Published in Am J Respir Crit Care Med on March 01, 2001
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med (2006) 2.47
Alveolar epithelial ion and fluid transport: recent progress. Am J Respir Cell Mol Biol (2006) 2.20
Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine. Crit Care Med (2006) 1.81
Alveolar edema fluid clearance and acute lung injury. Respir Physiol Neurobiol (2007) 1.43
Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation. Respir Res (2007) 1.29
Characterization of mouse alveolar epithelial cell monolayers. Am J Physiol Lung Cell Mol Physiol (2009) 1.20
miR-375 regulates rat alveolar epithelial cell trans-differentiation by inhibiting Wnt/β-catenin pathway. Nucleic Acids Res (2013) 1.11
Ion transport by pulmonary epithelia. J Biomed Biotechnol (2011) 1.05
Innate host defense of the lung: effects of lung-lining fluid pH. Lung (2004) 1.05
Mechanisms of alveolar epithelial translocation of a defined population of nanoparticles. Am J Respir Cell Mol Biol (2009) 1.04
An impaired alveolar-capillary barrier in vitro: effect of proinflammatory cytokines and consequences on nanocarrier interaction. J R Soc Interface (2009) 1.03
Hemoglobin is expressed in alveolar epithelial type II cells. Biochem Biophys Res Commun (2005) 1.03
Hyperoxia disrupts pulmonary epithelial barrier in newborn rats via the deterioration of occludin and ZO-1. Respir Res (2012) 1.01
Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication. Antioxid Redox Signal (2009) 0.94
Extracellular signal-regulated kinase (ERK) participates in the hypercapnia-induced Na,K-ATPase downregulation. FEBS Lett (2010) 0.90
Hypocapnic but not metabolic alkalosis impairs alveolar fluid reabsorption. Am J Respir Crit Care Med (2005) 0.86
Bronchiolar expression of aquaporin-3 (AQP3) in rat lung and its dynamics in pulmonary oedema. Pflugers Arch (2004) 0.82
Translocation of PEGylated quantum dots across rat alveolar epithelial cell monolayers. Int J Nanomedicine (2011) 0.81
Nanoparticle translocation across mouse alveolar epithelial cell monolayers: species-specific mechanisms. Nanomedicine (2013) 0.80
Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance. Am J Respir Cell Mol Biol (2016) 0.80
Effect of nanoparticles and environmental particles on a cocultures model of the air-blood barrier. Biomed Res Int (2012) 0.79
Respiratory physiology on a chip. Scientifica (Cairo) (2012) 0.78
Lung Edema Clearance: Relevance to Patients with Lung Injury. Rambam Maimonides Med J (2015) 0.77
Nasal potential difference to detect Na+ channel dysfunction in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2010) 0.77
Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization. J Heart Lung Transplant (2011) 0.75
The acute respiratory distress syndrome. N Engl J Med (2000) 25.38
The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell (1999) 11.59
An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis (1988) 7.43
Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 6.41
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med (1996) 4.54
Death and other complications of emergency airway management in critically ill adults. A prospective investigation of 297 tracheal intubations. Anesthesiology (1995) 3.87
TGF-beta is a critical mediator of acute lung injury. J Clin Invest (2001) 3.29
The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome. Crit Care Med (1999) 3.18
Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax (2008) 3.13
Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. J Biol Chem (1994) 2.85
Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema. Am J Respir Cell Mol Biol (2000) 2.81
Persistent paralysis in critically ill patients after long-term administration of vecuronium. N Engl J Med (1992) 2.68
Alveolar fluid clearance in the resected human lung. Am J Respir Crit Care Med (1994) 2.63
Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 2.57
Interobserver variability in applying a radiographic definition for ARDS. Chest (1999) 2.56
Plasma surfactant protein levels and clinical outcomes in patients with acute lung injury. Thorax (2003) 2.47
Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med (1995) 2.43
Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms. J Clin Invest (1995) 2.36
Protection from experimental ventilator-induced acute lung injury by IL-1 receptor blockade. Thorax (2007) 2.30
Differential responses of the endothelial and epithelial barriers of the lung in sheep to Escherichia coli endotoxin. J Clin Invest (1991) 2.17
Novel role for CFTR in fluid absorption from the distal airspaces of the lung. J Gen Physiol (2002) 2.16
Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis (1992) 2.11
Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med (1997) 2.10
Risk reduction in the intensive care unit. Am J Med (1998) 2.09
Effects of leukotriene B4 in the human lung. Recruitment of neutrophils into the alveolar spaces without a change in protein permeability. J Clin Invest (1989) 2.09
Lung fluid transport in aquaporin-5 knockout mice. J Clin Invest (2000) 2.07
Increased neutrophil numbers and IL-8 levels in airway secretions in acute severe asthma: Clinical and biologic significance. Am J Respir Crit Care Med (2000) 2.06
Prolonged neuromuscular blockade after long-term administration of vecuronium in two critically ill patients. Anesthesiology (1990) 2.06
Highly water-permeable type I alveolar epithelial cells confer high water permeability between the airspace and vasculature in rat lung. Proc Natl Acad Sci U S A (1998) 1.85
Beta-adrenergic agonists increase lung liquid clearance in anesthetized sheep. J Clin Invest (1987) 1.83
Stimulation of lung epithelial liquid clearance by endogenous release of catecholamines in septic shock in anesthetized rats. J Clin Invest (1994) 1.81
Alveolar epithelial fluid transport and the resolution of clinically severe hydrostatic pulmonary edema. J Appl Physiol (1985) (1999) 1.75
Comparison of transesophageal echocardiographic and scintigraphic estimates of left ventricular end-diastolic volume index and ejection fraction in patients following coronary artery bypass grafting. Anesthesiology (1990) 1.75
Differential liquid and protein clearance from the alveoli of anesthetized sheep. J Appl Physiol Respir Environ Exerc Physiol (1982) 1.74
Just say NO to inhaled nitric oxide for the acute respiratory distress syndrome. Crit Care Med (1998) 1.73
Elevated von Willebrand factor antigen is an early plasma predictor of acute lung injury in nonpulmonary sepsis syndrome. J Clin Invest (1990) 1.71
The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med (1998) 1.71
Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med (2000) 1.70
Evidence for a hydrostatic mechanism in human neurogenic pulmonary edema. Chest (1997) 1.70
Carbon dioxide permeability of aquaporin-1 measured in erythrocytes and lung of aquaporin-1 null mice and in reconstituted proteoliposomes. J Biol Chem (2000) 1.70
Transepithelial water permeability in microperfused distal airways. Evidence for channel-mediated water transport. J Clin Invest (1996) 1.68
Predictors of mortality in acute lung injury during the era of lung protective ventilation. Thorax (2008) 1.65
Alveolar epithelial injury and pleural empyema in acute P. aeruginosa pneumonia in anesthetized rabbits. J Appl Physiol (1985) (1993) 1.64
Noninvasive positive pressure ventilation for acute respiratory failure: underutilized or overrated? Chest (1997) 1.63
Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock. J Immunol (1993) 1.63
Acid-induced lung injury. Protective effect of anti-interleukin-8 pretreatment on alveolar epithelial barrier function in rabbits. Am J Respir Crit Care Med (1999) 1.62
Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice. J Clin Invest (1999) 1.60
Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc Natl Acad Sci U S A (1994) 1.59
Role of coagulation pathways and treatment with activated protein C in hyperoxic lung injury. Thorax (2008) 1.58
Early detection of type III procollagen peptide in acute lung injury. Pathogenetic and prognostic significance. Am J Respir Crit Care Med (1997) 1.57
Frequency and importance of barotrauma in 100 patients with acute lung injury. Crit Care Med (1995) 1.57
Aquaporin water channels and lung physiology. Am J Physiol Lung Cell Mol Physiol (2000) 1.50
Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donors. Am J Transplant (2012) 1.49
von Willebrand factor antigen is an independent marker of poor outcome in patients with early acute lung injury. Crit Care Med (2001) 1.45
Pulmonary edema fluid from patients with acute lung injury augments in vitro alveolar epithelial repair by an IL-1beta-dependent mechanism. Am J Respir Crit Care Med (2001) 1.45
Interleukin-8 mediates injury from smoke inhalation to both the lung endothelial and the alveolar epithelial barriers in rabbits. Am J Respir Crit Care Med (1999) 1.44
Alveolar epithelial fluid transport capacity in reperfusion lung injury after lung transplantation. Am J Respir Crit Care Med (1999) 1.44
Beta-adrenergic agonist stimulated alveolar fluid clearance in ex vivo human and rat lungs. Am J Respir Crit Care Med (1997) 1.43
Assessment of prognosis in patients with community-acquired pneumonia who require mechanical ventilation. Chest (2000) 1.43
Treatment of ARDS. Chest (2001) 1.37
Acute bacterial pneumonia in rats increases alveolar epithelial fluid clearance by a tumor necrosis factor-alpha-dependent mechanism. J Clin Invest (1997) 1.37
Clinical spectrum of pulmonary mucormycosis. Chest (1986) 1.35
Long-term clearance of liquid and protein from the lungs of unanesthetized sheep. J Appl Physiol (1985) (1985) 1.34
Severe sepsis--a new treatment with both anticoagulant and antiinflammatory properties. N Engl J Med (2001) 1.33
The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. Intensive Care Med (1998) 1.32
Alveolar liquid and protein clearance from normal dog lungs. J Appl Physiol (1985) (1988) 1.32
Obstetric patients requiring critical care. A five-year review. Chest (1992) 1.30
Alveolar liquid and protein clearance in anesthetized ventilated rats. J Appl Physiol (1985) (1994) 1.30
Increased levels of nitrate and surfactant protein a nitration in the pulmonary edema fluid of patients with acute lung injury. Am J Respir Crit Care Med (2001) 1.29
Interleukin-1beta augments in vitro alveolar epithelial repair. Am J Physiol Lung Cell Mol Physiol (2000) 1.29
Biologically active products of complement and acute lung injury in patients with the sepsis syndrome. Am Rev Respir Dis (1984) 1.28
Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice. J Physiol (2000) 1.27
The pulmonary physician in critical care. 5: Acute lung injury and the acute respiratory distress syndrome: definitions and epidemiology. Thorax (2002) 1.27
Increased interleukin-8 concentrations in the pulmonary edema fluid of patients with acute respiratory distress syndrome from sepsis. Crit Care Med (1996) 1.26
The ADP ribosyltransferase domain of Pseudomonas aeruginosa ExoT contributes to its biological activities. Infect Immun (2004) 1.25
Alveolar epithelial fluid transport in acute lung injury: new insights. Eur Respir J (2002) 1.24
Transalveolar osmotic and diffusional water permeability in intact mouse lung measured by a novel surface fluorescence method. J Gen Physiol (1996) 1.22
Prevalence and severity of neurologic dysfunction in critically ill patients. Influence on need for continued mechanical ventilation. Chest (1993) 1.22
Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium. Am J Physiol Lung Cell Mol Physiol (2001) 1.20
Relationship of interstitial fluid volume to alveolar fluid clearance in mice: ventilated vs. in situ studies. J Appl Physiol (1985) (2000) 1.20
Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and beta-agonist therapy. J Appl Physiol (1985) (1999) 1.19
Partial restoration of defective chloride conductance in DeltaF508 CF mice by trimethylamine oxide. Am J Physiol Lung Cell Mol Physiol (2001) 1.18
Inhibition of beta-adrenergic-dependent alveolar epithelial clearance by oxidant mechanisms after hemorrhagic shock. Am J Physiol (1999) 1.18
Hepatocyte growth factor and keratinocyte growth factor in the pulmonary edema fluid of patients with acute lung injury. Biologic and clinical significance. Am J Respir Crit Care Med (1998) 1.17
Initial severity of metabolic acidosis predicts the development of acute lung injury in severely traumatized patients. Crit Care Med (2000) 1.17
Contribution of amiloride-insensitive pathways to alveolar fluid clearance in adult rats. J Appl Physiol (1985) (2001) 1.17
Role of aquaporin water channels in airway fluid transport, humidification, and surface liquid hydration. J Gen Physiol (2001) 1.16
Elevated concentrations of leukotriene D4 in pulmonary edema fluid of patients with the adult respiratory distress syndrome. J Clin Immunol (1984) 1.16
Transforming growth factor-alpha enhances alveolar epithelial cell repair in a new in vitro model. Am J Physiol (1994) 1.16
Sharp increase in rat lung water channel expression in the perinatal period. Am J Respir Cell Mol Biol (1996) 1.14
Role of aquaporin water channels in pleural fluid dynamics. Am J Physiol Cell Physiol (2000) 1.12
Reactive nitrogen species inhibit alveolar epithelial fluid transport after hemorrhagic shock in rats. J Immunol (2001) 1.10
Hydrostatic versus increased permeability pulmonary edema: diagnosis based on radiographic criteria in critically ill patients. Radiology (1988) 1.10
Neurogenic pulmonary edema. Am Rev Respir Dis (1984) 1.10
Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. Am J Physiol Lung Cell Mol Physiol (2014) 1.09
Pseudomonas aeruginosa ExoT inhibits in vitro lung epithelial wound repair. Cell Microbiol (2001) 1.09
Acute pulmonary edema after lung transplantation: the pulmonary reimplantation response. Chest (1999) 1.08
Anti-IL-8 autoantibodies in alveolar fluid from patients with the adult respiratory distress syndrome. J Immunol (1996) 1.07
Alveolar and lung liquid clearance in anesthetized rabbits. J Appl Physiol (1985) (1991) 1.06
Activation of the stress protein response prevents the development of pulmonary edema by inhibiting VEGF cell signaling in a model of lung ischemia-reperfusion injury in rats. FASEB J (2006) 1.06