PubRank

A Zimmer

Author PubWeight™ 180.23‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The transcriptional landscape of the mammalian genome. Science 2005 37.63
2 Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature 2002 28.79
3 Genome-wide, large-scale production of mutant mice by ENU mutagenesis. Nat Genet 2000 3.92
4 Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat Med 1998 3.75
5 Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc Natl Acad Sci U S A 1999 3.54
6 Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. Eur J Pharmacol 2000 2.83
7 Endothelial apoptosis in Braf-deficient mice. Nat Genet 1997 2.77
8 Sequence interpretation. Functional annotation of mouse genome sequences. Science 2001 2.54
9 Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin. Nature 1996 2.17
10 Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. J Neurochem 2000 2.04
11 The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development 1994 1.98
12 Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J Biol Chem 2000 1.78
13 MouseBank: a database application for managing transgenic mouse breeding programs. Biotechniques 2001 1.42
14 [Idiopathic facial palsy during pregnancy]. HNO 2012 1.38
15 A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents. Br J Pharmacol 2010 1.32
16 Gene-gene effects on central processing of aversive stimuli. Mol Psychiatry 2007 1.32
17 The patched signaling pathway in tumorigenesis and development: lessons from animal models. J Mol Med (Berl) 1999 1.29
18 POU transcription factors control expression of CNS stem cell-specific genes. Development 1998 1.28
19 CB2 receptors as new therapeutic targets for liver diseases. Br J Pharmacol 2007 1.24
20 Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis. Mech Dev 2000 1.23
21 Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech Dev 1996 1.20
22 Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotype. J Neural Transm (Vienna) 2007 1.19
23 Regulation of RAR beta 2 mRNA expression: evidence for an inhibitory peptide encoded in the 5'-untranslated region. J Cell Biol 1996 1.18
24 Dysregulated cannabinoid signaling disrupts uterine receptivity for embryo implantation. J Biol Chem 2001 1.14
25 Craf-1 protein kinase is essential for mouse development. Mech Dev 1998 1.09
26 Activity of the beta-retinoic acid receptor promoter in transgenic mice. Mech Dev 1991 1.08
27 [Pharmacokinetics and metabolism of trazodone in man (author's transl)]. Arzneimittelforschung 1976 1.07
28 Cardiovascular effects of 2-arachidonoyl glycerol in anesthetized mice. Hypertension 2000 1.06
29 Dose-related opposite modulation by nociceptin/orphanin FQ of substance P nociception in the nociceptors and spinal cord. J Pharmacol Exp Ther 1999 1.05
30 Antisense delivery using protamine-oligonucleotide particles. Nucleic Acids Res 2000 1.05
31 [Single and multiple applications and metabolite pattern of clenbuterol in man (author's transl)]. Arzneimittelforschung 1976 1.04
32 Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice. Proc Natl Acad Sci U S A 1999 1.04
33 Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoter. Mol Cell Biol 1997 1.03
34 Endocannabinoids and the regulation of bone metabolism. J Neuroendocrinol 2008 1.02
35 Pharmacokinetics and metabolite-pattern of 8-methoxypsoralen in man following oral administration as compared to the pharmacokinetics in rat and dog. Arch Dermatol Res 1978 1.01
36 The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. Curr Pharm Biotechnol 2009 1.01
37 Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study. Mol Psychiatry 2008 1.01
38 Tetanus toxin light chain expression in Sertoli cells of transgenic mice causes alterations of the actin cytoskeleton and disrupts spermatogenesis. EMBO J 1993 1.00
39 Isolation and characterization of two human H1 histone genes within clusters of core histone genes. Genomics 1991 1.00
40 Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. Proc Natl Acad Sci U S A 2005 0.99
41 Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice. J Neurosci 2000 0.97
42 Nociceptin/orphanin FQ-induced nociceptive responses through substance P release from peripheral nerve endings in mice. Proc Natl Acad Sci U S A 1998 0.96
43 Enhanced acetylcholine release in the hippocampus of cannabinoid CB(1) receptor-deficient mice. Br J Pharmacol 2001 0.94
44 Agonist efficacy and receptor efficiency in heterozygous CB1 knockout mice: relationship of reduced CB1 receptor density to G-protein activation. J Neurochem 2001 0.94
45 Mapping of the lingual immune system reveals the presence of both regulatory and effector CD4+ T cells. Clin Exp Allergy 2009 0.93
46 Region selective up-regulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice. Neuroscience 2003 0.93
47 Hyperperfusion syndrome after carotid stent angioplasty. Neuroradiology 2008 0.92
48 Reduced availability of serotonin transporters in obsessive-compulsive disorder correlates with symptom severity - a [11C]DASB PET study. J Neural Transm (Vienna) 2007 0.92
49 Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age. Diabetologia 2010 0.92
50 Analysis of the endocannabinoid system by using CB1 cannabinoid receptor knockout mice. Handb Exp Pharmacol 2005 0.91
51 Protective role of palmitoylethanolamide in contact allergic dermatitis. Allergy 2009 0.91
52 Cannabinoid receptors and the regulation of bone mass. Br J Pharmacol 2007 0.91
53 Development of an itraconazole-loaded nanostructured lipid carrier (NLC) formulation for pulmonary application. Int J Pharm 2011 0.90
54 Fully automated high-performance liquid chromatography. A new chromatograph for pharmacokinetic drug monitoring by direct injection of body fluids. J Chromatogr 1981 0.90
55 Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice. Mucosal Immunol 2011 0.90
56 Impact of drying on solid state modifications and drug distribution in ibuprofen-loaded calcium stearate pellets. Mol Pharm 2014 0.88
57 Use of liposomes, viral capsids, and nanoparticles as DNA carriers. Biotechnol Appl Biochem 1991 0.88
58 Room for improvement: nurses' and physicians' views of a post-operative pain management program. Acta Anaesthesiol Scand 2009 0.87
59 Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part II: characterization of antisense oligonucleotides loaded copolymer nanoparticles. Eur J Pharm Biopharm 1999 0.86
60 Induction of a RAR beta 2-lacZ transgene by retinoic acid reflects the neuromeric organization of the central nervous system. Development 1992 0.86
61 Oligonucleotide and plasmid DNA packaging into polyoma VP1 virus-like particles expressed in Escherichia coli. Biotechnol Appl Biochem 1999 0.85
62 Preprodynorphin mediates locomotion and D2 dopamine and mu-opioid receptor changes induced by chronic 'binge' cocaine administration. J Neurochem 2007 0.84
63 Phosphodiester and phosphorothioate oligonucleotide condensation and preparation of antisense nanoparticles. Biochim Biophys Acta 2001 0.84
64 Preproenkephalin is a Th2 cytokine but is not required for Th2 differentiation in vitro. Immunol Cell Biol 1999 0.84
65 Understanding mammary gland development through the imbalanced expression of growth regulators. Dev Dyn 1996 0.84
66 Liposomal oxytetracycline and doxycycline: studies on enhancement of encapsulation efficiency. Drug Discov Ther 2009 0.83
67 Region-specific up-regulation of opioid receptor binding in enkephalin knockout mice. Brain Res Mol Brain Res 1999 0.83
68 The murine homeo box gene product, Hox 1.1 protein, is growth-controlled and associated with chromatin. Differentiation 1987 0.83
69 Redistribution of nuclear lamins in mitotic cells. Biol Cell 1986 0.82
70 Evaluation of aminoalkylmethacrylate nanoparticles as colloidal drug carrier systems. Part I: Synthesis of monomers, dependence of the physical properties on the polymerization methods. Eur J Pharm Biopharm 1999 0.81
71 Targeted reduction of oxytocin expression provides insights into its physiological roles. Adv Exp Med Biol 1998 0.81
72 Studies on molecular interactions between nalidixic acid and liposomes. Int J Pharm 2004 0.81
73 Gene targeting and behaviour: a genetic problem requires a genetic solution. Trends Neurosci 1996 0.80
74 [Pharmacokinetics and metabolite pattern of clenbuterol in the rat]. Arzneimittelforschung 1976 0.80
75 Tissue-specific expression of tomato Ribonuclease LX during phosphate starvation-induced root growth. J Exp Bot 2006 0.79
76 Nanoparticle-mediated treatment of pulmonary arterial hypertension. Methods Enzymol 2012 0.79
77 Cationic polyhexylcyanoacrylate nanoparticles as carriers for antisense oligonucleotides. Antisense Nucleic Acid Drug Dev 1997 0.79
78 Absence of the interstitial cell of Cajal network in mitochondrial neurogastrointestinal encephalomyopathy. Neurogastroenterol Motil 2009 0.79
79 An European Organisation for Research and Treatment of Cancer phase I study of lapatinib and docetaxel as neoadjuvant treatment for human epidermal growth factor receptor 2 (HER2) positive locally-advanced/inflammatory or large operable breast cancer. Eur J Cancer 2012 0.79
80 Physicochemical characterization of protamine-phosphorothioate nanoparticles. J Microencapsul 2004 0.79
81 Glutathione peroxidase isoenzymes in human tumor cell lines. Pharmazie 2011 0.78
82 Basic molecular fingerprinting of immature cerebellar cortical inhibitory interneurons and their precursors. Neuroscience 2008 0.78
83 [Sturge-Weber syndrome]. Radiologe 2013 0.78
84 Endocannabinoid receptor deficiency affects maternal care and alters the dam's hippocampal oxytocin receptor and brain-derived neurotrophic factor expression. J Neuroendocrinol 2013 0.78
85 Effect of chronic corticosterone application on depression-like behavior in C57BL/6N and C57BL/6J mice. Genes Brain Behav 2015 0.78
86 Interspecies fluorescence in situ hybridization further defines synteny homology between mouse chromosome 11 and human chromosome 17. Mamm Genome 1995 0.78
87 Enhanced antisense efficacy of oligonucleotides adsorbed to monomethylaminoethylmethacrylate methylmethacrylate copolymer nanoparticles. Eur J Pharm Biopharm 2000 0.77
88 Gene targeting constructs: effects of vector topology on co-expression efficiency of positive and negative selectable marker genes. Biochem Biophys Res Commun 1994 0.77
89 Increased morphine analgesia and reduced side effects in mice lacking the tac1 gene. Br J Pharmacol 2010 0.77
90 Quantitative autoradiography of adenosine receptors and NBTI-sensitive adenosine transporters in the brains of mice deficient in the preproenkephalin gene. Brain Res 2004 0.77
91 Enkephalin release and opioid receptor activation does not mediate the antinociceptive or sedative/hypnotic effects of nitrous oxide. Eur J Pharmacol 2001 0.77
92 Mutagenesis and knockout models: NK1 and substance P. Handb Exp Pharmacol 2005 0.77
93 Smad-interacting protein 1 affects acute and tonic, but not chronic pain. Eur J Pain 2013 0.77
94 Microsomal epoxide hydrolase in different rat strains. Biochem Pharmacol 1983 0.77
95 Enkephalin knockout male mice are resistant to chronic mild stress. Genes Brain Behav 2014 0.77
96 [Selected properties of lactose-fermenting and non-fermenting Salmonella agona strains isolated from specimens from hospitalized infants]. Med Dosw Mikrobiol 1989 0.76
97 Chronic nicotine improves short-term memory selectively in a G72 mouse model of schizophrenia. Br J Pharmacol 2014 0.76
98 Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles. Pharm Res 2000 0.76
99 Th2-dependent airway eosinophilia is regulated by preproenkephalin. J Neuroimmunol 2000 0.76
100 Investigation of the pharmacodynamics and pharmacokinetics of 2-(2,4-dimethoxyphenyl)-Imidazo-(4,5-b)-pyridine hydrochloride (AR-L 57 CL) in man. Eur J Clin Pharmacol 1976 0.76
101 Effect of ultrasonication on the stability of oligonucleotides adsorbed on nanoparticles and liposomes. J Microencapsul 1999 0.75
102 Controlled release implants based on cast lipid blends. Eur J Pharm Sci 2011 0.75
103 Anti-inflammatory activity of sublingual immunoglobulin (SLIG) in a murine model of allergen-driven airway inflammation. Vaccine 2012 0.75
104 [AR-L 115 BS, comparison of human metabolite pattern and biotransformation with other species]. Arzneimittelforschung 1981 0.75
105 [Studies on the biotransformation of fominoben-HCl in man (author's transl)]. Arzneimittelforschung 1978 0.75
106 [Carotid artery stenosis: current state of therapy]. Radiologe 2010 0.75
107 [Excretion and metabolic pattern of fominoben in the urine and feces of man rabbit, dog, and rat]. Arzneimittelforschung 1973 0.75
108 Pharmacokinetics of a novel liquid controlled release codeine formulation. Drug Dev Ind Pharm 2011 0.75
109 [Dependence of lactate and heart rate in ergometer-, running- and swimming stress and its use for the preparation of individual conditioning programs for patients with myocardial infarct in rehabilitation phase III]. Z Gesamte Inn Med 1977 0.75
110 [Pharmacokinetic comparison of clobutinol HCl (with and without orciprenaline SO4) in solution, juice and syrup in man]. Arzneimittelforschung 1977 0.75
111 [Pharmacokinetics of fominoben-HCl in the dog and the rabbit (author's transl)]. Arzneimittelforschung 1979 0.75
112 Metabolism of p-fluorophenylalanine in p-fluorophenylalanine sensitive and resistant tobacco cell cultures. Planta 1982 0.75
113 [Dependence of lactate on pulse rate, performance and cardiac volume performance quotient in rehabilitated myocardial infarct patients during bicycle ergometry]. Z Gesamte Inn Med 1977 0.75
114 Fluorescence correlation spectroscopy for the characterisation of drug delivery systems. Biol Chem 2001 0.75
115 [Pharmacokinetics of oxiethyltheophylline and fominoben hydrochloride in man (author's transl)]. Arzneimittelforschung 1978 0.75
116 Do we see what makes our script characteristic-- -or do we only feel it? Modes of sensory control in handwriting. Psychol Res 1982 0.75
117 [Pharmacokinetics and metabolite pattern of clenbuterol in rabbit and dog (author's transl)]. Arzneimittelforschung 1976 0.75
118 [Comparison of the pharmacokinetic profiles of clenbuterol in rat and dog during toxicological studies (author's transl)]. Arzneimittelforschung 1976 0.75
119 [And if we speak of continuing education!]. Schweiz Monatsschr Zahnmed 1995 0.75
120 Effect of Ru-Mn redox interactions on the hole carrier density in pulsed electron deposited La(1-x)Pb(x)Mn(0.8)Ru(0.2)O(3) (0.2≤x≤0.4) thin films. J Phys Condens Matter 2008 0.75
121 [Radio synthesis of 14C-2-[(2-Methoxy-4-methyl-sulfinyl)phenyl]-1H-imidazo[4,5-b]pyridine (AR-L 115 BS) (author's transl)]. Arzneimittelforschung 1981 0.75
122 Reduced activity of BRAF protein kinase in hop and hop(hpy) mouse mutants. Mamm Genome 1998 0.75
123 Simultaneous labelling with stable and radioactive isotopes in drug metabolism studies. Biochem Pharmacol 1973 0.75
124 [Pharmacokinetic studies on fluoro-alpha-acetyl-digoxin (author's transl)]. Arzneimittelforschung 1978 0.75
125 The neuroradiology of melanomas of the central nervous system. Am J Roentgenol Radium Ther Nucl Med 1967 0.75
126 [Imaging in carcinoma of the upper respiratory tract. TNM classification of neoplastic lesions]. Radiologe 2011 0.75
127 [Differential diagnosis of non-neoplastic space-occupying lesions of the spinal cord]. Radiologe 2006 0.75
128 Protonation products of pentaaminopentane as novel building blocks for hydrogen-bonded networks. Acta Crystallogr C 2000 0.75
129 [Pharmacokinetics and metabolism of fominoben (Noleptan) in man]. Arzneimittelforschung 1973 0.75
130 [Dentistry, a liberal profession--dream or reality?]. Schweiz Monatsschr Zahnmed 2000 0.75
131 Fractionation of tRNA on hydroxyapatite. Bull Soc Chim Biol (Paris) 1970 0.75
132 Planning and executing fast movement sequences: a comparison of speech and handwriting. Res Q Exerc Sport 1999 0.75
133 Hypoxic ventilatory response in Tac1-/- neonatal mice following exposure to opioids. J Appl Physiol (1985) 2012 0.75
134 [CNS infections in immunocompetent patients]. Radiologe 2008 0.75
135 Evaluation of cerebral circulation by dynamic scintigraphy. Conn Med 1983 0.75
136 The mouse homolog of the human Miller-Dieker chromosomal region (MDCR) maps to mouse chromosome 11 in close proximity to Mov9 and D11Nds1. Mamm Genome 1995 0.75
137 Rapid structure elucidation of drug metabolites by use of stable isotopes. Xenobiotica 1973 0.75
138 [The effect of glucuronolactone on the comparative excretion of 17-ketosteroids, 17-hydroxycorticoids and glucuronic acid in infectious hepatitis]. Z Gesamte Inn Med 1967 0.75
139 [Human pharmacokinetics of AR-L 115 BS (author's transl)]. Arzneimittelforschung 1981 0.75
140 [Cranial birth trauma]. Radiologe 2009 0.75
141 Ultrasonographic pattern of spontaneous resolving fetal ovarian cyst: a case report. Clin Exp Obstet Gynecol 2014 0.75
142 The absorption, metabolism and excretion of (14C)-AR-L 115 BS in the baboon. Arzneimittelforschung 1981 0.75
143 Use of transgenic mice to study activation of retinoic acid-responsive promoters. Methods Enzymol 1997 0.75
144 [Pharmacokinetics of AR-L 115 BS in rabbits and dogs]. Arzneimittelforschung 1981 0.75
145 Discrimination and association processes for faces and non-faces: the effect of rotation. Acta Psychol (Amst) 1997 0.75
146 Novel ceruloplasmin mutation causing aceruloplasminemia with hepatic iron overload and diabetes without neurological symptoms. Clin Genet 2013 0.75
147 [Misuse of opioid analgesics. An internet analysis]. Schmerz 2014 0.75