1988) 1.04

A prospective study of the effect of I.V. pentamidine therapy on ventricular arrhythmias and QTc prolongation in HIV-infected patients. Chest (1997) 0.97

The role of DNA in the mechanism of NFkappaB dimer formation: crystal structures of the dimerization domains of the p50 and p65 subunits. Structure (1997) 0.97

Characterization of the dimer interface of transcription factor NFkappaB p50 homodimer. J Mol Biol (1999) 0.97

Severe diabetic retinopathy in adolescents. Br J Ophthalmol (1983) 0.91

Structure and stability of X.G.C mismatches in the third strand of intramolecular triplexes. Science (1991) 0.91

The relationship between synthetic and editing functions of the active site of an aminoacyl-tRNA synthetase. Proc Natl Acad Sci U S A (1993) 0.90

Analysis of differentially expressed genes in hyperthyroid-induced hypertrophied heart by cDNA microarray. J Endocrinol (2004) 0.87

Buckling-driven morphological transformation of droplets of a mixed colloidal suspension during evaporation-induced self-assembly by spray drying. Eur Phys J E Soft Matter (2010) 0.86

Preparation and crystallization of dynamic NF-kappa B.Ikappa B complexes. J Biol Chem (2000) 0.84

Congenital fibrosis of superior rectus and superior oblique: a case report. Br J Ophthalmol (1985) 0.84

An in vitro characterization of cefditoren, a new oral cephalosporin. Drugs Exp Clin Res (1994) 0.83

AAV-P125A-endostatin and paclitaxel treatment increases endoreduplication in endothelial cells and inhibits metastasis of breast cancer. Gene Ther (2010) 0.83

Decision making for knee replacement: variation in treatment choice for late stage medial compartment osteoarthritis. Knee (2012) 0.82

Early organ-specific hemorrhage-induced increases in tissue cytokine content: associated neurohormonal and opioid alterations. Neuroimmunomodulation (1997) 0.82

Conference on insulin pump therapy in diabetes. Multicenter study of effect on microvascular disease. Assessment of fluorescein angiograms. Diabetes (1985) 0.82

Sellmeier coefficients and dispersion of thermo-optic coefficients for some optical glasses. Appl Opt (1997) 0.81

Actin-like protein from Mimosa pudica L. Indian J Biochem Biophys (1987) 0.79

Advanced wear of an Oxinium™ femoral head implant following polyethylene liner dislocation. Ann R Coll Surg Engl (2013) 0.78

[Cardiogenic shock in the acute phase of myocardial infarction]. Tunis Med (2000) 0.75

Splenic tuberculosis--a case report. J Indian Med Assoc (1998) 0.75

Sellmeier Coefficients for the Birefringence and Refractive Indices of ZnGeP(2) Nonlinear Crystal at Different Temperatures. Appl Opt (1998) 0.75

S approximation for light scattering by an infinitely long cylinder. Appl Opt (1997) 0.75

Coefficients of a Dispersion Equation for the Birefringence of a CdGeAs(2) Nonlinear Crystal at Different Temperatures. Appl Opt (1998) 0.75

Sweat gland carcinoma - a case report. J Indian Med Assoc (2010) 0.75

Evaporation-induced self assembly of nanoparticles in non-buckling regime: volume fraction dependent packing. J Colloid Interface Sci (2010) 0.75

Klippel-Trenaunnay-Weber syndrome. Indian Pediatr (1998) 0.75

[Dumesnil's method: is it viable?]. Tunis Med (2001) 0.75

Disc diffusion susceptibility testing with ceftriaxone. J Antimicrob Chemother (1994) 0.75

Dispersion of temperature coefficients of birefringence in some chalcopyrite crystals. Appl Opt (1984) 0.75

[Dual chamber pacing in hypertrophic obstructive cardiomyopathy]. Tunis Med (1998) 0.75

Thermo-optic coefficients of LiNbO(3), LiIO(3), and LiTaO(3) nonlinear crystals. Opt Lett (1994) 0.75

[Sinus node dysfunction after complete correction of tetralogy of Fallot. Report of a case]. Arch Mal Coeur Vaiss (1998) 0.75

Water supply in Calcutta in relation to cholera. Indian J Med Res (1965) 0.75

Peritoneal graft as conjunctival replacement. Indian J Ophthalmol (1981) 0.75